Certain Balance Sheet Items (Tables)

6 Months Ended

Jun. 30, 2017

Certain Balance Sheet Items [Abstract]

Property and Equipment

Property and equipment consisted of the following (in thousands):

	June 30, 2017			December 31, 2016
Construction-in-progress	$	60,347		$	33,427
Land and buildings	46,246			46,033
Manufacturing equipment and machinery	20,397			19,596
Computer software	19,218			17,832
Leasehold improvements	12,549			9,328
Computer equipment	12,172			10,980
Furniture and fixtures	3,372			2,436
Subtotal	174,301			139,632
Less accumulated depreciation and amortization	(37,675		)	(32,142		)
Property and equipment, net	$	136,626		$	107,490

Accrued Liabilities

Accrued liabilities consisted of the following (in thousands):

	June 30, 2017		December 31, 2016
Rebates and other sales deductions	$	74,829	$	72,344
Employee compensation and benefits	39,367		43,363
Royalties	8,937		11,643
Accrued construction-in-progress	6,833		1,597
Accrued interest	4,747		5,179
Sales returns reserve	4,032		4,366
Selling and marketing accruals	3,517		3,924
Professional fees	3,438		4,596
Inventory-related accruals	2,657		3,350
Clinical trial accruals	2,393		10,139
Accrued contract termination fees	—		11,612
Other	18,951		21,155
Total accrued liabilities	$	169,701	$	193,268