10-Q

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C.  20549

FORM 10-Q

(Mark One)
ý	QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended September 30, 2016

or

¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from______________to __________

Commission file number 1-7928

BIO-RAD LABORATORIES, INC.

(Exact name of registrant as specified in its charter)

Delaware	94-1381833
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification No.)
1000 Alfred Nobel Drive, Hercules, California	94547
(Address of principal executive offices)	(Zip Code)

(510) 724-7000

(Registrant's telephone number, including area code)

No Change

(Former name, former address and former fiscal year, if changed since last report.)

Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

Yes    x      No     o

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232,405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).

Yes    x      No     o

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company.  See definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.  (Check one):

Large accelerated filer	x		Accelerated filer	o
Non-accelerated filer	o	(Do not check if smaller reporting company)	Smaller reporting company	o

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

Yes    o      No     x

Indicate the number of shares outstanding of each of the issuer’s classes of common stock, as of the latest practicable date.

Title of Class	Shares Outstanding at October 27, 2016
Class A Common Stock, Par Value $0.0001 per share	24,417,421
Class B Common Stock, Par Value $0.0001 per share	5,123,819

BIO-RAD LABORATORIES, INC.

FORM 10-Q SEPTEMBER 30, 2016

TABLE OF CONTENTS

Part I – Financial Information	4
Item 1. Financial Statements	4
Condensed Consolidated Balance Sheets	4
Condensed Consolidated Statements of Income	5
Condensed Consolidated Statements of Comprehensive Income	6
Condensed Consolidated Statements of Cash Flows	7
Notes to Condensed Consolidated Financial Statements	8
Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations	27
Item 3. Quantitative and Qualitative Disclosures about Market Risk	36
Item 4. Controls and Procedures	37
Part II – Other Information	37
Item 1. Legal Proceedings	37
Item 1A. Risk Factors	38
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds	49
Item 3. Defaults Upon Senior Securities	49
Item 4. Mine Safety Disclosures	49
Item 5. Other Information	49
Item 6. Exhibits	50
Signatures	51

2

INFORMATION RELATING TO FORWARD-LOOKING STATEMENTS

Other than statements of historical fact, statements made in this report include forward-looking statements, such as statements with respect to our future financial performance, operating results, plans and objectives that involve risk and uncertainties.  Forward-looking statements generally can be identified by the use of forward-looking terminology, such as “believe,” “expect,” “anticipate,” “may,” “will,” “intend,” “estimate,” “continue,” or similar expressions or the negative of those terms or expressions.  Such statements involve risks and uncertainties, which could cause actual results to vary materially from those expressed in or indicated by the forward-looking statements.  We have based these forward-looking statements on our current expectations and projections about future events.  However, actual results may differ materially from those currently anticipated depending on a variety of risk factors including, but not limited to, those identified under “Part II, Item 1A, Risk Factors” of this Quarterly Report on Form 10-Q. We caution you not to place undue reliance on forward-looking statements, which reflect an analysis only and speak only as of the date hereof.  We undertake no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise, except as required by law.

3

PART I – FINANCIAL INFORMATION

BIO-RAD LABORATORIES, INC.

Condensed Consolidated Balance Sheets

(In thousands, except share data)

	September 30, 2016			December 31, 2015
ASSETS:	(Unaudited)
Cash and cash equivalents	$	417,939		$	457,549
Short-term investments	388,177			328,718
Restricted investments	4,210			4,210
Accounts receivable, net	367,662			391,485
Inventories:
Raw materials	117,562			109,928
Work in process	130,964			114,438
Finished goods	307,832			265,858
Total inventories	556,358			490,224
Other current assets	115,757			105,410
Total current assets	1,850,103			1,777,596
Property, plant and equipment, at cost	1,217,176			1,117,086
Less: accumulated depreciation and amortization	(742,509		)	(679,396		)
Property, plant and equipment, net	474,667			437,690
Goodwill, net	506,573			495,948
Purchased intangibles, net	220,904			214,026
Other investments	903,658			719,840
Other assets	63,821			64,618
Total assets	$	4,019,726		$	3,709,718
LIABILITIES AND STOCKHOLDERS’ EQUITY:
Accounts payable, accrued payroll and employee benefits	$	280,453		$	280,248
Current maturities of long-term debt and notes payable	297			298
Income and other taxes payable	22,274			29,339
Other current liabilities	139,694			131,466
Total current liabilities	442,718			441,351
Long-term debt, net of current maturities	434,137			433,883
Deferred income taxes	295,245			233,475
Deferred revenue	4,400			3,743
Other long-term liabilities	140,535			106,763
Total liabilities	1,317,035			1,219,215
Stockholders’ equity:
Class A common stock, shares issued 24,417,541 and 24,230,448 at 2016 and 2015, respectively; shares outstanding 24,417,419 and 24,230,326 at 2016 and 2015, respectively	2			2
Class B common stock, shares issued 5,124,738 and 5,130,558 at 2016 and 2015, respectively; shares outstanding 5,123,821 and 5,129,641 at 2016 and 2015, respectively	1			1
Additional paid-in capital	324,636			300,408
Class A treasury stock at cost, 122 shares at 2016 and 2015	(12		)	(12		)
Class B treasury stock at cost, 917 shares at 2016 and 2015	(89		)	(89		)
Retained earnings	1,856,750			1,808,055
Accumulated other comprehensive income	521,403			382,138
Total stockholders’ equity	2,702,691			2,490,503
Total liabilities and stockholders’ equity	$	4,019,726		$	3,709,718

The accompanying notes are an integral part of these condensed consolidated financial statements. 

4

BIO-RAD LABORATORIES, INC.

Condensed Consolidated Statements of Income

(In thousands, except per share data)

(Unaudited)

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Net sales	$	508,745		$	469,961		$	1,496,719		$	1,448,884
Cost of goods sold	229,276			206,509			672,989			635,729
Gross profit	279,469			263,452			823,730			813,155
Selling, general and administrative expense	201,452			187,445			596,704			568,845
Research and development expense	49,924			43,336			150,681			137,085
Income from operations	28,093			32,671			76,345			107,225
Interest expense	5,634			5,822			16,846			15,658
Foreign currency exchange losses, net	1,210			2,166			3,576			8,910
Other (income) expense, net	(1,439		)	(732		)	(13,824		)	(8,992		)
Income before income taxes	22,688			25,415			69,747			91,649
Provision for income taxes	(4,283		)	(8,045		)	(21,052		)	(28,038		)
Net income	$	18,405		$	17,370		$	48,695		$	63,611
Basic earnings per share:
Net income per basic share	$	0.63		$	0.59		$	1.66		$	2.18
Weighted average common shares - basic	29,444			29,195			29,402			29,141
Diluted earnings per share:
Net income per diluted share	$	0.62		$	0.59		$	1.65		$	2.17
Weighted average common shares - diluted	29,671			29,439			29,592			29,372

The accompanying notes are an integral part of these condensed consolidated financial statements. 

5

BIO-RAD LABORATORIES, INC.

Condensed Consolidated Statements of Comprehensive Income

(In thousands)

(Unaudited)

	Three Months Ended					Nine Months Ended
	September 30,					September 30,
	2016		2015			2016			2015
Net income	$	18,405	$	17,370		$	48,695		$	63,611
Other comprehensive income:
Foreign currency translation adjustments	3,423		(27,743		)	22,936			(10,147		)
Foreign other post-employment benefits adjustments, net of income taxes	32		89			(73		)	513
Net unrealized holding gains on available-for-sale (AFS) investments, net of income taxes	58,387		74,987			116,402			170,069
Other comprehensive income, net of income taxes	61,842		47,333			139,265			160,435
Comprehensive income	$	80,247	$	64,703		$	187,960		$	224,046

The accompanying notes are an integral part of these condensed consolidated financial statements.

6

BIO-RAD LABORATORIES, INC.

Condensed Consolidated Statements of Cash Flows

(In thousands, unaudited)

	Nine Months Ended
	September 30,
	2016			2015
Cash flows from operating activities:
Cash received from customers	$	1,530,605		$	1,443,672
Cash paid to suppliers and employees	(1,365,548		)	(1,278,255		)
Interest paid, net	(11,195		)	(9,620		)
Income tax payments, net	(37,373		)	(15,646		)
Investment proceeds and miscellaneous receipts, net	14,360			9,695
Excess tax benefits from share-based compensation	(1,094		)	(3,242		)
(Payments for) proceeds from forward foreign exchange contracts, net	(8,441		)	3,654
Net cash provided by operating activities	121,314			150,258
Cash flows from investing activities:
Capital expenditures	(96,323		)	(84,013		)
Proceeds from dispositions of property, plant and equipment	378			41
Payments for acquisition and long-term investment	(11,785		)	(3,490		)
Payments for purchases of intangible assets	(6		)	(1,375		)
Payments for purchases of marketable securities and investments	(217,820		)	(172,440		)
Proceeds from sales of marketable securities and investments	59,687			56,630
Proceeds from maturities of marketable securities and investments	102,112			121,556
Net cash used in investing activities	(163,757		)	(83,091		)
Cash flows from financing activities:
Net borrowings from line-of-credit arrangements and notes payable	—			74
Payments on long-term borrowings	(231		)	(206		)
Payments of contingent consideration	(3,500		)	(2,983		)
Proceeds from issuances of common stock for share-based compensation	8,828			4,726
Excess tax benefits from share-based compensation	1,094			3,242
Net cash provided by financing activities	6,191			4,853
Effect of foreign exchange rate changes on cash	(3,358		)	22,058
Net (decrease) increase in cash and cash equivalents	(39,610		)	94,078
Cash and cash equivalents at beginning of period	457,549			413,251
Cash and cash equivalents at end of period	$	417,939		$	507,329
Reconciliation of net income to net cash provided by operating activities:
Net income	$	48,695		$	63,611
Adjustments to reconcile net income to net cash provided by operating activities:
Depreciation and amortization	110,156			97,970
Share-based compensation	14,318			12,309
Gains on dispositions of securities	(93		)	(19		)
Excess tax benefits from share-based compensation	(1,094		)	(3,242		)
Changes in fair value of contingent consideration	(2,164		)	(730		)
Decrease in accounts receivable	32,650			16,996
Increase in inventories	(67,938		)	(67,609		)
(Increase) decrease in other current assets	(2,018		)	2,620
(Decrease) increase in accounts payable and other current liabilities	(4,645		)	17,869
(Decrease) increase in income taxes payable	(8,423		)	14,760
(Decrease) increase in deferred income taxes	(8,480		)	2,350
Net decrease/increase in other long-term assets/liabilities	10,350			(6,627		)
Net cash provided by operating activities	$	121,314		$	150,258

The accompanying notes are an integral part of these condensed consolidated financial statements.

7

BIO-RAD LABORATORIES, INC

Notes to Condensed Consolidated Financial Statements

(Unaudited)

1.BASIS OF PRESENTATION AND USE OF ESTIMATES

Basis of Presentation

In this report, “Bio-Rad,” “we,” “us,” “the Company” and “our” refer to Bio-Rad Laboratories, Inc. and its subsidiaries.  The accompanying unaudited condensed consolidated financial statements of Bio-Rad have been prepared in accordance with accounting principles generally accepted in the United States of America (GAAP) and reflect all adjustments which are, in the opinion of management, necessary to fairly state the results of the interim periods presented.  All such adjustments are of a normal recurring nature. Results for the interim period are not necessarily indicative of the results for the entire year.  The condensed consolidated balance sheet at December 31, 2015 has been derived from the audited consolidated financial statements at that date but does not include all of the information and footnotes required by GAAP for complete financial statements. The condensed consolidated financial statements should be read in conjunction with the notes to the consolidated financial statements contained in our Annual Report on Form 10-K for the year ended December 31, 2015.

We evaluate subsequent events and the evidence they provide about conditions existing at the date of the balance sheet as well as conditions that arose after the balance sheet date but through the date the financial statements are issued.  The effects of conditions that existed at the balance sheet date are recognized in the financial statements. Events and conditions arising after the balance sheet date but before the financial statements are issued are evaluated to determine if disclosure is required to keep the financial statements from being misleading.  To the extent such events and conditions exist, disclosures are made regarding the nature of events and the estimated financial effects of those events and conditions.

Use of Estimates

The preparation of the condensed consolidated financial statements requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingencies at the date of the financial statements as well as the reported amounts of revenues and expenses during the reporting periods. Bio-Rad bases its estimates on historical experience and on various other market-specific and other relevant assumptions that are believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Actual results could differ materially from those estimates.

Recent Accounting Standards Updates

In October 2016, Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update No. (“ASU”) 2016-16, "Intra-Entity Transfers of Assets Other Than Inventory." ASU 2016-16 requires immediate recognition of income tax consequences of intercompany asset transfers, other than inventory transfers.  Existing GAAP prohibits recognition of income tax consequences of intercompany asset transfers whereby the seller defers any net tax effect and the buyer is prohibited from recognizing a deferred tax asset on the difference between the newly created tax basis of the asset in its tax jurisdiction and its financial statement carrying amount as reported in the consolidated financial statements.  ASU 2016-16 specifically excludes from its scope intercompany inventory transfers whereby the recognition of tax consequences will take place when the inventory is sold to third parties. ASU 2016-16 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted as of the beginning of an annual reporting period for which financial statements have not been issued or made available for issuance. We are currently evaluating the effect ASU 2016-16 will have on our consolidated financial statements.

8

In August 2016, FASB issued ASU 2016-15, "Classification of Certain Cash Receipts and Cash Payments." ASU 2016-15 is intended to reduce diversity in practice in how certain transactions are classified in the statement of cash flows. ASU 2016-15 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years, with early adoption permitted. We are currently evaluating the effect ASU 2016-15 will have on our consolidated statements of cash flows.

In June 2016, the FASB issued ASU 2016-13, "Measurement of Credit Losses on Financial Instruments." ASU 2016-13 will replace the current incurred loss approach with an expected loss model for instruments measured at amortized cost and require entities to record allowances for available-for-sale debt securities rather than reduce the carrying amount under the current other-than-temporary impairment model. ASU 2016-13 is effective for fiscal years beginning after December 15, 2019, and interim periods within those fiscal years. Early adoption is permitted for all entities for annual periods beginning after December 15, 2018, and interim periods therein. We are currently evaluating the effect ASU 2016-13 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-09, "Improvements to Employee Share-Based Payment Accounting." ASU 2016-09 will require all income tax effects of awards to be recognized in the income statement when the awards vest or are settled. It also will allow an employer to repurchase more of an employee’s shares than it can today for tax withholding purposes without triggering liability accounting and to make a policy election to account for forfeitures as they occur. ASU 2016-09 is effective for fiscal years beginning after December 15, 2016, and interim periods within those fiscal years and early adoption is permitted. We are currently evaluating the effect ASU 2016-09 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-07, "Simplifying the Transition to the Equity Method of Accounting," which eliminates the requirement to retrospectively apply the equity method in previous periods when an investor initially obtains significant influence over an investee. Under current guidance, an investor that doesn’t consolidate an investment and initially accounts for it under a method other than the equity method is required to retrospectively apply the equity method in prior periods in which it held the investment when it subsequently obtained significant influence. ASU 2016-07 will be applied on a prospective basis and is effective for all entities for fiscal years beginning after December 15, 2016, and interim periods within those years and early adoption is permitted. We do not plan to early adopt ASU 2016-07 and currently do not expect it to affect our consolidated financial statements when adopted on January 1, 2017.

In February 2016, the FASB issued ASU 2016-02, "Leases," which will require, among other items, lessees to recognize most leases as assets and liabilities on the balance sheet. Qualitative and quantitative disclosures will be enhanced to better understand the amount, timing and uncertainty of cash flows arising from leases. ASU 2016-02 is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years, with early adoption permitted. We do not plan to early adopt. ASU 2016-02 will be adopted on a modified retrospective basis, with elective reliefs, which requires application of ASU 2016-02 for all periods presented. We are currently evaluating the effect ASU 2016-02 will have on our consolidated financial statements.

In January 2016, the FASB issued ASU 2016-01, "Recognition and Measurement of Financial Assets and Financial Liabilities." Amendments under ASU 2016-01, among other items, require that all equity investments in unconsolidated entities (other than those accounted for using the equity method of accounting) will generally be measured at fair value through earnings. There will no longer be an available-for-sale classification, for which changes in fair value are reported in other comprehensive income, for equity securities with readily determinable fair values. For equity investments without readily determinable fair values, the cost method is also eliminated. However, entities will be able to elect to record equity investments without readily determinable fair values at cost, less impairment, and plus or minus subsequent adjustments for observable price changes. Changes in the basis of these equity investments will be reported in current earnings. ASU 2016-01 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. We are currently evaluating the effect ASU 2016-01 will have, if any, on our consolidated financial statements.

9

In September 2015, the FASB issued ASU 2015-16, "Simplifying the Accounting for Measurement-Period Adjustments," which eliminates the requirement for an acquirer in a business combination to account for measurement-period adjustments retrospectively. Under ASU 2015-16, acquirers must recognize measurement-period adjustments during the period in which they determine the amounts, including the effect on earnings of any amounts they would have recorded in previous periods if the accounting had been completed at the acquisition date. The measurement period cannot exceed one year from the date of the acquisition. ASU 2015-16 was effective on January 1, 2016, and we adopted it at the same time as a change in accounting policy, which had no impact on our consolidated financial statements.

In July 2015, the FASB issued ASU 2015-11, “Simplifying the Measurement of Inventory.” Under current guidance, an entity subsequently measures inventory at the lower of cost or market, with market defined as replacement cost, net realizable value (NRV), or NRV less a normal profit margin. An entity uses current replacement cost provided that it is not above NRV (i.e., the ceiling) or below NRV less an “approximately normal profit margin” (i.e., the floor). ASU 2015-11 eliminates this analysis and requires entities to measure most inventory “at the lower of cost and NRV.” ASU 2015-11 is effective prospectively for annual periods beginning after December 15, 2016, and interim periods therein, with early adoption permitted. We will not early adopt. We do not expect ASU 2015-11 to have a material impact to our consolidated financial statements when adopted on January 1, 2017.

