Goodwill and Intangible Assets - Gross Carrying Amounts and Net Book Values of Intangible Assets (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Dec. 31, 2016
Finite-Lived Intangible Assets [Line Items]
Gross Carrying Amount	$ 3,392,447	$ 1,491,768
Accumulated Amortization	(519,944)	(421,687)
Total	2,872,503	1,070,081
Indefinite-lived Intangible Assets [Line Items]
Gross Carrying Amount - Total Intangible Assets	3,538,979	3,433,688
Net Book Value - Total Intangible Assets	3,019,035	3,012,001
Acquired in-process research and development assets
Indefinite-lived Intangible Assets [Line Items]
In-process research and development	$ 146,532	1,941,920
Acquired developed technologies
Finite-Lived Intangible Assets [Line Items]
Remaining Weighted-Average Useful Life (in years)	15 years 1 month
Gross Carrying Amount	$ 3,376,895	1,477,618
Accumulated Amortization	(505,369)	(410,523)
Total	$ 2,871,526	1,067,095
Manufacturing contracts
Finite-Lived Intangible Assets [Line Items]
Remaining Weighted-Average Useful Life (in years)	7 months 18 days
Gross Carrying Amount	$ 12,647	11,278
Accumulated Amortization	(11,670)	(8,292)
Total	$ 977	2,986
Trademarks
Finite-Lived Intangible Assets [Line Items]
Remaining Weighted-Average Useful Life (in years)	0 years
Gross Carrying Amount	$ 2,905	2,872
Accumulated Amortization	(2,905)	(2,872)
Total	$ 0	$ 0