0001012975-19-000177.txt : 20190214 0001012975-19-000177.hdr.sgml : 20190214 20190214163050 ACCESSION NUMBER: 0001012975-19-000177 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20181231 FILED AS OF DATE: 20190214 DATE AS OF CHANGE: 20190214 EFFECTIVENESS DATE: 20190214 FILER: COMPANY DATA: COMPANY CONFORMED NAME: PERCEPTIVE ADVISORS LLC CENTRAL INDEX KEY: 0001224962 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10438 FILM NUMBER: 19607082 BUSINESS ADDRESS: STREET 1: 51 ASTOR PLACE, 10TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10003 BUSINESS PHONE: 646-205-5300 MAIL ADDRESS: STREET 1: 51 ASTOR PLACE, 10TH FLOOR CITY: NEW YORK STATE: NY ZIP: 10003 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001224962 XXXXXXXX 12-31-2018 12-31-2018 PERCEPTIVE ADVISORS LLC

51 ASTOR PLACE, 10TH FLOOR NEW YORK NY 10003

13F HOLDINGS REPORT 028-10438 N Joseph Edelman 646-205-5342 /s/ Joseph Edelman New York NY 02-14-2019 0 101 2627578 false INFORMATION TABLE 2 infotable.xml INFORMATION TABLE ABEONA THERAPEUTICS INC W EXP12/24/201 00289Y115 1267 659636 SH SOLE 659636 0 0 ABEONA THERAPEUTICS INC COM 00289Y107 1269 180797 SH SOLE 180797 0 0 ACASTI PHARMA INC CL A NEW 00430K402 1480 1779882 SH SOLE 1779882 0 0 ACCELERON PHARMA INC COM 00434H108 39938 905017 SH SOLE 905017 0 0 ADMA BIOLOGICS INC COM 000899104 14542 6521102 SH SOLE 6521102 0 0 ADVERUM BIOTECHNOLOGIES INC COM 00773U108 960 300000 SH SOLE 300000 0 0 AKEBIA THERAPEUTICS INC COM 00972D105 9182 1703440 SH SOLE 1703440 0 0 ALBIREO PHARMA INC COM 01345P106 39506 1704330 SH SOLE 1704330 0 0 ALDEYRA THERAPEUTICS INC COM 01438T106 24684 3085458 SH SOLE 3085458 0 0 ALLENA PHARMACEUTICALS INC COM 018119107 704 132300 SH SOLE 132300 0 0 ALLIQUA BIOMEDICAL INC COM PAR 019621309 214 114730 SH SOLE 114730 0 0 ALLOGENE THERAPEUTICS INC COM 019770106 41574 1543790 SH SOLE 1543790 0 0 ALNYLAM PHARMACEUTICALS INC COM 02043Q107 18462 262241 SH SOLE 262241 0 0 AMARIN CORP PLC SPONS ADR NEW 023111206 64553 4875600 SH SOLE 4875600 0 0 AMEDISYS INC COM 023436108 422 3672 SH SOLE 3672 0 0 AMICUS THERAPEUTICS INC COM 03152W109 191701 20724424 SH SOLE 20724424 0 0 ANI PHARMACEUTICALS INC NOTE 3.000%12/0 00182CAA1 7383 7500000 PRN SOLE 7500000 0 0 AQUESTIVE THERAPEUTICS INC COM 3843E1047 13314 2113400 SH SOLE 2113400 0 0 ARENA PHARMACEUTICALS INC COM NEW 040047607 55605 1430171 SH SOLE 1430171 0 0 ARGENX SE SPONSORED ADR 04016X101 53889 560941 SH SOLE 560941 0 0 ARROWHEAD PHARMACEUTICALS INC COM 04280A100 3582 300000 SH SOLE 300000 0 0 ASCENDIS PHARMA A S SPONSORED ADR 04351P101 63043 1052647 SH SOLE 1052647 0 0 ATHENEX INC COM 04685N103 32550 5096022 SH SOLE 5096022 0 0 AXONICS MODULATION TECH INC COM 05465P101 10935 751000 SH SOLE 751000 0 0 BLUEPRINT MEDICINES CORP COM 09627Y109 43484 857326 SH SOLE 857326 0 0 CAREDX INC COM 14167L103 1037 44128 SH SOLE 44128 0 0 CLEMENTIA PHARMACEUTICALS INC COM 185575107 17640 1500000 SH SOLE 1500000 0 0 COLLEGIUM PHARMACEUTICAL INC COM 