In April 2015, the FASB issued ASU 2015-03, "Simplifying the Presentation of Debt Issuance Costs." ASU 2015-03 was issued to simplify the presentation of debt issuance costs by requiring debt issuance costs to be presented as a deduction from the corresponding debt liability. This makes the presentation of debt issuance costs consistent with the presentation of debt discounts or premiums. Under prior U.S. GAAP, debt issuance costs were reported on the balance sheet as assets and amortized as interest expense. Under ASU 2015-03, debt issuance costs will continue to be amortized to interest expense using the effective interest method. In August 2015, the FASB issued ASU 2015-15, "Presentation and Subsequent Measurement of Debt Issuance Costs Associated with Line-of-Credit Arrangements" to clarify the SEC staff’s position that it would not object to an entity deferring and presenting debt issuance costs as an asset and subsequently amortizing the deferred debt issuance costs ratably over the term of the line-of-credit arrangement, which is our current practice. We adopted ASU 2015-03 on January 1, 2016 on a retrospective basis as a change in accounting policy. The Condensed Consolidated Balance Sheet as of December 31, 2015, was retrospectively adjusted by decreasing Other assets and Long-term debt, net of current maturities by $1.8 million, respectively.

In May 2014, the FASB issued ASU 2014-09, “Revenue from Contracts with Customers,” which requires an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. ASU 2014-09 will replace most existing revenue recognition guidance in GAAP when it becomes effective. In August 2015, the FASB issued ASU 2015-14 to defer the effective date for annual reporting periods beginning after December 15, 2017, including interim periods within that reporting period. Early adoption is permitted as of the original effective date in ASU 2014-09, which is annual reporting periods beginning after December 15, 2016, however, we will not early adopt. In May 2016, the FASB issued ASU 2016-12, "Narrow-Scope Improvements and Practical Expedients," which amends and clarifies certain aspects in ASU 2014-09 that include collectiblity, presentation of sales and other taxes collected from customers, noncash consideration, contract modifications and completed contracts at transition. In April 2016, the FASB issued ASU 2016-10, "Identifying Performance Obligations and Licensing," which amends the guidance in ASU 2014-09 on accounting for licenses of intellectual property and identifying performance obligations. In March 2016, The FASB issued ASU 2016-08, "Principal versus Agent Considerations (Reporting Revenue Gross versus Net)," which amends the principal versus agent guidance in ASU 2014-09. The standards are to be applied retrospectively and permit the use of either the retrospective or cumulative effect transition method. We will use the cumulative effect transition method once we adopt ASUs 2014-09, 2016-12, 2016-10 and 2016-08 on January 1, 2018. We are currently evaluating the effect that these ASUs will have on our consolidated financial statements and related disclosures.

10

2.ACQUISITIONS

Propel Labs, Inc.

In January 2016, we acquired a high performance analytical flow cytometer platform from Propel Labs (Propel) that will enable advanced and novice users to perform basic and multi-parameter cytometry for a wide range of applications and chemistries. This asset acquisition was accounted for as a business combination, as the new analytical flow cytometer platform represented an integrated set of activities and assets that is capable of being conducted and managed for the purpose of providing a return and therefore constitutes a business in accordance with GAAP. The amount of the acquisition-related cost was minimal as Bio-Rad primarily represented itself during the acquisition process. This business acquisition is included in our Life Science segment’s results of operations from the acquisition date.

The fair value of the consideration as of the acquisition date was $38.8 million, which included $9.5 million paid in cash at the closing date and $29.3 million in contingent consideration potentially payable to Propel. The contingent consideration was based on a probability-weighted income approach related to the achievement of certain sales milestones, and was recognized at its estimated fair value of $29.3 million as of September 30, 2016 (see Note 3, "Fair Value Measurements").

The final fair values of the net assets acquired from Propel as of the acquisition date were determined to be $36.0 million of definite-lived intangible assets and $2.8 million of goodwill. We expect the goodwill recorded to be deductible for income tax purposes. The acquired analytical flow cytometer platform fits well into Bio-Rad’s existing Life Science segment product offerings and may offer researchers greater access to this technology.

In addition, Bio-Rad contracted with Propel to provide development services concurrent with and included in the purchase agreement. Bio-Rad is receiving future manufacturing, engineering and marketing support from Propel on which payments will be made upon the successful completion of all contracted services. As a result, these services are not included in the total purchase consideration and a majority will be expensed in future periods.

3.FAIR VALUE MEASUREMENTS

We determine the fair value of an asset or liability based on the assumptions that market participants would use in pricing the asset or liability in an orderly transaction between market participants at the measurement date.  The identification of market participant assumptions provides a basis for determining what inputs are to be used for pricing each asset or liability.  A fair value hierarchy has been established which gives precedence to fair value measurements calculated using observable inputs over those using unobservable inputs. This hierarchy prioritizes the inputs into three broad levels as follows:

• Level 1: Quoted prices in active markets for identical instruments

• Level 2: Other significant observable inputs (including quoted prices in active markets for similar instruments)

• Level 3: Significant unobservable inputs (including assumptions in determining the fair value of certain investments)

Financial assets and liabilities carried at fair value and measured on a recurring basis as of September 30, 2016 are classified in the hierarchy as follows (in millions):

11

	Level 1		Level 2		Level 3		Total
Financial Assets Carried at Fair Value:
Cash equivalents:
Commercial paper	$	—	$	11.6	$	—	$	11.6
Municipals	—		0.7		—		0.7
Foreign time deposits	10.3		—		—		10.3
Domestic time deposits	—		20.0		—		20.0
Money market funds	6.5		—		—		6.5
Total cash equivalents (a)	16.8		32.3		—		49.1
Restricted investment:	4.2		—		—		4.2
Available-for-sale investments:
Corporate debt securities	—		185.6		—		185.6
U.S. government sponsored agencies	—		76.8		—		76.8
Foreign government obligations	—		5.2		—		5.2
Brokered CD's	—		3.1		—		3.1
Municipal obligations	—		14.8		—		14.8
Marketable equity securities	844.5		—		—		844.5
Asset-backed securities	—		67.5		—		67.5
Total available-for-sale investments (b)	844.5		353.0		—		1,197.5
Forward foreign exchange contracts (c)	—		0.6		—		0.6
Total financial assets carried at fair value	$	865.5	$	385.9	$	—	$	1,251.4
Financial Liabilities Carried at Fair Value:
Forward foreign exchange contracts (d)	$	—	$	0.8	$	—	$	0.8
Contingent consideration (e)	—		—		42.7		42.7
Total financial liabilities carried at fair value	$	—	$	0.8	$	42.7	$	43.5

12

Financial assets and liabilities carried at fair value and measured on a recurring basis as of December 31, 2015 are classified in the hierarchy as follows (in millions):

	Level 1		Level 2		Level 3		Total
Financial Assets Carried at Fair Value:
Cash equivalents:
Commercial paper	$	—	$	33.2	$	—	$	33.2
Foreign government obligations	—		0.6		—		0.6
Foreign time deposits	11.9		—		—		11.9
U.S. government sponsored agencies	—		14.6		—		14.6
Money market funds	11.3		—		—		11.3
Total cash equivalents (a)	23.2		48.4		—		71.6
Restricted investment:	4.2		—		—		4.2
Available-for-sale investments:
Corporate debt securities	—		156.9		—		156.9
U.S. government sponsored agencies	—		74.8		—		74.8
Foreign government obligations	—		4.6		—		4.6
Municipal obligations	—		6.4		—		6.4
Marketable equity securities	660.1		—		—		660.1
Asset-backed securities	—		54.8		—		54.8
Total available-for-sale investments (b)	660.1		297.5		—		957.6
Forward foreign exchange contracts (c)	—		0.9		—		0.9
Total financial assets carried at fair value	$	687.5	$	346.8	$	—	$	1,034.3
Financial Liabilities Carried at Fair Value:
Forward foreign exchange contracts (d)	$	—	$	1.1	$	—	$	1.1
Contingent consideration (e)	—		—		19.1		19.1
Total financial liabilities carried at fair value	$	—	$	1.1	$	19.1	$	20.2

(a) Cash equivalents are included in Cash and cash equivalents in the Condensed Consolidated Balance Sheets.

(b) Available-for-sale investments are included in the following accounts in the Condensed Consolidated Balance Sheets (in millions):

	September 30, 2016		December 31, 2015
Short-term investments	$	388.2	$	328.7
Other investments	809.3		628.9
Total	$	1,197.5	$	957.6

(c) Forward foreign exchange contracts in an asset position are included in Other current assets in the Condensed Consolidated Balance Sheets.

(d) Forward foreign exchange contracts in a liability position are included in Other current liabilities in the Condensed Consolidated Balance Sheets.

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(e) Contingent consideration liability is included in the following accounts in the Condensed Consolidated Balance Sheets (in millions):

	September 30, 2016		December 31, 2015
Other current liabilities	$	13.4	$	13.5
Other long-term liabilities	29.3		5.6
Total	$	42.7	$	19.1

In 2012, we recognized a contingent consideration liability for certain milestones of $44.6 million upon our acquisition of a new cell sorting system from Propel. Since 2012, we have paid $28.9 million upon reaching the milestones and have reduced the valuation of the milestones by $12.3 million to its estimated fair value of $3.4 million as of September 30, 2016.

During the first quarter of 2016, we recognized a contingent consideration liability upon our acquisition of a new high performance analytical flow cytometer platform from Propel. At the acquisition date, the contingent consideration was based on a probability-weighted income approach related to the achievement of sales milestones, ranging from 39% to 20% for the calendar years 2017 through 2020. The sales milestones could potentially range from $0 to an unlimited amount through December 31, 2020. The contingent consideration was recognized at its estimated fair value of $29.3 million as of September 30, 2016.

The following table provides a reconciliation of the Level 3 cell sorting system and analytical flow cytometer platform contingent consideration liabilities measured at estimated fair value based on original valuations and updated quarterly for the nine months ended September 30, 2016 (in millions):

	2016
January 1	$	9.1
Cell sorting system:
Payment of sales milestone	(3.5		)
Decrease in estimated fair value of contingent consideration included in Selling, general and administrative expense	(2.2		)
Analytical flow cytometer platform:
Acquisition of high performance analytical flow cytometer platform	29.3
September 30	$	32.7

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The following table provides quantitative information about Level 3 inputs for fair value measurement of our cell sorting system and analytical flow cytometer platform contingent consideration liabilities as of September 30, 2016. Significant increases or decreases in these inputs in isolation could result in a significantly lower or higher fair value measurement.

			Range
	Valuation Technique	Unobservable Input	From		To
Cell sorting system	Probability-weighted income approach	Sales milestones:
		Credit adjusted discount rates	0.50%		N/A
		Projected volatility of growth rate	14%		N/A
		Market price of risk	1.30%		N/A
Analytical flow cytometer platform	Probability-weighted income approach	Sales milestones:
		Market price of risk	6	%
		Volatility	10	%

In 2014, we recognized a contingent consideration liability upon our acquisition of GnuBIO. The contingent consideration for the milestones was valued at $10.7 million at the acquisition date based on assumptions regarding the probability of achieving the milestones, with such amounts discounted to present value. The Level 3 contingent consideration was revalued to a fair value of $10.0 million as of September 30, 2016 and December 31, 2015.

To estimate the fair value of Level 2 debt securities as of September 30, 2016 and December 31, 2015, our primary pricing provider uses S&P Capital IQ as the primary pricing source. Our pricing process allows us to select a hierarchy of pricing sources for securities held. The chosen pricing hierarchy for our Level 2 securities, other than certificates of deposit and commercial paper, is S&P Capital IQ as the primary pricing source and then our custodian as the secondary pricing source. If S&P Capital IQ does not price a Level 2 security that we hold, then the pricing provider will utilize our custodian supplied pricing.

For commercial paper as of September 30, 2016 and December 31, 2015, pricing is determined by a straight-line calculation, starting with the purchase price on the date of purchase and increasing to par at maturity. Interest bearing certificates of deposit and commercial paper are priced at par.

Our pricing provider performs daily reasonableness testing of the S&P Capital IQ prices. Price changes of 5% or greater are investigated and resolved. In addition, we perform a quarterly testing of the S&P Capital IQ prices to custodian reported prices. Price differences outside a tolerable variance of approximately 1% are investigated and resolved.

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Available-for-sale investments consist of the following (in millions):

	September 30, 2016
	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
Short-term investments:
Corporate debt securities	$	184.7	$	1.0	$	(0.1	)	$	185.6
Brokered certificates of deposit	3.1		—		—			3.1
Municipal obligations	14.7		0.1		—			14.8
Asset-backed securities	67.1		0.2		(0.1		)	67.2
U.S. government sponsored agencies	76.2		0.7		(0.1		)	76.8
Foreign government obligations	5.2		—		—			5.2
Marketable equity securities	31.8		4.0		(0.3		)	35.5
	382.8		6.0		(0.6		)	388.2
Long-term investments:
Marketable equity securities	54.5		754.5		—			809.0
Asset-backed securities	0.3		—		—			0.3
	54.8		754.5		—			809.3
Total	$	437.6	$	760.5	$	(0.6	)	$	1,197.5

	December 31, 2015
	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
Short-term investments:
Corporate debt securities	$	157.2	$	0.1	$	(0.4	)	$	156.9
Municipal obligations	6.4		—		—			6.4
Asset-backed securities	54.8		—		(0.2		)	54.6
U.S. government sponsored agencies	74.9		0.1		(0.2		)	74.8
Foreign government obligations	4.6		—		—			4.6
Marketable equity securities	29.4		2.7		(0.7		)	31.4
	327.3		2.9		(1.5		)	328.7
Long-term investments:
Marketable equity securities	54.5		574.2		—			628.7
Asset-backed securities	0.3		—		(0.1		)	0.2
	54.8		574.2		(0.1		)	628.9
Total	$	382.1	$	577.1	$	(1.6	)	$	957.6

The unrealized gains of our long-term marketable equity securities are primarily due to our investment in Sartorius AG preferred shares.

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The following is a summary of investments with gross unrealized losses and the associated fair value (in millions):

	September 30, 2016		December 31, 2015
Fair value of investments in a loss position 12 months or more	$	13.2	$	10.4
Fair value of investments in a loss position less than 12 months	$	66.7	$	204.0
Gross unrealized losses for investments in a loss position 12 months or more	$	0.3	$	0.4
Gross unrealized losses for investments in a loss position less than 12 months	$	0.3	$	1.2

The unrealized losses on these securities are due to a number of factors, including changes in interest rates, changes in economic conditions and changes in market outlook for various industries, among others.  Because Bio-Rad has the ability and intent to hold these investments with unrealized losses until a recovery of fair value, or for a reasonable period of time sufficient for a forecasted recovery of fair value, which may be maturity, we do not consider these investments to be other-than-temporarily impaired at September 30, 2016 or at December 31, 2015.

As part of distributing our products, we regularly enter into intercompany transactions.  We enter into forward foreign exchange contracts to manage foreign exchange risk of future movements in foreign exchange rates that affect foreign currency denominated intercompany receivables and payables.  We do not use derivative financial instruments for speculative or trading purposes.  We do not seek hedge accounting treatment for these contracts.  As a result, these contracts, generally with maturity dates of 90 days or less and denominated primarily in currencies of industrial countries, are recorded at their fair value at each balance sheet date.  The notional principal amounts provide one measure of the transaction volume outstanding as of September 30, 2016 and do not represent the amount of Bio-Rad's exposure to loss. The estimated fair value of these contracts was derived using the spot rates from Reuters on the last business day of the quarter and the points provided by counterparties.  The resulting gains or losses offset exchange gains or losses on the related receivables and payables, both of which are included in Foreign currency exchange losses, net in the Condensed Consolidated Statements of Income.

The following is a summary of our forward foreign exchange contracts (in millions):

	September 30,
	2016
Contracts maturing in October through December 2016 to sell foreign currency:
Notional value	$	19.3
Unrealized gain	$	—
Contracts maturing in October through December 2016 to purchase foreign currency:
Notional value	$	344.9
Unrealized loss	$	(0.3	)

The following is a summary of the amortized cost and estimated fair value of our debt securities at September 30, 2016 by contractual maturity date (in millions):

	Amortized Cost		Estimated Fair Value
Mature in less than one year	$	142.4	$	142.5
Mature in one to five years	152.4		152.9
Mature in more than five years	56.5		57.6
Total	$	351.3	$	353.0

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The estimated fair value of financial instruments that are not recognized at fair value in the Condensed Consolidated Balance Sheets and are included in Other investments, are presented in the table below. Fair value has been determined using significant observable inputs, including quoted prices in active markets for similar instruments.  Estimates are not necessarily indicative of the amounts that could be realized in a current market exchange as considerable judgment is required in interpreting market data used to develop estimates of fair value. The use of different market assumptions or estimation techniques could have a material effect on the estimated fair value.  Other investments include financial instruments, the majority of which have fair value based on similar, actively traded stock adjusted for various discounts, including a discount for marketability.  Long-term debt, excluding leases and current maturities, has an estimated fair value based on quoted market prices for the same or similar issues.

