Summary of Significant Accounting Policies (Details) - shares	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Potentially dilute securities excluded from calculation	1,731,170	1,563,672
Convertible preferred stock [Member]
Potentially dilute securities excluded from calculation	2,926	2,926
Warrants to purchase common stock [Member]
Potentially dilute securities excluded from calculation	1,249,754	1,251,709
Options to purchase common stock [Member]
Potentially dilute securities excluded from calculation	478,490	309,037