19459J104 7374 445000 SH SOLE 445000 0 0 CONCERT PHARMACEUTICALS INC COM 206022105 22823 1873779 SH SOLE 1873779 0 0 CRINETICS PHARMACEUTICALS INC COM 22663K107 77612 2587953 SH SOLE 2587953 0 0 CYMABAY THERAPEUTICS INC COM 23257D103 19382 2462821 SH SOLE 2462821 0 0 CYTOMX THERAPEUTICS INC COM 23284F105 43588 2911715 SH SOLE 2911715 0 0 DBV TECHNOLOGIES S A SPONSORED ADR 23306J101 5309 826960 SH SOLE 826960 0 0 DEXCOM INC COM 252131107 442 3733 SH SOLE 3733 0 0 DOVA PHARMACEUTICALS INC COM 25985T102 23693 3125851 SH SOLE 3125851 0 0 EDIOS THERAPEUTICS INC COM 28249H104 9452 686922 SH SOLE 686922 0 0 EHEALTH INC COM 28238P109 2113 55021 SH SOLE 55021 0 0 EIGER BIOPHARMACEUTICALS INC COM 28249U105 1421 139890 SH SOLE 139890 0 0 ESTABLISHMENT LABS HLDGS INC COM G31249108 15878 614242 SH SOLE 614242 0 0 FERRARI N.V. COM N3167Y103 610 6200 SH SOLE 6200 0 0 FIAT CHRYSLER AUTOMOBILES N. 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SHS EURO N71542109 11250 722523 SH SOLE 722523 0 0 PROTAGONIST THERAPEUTICS INC COM 4366E1029 9190 1365579 SH SOLE 1365579 0 0 QUOTIENT LTD COM G73268107 66029 10789054 SH SOLE 10789054 0 0 REGENXBIO INC COM 75901B107 26894 645726 SH SOLE 645726 0 0 RETROPHIN INC COM 761299106 49782 3342038 SH SOLE 3342038 0 0 RHYTHM PHARMACEUTICALS INC COM 76243J105 13763 509186 SH SOLE 509186 0 0 ROCKET PHARMACEUTICALS INC COM 77313F106 3495 240173 SH SOLE 240173 0 0 SAGE THERAPEUTICS INC COM 78667J108 13110 147315 SH SOLE 147315 0 0 SI-BONE INC COM 825704109 307 15000 SH SOLE 15000 0 0 SIERRA ONCOLOGY INC COM 82640U107 3413 2666190 SH SOLE 2666190 0 0 SOLID BIOSCIENCES INC COM 83422E105 14 1835 SH Call SOLE 1835 0 0 SOLID BIOSCIENCES INC COM 83422E105 105249 3927222 SH SOLE 3927222 0 0 STAAR SURGICAL CO COM PAR $ 0.01 852312305 405 12953 SH SOLE 12953 0 0 SYNLOGIC INC COM 87166L100 6049 867852 SH SOLE 867852 0 0 TANDEM DIABETES CARE INC COM NEW 875372203 479 12844 SH SOLE 12844 0 0 TELADOC HEALTH INC COM 87918A105 2974 60000 SH SOLE 60000 0 0 THERAPEUTICSMD INC COM 88338N107 5715 1500000 SH SOLE 1500000 0 0 TRANSLATE BIO INC COM 89374L104 3167 435000 SH SOLE 435000 0 0 UNIQURE NV SHS N90064101 5946 220707 SH SOLE 220707 0 0 UROVANT SCIENCES LTD SHS G9381B108 3915 625359 SH SOLE 625359 0 0 VACCINEX INC COM 918640103 190 50000 SH SOLE 50000 0 0 VAPOTHERM INC COM 922107107 24464 1226315 SH SOLE 1226315 0 0 VBI VACCINES INC COM NEW 91822J103 38322 23951556 SH SOLE 23951556 0 0 VERICEL CORP COM 92346J108 488 28090 SH SOLE 28090 0 0 VERRICA PHARMACEUTICALS INC COM 92511W108 27794 3410412 SH SOLE 3410412 0 0 VERU INC COM 92536C103 1853 1425000 SH SOLE 1425000 0 0 VIEWRAY INC COM 92672L107 21715 3905650 SH SOLE 3905650 0 0 WAVE LIFE SCIENCES LTD SHS Y95308105 2501 59498 SH SOLE 59498 0 0 XENCOR INC COM 98401F105 6833 196810 SH SOLE 196810 0 0 ZOGENIX INC COM 98978L204 138191 3790216 SH SOLE 3790216 0 0 ZOGENIX INC COM 98978L204 410 200000 SH Put SOLE 200000 0 0 ZYMEWORKS INC COM 98985W102 7196 573890 SH SOLE 573890 0 0