The estimated fair value of the financial instruments discussed above and the level of the fair value hierarchy within which the fair value measurement is categorized are as follows (in millions):

	September 30, 2016					December 31, 2015
	Carrying  Amount		Estimated  Fair  Value		Fair Value Hierarchy Level	Carrying  Amount		Estimated  Fair  Value		Fair Value Hierarchy Level
Other investments	$	88.5	$	1,084.0	2	$	86.5	$	843.2	2
Total long-term debt, excluding leases and current maturities	$	422.3	$	465.1	2	$	421.9	$	454.3	2

We own shares of ordinary voting stock of Sartorius AG (Sartorius), of Goettingen, Germany, a process technology supplier to the biotechnology, pharmaceutical, chemical and food and beverage industries.  We own over 35% of the outstanding voting shares (excluding treasury shares) of Sartorius as of September 30, 2016.  The Sartorius family trust and Sartorius family members hold a controlling interest of the outstanding voting shares. We do not have any representative or designee on Sartorius’ Board of Directors, nor do we have the ability to exercise significant influence over the operating and financial policies of Sartorius.  We account for this investment using the cost method.  The carrying value of this investment is included in Other investments in our Condensed Consolidated Balance Sheets. As the stock is thinly traded and in conjunction with the valuation method discussed above, we have classified the estimated fair value as Level 2. The Level 2 classification is appropriate given the valuation method employed, which incorporates an observable input of the fair value of the Sartorius’ actively traded preferred stock.

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4.GOODWILL AND OTHER PURCHASED INTANGIBLE ASSETS

Changes to goodwill by segment were as follows (in millions):

	Life Science			Clinical Diagnostics			Total
Balances as of January 1, 2016:
Goodwill	$	207.2		$	316.9		$	524.1
Accumulated impairment losses	(27.2		)	(1.0		)	(28.2		)
Goodwill, net	180.0			315.9			495.9
Acquisitions	2.8			—			2.8
Currency fluctuations	0.4			7.5			7.9
Balances as of September 30, 2016:
Goodwill	210.4			324.4			534.8
Accumulated impairment losses	(27.2		)	(1.0		)	(28.2		)
Goodwill, net	$	183.2		$	323.4		$	506.6

In conjunction with the purchase of certain assets from Propel in January 2016 (see Note 2, "Acquisitions"), we recorded $2.8 million of goodwill and $36.0 million of definite-lived intangible assets: $33.0 million of developed product technology and $3.0 million of covenants not to compete.

Information regarding our identifiable purchased intangible assets with definite and indefinite lives is as follows (in millions):

	September 30, 2016
	Average Remaining Life (years)	Purchase Price		Accumulated Amortization			Net Carrying Amount
Customer relationships/lists	1-9	$	88.0	$	(53.4	)	$	34.6
Know how	1-9	186.8		(138.7		)	48.1
Developed product technology	3-13	131.9		(55.9		)	76.0
Licenses	2-10	39.5		(30.3		)	9.2
Tradenames	5-8	3.7		(2.7		)	1.0
Covenants not to compete	2-10	7.9		(2.3		)	5.6
Total definite-lived intangible assets		457.8		(283.3		)	174.5
In-process research and development		46.4		—			46.4
Total purchased intangible assets		$	504.2	$	(283.3	)	$	220.9

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	December 31, 2015
	Average Remaining Life (years)	Purchase Price		Accumulated Amortization			Net Carrying Amount
Customer relationships/lists	2-10	$	84.7	$	(46.8	)	$	37.9
Know how	1-10	184.0		(121.6		)	62.4
Developed product technology	4-12	101.3		(48.9		)	52.4
Licenses	3-10	39.2		(28.5		)	10.7
Tradenames	5-9	3.5		(2.4		)	1.1
Covenants not to compete	3-7	4.8		(1.7		)	3.1
Total definite-lived intangible assets		417.5		(249.9		)	167.6
In-process research and development		46.4		—			46.4
Total purchased intangible assets		$	463.9	$	(249.9	)	$	214.0

Amortization expense related to purchased intangible assets is as follows (in millions):

	Three Months Ended				Nine Months Ended
	September 30,				September 30,
	2016		2015		2016		2015
Amortization expense	$	9.5	$	9.2	$	28.5	$	27.7

5.PRODUCT WARRANTY LIABILITY

We warrant certain equipment against defects in design, materials and workmanship, generally for a period of one year.  Upon delivery of that equipment, we establish, as part of Cost of goods sold, a provision for the expected costs of such warranty based on historical experience, specific warranty terms and customer feedback.  A review is performed on a quarterly basis to assess the adequacy of our warranty accrual.

Components of the warranty accrual, included in Other current liabilities and Other long-term liabilities in the Condensed Consolidated Balance Sheets, were as follows (in millions):

January 1, 2016	$	17.4
Provision for warranty	22.0
Actual warranty costs	(21.8		)
September 30, 2016	$	17.6

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6.    LONG-TERM DEBT

The principal components of long-term debt are as follows (in millions):

	September 30, 2016			December 31, 2015
4.875% Senior Notes due 2020 principal amount	$	425.0		$	425.0
Less unamortized discount and debt issuance costs	(2.7		)	(3.1		)
Long-term debt less unamortized discount and debt issuance costs	422.3			421.9
Capital leases and other debt	12.1			12.3
	434.4			434.2
Less current maturities	(0.3		)	(0.3		)
Long-term debt	$	434.1		$	433.9

Senior Notes due 2020

In December 2010, Bio-Rad sold $425.0 million principal amount of Senior Notes due 2020 (4.875% Notes).  The sale yielded net cash proceeds of $422.6 million at an effective rate of 4.946%.  The 4.875% Notes pay a fixed rate of interest of 4.875% per year.  We have the option to redeem any or all of the 4.875% Notes at any time at a redemption price of 100% of the principal amount (plus a specified make-whole premium as defined in the indenture governing the 4.875% Notes) and accrued and unpaid interest thereon to the redemption date.  Our obligations under the 4.875% Notes are not secured and rank equal in right of payment with all of our existing and future unsubordinated indebtedness.  Certain covenants apply at each year end to the 4.875% Notes including limitations on the following: liens, sale and leaseback transactions, mergers, consolidations or sales of assets and other covenants. There are no restrictive covenants relating to total indebtedness, interest coverage, stock repurchases, recapitalizations, dividends and distributions to shareholders or current ratios.

Credit Agreement

In June 2014, Bio-Rad entered into a $200.0 million unsecured Credit Agreement, replacing the Amended and Restated Credit Agreement of June 2010, which expired on June 21, 2014. Borrowings under the Credit Agreement are on a revolving basis and can be used to make permitted acquisitions, for working capital and for other general corporate purposes. We had no outstanding borrowings under the Credit Agreement as of September 30, 2016 or December 31, 2015, however $0.8 million was utilized for domestic standby letters of credit that reduced our borrowing availability. The Credit Agreement matures in June 2019. If we had borrowed against our Credit Agreement, the borrowing rate would have been 2.10% at September 30, 2016.

The Credit Agreement requires Bio-Rad to comply with certain financial ratios and covenants, among other things. These ratios and covenants include a leverage ratio test and an interest coverage test, as well as restrictions on our ability to declare or pay dividends, incur debt, guarantee debt, enter into transactions with affiliates, merge or consolidate, sell assets, make investments and create liens.  We were in compliance with all of these ratios and covenants as of September 30, 2016.

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7.    ACCUMULATED OTHER COMPREHENSIVE INCOME

Accumulated other comprehensive income included in our Condensed Consolidated Balance Sheets consists of the following components (in millions):

	Foreign currency translation adjustments		Foreign other post-employment benefits adjustments			Net unrealized holding gains on available-for-sale investments			Total accumulated other comprehensive income
Balances as of January 1, 2016:	$	33.7	$	(20.7	)	$	369.1		$	382.1
Other comprehensive income (loss), before reclassifications	22.9		(0.7		)	184.8			207.0
Amounts reclassified from Accumulated other comprehensive income	—		0.9			(0.6		)	0.3
Income tax effects	—		(0.2		)	(67.8		)	(68.0		)
Other comprehensive income, net of income taxes	22.9		—			116.4			139.3
Balances as of September 30, 2016:	$	56.6	$	(20.7	)	$	485.5		$	521.4

	Foreign currency translation adjustments			Foreign other post-employment benefits adjustments			Net unrealized holding gains on available-for-sale investments			Total accumulated other comprehensive income
Balances as of January 1, 2015:	$	71.2		$	(16.3	)	$	164.0		$	218.9
Other comprehensive (loss) income, before reclassifications	(10.1		)	—			269.4			259.3
Amounts reclassified from Accumulated other comprehensive income	—			0.5			(0.4		)	0.1
Income tax effects	—			—			(99.0		)	(99.0		)
Other comprehensive (loss) income, net of income taxes	(10.1		)	0.5			170.0			160.4
Balances as of September 30, 2015:	$	61.1		$	(15.8	)	$	334.0		$	379.3

The amounts reclassified out of Accumulated other comprehensive income into the Condensed Consolidated Statements of Income, with presentation location, were as follows:

	Income before taxes impact (in millions):
		Three Months Ended						Nine Months Ended
		September 30,						September 30,
Components of Comprehensive income		2016			2015			2016			2015			Location
Amortization of foreign other post-employment benefit items		$	(0.3	)	$	(0.6	)	$	(0.9	)	$	(0.5	)	Selling, general and administrative expense
Net holding gains on available-for-sale investments		$	0.1		$	0.1		$	0.6		$	0.4		Other (income) expense, net

Reclassification adjustments are calculated using the specific identification method.

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8.    EARNINGS PER SHARE

Basic earnings per share is computed by dividing net income attributable to Bio-Rad by the weighted average number of common shares outstanding for that period.  Diluted earnings per share takes into account the effect of dilutive instruments, such as stock options and restricted stock, and uses the average share price for the period in determining the number of potential common shares that are to be added to the weighted average number of shares outstanding.  Potential common shares are excluded from the diluted earnings per share calculation if the effect of including such securities would be anti-dilutive.

The weighted average number of common shares outstanding used to calculate basic and diluted earnings per share, and the anti-dilutive shares that are excluded from the diluted earnings per share calculation are as follows (in thousands):

	Three Months Ended		Nine Months Ended
	September 30,		September 30,
	2016	2015	2016	2015
Basic weighted average shares outstanding	29,444	29,195	29,402	29,141
Effect of potentially dilutive stock options and restricted stock awards	227	244	190	231
Diluted weighted average common shares	29,671	29,439	29,592	29,372
Anti-dilutive shares	50	44	77	112

9.    OTHER INCOME AND EXPENSE, NET

Other (income) expense, net includes the following components (in millions):

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Interest and investment income	$	(1.3	)	$	(0.7	)	$	(13.2	)	$	(8.7	)
Net realized gain on investments	(0.1		)	—			(0.6		)	(0.3		)
Other (income) expense, net	$	(1.4	)	$	(0.7	)	$	(13.8	)	$	(9.0	)

10.    INCOME TAXES

Our effective income tax rate was 19% and 32% for the three months ended September 30, 2016 and 2015, respectively. Our effective income tax rate was 30% and 31% for the first nine months of 2016 and 2015, respectively. The effective tax rate for the third quarter and the first nine months of 2016 was lower primarily due to adjustments related to U.S. foreign tax credits. The effective tax rate for the first nine months of 2016 and 2015 included a tax benefit from the release of U.S. tax liabilities as a result of lapses of statutes of limitations.

Our foreign taxes result primarily from income earned in France and Switzerland. Many jurisdictions in which we operate including Switzerland, Russia, the U.K. and Singapore have statutory tax rates that are significantly lower than the U.S. statutory tax rate of 35%. Our effective tax rate may be impacted in the future, either favorably or unfavorably, by many factors including, but not limited to, changes to statutory tax rates, changes in tax laws or regulations, tax audits and settlements, and generation of tax credits.

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Our income tax returns are audited by U.S. federal, state and foreign tax authorities. We are currently under examination by many of these tax authorities. There are differing interpretations of tax laws and regulations, and as a result, significant disputes may arise with these tax authorities involving issues of the timing and amount of deductions and allocations of income among various tax jurisdictions. We evaluate our exposures associated with our tax filing positions on a quarterly basis.

We record liabilities for unrecognized tax benefits related to uncertain tax positions. We do not believe any currently pending uncertain tax positions will have a material adverse effect on our condensed consolidated financial statements, although an adverse resolution of one or more of these uncertain tax positions in any period may have a material impact on the results of operations for that period.

As of September 30, 2016, based on the expected outcome of certain examinations or as a result of the expiration of statutes of limitations for certain jurisdictions, we believe that within the next 12 months it is reasonably possible that our previously unrecognized tax benefits could decrease by approximately $3.1 million. Substantially all such amounts will impact our effective income tax rate.

11.    SEGMENT INFORMATION

Information regarding industry segments for the three months ended September 30, 2016 and 2015 is as follows (in millions):

		Life Science			Clinical Diagnostics		Other Operations
Segment net sales	2016	$	178.1		$	327.1	$	3.5
	2015	$	150.4		$	316.2	$	3.4
Segment net (loss) profit	2016	$	(4.4	)	$	28.4	$	0.3
	2015	$	(12.3	)	$	40.2	$	0.4

Information regarding industry segments for the nine months ended September 30, 2016 and 2015 is as follows (in millions):

		Life Science			Clinical Diagnostics		Other Operations
Segment net sales	2016	$	523.9		$	962.5	$	10.3
	2015	$	476.8		$	961.9	$	10.2
Segment net (loss) profit	2016	$	(12.9	)	$	77.0	$	0.5
	2015	$	(20.4	)	$	116.3	$	0.2

Segment results are presented in the same manner as we present our operations internally to make operating decisions and assess performance.  Net corporate operating, interest and other expense for segment results consists of receipts and expenditures that are not the primary responsibility of segment operating management and therefore are not allocated to the segments for performance assessment by our chief operating decision maker.  Interest expense is charged to segments based on the carrying amount of inventory and receivables employed by that segment.  See Note 13 for a discussion of restructuring costs. The following reconciles total segment profit to consolidated income before taxes (in millions):

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	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Total segment profit	$	24.3		$	28.3		$	64.6		$	96.1
Foreign currency exchange losses, net	(1.2		)	(2.2		)	(3.6		)	(8.9		)
Net corporate operating, interest and other expense not allocated to segments	(1.8		)	(1.4		)	(5.1		)	(4.6		)
Other income (expense), net	1.4			0.7			13.8			9.0
Consolidated income before income taxes	$	22.7		$	25.4		$	69.7		$	91.6

12.    LEGAL PROCEEDINGS

On January 23, 2015, the City of Riviera Beach General Employees’ Retirement System filed a shareholder derivative lawsuit in the Superior Court of California, Contra Costa County, against three of our current directors and one former director. We are also named as a nominal defendant. In the complaint, the plaintiff alleges that our directors breached their fiduciary duty of loyalty by failing to ensure that we had sufficient internal controls and systems for compliance with the Foreign Corrupt Practices Act ("FCPA"); that we failed to provide adequate training on the FCPA; and that based on these actions, the directors have been unjustly enriched. Purportedly seeking relief on our behalf, the plaintiff seeks an award of restitution and unspecified damages, costs and expenses (including attorneys’ fees). On April 23, 2015, we and the individual defendants filed a demurrer requesting dismissal of the complaint in this case. The demurrer was heard on August 6, 2015, and the Court granted the demurrer for failure to make a demand on our Board of Directors on August 17, 2015, but provided leave to amend. On September 4, 2015, the plaintiff filed an amended complaint and simultaneously served a litigation demand letter on our Board of Directors ("Board") via its counsel in this action. The letter demands that we investigate and bring appropriate legal action against certain individuals, including the defendants in the City of Riviera Beach case and six current and former employees. The plaintiff also moved for a temporary stay in the proceedings, purportedly to enable the Board to respond to the demand. The Board formed a Demand Review Committee to respond to the demand. On February 24, 2016, the Demand Review Committee reported to the Board that it had concluded its investigation and unanimously determined that it is not in the best interests of the Company and its stockholders to pursue litigation against any individuals named in the City of Riviera Beach’s litigation demand letter. On October 6, 2015, we and the individual defendants filed a second demurrer, seeking to dismiss the case for failure to make a timely pre-suit demand. The case was stayed pending mediation. The caption is City of Riviera Beach General Employees’ Retirement System v. Schwartz et al., Case No. C-15-00140. The lawsuit and demand letter are referred to collectively as the “California Action”.

On August 13, 2015 and August 18, 2015, respectively, each of International Brotherhood of Electrical Workers Local 38 Pension Fund and Wayne County Employees’ Retirement System filed a stockholder derivative complaint in the Delaware Court of Chancery against four of our current directors and one former director. We are named as a nominal defendant in the complaints. The complaints allege that the defendants failed to cause us to develop internal controls sufficient to ensure our compliance with the FCPA. The plaintiffs assert claims for breach of fiduciary duty and unjust enrichment and request an award of the damages we sustained as a result of the alleged violations, among other relief. The two lawsuits were consolidated on August 27, 2015.  The case was stayed pending mediation. The caption of the consolidated case is In re Bio-Rad Laboratories, Inc. Stockholder Litigation, Consol. C.A. No. 11387-VCN (Del. Ch.). The cases filed in the Delaware Court of Chancery, together with the California Action, are referred to collectively as the “Derivative Actions”.

On July 28, 2016, we signed a Term Sheet that summarizes the material terms of a proposed settlement of the Derivative Actions. The proposed settlement includes the dismissal with prejudice of all claims asserted in the Derivative Actions, an agreed-upon set of revised corporate procedures, and no monetary payment other than an

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award of attorneys’ fees and costs to the plaintiffs’ counsel. The proposed settlement is subject to review and approval by the Superior Court of California for Contra Costa County. We and the other defendants do not admit any liability or fault in connection with the proposed settlement.

