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Net loss per share (Tables)
12 Months Ended
Dec. 31, 2021
Net loss per share [Abstract]  
Anti-dilutive Securities Excluded from Computation of Net Loss per Share
The following potential common shares were not considered in the computation of diluted net loss per share as their effect would have been anti-dilutive for the year end periods presented below:
 
   
2021
   
2020
 
Series A, Series B and RDO warrants
   
7,282,999
      6,331,674  
Stock options
   
2,096,836
     
1,784,198
 
Restricted stock awards including pending issuances of stock for services
   
6,970
     
40,000
 
Former Rexahn warrants
   
66,538
      66,538  
Former Rexahn options
   
82
      123