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Goodwill and Intangible Assets
3 Months Ended
Mar. 31, 2017
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Intangible Assets
Goodwill and Intangible Assets
The gross carrying amount of goodwill was as follows (in thousands):
Balance at December 31, 2016
$
893,810

Foreign exchange
5,480

Balance at March 31, 2017
$
899,290


The gross carrying amounts and net book values of our intangible assets were as follows (in thousands): 
 
March 31, 2017
 
December 31, 2016
 
Remaining
Weighted-
Average Useful
Life
(In years)
 
Gross
Carrying
Amount
 
Accumulated
Amortization
 
Net Book
Value
 
Gross
Carrying
Amount
 
Accumulated
Amortization
 
Net Book
Value
Acquired developed technologies
11.1

 
$
1,491,720

 
$
(438,983
)
 
$
1,052,737

 
$
1,477,618

 
$
(410,523
)
 
$
1,067,095

Manufacturing contracts
0.8

 
11,434

 
(9,121
)
 
2,313

 
11,278

 
(8,292
)
 
2,986

Trademarks

 
2,876

 
(2,876
)
 

 
2,872

 
(2,872
)
 

Total finite-lived intangible assets
 
 
1,506,030

 
(450,980
)
 
1,055,050

 
1,491,768

 
(421,687
)
 
1,070,081

Acquired in-process research and development assets
 
 
1,943,730

 

 
1,943,730

 
1,941,920

 

 
1,941,920

Total intangible assets
 
 
$
3,449,760

 
$
(450,980
)
 
$
2,998,780

 
$
3,433,688

 
$
(421,687
)
 
$
3,012,001


The assumptions and estimates used to determine future cash flows and remaining useful lives of our intangible and other long-lived assets are complex and subjective. They can be affected by various factors, including external factors, such as industry and economic trends, and internal factors such as changes in our business strategy and our forecasts for specific product lines.
Based on finite-lived intangible assets recorded as of March 31, 2017, and assuming the underlying assets will not be impaired and that we will not change the expected lives of the assets, future amortization expenses were estimated as follows (in thousands): 
Year Ending December 31,
Estimated
Amortization  
Expense
2017 (remainder)
$
77,309

2018
100,336

2019
100,123

2020
98,980

2021
98,044

Thereafter
580,258

Total
$
1,055,050