On May 27, 2015, our former general counsel, Sanford S. Wadler, filed a lawsuit in the U.S. District Court, Northern District of California, against us and four of our current directors and one former director. The plaintiff’s suit alleges whistleblower retaliation in violation of the Sarbanes-Oxley Act and the Dodd-Frank Act for raising FCPA-related concerns. Mr. Wadler also alleges wrongful termination in violation of public policy, non-payment of wages and waiting time penalties in violation of the California Labor Code. The plaintiff seeks back pay, compensatory damages for lost wages, earnings, retirement benefits and other employee benefits, compensation for mental pain and anguish and emotional distress, waiting time penalties, punitive damages, litigation costs (including attorneys’ fees) and reinstatement of employment. We believe this lawsuit is without merit, and on July 28, 2015 we filed a motion to dismiss the plaintiff's complaint and specifically requested dismissal of the claims alleged against us under the Dodd-Frank Act and California Labor Code 1102.5 and the claims against the directors under the Sarbanes-Oxley Act and the Dodd-Frank Act. On October 23, 2015, the District Court granted our motion with respect to the alleged violations of the Sarbanes-Oxley Act against all the director defendants except Norman Schwartz with prejudice. The Court denied our motion to dismiss the claims under the Dodd-Frank Act as against both us and the director defendants. Discovery is taking place. The parties engaged in mediation of the case on April 19, 2016 and on September 14, 2016. The mediations did not result in a settlement. The trial is scheduled to commence on January 9, 2017.

We are also party to various other claims, legal actions and complaints arising in the ordinary course of business. We cannot at this time reasonably estimate a range of exposure, if any, of the potential liability with respect to these matters. While we do not believe, at this time, that any ultimate liability resulting from any of these other matters will have a material adverse effect on our results of operations, financial position or liquidity, we cannot give any assurance regarding the ultimate outcome of these other matters and their resolution could be material to our operating results for any particular period, depending on the level of income for the period.

13.    RESTRUCTURING COSTS

For the three and nine months ended September 30, 2016, we recorded $(0.2) million and $11.5 million, respectively, related to restructuring actions that include the elimination or relocation of various positions. These actions are generally intended to streamline and focus our efforts and more properly align our cost structure with projected future revenue streams.

The following table summarizes the activity of our restructuring reserves for severance, including a minimal amount of $38.8 thousand for the impact of foreign currency (in millions):

	Life Science			Clinical Diagnostics			Total
Balance at December 31, 2015	$	—		$	—		$	—
Charged to expense	4.1			7.6			$	11.7
Adjustment to expense	(0.1		)	(0.1		)	$	(0.2	)
Cash payments	(0.9		)	(1.8		)	(2.7		)
Balance at September 30, 2016	$	3.1		$	5.7		$	8.8

In May, 2016, management announced that it will take certain actions in our Europe geographic region designed to better align expenses to our revenue and gross margin profile and position us for improved operating performance. These actions, aligned with creation and evolution of our organization structure and coordinated with the implementation of our global single instance ERP platform, are expected to be incurred through 2019. As a result, we recorded approximately $(0.2) million and $11.5 million in restructuring charges related to severance and other

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employee benefits for the three and nine months ended September 30, 2016, respectively, of which $8.8 million is anticipated to be paid through 2019. The liability of $8.8 million as of September 30, 2016 encompassed a short-term liability of $5.8 million and a long-term liability of $3.0 million. The amounts recorded were reflected in Cost of goods sold of $0.2 million and $2.0 million, and in Selling, general and administrative expense of $(0.4) million and $9.5 million in the Condensed Consolidated Statements of Income for the three and nine months ended September 30, 2016, respectively. The amounts adjusted were primarily due to employees finding other positions within Bio-Rad or leaving prematurely.

Item 2. Management’s Discussion and Analysis of Financial Condition and Results of Operations

This discussion should be read in conjunction with the information contained in both our Consolidated Financial Statements for the year ended December 31, 2015 and the financial statements for the three and nine months ended September 30, 2016.

Overview.  We are a multinational manufacturer and worldwide distributor of our own life science research and clinical diagnostics products.  Our business is organized into two reportable segments, Life Science and Clinical Diagnostics, with the mission to provide scientists with specialized tools needed for biological research and clinical diagnostics.  

We sell more than 8,000 products and services to a diverse client base comprised of scientific research, healthcare, education and government customers worldwide. We do not disclose quantitative information about our different products and services as it is impractical to do so based primarily on the numerous products and services that we sell and the global markets that we serve.

We manufacture and supply our customers with a range of reagents, apparatus and equipment to separate complex chemical and biological materials and to identify, analyze and purify components.  Because our customers require standardization for their experiments and test results, much of our revenues are recurring.  

We are impacted by the support of many governments for both research and healthcare. The current global economic outlook is still uncertain as the need to control government social spending by many governments limits opportunities for growth. Adding to this uncertainty was the recent referendum in the United Kingdom to withdraw from the European Union. Approximately 39% of our year-to-date 2016 consolidated net sales are derived from the United States and approximately 61% are derived from international locations, with Europe being our largest international region.  The international sales are largely denominated in local currencies such as the Euro, Swiss Franc, Japanese Yen, Chinese Yuan and British Sterling.  As a result, our consolidated net sales expressed in dollars benefit when the U.S. dollar weakens and suffer when the dollar strengthens.  When the U.S. dollar strengthens, we benefit from lower cost of sales from our own international manufacturing sites as well as non-U.S. suppliers, and from lower international operating expenses. We regularly discuss our changes in revenue and expense categories in terms of both changing foreign exchange rates and in terms of a currency neutral basis, if notable, to explain the impact currency has on our results.

In May 2016, we announced the elimination or relocation of various positions as part of restructuring plans approved by management. In connection with this announcement, for the three and nine months ended September 30, 2016, we recorded approximately $(0.2) million and $11.5 million, respectively, in restructuring charges related to severance and other employee benefits, of which $8.8 million is anticipated to be paid through 2019. These restructuring actions are primarily intended to reduce, eliminate or relocate our global workforce in order to better align expenses to our revenue and gross margin profile and position us for improved operating performance. These actions are aligned with the creation and evolution of our organization structure and coordinated with the implementation of our single instance ERP platform. In the future, we may take additional restructuring actions to gain operating efficiencies or reduce our operating expenses, while simultaneously implementing additional cost containment measures and expense control programs. Such restructuring actions are subject to significant risks, including delays in implementing expense control programs or workforce reductions and

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the failure to meet operational targets due to the loss of employees or a decrease in employee morale, all of which would impair our ability to achieve anticipated cost reductions. If we do not achieve the anticipated cost reductions, our business could be harmed.

In January 2016, we acquired a high performance analytical flow cytometer platform from Propel Labs (Propel) that will enable advanced and novice users to perform basic and multi-parameter cytometry for a wide range of applications and chemistries. This asset acquisition was accounted for as a business combination and is included in our Life Science segment's results of operations from the acquisition date. The final fair values of the net assets acquired from Propel as of the acquisition date were determined to be $36.0 million of definite-lived intangible assets and $2.8 million of goodwill.

The final fair value of the consideration as of the acquisition date was $38.8 million, which included $9.5 million paid in cash at the closing date and $29.3 million in contingent consideration potentially payable to Propel. The contingent consideration was based on a probability-weighted income approach related to the achievement of sales milestones, ranging from 39% to 20% for the calendar years 2017 through 2020. The sales milestones could potentially range from $0 to an unlimited amount through December 31, 2020. The contingent consideration was recognized at its estimated fair value of $29.3 million as of September 30, 2016.

In 2014, we recognized a contingent consideration liability upon our acquisition of GnuBIO. The contingent consideration for the milestones was valued at $10.7 million at the acquisition date based on assumptions regarding the probability of achieving the milestones, with such amounts discounted to present value. The Level 3 contingent consideration was revalued to a fair value of $10.0 million as of September 30, 2016 and December 31, 2015.

In 2012, we recognized a contingent consideration liability for certain milestones of $44.6 million upon our acquisition of a new cell sorting system from Propel. Since 2012, we have paid $28.9 million upon reaching the milestones and have reduced the valuation of the milestones by $12.3 million to its estimated fair value of $3.4 million as of September 30, 2016.

The following shows cost of goods sold, gross profit, expense items and net income as a percentage of net sales:

	Three Months Ended				Nine Months Ended
	September 30,				September 30,
	2016		2015		2016		2015
Net sales	100.0	%	100.0	%	100.0	%	100.0	%
Cost of goods sold	45.1		43.9		45.0		43.9
Gross profit	54.9		56.1		55.0		56.1
Selling, general and administrative expense	39.6		39.9		39.9		39.3
Research and development expense	9.8		9.2		10.1		9.5
Net income	3.6		3.7		3.3		4.4

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Critical Accounting Policies and Estimates

As previously disclosed in our Annual Report on Form 10-K for the year ended December 31, 2015, we have identified accounting for income taxes, valuation of goodwill and long-lived assets, valuation of inventories, warranty reserves, valuation of investments, allowance for doubtful accounts and litigation accruals as the accounting policies and estimates critical to the operations of Bio-Rad.

An accounting policy is deemed to be critical if it requires an accounting estimate to be made based on assumptions about matters that are highly uncertain at the time the estimate is made, if different estimates reasonably could have been used, or if changes in the estimate that are reasonably likely to occur could materially impact the financial statements.  Management believes that there have been no significant changes during the three and nine months ended September 30, 2016 to the items that we disclosed as our critical accounting policies and estimates in Management's Discussion and Analysis of Financial Condition and Results of Operations in our Annual Report on Form 10-K for the fiscal year ended December 31, 2015.  For a full discussion of these policies and estimates, please refer to our Form 10-K for the period ended December 31, 2015 filed with the SEC.

Three Months Ended September 30, 2016 Compared to

Three Months Ended September 30, 2015

Results of Operations -- Sales, Margins and Expenses

Net sales (sales) for the third quarter of 2016 were $508.7 million compared to $470.0 million in the third quarter of 2015, an increase of 8.3%.  Excluding the negative impact of foreign currency, third quarter 2016 sales increased by approximately 9.1% compared to the same period in 2015.  Currency neutral sales increased primarily in North America, Asia Pacific, excluding Japan, and Eastern Europe.

The Life Science segment sales for the third quarter of 2016 were $178.1 million, an increase of 18.4% compared to the same period last year.  On a currency neutral basis, sales increased 19.3% compared to the third quarter in 2015. The currency neutral sales increase was primarily in our Droplet Digital™ PCR and process media products. Sales were also higher as the third quarter of 2015 had delays in production and shipping due to integration issues associated with the implementation of the second phase of the global single instance enterprise resource planning (ERP) platform in July 2015. The currency neutral sales increase was reflected in all regions.

The Clinical Diagnostics segment sales for the third quarter of 2016 were $327.1 million, an increase of 3.5% compared to the same period last year.  On a currency neutral basis, sales increased 4.4% compared to the third quarter in 2015.  The currency neutral sales increase was primarily attributable to growth in diabetes, immunology, and quality control product lines. In anticipation of the implementation of the second phase of the global single instance ERP platform in July 2015, some sales deliveries occurred in the second quarter of 2015 rather than in the third quarter of 2015. On a geographic view, currency neutral sales for the quarter were up in North America and Asia Pacific, excluding Japan, and were down in Western Europe.

Consolidated gross margins were 54.9% for the third quarter of 2016 compared to 56.1% for the third quarter of 2015.  Life Science segment gross margins for the third quarter of 2016 increased from the prior year period by approximately 1.2 percentage points primarily due to higher margins in gene expression, protein quantification and antibody products, partially offset by lower margins in protein purification and higher acquisition intangible amortization in 2016. Clinical Diagnostics segment gross margins for the third quarter of 2016 decreased by approximately 1.9 percentage points from the same period last year. The decrease compared to the third quarter of 2015 was primarily driven by product mix, higher manufacturing costs and pricing pressures, partially offset by the suspension of the medical device tax in the United States.

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Beginning in 2013, the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act (PPACA), among other initiatives, provided for a 2.3% annual excise tax on the sales of certain medical devices in the U.S. Bio-Rad has been paying this excise tax on most of our U.S. Clinical Diagnostic sales, which we accounted for as a period cost in Cost of goods sold. However, the Consolidated Appropriations Act, 2016 (Pub. L. 114-113), signed into law on December 18, 2015, includes a two year moratorium on the medical device excise tax during the period beginning on January 1, 2016, and ending on December 31, 2017.

Selling, general and administrative expenses (SG&A) increased to $201.5 million or 39.6% of sales for the third quarter of 2016 compared to $187.4 million or 39.9% of sales for the third quarter of 2015.  Increases to SG&A primarily included $5.0 million for various legal matters, including the termination of several distributors, professional fees, and employee-related expenses. Decreases to SG&A primarily included facilities and bad debt expense.

Research and development expense (R&D) increased to $49.9 million or 9.8% of sales in the third quarter of 2016 compared to $43.3 million or 9.2% of sales in the third quarter of 2015.  Life Science segment R&D increased in the third quarter of 2016 from the prior year period primarily due to increased project activities in Droplet Digital™ PCR, protein quantification and cell biology. Clinical Diagnostics segment R&D increased in the third quarter of 2016 from the prior year period primarily from increased spending associated with the GnuBIO business.

Results of Operations – Non-operating

Interest expense for the third quarter of 2016 decreased to $5.6 million compared to $5.8 million for the third quarter of 2015 primarily due to higher capitalization of interest expense associated with the implementation of the current phase (D3) of our global single instance ERP platform. The capitalization of interest for the prior phase (D2) of our global single instance ERP platform was implemented in July of 2015 and therefore minimal interest was capitalized for D2.

Foreign currency exchange gains and losses consist primarily of foreign currency transaction gains and losses on intercompany net receivables and payables and the change in fair value of our forward foreign exchange contracts used to manage our foreign currency exchange risk.  Foreign currency exchange losses, net for the quarter ended September 30, 2016 decreased compared to the prior year period primarily due to the lower cost of hedging, the timing of product shipments and intercompany debt payments, and our decision to reclassify a large percentage of our intercompany receivable from Brazil as long-term.

Other (income) expense, net for the third quarter of 2016 increased to $1.4 million income compared to $0.7 million income for the third quarter of 2015 primarily due to higher investment income in 2016.

Our effective income tax rate was 19% and 32% for the three months ended September 30, 2016 and 2015, respectively. The effective tax rate for the third quarter of 2016 was lower primarily due to adjustments related to U.S. foreign tax credits.

Our foreign taxes result primarily from income earned in France and Switzerland. Many jurisdictions in which we operate including Switzerland, Russia, the U.K. and Singapore have statutory tax rates that are significantly lower than the U.S. statutory tax rate of 35%. Our effective tax rate may be impacted in the future, either favorably or unfavorably, by many factors including, but not limited to, changes to statutory tax rates, changes in tax laws or regulations, tax audits and settlements, and generation of tax credits.

Our income tax returns are audited by U.S. federal, state and foreign tax authorities. We are currently under examination by many of these tax authorities. There are differing interpretations of tax laws and regulations, and as a result, significant disputes may arise with these tax authorities involving issues of the timing and amount of deductions and allocations of income among various tax jurisdictions. We evaluate our exposures associated with our tax filing positions on a quarterly basis.

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We record liabilities for unrecognized tax benefits related to uncertain tax positions. We do not believe any currently pending uncertain tax positions will have a material adverse effect on our condensed consolidated financial statements, although an adverse resolution of one or more of these uncertain tax positions in any period may have a material impact on the results of operations for that period.

As of September 30, 2016, based on the expected outcome of certain examinations or as a result of the expiration of statutes of limitations for certain jurisdictions, we believe that within the next 12 months it is reasonably possible that our previously unrecognized tax benefits could decrease by approximately $3.1 million. Substantially all such amounts will impact our effective income tax rate.

Nine Months Ended September 30, 2016 Compared to

Nine Months Ended September 30, 2015

Results of Operations -- Sales, Margins and Expenses

Net sales (sales) for the first nine months of 2016 were $1.50 billion compared to $1.45 billion in the first nine months of 2015, an increase of 3.3%.  Excluding the impact of foreign currency, the first nine months of 2016 sales increased by approximately 5.2% compared to the same period in 2015.  Currency neutral sales increased primarily in North America, Asia Pacific including Japan, Latin America and Eastern Europe.

The Life Science segment sales for the first nine months of 2016 were $523.9 million, an increase of 9.9% compared to the same period last year.  On a currency neutral basis, sales increased 11.4% compared to the first nine months in 2015. The currency neutral sales increase was primarily in our Droplet Digital™ PCR and process media products. The currency neutral sales increase was in all regions, except Japan.

The Clinical Diagnostics segment sales for the first nine months of 2016 were $962.5 million, an increase of 0.1% compared to the same period last year.  On a currency neutral basis, sales increased 2.2% compared to the first nine months in 2015. The currency neutral sales increase was primarily attributable to growth in quality control, immunology and blood typing product lines. On a geographic view, currency neutral sales for the first nine months of 2016 increased most notably in the Americas and Asia, while sales declined in Europe.

Consolidated gross margins were 55.0% for the first nine months of 2016 compared to 56.1% for the first nine months of 2015.  Life Science segment gross margins for the first nine months of 2016 decreased from the prior year period by approximately 0.5 percentage points primarily due to lower margins in protein quantification, cell biology, higher service costs, higher acquisition intangible amortization, and $0.7 million for restructuring costs, partially offset by higher margins in Droplet Digital™ PCR, process media products and antibody products.

Clinical Diagnostics segment gross margins for the first nine months of 2016 decreased by approximately 1.3 percentage points from the same period last year. The decrease compared to the first nine months of 2015 was primarily driven by sales mix and pricing pressures, along with higher manufacturing costs, and $1.3 million in restructuring costs, partially offset by the suspension of the medical device tax in the United States.

SG&A increased to $596.7 million or 39.9% of sales for the first nine months of 2016 compared to $568.8 million or 39.3% of sales for the first nine months of 2015.  Increases to SG&A primarily included employee-related expenses, our largest cost, which also included $9.5 million for restructuring costs, $10.1 million for various legal matters, including the termination of several distributors, professional fees, software, facilities and travel. Decreases to SG&A primarily included bad debt expense, a one-time distributor cost in 2015 and the revaluation of contingent consideration associated with the cell sorting system.

R&D increased to $150.7 million or 10.1% of sales in the first nine months of 2016 compared to $137.1 million or 9.5% of sales in the first nine months of 2015.  Life Science segment R&D increased in the first nine months of 2016 from the prior year period primarily due to increased project activities in Droplet Digital™ PCR, protein quantification and cell biology. Clinical Diagnostics segment R&D increased in the first nine months of 2016 from

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the prior year period primarily from increased spending associated with the GnuBIO business and includes a $2.4 million write-off of intellectual property associated with the termination of a research and development project.

Results of Operations – Non-operating

Interest expense for the first nine months of 2016 increased to $16.8 million compared to $15.7 million for the first nine months of 2015 primarily due to lower capitalization of interest expense associated with the implementation of the current phase (D3) of our global single instance ERP platform. D3 was just beginning in 2016 and the prior phase (D2) of our global single instance ERP platform was implemented in July of 2015 and therefore on a year-to-date basis interest capitalized was higher for D2 in 2015.

Foreign currency exchange losses, net for the first nine months 2016 decreased compared to the prior year period primarily due to the lower cost of hedging, the timing of product shipments and intercompany debt payments, and our decision to reclassify a large percentage of our intercompany receivable from Brazil as long-term.

Other (income) expense, net for the first nine months of 2016 increased to $13.8 million income compared to $9.0 million income for the first nine months of 2015 primarily due to higher dividend income in 2016 on the ordinary and preferred shares of our investment in Sartorius AG, and higher investment income.

Our effective income tax rate was 30% and 31% for the first nine months of 2016 and 2015, respectively. The effective tax rate for the first nine months of 2016 was lower primarily due to adjustments related to U.S. foreign tax credits. The effective tax rate for the first nine months of 2016 and 2015 included a tax benefit from the release of U.S. tax liabilities as a result of lapses of statutes of limitations.

Our foreign taxes result primarily from income earned in France and Switzerland. Many jurisdictions in which we operate including Switzerland, Russia, the U.K. and Singapore have statutory tax rates that are significantly lower than the U.S. statutory tax rate of 35%. Our effective tax rate may be impacted in the future, either favorably or unfavorably, by many factors including, but not limited to, changes to statutory tax rates, changes in tax laws or regulations, tax audits and settlements, and generation of tax credits.

Liquidity and Capital Resources

Bio-Rad operates and conducts business globally, primarily through subsidiary companies established in the markets in which we trade.  Goods are manufactured in a small number of locations, and are then shipped to local distribution facilities around the world.  Our product mix is diversified, and certain products compete largely on product efficacy, while others compete on price.  Gross margins are generally sufficient to exceed normal operating costs, and funding for research and development of new products, as well as routine outflows of capital expenditures, interest and taxes.  In addition to the annual positive cash flow from operating activities, additional liquidity is readily available via the sale of short-term investments and access to our domestic $200.0 million unsecured Credit Agreement that we entered into in June 2014.  Borrowings under the Credit Agreement are on a revolving basis and can be used to make permitted acquisitions, for working capital and for other general corporate purposes. We had no outstanding borrowings under the Credit Agreement as of September 30, 2016, however $0.8 million was utilized for domestic standby letters of credit that reduced our borrowing availability.  The Credit Agreement matures in June 2019.

At September 30, 2016, we had $806.1 million in cash, cash equivalents and short-term investments, of which approximately 37% was held in our foreign subsidiaries. We believe that our holdings of cash, cash equivalents and short-term investments in the U.S. and in our foreign subsidiaries are sufficient to meet both the current and long-term needs of our global operations. The amount of funds held in the United States can fluctuate due to the timing of receipts and payments in the ordinary course of business and due to other reasons, such as business-development activities. As part of our ongoing liquidity assessments, we regularly monitor the mix of domestic and foreign cash flows (both inflows and outflows). Repatriation of overseas funds will result in additional U.S. federal and state

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income tax payments. In general, it is our practice and intention to indefinitely reinvest the cash generated by our foreign subsidiaries in our foreign subsidiaries' operations.

Under domestic and international lines of credit, standby letters of credit and guarantee arrangements, we had approximately $206.4 million available for borrowing and usage as of September 30, 2016, which was reduced by approximately $4.3 million that was utilized for standby letters of credit and guarantee arrangements issued by our banks to support our obligations. Management believes that this availability, together with cash flow from operations, will be adequate to meet our current objectives for operations, research and development, capital additions for manufacturing and distribution, plant and equipment, information technology systems and an acquisition of reasonable proportion to our existing total available capital.

While economic growth is somewhat improving, instability still exists in developed nations and in the U.S., such as the slowing rate of growth in the Chinese economy and in emerging markets, especially those oil producing countries that have been affected by a decline in oil prices, which may adversely affect our future cash flows. Demand for our products and services could change more dramatically than in previous years based on activity, funding, reimbursement constraints and support levels from government, universities, hospitals and private industry, including diagnostic laboratories.  The need for certain sovereign nations with large annual deficits to curtail spending could lead to slower growth of, or even a decline in, our business. Sovereign nations either delaying payment for goods and services or renegotiating their debts could impact our liquidity. The situation in these sovereign nations is continuously evolving and we have no greater knowledge of the situation other than what is publicly reported. As of September 30, 2016 and December 31, 2015, we had accounts receivable, net of an allowance for doubtful accounts, in Spain, Italy, Greece and Portugal of $38.1 million and $40.7 million, respectively.

Cash Flows from Operations

Net cash provided by operations was $121.3 million compared to $150.3 million for the nine months ended September 30, 2016 and 2015, respectively.  The decrease in cash flows was primarily the net effect of:

• more cash paid to suppliers and employees primarily related to higher payments to inventory suppliers as payments were delayed in the latter part of 2015 mostly associated with the second deployment of the ERP system, higher annual performance-based compensation payments in 2016, and higher legal and other professional fees,

• net payments in 2016 compared to net cash received in 2015 for forward foreign exchange contracts, and

• higher federal income tax payments in 2016 and lower income tax refunds received than in 2015, partially offset by

• higher cash received from customers primarily due to delays in the latter part of 2015 mostly associated with the second deployment of the ERP system, and

• higher investment income received.

Cash Flows from Investing Activities

Net cash used in investing activities was $163.8 million compared to $83.1 million for the nine months ended September 30, 2016 and 2015, respectively. Purchases, sales and maturities of marketable securities and investments combined had an overall decrease of $61.8 million primarily due to increases in purchases and less maturities, slightly offset by an increase in security sales. The increase of payments for acquisition and long-term investment was primarily due to the acquisition of a high performance analytical flow cytometer platform from Propel in January 2016. Capital expenditures were higher for the nine months ended September 30, 2016 compared to the same period last year, reflecting the implementation of the third phase of the ERP system.

Our investment objective is to maintain liquidity to meet anticipated operational and other corporate requirements in which capital is preserved and increased through investing in low risk, high quality securities with commensurate returns, consistent with our risk tolerance level.

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We continue to review possible acquisitions to expand both our Life Science and Clinical Diagnostics segments. We routinely meet with the principals or brokers of the subject companies.  We are currently in discussion and assessing a few possible acquisitions in which we expect our current reported cash and cash equivalents to be sufficient for any cash consideration for these possible acquisitions. However, it is not certain at this time that any of these discussions involving material or significant acquisitions will advance to completion.

Capital expenditures totaled $96.3 million and $84.0 million for the nine months ended September 30, 2016 and 2015, respectively.  Capital expenditures represent the addition and replacement of production machinery and research equipment, ongoing manufacturing and facility additions for expansion, regulatory, environmental and compliance. Also included in capital expenditures are investments in business systems and data communication upgrades and enhancements.  All periods include equipment placed with Clinical Diagnostics segment customers who then contract to purchase our reagents for use. As we continue to implement the latest phase of the ERP platform and expand our e-commerce platform, we expect capital expenditures to continue to remain historically higher for approximately the next three years. The current estimated future project cost for global implementation for the single instance ERP platform is projected to be $155 million and is estimated to take approximately three years to fully implement.

Cash Flows from Financing Activities

Net cash provided by financing activities was $6.2 million compared to $4.9 million for the nine months ended September 30, 2016 and 2015, respectively. This increase for the nine months ended September 30, 2016 was primarily due to an increase in proceeds from the issuance of common stock, partially offset by a decrease in excess tax benefits on share-based compensation.

We have outstanding Senior Notes of $425 million, which are not due until 2020. We believe the current cash is sufficient to meet normal operating costs, and funding for research and development of new products, as well as routine outflows of capital expenditures, interest and taxes.

The Board of Directors has authorized the repurchase of up to $18.0 million of Bio-Rad's common stock, of which $3.3 million has yet to be repurchased as of September 30, 2016. The Credit Agreement may limit our ability to repurchase our stock. In accordance with the terms of awards under the 2007 Incentive Award Plan, in June 2012, we withheld 122 shares of our Class A common stock and 917 shares of our Class B common stock to satisfy tax obligations due upon the vesting of restricted stock of certain of our employees, which is considered a repurchase of our stock. All of the restricted stock vested as of December 31, 2013 and therefore we do not anticipate any repurchasing of shares for this purpose. We had no other repurchases of our stock during the first nine months of 2016 or 2015.

Recent Accounting Standards Updates

In October 2016, Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update No. (“ASU”) 2016-16, "Intra-Entity Transfers of Assets Other Than Inventory." ASU 2016-16 requires immediate recognition of income tax consequences of intercompany asset transfers, other than inventory transfers.  Existing GAAP prohibits recognition of income tax consequences of intercompany asset transfers whereby the seller defers any net tax effect and the buyer is prohibited from recognizing a deferred tax asset on the difference between the newly created tax basis of the asset in its tax jurisdiction and its financial statement carrying amount as reported in the consolidated financial statements.  ASU 2016-16 specifically excludes from its scope intercompany inventory transfers whereby the recognition of tax consequences will take place when the inventory is sold to third parties. ASU 2016-16 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted as of the beginning of an annual reporting period for which financial statements have not been issued or made available for issuance. We are currently evaluating the effect ASU 2016-16 will have on our consolidated financial statements.

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In August 2016, FASB issued ASU 2016-15, "Classification of Certain Cash Receipts and Cash Payments." ASU 2016-15 is intended to reduce diversity in practice in how certain transactions are classified in the statement of cash flows. ASU 2016-15 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years, with early adoption permitted. We are currently evaluating the effect ASU 2016-15 will have on our consolidated statements of cash flows.

In June 2016, the FASB issued ASU 2016-13, "Measurement of Credit Losses on Financial Instruments." ASU 2016-13 will replace the current incurred loss approach with an expected loss model for instruments measured at amortized cost and require entities to record allowances for available-for-sale debt securities rather than reduce the carrying amount under the current other-than-temporary impairment model. ASU 2016-13 is effective for fiscal years beginning after December 15, 2019, and interim periods within those fiscal years. Early adoption is permitted for all entities for annual periods beginning after December 15, 2018, and interim periods therein. We are currently evaluating the effect ASU 2016-13 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-09, "Improvements to Employee Share-Based Payment Accounting." ASU 2016-09 will require all income tax effects of awards to be recognized in the income statement when the awards vest or are settled. It also will allow an employer to repurchase more of an employee’s shares than it can today for tax withholding purposes without triggering liability accounting and to make a policy election to account for forfeitures as they occur. ASU 2016-09 is effective for fiscal years beginning after December 15, 2016, and interim periods within those fiscal years and early adoption is permitted. We are currently evaluating the effect ASU 2016-09 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-07, "Simplifying the Transition to the Equity Method of Accounting," which eliminates the requirement to retrospectively apply the equity method in previous periods when an investor initially obtains significant influence over an investee. Under current guidance, an investor that doesn’t consolidate an investment and initially accounts for it under a method other than the equity method is required to retrospectively apply the equity method in prior periods in which it held the investment when it subsequently obtained significant influence. ASU 2016-07 will be applied on a prospective basis and is effective for all entities for fiscal years beginning after December 15, 2016, and interim periods within those years and early adoption is permitted. We do not plan to early adopt ASU 2016-07 and currently do not expect it to affect our consolidated financial statements when adopted on January 1, 2017.

In February 2016, the FASB issued ASU 2016-02, "Leases," which will require, among other items, lessees to recognize most leases as assets and liabilities on the balance sheet. Qualitative and quantitative disclosures will be enhanced to better understand the amount, timing and uncertainty of cash flows arising from leases. ASU 2016-02 is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years, with early adoption permitted. We do not plan to early adopt. ASU 2016-02 will be adopted on a modified retrospective basis, with elective reliefs, which requires application of ASU 2016-02 for all periods presented. We are currently evaluating the effect ASU 2016-02 will have on our consolidated financial statements.

In January 2016, the FASB issued ASU 2016-01, "Recognition and Measurement of Financial Assets and Financial Liabilities." Amendments under ASU 2016-01, among other items, require that all equity investments in unconsolidated entities (other than those accounted for using the equity method of accounting) will generally be measured at fair value through earnings. There will no longer be an available-for-sale classification, for which changes in fair value are reported in other comprehensive income, for equity securities with readily determinable fair values. For equity investments without readily determinable fair values, the cost method is also eliminated. However, entities will be able to elect to record equity investments without readily determinable fair values at cost, less impairment, and plus or minus subsequent adjustments for observable price changes. Changes in the basis of these equity investments will be reported in current earnings. ASU 2016-01 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. We are currently evaluating the effect ASU 2016-01 will have, if any, on our consolidated financial statements.

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In September 2015, the FASB issued ASU 2015-16, "Simplifying the Accounting for Measurement-Period Adjustments," which eliminates the requirement for an acquirer in a business combination to account for measurement-period adjustments retrospectively. Under ASU 2015-16, acquirers must recognize measurement-period adjustments during the period in which they determine the amounts, including the effect on earnings of any amounts they would have recorded in previous periods if the accounting had been completed at the acquisition date. The measurement period cannot exceed one year from the date of the acquisition. ASU 2015-16 was effective on January 1, 2016, and we adopted it at the same time as a change in accounting policy, which had no impact on our consolidated financial statements.

In July 2015, the FASB issued ASU 2015-11, “Simplifying the Measurement of Inventory.” Under current guidance, an entity subsequently measures inventory at the lower of cost or market, with market defined as replacement cost, net realizable value (NRV), or NRV less a normal profit margin. An entity uses current replacement cost provided that it is not above NRV (i.e., the ceiling) or below NRV less an “approximately normal profit margin” (i.e., the floor). ASU 2015-11 eliminates this analysis and requires entities to measure most inventory “at the lower of cost and NRV.” ASU 2015-11 is effective prospectively for annual periods beginning after December 15, 2016, and interim periods therein, with early adoption permitted. We will not early adopt. We do not expect ASU 2015-11 to have a material impact to our consolidated financial statements when adopted on January 1, 2017.

In April 2015, the FASB issued ASU 2015-03, "Simplifying the Presentation of Debt Issuance Costs." ASU 2015-03 was issued to simplify the presentation of debt issuance costs by requiring debt issuance costs to be presented as a deduction from the corresponding debt liability. This makes the presentation of debt issuance costs consistent with the presentation of debt discounts or premiums. Under prior U.S. GAAP, debt issuance costs were reported on the balance sheet as assets and amortized as interest expense. Under ASU 2015-03, debt issuance costs will continue to be amortized to interest expense using the effective interest method. In August 2015, the FASB issued ASU 2015-15, "Presentation and Subsequent Measurement of Debt Issuance Costs Associated with Line-of-Credit Arrangements" to clarify the SEC staff’s position that it would not object to an entity deferring and presenting debt issuance costs as an asset and subsequently amortizing the deferred debt issuance costs ratably over the term of the line-of-credit arrangement, which is our current practice. We adopted ASU 2015-03 on January 1, 2016 on a retrospective basis as a change in accounting policy. The Condensed Consolidated Balance Sheet as of December 31, 2015, was retrospectively adjusted by decreasing Other assets and Long-term debt, net of current maturities by $1.8 million, respectively.

In May 2014, the FASB issued ASU 2014-09, “Revenue from Contracts with Customers,” which requires an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. ASU 2014-09 will replace most existing revenue recognition guidance in GAAP when it becomes effective. In August 2015, the FASB issued ASU 2015-14 to defer the effective date for annual reporting periods beginning after December 15, 2017, including interim periods within that reporting period. Early adoption is permitted as of the original effective date in ASU 2014-09, which is annual reporting periods beginning after December 15, 2016, however, we will not early adopt. In May 2016, the FASB issued ASU 2016-12, "Narrow-Scope Improvements and Practical Expedients," which amends and clarifies certain aspects in ASU 2014-09 that include collectiblity, presentation of sales and other taxes collected from customers, noncash consideration, contract modifications and completed contracts at transition. In April 2016, the FASB issued ASU 2016-10, "Identifying Performance Obligations and Licensing," which amends the guidance in ASU 2014-09 on accounting for licenses of intellectual property and identifying performance obligations. In March 2016, The FASB issued ASU 2016-08, "Principal versus Agent Considerations (Reporting Revenue Gross versus Net)," which amends the principal versus agent guidance in ASU 2014-09. The standards are to be applied retrospectively and permit the use of either the retrospective or cumulative effect transition method. We will use the cumulative effect transition method once we adopt ASUs 2014-09, 2016-12, 2016-10 and 2016-08 on January 1, 2018. We are currently evaluating the effect that these ASUs will have on our consolidated financial statements and related disclosures.

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Item 3. Quantitative and Qualitative Disclosures about Market Risk

During the nine months ended September 30, 2016, there have been no material changes from the disclosures about market risk provided in our Annual Report on Form 10-K for the year ended December 31, 2015.

Item 4. Controls and Procedures

Disclosure Controls and Procedures

We maintain “disclosure controls and procedures,” as such term is defined in Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of 1934, as amended (“Exchange Act”), that are designed to ensure that information required to be disclosed by us in reports that we file or submit under the Exchange Act is recorded, processed, summarized, and reported within the time periods specified in Securities and Exchange Commission rules and forms, and that such information is accumulated and communicated to our management, including our Chief Executive Officer ("CEO") and Chief Financial Officer ("CFO"), as appropriate, to allow for timely decisions regarding required disclosure. In designing and evaluating our disclosure controls and procedures, management recognized that disclosure controls and procedures, no matter how well conceived and operated, can provide only reasonable, not absolute, assurance that the objectives of the disclosure controls and procedures are met. Additionally, in designing disclosure controls and procedures, our management necessarily was required to apply its judgment in evaluating the cost-benefit relationship of possible disclosure controls and procedures. The design of any disclosure controls and procedures also is based in part upon certain assumptions about the likelihood of future events, and there can be no assurance that any design will succeed in achieving its stated goals under all potential future conditions.

Subject to the limitations noted above, our management, with the participation of our CEO and CFO, has evaluated the effectiveness of the design and operation of our disclosure controls and procedures as of the period covered by this Quarterly Report on Form 10-Q. Based on that evaluation, the CEO and CFO have concluded that, as of such date, our disclosure controls and procedures were effective to meet the objective for which they were designed and operate at the reasonable assurance level.

Changes to Internal Control Over Financial Reporting

We identified no changes in internal control over financial reporting that occurred during our quarter ended September 30, 2016 that have materially affected, or that are reasonably likely to materially affect, our internal control over financial reporting.

PART II – OTHER INFORMATION

Item 1. Legal Proceedings

See Note 12, “Legal Proceedings” in the Notes to Condensed Consolidated Financial Statements of Part I, Item 1 of this Quarterly Report on Form 10-Q.

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Item 1A. Risk Factors

Our settlement with government agencies in connection with violations by us of the U.S. Foreign Corrupt Practices Act could have a material adverse effect on our business, results of operations and financial condition.

As previously disclosed, we entered into a non-prosecution agreement (NPA) with the U.S. Department of Justice (DOJ) and the Securities and Exchange Commission (SEC) and consented to the entry of an Order by the SEC (SEC Order), effective November 3, 2014, which actions resolved both the DOJ and the SEC investigations into our violations of the U.S. Foreign Corrupt Practices Act (FCPA). Under the terms of the NPA and the SEC Order, we agreed to pay a financial penalty and certain amounts in disgorgement and interest as well as to compliance, reporting and cooperation obligations to be performed for two years. On October 28, 2016, the DOJ and SEC informed Bio-Rad that they do not intend to extend the NPA after it expires November 2, 2016.

Whether by virtue of disclosure of the NPA and the SEC Order or otherwise, we may be subject to investigations by foreign governments or further claims by third parties arising from conduct subject to the investigation or our other international operations. For additional information regarding further claims by third parties, see Note 12, “Legal Proceedings” in the Notes to Condensed Consolidated Financial Statements of Part I, Item 1 of this Quarterly Report on Form 10-Q. Many of our customers in our significant international operations are government agencies or state-owned or state-controlled universities, hospitals and laboratories. The disclosure of the NPA and the SEC Order could harm our reputation with these customers, which could materially adversely affect our business, results of operations and financial condition.

Our international operations expose us to additional costs and legal and regulatory risks, which could have a material adverse effect on our business, results of operations and financial condition.

We have significant international operations. We have direct distribution channels in over 30 countries outside the United States, and during the first nine months of 2016 our foreign subsidiaries generated 61% of our net sales. Compliance with complex foreign and U.S. laws and regulations that apply to our international operations increases our cost of doing business. These numerous and sometimes conflicting laws and regulations include, among others, data privacy requirements (including with respect to the invalidation of the U.S.-European Union safe harbor by the European Court of Justice, compliance with the EU-U.S. Privacy Shield recently adopted by the European Commission, and the upcoming requirements for compliance with the EU General Data Protection Regulation), labor relations laws, tax laws, anti-competition regulations, import and trade restrictions, export requirements, U.S. laws such as the FCPA and other U.S. federal laws and regulations established by the office of Foreign Asset Control, local laws such as the UK Bribery Act 2010 or other local laws which prohibit corrupt payments to governmental officials or certain payments or remunerations to customers.

Given the high level of complexity of these laws, there is a risk that we may inadvertently breach some provisions, for example, through fraudulent or negligent behavior of individual employees, our failure to comply with certain formal documentation requirements, or otherwise. Our success depends, in part, on our ability to anticipate these risks and manage these challenges through policies, procedures and internal controls. However, we have a dispersed international sales organization, and we use distributors and agents in many of our international operations. This structure makes it more difficult for us to ensure that our international selling operations comply with our global policies and procedures.

Violations of these laws and regulations could result in fines, criminal sanctions against us, our officers or our employees, requirements to obtain export licenses, cessation of business activities in sanctioned countries, implementation of compliance programs, and prohibitions on the conduct of our business. Violations of laws and regulations also could result in prohibitions on our ability to offer our products in one or more countries and could materially damage our reputation, our brand, our international expansion efforts, our ability to attract and retain employees, or our business, results of operations and financial condition. See also our risk factor regarding government regulations below.

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The industries and market segments in which we operate are highly competitive, and we may not be able to compete effectively.

The life science and clinical diagnostics markets are each highly competitive. Some of our competitors have merged, and some of our competitors have greater financial resources than we do and are less leveraged than we are, making them better equipped to license technologies and intellectual property from third parties or to fund research and development, manufacturing and marketing efforts. Moreover, competitive and regulatory conditions in many markets in which we operate restrict our ability to fully recover, through price increases, higher costs of acquired goods and services resulting from inflation and other drivers of cost increases. Many public tenders have become more competitive due to governments lengthening the commitments of their public tenders to multiple years, which reduce the number of tenders in which we can participate annually. Because the value of these multiple-year tenders is so high, our competitors have been more aggressive with their pricing. Our failure to compete effectively and/or pricing pressures resulting from competition could adversely affect our business, results of operations and financial condition. 

We may not be able to grow our business because of our failure to develop new or improved products.

Our future growth depends in part on our ability to continue to improve our product offerings and develop and introduce new product lines and extensions that integrate technological advances. In particular, we may not be able to keep up with changes in the clinical diagnostics industry, such as the trend toward molecular diagnostics or point-of-care tests. If we are unable to integrate technological advances into our product offerings or to design, develop, manufacture and market new product lines and extensions successfully and in a timely manner, our business, results of operations and financial condition will be adversely affected. We have experienced product launch delays in the past, and may do so in the future. We cannot assure you that our product and process development efforts will be successful or that new products we introduce will achieve market acceptance. Failure to launch successful new products or improvements to existing products may cause our products to become obsolete, which could harm our business, results of operations and financial condition.

We are subject to foreign currency exchange fluctuations, which could have a material adverse effect on our results of operations and financial condition.

As stated above, a significant portion of our operations and sales are outside of the United States. When we make purchases and sales in currencies other than the U.S. dollars, we are exposed to fluctuations in foreign currencies relative to the U.S. dollar that may adversely affect our results of operations and financial condition. Our international sales are largely denominated in local currencies. As a result, the strengthening of the U.S. dollar negatively impacts our consolidated net sales expressed in U.S. dollars. Conversely, when the U.S. dollar weakens, our expenses at our international sites increase. In addition, the volatility of other currencies, such as the Swiss Franc, Brazilian Real and Russian Ruble, may negatively impact our operations outside of the United States and increase our costs to hedge against currency fluctuations. We cannot assure you that future shifts in currency exchange rates will not have a material adverse effect on our results of operations and financial condition.

We may experience difficulties implementing our new global enterprise resource planning system.

We are engaged in a multi-year implementation of a new global enterprise resource planning system (ERP). The ERP is designed to efficiently maintain our books and records and provide information important to the operation of our business to our management team. The ERP will continue to require significant investment of human and financial resources. In implementing the ERP, we may experience significant delays, increased costs and other difficulties. Any significant disruption or deficiency in the design and implementation of the ERP could adversely affect our ability to process orders, ship product, send invoices and track payments, fulfill contractual obligations or otherwise operate our business. For example, we experienced system implementation issues in our Clinical Diagnostics segment during our first deployment that impacted invoicing and caused an increase in accounts receivable. In our second deployment, which we launched in July 2015, we experienced delays in manufacturing

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and logistics, which adversely impacted our sales. We may experience similar and other issues with our upcoming third deployment. While we have invested significant resources in planning, project management and training, additional and significant implementation issues may arise. In addition, our efforts to centralize various business processes and functions within our organization in connection with our ERP implementation may disrupt our operations and negatively impact our business, results of operations and financial condition.

Recent and planned changes to our organizational structure and executive management team could negatively impact our business.

We made significant changes to our organizational structure in 2014 and 2015. We functionalized our manufacturing and selling organizations globally and separated them from our marketing and research and development organizations. Specifically, we combined our international selling organization with our North American selling divisions into one global selling group and consolidated our manufacturing, procurement and logistics operations into one global supply chain group. We also created new management positions to head each of these groups. In addition, we appointed new executives to head each of our Life Science and Clinical Diagnostics segments, and we appointed a Chief Operating Officer. We also restructured our Life Science segment based on functional groups rather than product line divisions. In addition, we are in the process of reorganizing the structure of our European organization. These changes may have unintended consequences, such as distraction of our management and employees, business disruption, attrition of our workforce, inability to attract or retain key employees, and reduced employee morale or productivity.

Our failure to establish and maintain effective internal control over financial reporting could result in material misstatements in our financial statements, our failure to meet our reporting obligations and cause investors to lose confidence in our reported financial information, which in turn could cause the trading price of our common stock to decline.

Maintaining effective internal control over financial reporting is necessary for us to produce reliable financial statements. As previously disclosed, in connection with our assessment of the effectiveness of internal control over financial reporting and the preparation of our financial statements for the year ended December 31, 2013, we identified a material weakness in the design of monitoring controls over operations at certain of our locations both within the United States and overseas, as well as a lack of documentation required to operate these controls appropriately. Although we remediated this material weakness as of December 31, 2014, we cannot assure you that additional material weaknesses in our internal control over financial reporting will not be identified in the future. For example, we previously identified different material weaknesses in internal controls at December 31, 2012 and December 31, 2010, both of which have been remediated.

Such material weaknesses have adversely affected us in the past and could affect us in the future, and the results of our periodic management evaluations and annual auditor attestation reports regarding the effectiveness of our internal control over financial reporting required by Section 404 of the Sarbanes-Oxley Act of 2002. Any failure to maintain new and more precise monitoring controls and improved detection and communication of financial misstatements across all levels of the organization could result in additional material weaknesses, result in material misstatements in our financial statements and cause us to fail to meet our reporting obligations. This could cause us to lose public confidence, and could cause the trading price of our common stock to decline. For further information regarding our controls and procedures, see Part I, Item 4 of this Quarterly Report on Form 10-Q.

Breaches of our information systems could have material adverse effect on our business and results of operations.

Through our sales and eCommerce channels, we collect and store confidential information that customers provide to, among other things, purchase products or services, enroll in promotional programs and register on our Web site. We also acquire and retain information about suppliers and employees in the normal course of business. We also create and maintain proprietary information that is critical to our business, such as our product designs and manufacturing processes. Despite recent initiatives to improve our technology systems, such as our enterprise

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resource planning implementation and the centralization of our global information technology organization, we could experience a significant data security breach. Computer hackers may attempt to penetrate our or our vendors’ information systems and, if successful, misappropriate confidential customer, supplier, employee or other business information, such as our intellectual property. Third parties could also gain control of our systems and use them for criminal purposes while appearing to be us. As a result, we could lose existing customers, have difficulty attracting new customers, be exposed to claims from customers, financial institutions, payment card associations, employees and other persons, have regulatory sanctions or penalties imposed, incur additional expenses or lose revenues as a result of a data privacy breach, or suffer other adverse consequences. Our operations and ability to process sales orders, particularly through our eCommerce channels, could also be disrupted. Any significant breakdown, intrusion, interruption, corruption, or destruction of our systems, as well as any data breaches, could have a material adverse effect on our business and results of operations. See also our risk factors regarding our ERP implementation above and our information technology systems below.

Risks relating to intellectual property rights may negatively impact our business.

We rely on a combination of copyright, trade secret, patent and trademark laws and third-party nondisclosure agreements to protect our intellectual property rights and products.  However, we cannot assure you that our intellectual property rights will not be challenged, invalidated, circumvented or rendered unenforceable, or that meaningful protection or adequate remedies will be available to us.  For instance, unauthorized third parties have attempted to copy our intellectual property, reverse engineer or obtain and use information that we regard as proprietary, or have developed equivalent technologies independently, and may do so in the future.  Additionally, third parties have asserted patent, copyright and other intellectual property rights to technologies that are important to us, and may do so in the future. If we are unable to license or otherwise access protected technology used in our products, or if we lose our rights under any existing licenses, we could be prohibited from manufacturing and marketing such products. From time to time, we also must enforce our patents or other intellectual property rights or defend ourselves against claimed infringement of the rights of others through litigation. As a result, we could incur substantial costs, be forced to redesign our products, or be required to pay damages to an infringed party.  Any of the foregoing matters could adversely impact our business, results of operations and financial condition.

Global economic conditions could continue to adversely affect our operations.

In recent years, we have been faced with very challenging global economic conditions. Further deterioration in the global economic environment may result in decreased demand for our products, increased competition, downward pressure on the prices for our products and longer sales cycles. A weakening of macroeconomic conditions may also adversely affect our suppliers, which could result in interruptions in supply in the future. We have also experienced delays in collecting receivables in certain countries in Western Europe, and we may experience similar delays in these and other countries or regions experiencing liquidity problems. As of September 30, 2016, we had accounts receivable, net of allowance for doubtful accounts, in Spain, Italy, Greece and Portugal of $38.1 million. In addition, a slowing of growth in the Chinese economy and in emerging markets, especially those oil-producing countries that have been affected by the recent decline in oil prices, could adversely affect our business, results of operations or financial condition. We also are monitoring developments following the recent referendum in the United Kingdom to leave the European Union to determine if there will be any potential impact on our business.

Reductions in government funding and the capital spending programs of our customers could have a material adverse effect on our business, results of operations or financial condition.

Our customers include universities, clinical diagnostics laboratories, government agencies, hospitals and pharmaceutical, biotechnology and chemical companies.  The capital spending programs of these institutions and companies have a significant effect on the demand for our products.  Such programs are based on a wide variety of factors, including the resources available to make such purchases, the availability of funding from grants by governments or government agencies, the spending priorities for various types of equipment and the policies regarding capital expenditures during industry downturns or recessionary periods.  If government funding to our

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customers were to decrease, or if our customers were to decrease or reallocate their budgets in a manner adverse to us, our business, results of operations or financial condition could be materially and adversely affected.

Changes in the healthcare industry could have an adverse effect on our business, results of operations and financial condition.

There have been, and will continue to be, significant changes in the healthcare industry in an effort to reduce costs. These changes include:

• The trend towards managed care, together with healthcare reform of the delivery system in the United States and efforts to reform in Europe, has resulted in increased pressure on healthcare providers and other participants in the healthcare industry to reduce selling prices.  Consolidation among healthcare providers has resulted in fewer, more powerful groups, whose purchasing power gives them cost containment leverage.  In particular, there has been a consolidation of blood transfusion centers, as well as an industry decline in the number of blood transfusions. These industry trends and competitive forces place constraints on the levels of overall pricing, and thus could have a material adverse effect on our gross margins for products we sell in clinical diagnostic markets.

• Third party payors, such as Medicare and Medicaid in the United States, have reduced their reimbursements for certain medical products and services. Our Clinical Diagnostics business is impacted by the level of reimbursement available for clinical tests from third party payors. In the United States payment for many diagnostic tests furnished to Medicare fee-for-service beneficiaries is made based on the Medicare Clinical Laboratory Fee Schedule (CLFS), a fee schedule established and adjusted from time to time by the Centers for Medicare and Medicaid Services (CMS). Some commercial payors are guided by the CLFS in establishing their reimbursement rates. Clinicians may decide not to order clinical diagnostic tests if third party payments are inadequate, and we cannot predict whether third party payors will offer adequate reimbursement for tests utilizing our products to make them commercially attractive. Legislation, such as the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act (PPACA) and the Middle Class Tax Relief and Job Creation Act of 2012, has reduced the payments for clinical laboratory services paid under the CLFS. In addition, the Protecting Access to Medicare Act of 2014 will make significant changes to the way Medicare will pay for clinical laboratory services, which will further reduce reimbursement rates.

• The PPACA has also imposed a 2.3% excise tax on the sales of certain medical devices in the U.S., which we are required to pay on most of our United States Clinical Diagnostic sales. However, the Consolidated Appropriations Act, 2016 (Pub. L. 114-113), signed into law on December 18, 2015, includes a two year moratorium on the medical device excise tax during the period beginning on January 1, 2016, and ending on December 31, 2017.

To the extent that the healthcare industry seeks to address the need to contain costs stemming from reform measures such as those contained in the PPACA and the Protecting Access to Medicare Act of 2014, or in future legislation, by limiting the number of clinical tests being performed or the amount of reimbursement available for such tests, our business, results of operations and financial condition could be adversely affected.  If these changes in the healthcare markets in the United States and Europe continue, we could be forced to alter our approach in selling, marketing, distributing and servicing our products.

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We are subject to substantial government regulation, and any changes in regulation or violations of regulations by us could adversely affect our business, prospects, results of operations or financial condition.

Some of our products (primarily our Clinical Diagnostic products), production processes and marketing are subject to U.S. federal, state and local, and foreign regulation, including by the FDA in the United States and its foreign counterparts.  The FDA regulates our Clinical Diagnostic products as medical devices, and we are subject to significant regulatory clearances or approvals to market our Clinical Diagnostic products and other requirements including, for example, recordkeeping and reporting requirements, such as the FDA’s medical device reporting regulations and reporting of corrections and removals. The FDA has broad regulatory and enforcement powers. If the FDA determines that we have failed to comply with applicable regulatory requirements, it can impose a variety of enforcement actions ranging from public warning letters, fines, injunctions, consent decrees and civil penalties to suspension or delayed issuance of approvals, seizure or recall of our products, total or partial shutdown of production, withdrawal of approvals or clearances already granted, and criminal prosecution.

The FDA can also require us to repair, replace or refund the cost of devices that we manufactured or distributed.

In addition, the FDA may change its clearance and approval policies, adopt additional regulations or revise existing regulations, or take other actions, which may prevent or delay approval or clearance of our products or impact our ability to modify our currently approved or cleared products on a timely basis. Changes in the FDA’s review of certain clinical diagnostic products referred to as laboratory developed tests, which are tests developed by a single laboratory for use only in that laboratory, could affect some of our customers who use our Life Science instruments for laboratory developed tests. In the past, the FDA has chosen to not enforce applicable regulations and has not reviewed such tests for approval. However, the FDA has recently issued guidance that it will begin enforcing its medical device requirements, including premarket submission requirements, to such tests. Any delay in, or failure to receive or maintain, clearance or approval for our products could prevent us from generating revenue from these products and adversely affect our business operations and financial results. Additionally, the FDA and other regulatory authorities have broad enforcement powers. Regulatory enforcement or inquiries, or other increased scrutiny on us, could affect the perceived safety and efficacy of our products and dissuade our customers from using our products.

Many foreign governments have similar rules and regulations regarding the importation, registration, labeling, sale and use of our products. Such agencies may also impose new requirements that may require us to modify or re-register products already on the market or otherwise impact our ability to market our products in those countries. For example, Europe published draft regulations in June 2016 that include broad changes to its regulations regarding in vitro diagnostic devices and medical devices, including stricter product labeling requirements, Russia has recently enacted more stringent medical product registration and labeling regulations, China has enacted stricter labeling requirements, and we expect other countries, such as Brazil and India, to impose more regulations that impact our product registrations. Due to these evolving and diverse requirements, we face uncertain product approval timelines, additional time and effort to comply, reduced sales and potential fines for noncompliance. Increasing protectionism in such countries also impedes our ability to compete with local companies. For example, we may not be able to participate in certain public tenders in Russia because of increasing measures to restrict access to such tenders for companies without local manufacturing capabilities. Specifically, a resolution passed by Russia in February 2015 prohibits the procurement of certain types of medical devices by Russian state entities from foreign companies provided there are a sufficient number of Russian manufacturers submitting tenders. Such regulations could adversely affect our business, results of operations and financial condition.

We are also subject to government regulation of the use and handling of a number of materials and controlled substances.  The U.S. Drug Enforcement Administration establishes registration, security, recordkeeping, reporting, storage, distribution and other requirements for controlled substances pursuant to the Controlled Substances Act of 1970. Failure to comply with present or future laws and regulations could result in substantial liability to us, suspension or cessation of our operations, restrictions on our ability to expand at our present locations or require us to make significant capital expenditures or incur other significant expenses.

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We cannot assure you that we will be able to integrate acquired companies, products or technologies into our company successfully, or we may not be able to realize the anticipated benefits from the acquisitions.

As part of our overall business strategy, we pursue acquisitions of and investments in complementary companies, products and technologies. In order to be successful in these activities, we must, among other things:

• assimilate the operations and personnel of acquired companies;

• retain acquired business customers;

• minimize potential disruption to our ongoing business;

• retain key technical and management personnel;

• integrate acquired companies into our strategic and financial plans;

• accurately assess the value of target companies, products and technologies;

• comply with new regulatory requirements;

• harmonize standards, controls, procedures and policies;

• minimize the impact to our relationships with our employees and customers; and

• assess, document and remediate any deficiencies in disclosure controls and procedures and internal control over financial reporting.

The benefits of any acquisition may prove to be less than anticipated and may not outweigh the costs reported in our financial statements.  Completing any potential future acquisitions could cause significant diversion of our management’s time and resources.  If we acquire new companies, products or technologies, we may be required to assume contingent liabilities or record impairment charges for goodwill and other intangible assets over time. We cannot assure you that we will successfully overcome these risks or any other problems we encounter in connection with any acquisitions, and any such acquisitions could adversely affect our business, results of operations and financial condition.

Product quality and liability issues could harm our reputation and negatively impact our business, results of operations and financial condition.

We must adequately address quality issues associated with our products, including defects in our engineering, design and manufacturing processes, as well as defects in third-party components included in our products. Our instruments, reagents and consumables are complex, and identifying the root cause of quality issues, especially those affecting reagents or third-party components, is difficult. We may incur significant costs and expend substantial time in researching and remediating such issues. Quality issues could also delay our launching or manufacturing of new products. In addition, quality issues, unapproved uses of our products, or inadequate disclosure of risks related to our products, could result in product recalls or product liability or other claims being brought against us. These issues could harm our reputation, impair our relationship with existing customers and harm our ability to attract new customers, which could negatively impact our business, results of operations and financial condition.

Lack of key personnel could hurt our business.

Our products are very technical in nature. In general, only highly qualified and well-trained scientists have the necessary skills to develop, market and sell our products, and many of our manufacturing positions require very specialized knowledge and skills.  In addition, the global nature of our business also requires that we have sophisticated and experienced staff to comply with increasingly complex international laws and regulations. We face intense competition for these professionals from our competitors, customers, marketing partners and other companies throughout our industry. In particular, the job market in Northern California, where many of our employees are located, is very competitive. If we do not offer competitive compensation and benefits, we may fail to retain or attract a sufficient number of qualified personnel, which could impair our ability to properly run our business.

In some cases we rely on temporary personnel or consultants, and we may do so in the future. Such temporary personnel or consultants may lack the knowledge and/or specific skills necessary for our business, require time to

44

train without benefiting us through extended employment and increase our costs. In addition, as noted above, our strategic initiatives, such as our internal restructuring and ERP implementation, may be burdensome and disruptive and lead to employee dissatisfaction and attrition.

A reduction or interruption in the supply of components and raw materials could adversely affect our manufacturing operations and related product sales.

The manufacture of many of our products requires the timely delivery of sufficient amounts of quality components and materials. We manufacture our products in numerous manufacturing facilities around the world. We acquire our components and materials from many suppliers in various countries. We work closely with our suppliers to ensure the continuity of supply but we cannot guarantee these efforts will always be successful. Further, while we seek to diversify our sources of components and materials, in certain instances we acquire components and materials from a sole supplier. In addition, due to the regulatory environment in which we operate, we may be unable to quickly establish additional or replacement sources for some components or materials. If our supply is reduced or interrupted or of poor quality, and we are unable to develop alternative sources for such supply, our ability to manufacture our products in a timely or cost-effective manner could be adversely affected, which would adversely affect our ability to sell our products.

If our information technology systems are disrupted, or if we fail to successfully implement, manage and integrate our information technology and reporting systems, our business, results of operations and financial condition could be harmed.

Our information technology (IT) systems are an integral part of our business, and a serious disruption of our IT systems could have a material adverse effect on our business, results of operations and financial condition. We depend on our IT systems to process orders, manage inventory and collect accounts receivable.  Our IT systems also allow us to efficiently purchase products from our suppliers and ship products to our customers on a timely basis, maintain cost-effective operations and provide customer service.  We may experience disruption of our IT systems due to redundancy issues with our network servers. We cannot assure you that our contingency plans will allow us to operate at our current level of efficiency.

Our ability to implement our business plan in a rapidly evolving market requires effective planning, reporting and analytical processes.  We expect that we will need to continue to improve and further integrate our IT systems, reporting systems and operating procedures by training and educating our employees with respect to these improvements and integrations on an ongoing basis in order to effectively run our business.  We may suffer interruptions in service, loss of data or reduced functionality when we upgrade or change systems. If we fail to successfully manage and integrate our IT systems, reporting systems and operating procedures, it could adversely affect our business, results of operations and financial condition. See also our risk factors regarding our ERP implementation and data security above and events beyond our control below.

Natural disasters, terrorist attacks, acts of war or other events beyond our control may cause damage or disruption to us and our employees, facilities, information systems, security systems, vendors and customers, which could significantly impact our business, results of operations and financial condition.

We have significant manufacturing and distribution facilities, including in the western United States, France, Switzerland, Germany and Singapore.  In particular, the western United States has experienced a number of earthquakes, wildfires, floods, landslides and other natural disasters in recent years.  These occurrences could damage or destroy our facilities which may result in interruptions to our business and losses that exceed our insurance coverage. In addition, strikes or other labor unrest at any of our sites or surrounding areas could cause disruption to our business.

Acts of terrorism, bioterrorism, violence or war could also affect the markets in which we operate, our business operations and strategic plans. Political unrest may affect our sales in certain regions, such as in Southeast Asia, the Middle East and Eastern Europe. In particular, the political turmoil in Ukraine, along with the response of the

45

Russian and U.S. governments to this situation, has the potential to impact our operations in Russia. Any of these events could adversely affect our business, results of operations and financial condition.

Environmental, health and safety regulations and enforcement proceedings may negatively impact our business, results of operations and financial condition.

Our operations are subject to federal, state, local and foreign environmental laws and regulations that govern such activities as transportation of goods, emissions to air and discharges to water, as well as handling and disposal practices for solid, hazardous and medical wastes.  In addition to environmental laws that regulate our operations, we are also subject to environmental laws and regulations that create liability and clean-up responsibility for spills, disposals or other releases of hazardous substances into the environment as a result of our operations or otherwise impacting real property that we own or operate.  The environmental laws and regulations also subject us to claims by third parties for damages resulting from any spills, disposals or releases resulting from our operations or at any of our properties. We must also comply with various health and safety regulations in the United States and abroad in connection with our operations.

We may in the future incur capital and operating costs to comply with currently existing laws and regulations, and possible new statutory enactments, and these expenditures may be significant.  We have incurred, and may in the future incur, fines related to environmental matters and/or liability for costs or damages related to spills or other releases of hazardous substances into the environment at sites where we have operated, or at off-site locations where we have sent hazardous substances for disposal.  We cannot assure you, however, that such matters or any future obligations to comply with environmental or health and safety laws and regulations will not adversely affect our business, results of operations or financial condition.

We may be subject to additional tax liabilities.

We are subject to income taxes in the United States and many foreign jurisdictions. We calculate our provision for income taxes in each jurisdiction in which we operate. Significant judgment is required in determining our worldwide provision for income taxes and in the ordinary course of business, there are many tax positions taken where the ultimate resolution is uncertain. We are subject to the examination of our tax positions in the United States and foreign jurisdictions. Taxing authorities have disagreed with our judgment in the past and may disagree with positions we take in the future resulting in assessments of additional taxes. Economic and political pressures to increase tax revenues in various jurisdictions may make resolving tax disputes more difficult. For example, in recent years, the tax authorities in Europe have disagreed with our tax positions related to hybrid debt, research and development credits, transfer pricing and indirect taxes, among others. We regularly assess the likelihood of the outcome resulting from these examinations to determine the adequacy of our provision for income taxes. Although we believe our tax estimates are reasonable, the final determination of tax audits and any related litigation could be materially different from our historical income tax provisions and accruals. The results of an audit or litigation could have a material effect on our consolidated financial statements in the period or periods for which that determination is made. Changes in factors outside of our control, such as changes in tax laws or rates, changes in the interpretation of tax laws or changes in the jurisdictional mix of our earnings could adversely affect our financial position and results of operations.

Our debt may restrict our future operations.

We have substantial debt and have the ability to incur additional debt. As of September 30, 2016, we had approximately $434.4 million of outstanding indebtedness. In addition, we have a revolving credit facility that provides for up to $200.0 million, $0.8 million of which has been utilized for domestic standby letters of credit. Our incurrence of substantial amounts of debt may have important consequences.  For instance, it could:

• make it more difficult for us to satisfy our financial obligations, including those relating to our outstanding debt;

46

• require us to dedicate a substantial portion of our cash flow from operations to the payment of interest and principal due under our debt, which will reduce funds available for other business purposes;

• increase our vulnerability to general adverse economic and industry conditions;

• limit our flexibility in planning for, or reacting to, changes in our business and the industries in which we operate;

• place us at a competitive disadvantage compared with some of our competitors that have less debt; and

• limit our ability to obtain additional financing required to fund working capital and capital expenditures and for other general corporate purposes.

Our existing credit facility and the terms of our other debt instruments, including agreements we may enter in the future, contain or will contain covenants imposing significant restrictions on our business.  These restrictions may affect our ability to operate our business and may limit our ability to take advantage of potential business opportunities as they arise.  These covenants place restrictions on our ability to, among other things: incur additional debt; acquire other businesses or assets through merger or purchase; create liens; make investments; enter into transactions with affiliates; sell assets; in the case of some of our subsidiaries, guarantee debt; and declare or pay dividends, redeem stock or make other distributions to stockholders. Our existing credit facility also requires that we comply with certain financial ratios, including a maximum consolidated leverage ratio test and a minimum consolidated interest coverage ratio test.

Our ability to comply with these covenants may be affected by events beyond our control, including prevailing economic, financial and industry conditions.  The breach of any of these restrictions could result in a default.  An event of default under our debt agreements would permit some of our lenders to declare all amounts borrowed from them to be due and payable, together with accrued and unpaid interest. In addition, acceleration of our other indebtedness may cause us to be unable to make interest payments on our outstanding notes and repay the principal amount of our outstanding notes or may cause the future subsidiary guarantors, if any, to be unable to make payments under the guarantees.

We are subject to healthcare fraud and abuse laws and regulations and could face substantial penalties if we are unable to fully comply with such laws.

We are subject to healthcare fraud and abuse regulation and enforcement by both the U.S. federal government and the U.S. states and foreign governments in which we conduct our business. These healthcare laws and regulations include, for example:

• the U.S. federal Anti-Kickback Statute, which prohibits, among other things, persons or entities from soliciting, receiving, offering or providing remuneration, directly or indirectly, in return for or to induce either the referral of an individual for, or the purchase order or recommendation of, any item or services for which payment may be made under a federal healthcare program such as the Medicare and Medicaid programs;

• U.S. federal false claims laws, which prohibit, among other things, individuals or entities from knowingly presenting, or causing to be presented, claims for payment from Medicare, Medicaid, or other third-party payors that are false or fraudulent. In addition, the U.S. federal government may assert that a claim including items or services resulting from a violation of the federal Anti-Kickback Statute constitutes a false or fraudulent claim for purposes of the false claims statutes;

• the U.S. Physician Payment Sunshine Act, which requires certain manufacturers of drugs, biologics, devices and medical supplies to record any transfers of value to U.S. physicians and U.S. teaching hospitals;

• the Health Insurance Portability and Accountability Act ("HIPAA"), as amended by the Health Information Technology for Economic and Clinical Health Act, which governs the conduct of certain electronic healthcare transactions and protects the security and privacy of protected health information; and

47

• state or foreign law equivalents of each of the U.S. federal laws above, such as anti-kickback and false claims laws, which may apply to items or services reimbursed by any third-party payor, including commercial insurers.

These laws will continue to impose administrative, cost and compliance burdens on us. The shifting compliance environment and the need to build and maintain robust systems to comply with multiple jurisdictions with different compliance and/or reporting requirements increases the possibility that a healthcare company may violate one or more of these requirements. In addition, any action against us for violation of these laws, even if we successfully defend against it, could cause us to incur significant legal expenses and divert our management’s attention from the operation of our business. If our operations are found to be in violation of any of the laws described above or any other governmental regulations that apply to us, we may be subject to penalties, including civil and criminal penalties, damages, fines, exclusion from the Medicare and Medicaid programs, and the curtailment or restructuring of our operations, any of which could adversely affect our ability to operate our business, results of operations and financial condition.

We may incur losses in future periods due to write-downs in the value of financial instruments.

We have positions in a variety of financial instruments including asset backed securities and other similar instruments. Financial markets are quite volatile and the markets for these securities can be illiquid.  The value of these securities will continue to be impacted by external market factors including default rates, changes in the value of the underlying property, such as residential or commercial real estate, rating agency actions, the prices at which observable market transactions occur and the financial strength of various entities, such as financial guarantors who provide insurance for the securities. Should we need to convert these positions to cash, we may not be able to sell these instruments without significant losses due to current debtor financial conditions or other market considerations.

Regulations related to “conflict minerals” could adversely impact our business.

As part of the Dodd-Frank Wall Street Reform and Consumer Protection Act, the SEC adopted disclosure requirements regarding the use of certain minerals, known as conflict minerals, which are mined from the Democratic Republic of Congo (DRC) and adjoining countries, as well as procedures regarding a manufacturer's efforts to identify the sourcing of such minerals and metals produced from those minerals. In June 2016, the European Union announced an agreement in principle for a European Union regime on conflict minerals, with the technical details and the text of regulations to come in the future. We have incurred, and will continue to incur, additional costs in order to comply with the SEC’s disclosure requirements. In addition, we might incur further costs due to possible changes to our products, processes, or sources of supply as a consequence of our due diligence activities. As our supply chain is complex, we may not be able to sufficiently verify the origins of the specified minerals used in our products through our due diligence procedures, which may harm our reputation. In addition, we may encounter challenges to satisfy those customers who require that all of the components of our products be certified as “DRC conflict free”, which could place us at a competitive disadvantage if we do not do so. We filed our report for the calendar year 2015 with the SEC on May 27, 2016.

Risks related to our common stock

A significant majority of our voting stock is held by the Schwartz family, which could lead to conflicts of interest.

We have two classes of voting stock: Class A Common Stock and Class B Common Stock. With a few exceptions, holders of Class A and Class B Common Stock vote as a single class.  When voting as a single class, each share of Class A Common Stock is entitled to one-tenth of a vote, while each share of Class B Common Stock has one vote. In the election or removal of directors, the classes vote separately and the holders of Class A Common Stock are entitled to elect 25% of the Board of Directors, with holders of Class B Common Stock electing the remaining directors.

48

As a result of the Schwartz family's ownership of our Class A and Class B Common Stock, they are able to elect a majority of our directors, effect fundamental changes in our direction and control matters affecting us, including the determination of business opportunities that may be suitable for our company.  The Schwartz family may exercise its control over us according to interests that are different from other investors’ or debtors’ interests. In particular, this concentration of ownership and voting power may have the effect of delaying or preventing a change in control of our company.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

None.

Item 3. Defaults Upon Senior Securities

None.

Item 4. Mine Safety Disclosures

Not applicable.

Item 5. Other Information

None.

49

Item 6. Exhibits

(a)  Exhibits

The following documents are filed as part of this report:

Exhibit No.
31.1	Chief Executive Officer Section 302 Certification
31.2	Chief Financial Officer Section 302 Certification
32.1	Chief Executive Officer Certification pursuant to 18 U.S.C Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
32.2	Chief Financial Officer Certification pursuant to 18 U.S.C Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
101.INS	The instance document does not appear in the interactive data file because its XBRL tags are embedded within the inline XBRL document.
101.SCH	XBRL Taxonomy Extension Schema Document
101.CAL	XBRL Taxonomy Extension Calculation Linkbase Document
101.DEF	XBRL Taxonomy Extension Definition Linkbase Document
101.LAB	XBRL Taxonomy Extension Labels Linkbase Document
101.PRE	XBRL Taxonomy Extension Presentation Linkbase Document

50

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereto duly authorized.

BIO-RAD LABORATORIES, INC.
(Registrant)
Date:	November 2, 2016	/s/ Norman Schwartz
		Norman Schwartz, Chairman of the Board,
		President and Chief Executive Officer
Date:	November 2, 2016	/s/ Christine A. Tsingos
		Christine A. Tsingos, Executive Vice President,
		Chief Financial Officer

51

EX-31.1

Exhibit 31.1

Certification of Chief Executive Officer Required By

Exchange Act Rules 13a-14(a) and 15d-14(a)

I, Norman Schwartz, certify that:

1. I have reviewed this quarterly report on Form 10-Q of Bio-Rad Laboratories, Inc.

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report fairly present, in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13-a-15(f) and 15d-15(f)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5. The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date:	November 2, 2016	/s/ Norman Schwartz
		Norman Schwartz, Chairman of the Board,
		President and Chief Executive Officer

EX-31.2

Exhibit 31.2

Certification of Chief Financial Officer Required By

Exchange Act Rules 13a-14(a) and 15d-14(a)

I, Christine A. Tsingos, certify that:

1. I have reviewed this quarterly report on Form 10-Q of Bio-Rad Laboratories, Inc.

2. Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

3. Based on my knowledge, the financial statements, and other financial information included in this report fairly present, in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

4. The registrant's other certifying officer and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13-a-15(f) and 15d-15(f)) for the registrant and have:

(a) Designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

(b) Designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles;

(c) Evaluated the effectiveness of the registrant's disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

(d) Disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

5. The registrant's other certifying officer and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant's auditors and the audit committee of the registrant's board of directors (or persons performing the equivalent functions):

(a) All significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

(b) Any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant's internal control over financial reporting.

Date:	November 2, 2016	/s/ Christine A.Tsingos
		Christine A. Tsingos
		Executive Vice President,
		Chief Financial Officer

EX-32.1

Exhibit 32.1

Certification of Periodic Report

I, Norman Schwartz, Chief Executive Officer of Bio-Rad Laboratories, Inc. (the “Company”), certify, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, 18 U.S.C. Section 1350, that:

(1) the Quarterly Report on Form 10-Q of the Company for the quarter ended September 30, 2016 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (15 U.S.C. 78m); and

(2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date:	November 2, 2016	/s/ Norman Schwartz
		Norman Schwartz, Chairman of the Board,
		President and Chief Executive Officer

The foregoing certification is being furnished solely pursuant to 18 U.S.C. Section 1350 and is not being filed as part of the Report or as a separate disclosure document.

EX-32.2

Exhibit 32.2

Certification of Periodic Report

I, Christine A. Tsingos, Chief Financial Officer of Bio-Rad Laboratories, Inc. (the “Company”), certify, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, 18 U.S.C. Section 1350, that:

(1) the Quarterly Report on Form 10-Q of the Company for the quarter ended September 30, 2016 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 (15 U.S.C. 78m); and

(2) the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date:	November 2, 2016	/s/ Christine A. Tsingos
		Christine A. Tsingos
		Executive Vice President,
		Chief Financial Officer

The foregoing certification is being furnished solely pursuant to 18 U.S.C. Section 1350 and is not being filed as part of the Report or as a separate disclosure document.

XML

Document and Entity Information - shares	9 Months Ended
	Sep. 30, 2016	Oct. 27, 2016
Entity Registrant Name	BIO RAD LABORATORIES INC
Entity Central Index Key	0000012208
Current Fiscal Year End Date	--12-31
Entity Filer Category	Large Accelerated Filer
Document Type	10-Q
Document Period End Date	Sep. 30, 2016
Document Fiscal Year Focus	2016
Document Fiscal Period Focus	Q3
Amendment Flag	false
Entity Well-known Seasoned Issuer	Yes
Entity Voluntary Filers	No
Entity Current Reporting Status	Yes
Common Class A [Member]
Entity Common Stock, Shares Outstanding		24,417,421
Common Class B [Member]
Entity Common Stock, Shares Outstanding		5,123,819

XML

Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2016	Dec. 31, 2015
ASSETS:
Cash and cash equivalents	$ 417,939	$ 457,549
Short-term investments	388,177	328,718
Restricted investments	4,210	4,210
Accounts receivable, net	367,662	391,485
Inventories:
Raw materials	117,562	109,928
Work in process	130,964	114,438
Finished goods	307,832	265,858
Total inventories	556,358	490,224
Other current assets	115,757	105,410
Total current assets	1,850,103	1,777,596
Property, plant and equipment, at cost	1,217,176	1,117,086
Less: accumulated depreciation and amortization	(742,509)	(679,396)
Property, plant and equipment, net	474,667	437,690
Goodwill, net	506,573	495,948
Purchased intangibles, net	220,904	214,026
Other investments	903,658	719,840
Other assets	63,821	64,618
Total assets	4,019,726	3,709,718
LIABILITIES AND STOCKHOLDERS' EQUITY:
Accounts payable, accrued payroll and employee benefits	280,453	280,248
Current maturities of long-term debt and notes payable	297	298
Income and other taxes payable	22,274	29,339
Other current liabilities	139,694	131,466
Total current liabilities	442,718	441,351
Long-term debt, net of current maturities	434,137	433,883
Deferred income taxes	295,245	233,475
Deferred revenue	4,400	3,743
Other long-term liabilities	140,535	106,763
Total liabilities	1,317,035	1,219,215
Stockholders' equity:
Additional paid-in capital	324,636	300,408
Retained earnings	1,856,750	1,808,055
Accumulated other comprehensive income	521,403	382,138
Total stockholders' equity	2,702,691	2,490,503
Total liabilities and stockholders' equity	4,019,726	3,709,718
Common Class A [Member]
Stockholders' equity:
Common stock	2	2
Common Class B [Member]
Stockholders' equity:
Common stock	1	1
Treasury Class A [Member]
Stockholders' equity:
Treasury Stock, Value	(12)	(12)
Treasury Class B [Member]
Stockholders' equity:
Treasury Stock, Value	$ (89)	$ (89)

XML

Condensed Consolidated Balance Sheets Parenthetical - shares	Sep. 30, 2016	Dec. 31, 2015
Common Class A [Member]
Common Stock, Shares, Issued	24,417,541	24,230,448
Common Stock, Shares, Outstanding	24,417,419	24,230,326
Common Class B [Member]
Common Stock, Shares, Issued	5,124,738	5,130,558
Common Stock, Shares, Outstanding	5,123,821	5,129,641
Treasury Class A [Member]
Treasury Stock, Shares	122	122
Treasury Class B [Member]
Treasury Stock, Shares	917	917

XML

Condensed Consolidated Statements of Income (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Net sales	$ 508,745	$ 469,961	$ 1,496,719	$ 1,448,884
Cost of goods sold	229,276	206,509	672,989	635,729
Gross profit	279,469	263,452	823,730	813,155
Selling, general and administrative expense	201,452	187,445	596,704	568,845
Research and Development Expense	49,924	43,336	150,681	137,085
Segment profit (loss)	28,093	32,671	76,345	107,225
Interest expense	5,634	5,822	16,846	15,658
Foreign exchange losses, net	1,210	2,166	3,576	8,910
Other (income) expense, net	(1,439)	(732)	(13,824)	(8,992)
Income before income taxes	22,688	25,415	69,747	91,649
Provision for income taxes	(4,283)	(8,045)	(21,052)	(28,038)
Net income including noncontrolling interests			48,695	63,611
Net income attributable to Bio-Rad	$ 18,405	$ 17,370	$ 48,695	$ 63,611
Basic earnings per share:
Net income per share basic attributable to Bio-Rad	$ 0.63	$ 0.59	$ 1.66	$ 2.18
Weighted average common shares - basic	29,444	29,195	29,402	29,141
Diluted earnings per share:
Net income per share diluted attributable to Bio-Rad	$ 0.62	$ 0.59	$ 1.65	$ 2.17
Weighted average common shares - diluted	29,671	29,439	29,592	29,372

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Condensed Consolidated Statements of Comprehensive Income (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Net Income (Loss) Attributable to Parent	$ 18,405	$ 17,370	$ 48,695	$ 63,611
Foreign currency translation adjustments	3,423	(27,743)	22,936	(10,147)
Other Comprehensive Income (Loss), Pension and Other Postretirement Benefit Plans, Adjustment, Net of Tax, Portion Attributable to Parent	32	89	(73)	513
Net unrealized holding gains (losses) on available-for-sale investments net of tax expense	58,387	74,987	116,402	170,069
Total other comprehensive income (loss) net of tax	61,842	47,333	139,265	160,435
Comprehensive Income (Loss), Net of Tax, Including Portion Attributable to Noncontrolling Interest	$ 80,247	$ 64,703	$ 187,960	$ 224,046

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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015
Cash flows from operating activities:
Cash received from customers	$ 1,530,605	$ 1,443,672
Cash paid to suppliers and employees	(1,365,548)	(1,278,255)
Interest paid, net	(11,195)	(9,620)
Income tax payments, net	(37,373)	(15,646)
Investment proceeds and miscellaneous receipts, net	14,360	9,695
Excess tax benefits from share-based compensation	(1,094)	(3,242)
(Payments for) proceeds from forward foreign exchange contracts, net	(8,441)	(3,654)
Net cash provided by operating activities	121,314	150,258
Cash flows from investing activities:
Capital expenditures	(96,323)	(84,013)
Proceeds from dispositions of property, plant and equipment	378	41
Payments for acquisition and long-term investment	(11,785)	(3,490)
Payments for purchases of intangible assets	(6)	(1,375)
Payments for purchases of marketable securities and investments	(217,820)	(172,440)
Proceeds from sales of marketable securities and investments	59,687	56,630
Proceeds from maturities of marketable securities and investments	102,112	121,556
Net cash used in investing activities	(163,757)	(83,091)
Cash flows from financing activities:
Net borrowings from (payments for) line-of-credit arrangements and notes payable	0	74
Payments on long-term borrowings	(231)	(206)
Payments of contingent consideration	(3,500)	(2,983)
Proceeds from issuance of common stock for shared-based compensation	8,828	4,726
Excess tax benefits from share-based compensation	1,094	3,242
Net cash provided by financing activities	6,191	4,853
Effect of foreign exchange rate changes on cash	(3,358)	22,058
Net (decrease) increase in cash and cash equivalents	(39,610)	94,078
Cash and cash equivalents at beginning of period	457,549	413,251
Cash and cash equivalents at end of period	417,939	507,329
Adjustments to Reconcile Net Income to Cash Provided by Operating Activities [Abstract]
Net income	48,695	63,611
Adjustments, Noncash Items, to Reconcile Net Income to Cash Provided by Operating Activities [Abstract]
Depreciation and amortization	110,156	97,970
Share-based compensation	14,318	12,309
Gains on dispositions of securities	(93)	(19)
Excess tax benefits from share-based compensation	(1,094)	(3,242)
Changes in fair value of contingent consideration	(2,164)	(730)
Decrease in accounts receivable	32,650	16,996
Increase in inventories	(67,938)	(67,609)
(Increase) decrease in other current assets	(2,018)	2,620
(Decrease) increase in accounts payable and other current liabilities	(4,645)	17,869
(Decrease) increase in income taxes payable	(8,423)	14,760
(Decrease) increase in Deferred Income Taxes	(8,480)	2,350
Net decrease/increase in other long-term assets/liabilities	10,350	(6,627)
Net cash provided by operating activities	$ 121,314	$ 150,258

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1. Organization, Consolidation and Presentation of Financial Statements

9 Months Ended

Sep. 30, 2016

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Organization, Consolidation and Presentation of Financial Statements Disclosure

1.BASIS OF PRESENTATION AND USE OF ESTIMATES

Basis of Presentation

In this report, “Bio-Rad,” “we,” “us,” “the Company” and “our” refer to Bio-Rad Laboratories, Inc. and its subsidiaries.  The accompanying unaudited condensed consolidated financial statements of Bio-Rad have been prepared in accordance with accounting principles generally accepted in the United States of America (GAAP) and reflect all adjustments which are, in the opinion of management, necessary to fairly state the results of the interim periods presented.  All such adjustments are of a normal recurring nature. Results for the interim period are not necessarily indicative of the results for the entire year.  The condensed consolidated balance sheet at December 31, 2015 has been derived from the audited consolidated financial statements at that date but does not include all of the information and footnotes required by GAAP for complete financial statements. The condensed consolidated financial statements should be read in conjunction with the notes to the consolidated financial statements contained in our Annual Report on Form 10-K for the year ended December 31, 2015.

We evaluate subsequent events and the evidence they provide about conditions existing at the date of the balance sheet as well as conditions that arose after the balance sheet date but through the date the financial statements are issued.  The effects of conditions that existed at the balance sheet date are recognized in the financial statements. Events and conditions arising after the balance sheet date but before the financial statements are issued are evaluated to determine if disclosure is required to keep the financial statements from being misleading.  To the extent such events and conditions exist, disclosures are made regarding the nature of events and the estimated financial effects of those events and conditions.

Use of Estimates

The preparation of the condensed consolidated financial statements requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingencies at the date of the financial statements as well as the reported amounts of revenues and expenses during the reporting periods. Bio-Rad bases its estimates on historical experience and on various other market-specific and other relevant assumptions that are believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources. Actual results could differ materially from those estimates.

Recent Accounting Standards Updates

In October 2016, Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update No. (“ASU”) 2016-16, "Intra-Entity Transfers of Assets Other Than Inventory." ASU 2016-16 requires immediate recognition of income tax consequences of intercompany asset transfers, other than inventory transfers.  Existing GAAP prohibits recognition of income tax consequences of intercompany asset transfers whereby the seller defers any net tax effect and the buyer is prohibited from recognizing a deferred tax asset on the difference between the newly created tax basis of the asset in its tax jurisdiction and its financial statement carrying amount as reported in the consolidated financial statements.  ASU 2016-16 specifically excludes from its scope intercompany inventory transfers whereby the recognition of tax consequences will take place when the inventory is sold to third parties. ASU 2016-16 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted as of the beginning of an annual reporting period for which financial statements have not been issued or made available for issuance. We are currently evaluating the effect ASU 2016-16 will have on our consolidated financial statements.

In August 2016, FASB issued ASU 2016-15, "Classification of Certain Cash Receipts and Cash Payments." ASU 2016-15 is intended to reduce diversity in practice in how certain transactions are classified in the statement of cash flows. ASU 2016-15 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years, with early adoption permitted. We are currently evaluating the effect ASU 2016-15 will have on our consolidated statements of cash flows.

In June 2016, the FASB issued ASU 2016-13, "Measurement of Credit Losses on Financial Instruments." ASU 2016-13 will replace the current incurred loss approach with an expected loss model for instruments measured at amortized cost and require entities to record allowances for available-for-sale debt securities rather than reduce the carrying amount under the current other-than-temporary impairment model. ASU 2016-13 is effective for fiscal years beginning after December 15, 2019, and interim periods within those fiscal years. Early adoption is permitted for all entities for annual periods beginning after December 15, 2018, and interim periods therein. We are currently evaluating the effect ASU 2016-13 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-09, "Improvements to Employee Share-Based Payment Accounting." ASU 2016-09 will require all income tax effects of awards to be recognized in the income statement when the awards vest or are settled. It also will allow an employer to repurchase more of an employee’s shares than it can today for tax withholding purposes without triggering liability accounting and to make a policy election to account for forfeitures as they occur. ASU 2016-09 is effective for fiscal years beginning after December 15, 2016, and interim periods within those fiscal years and early adoption is permitted. We are currently evaluating the effect ASU 2016-09 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-07, "Simplifying the Transition to the Equity Method of Accounting," which eliminates the requirement to retrospectively apply the equity method in previous periods when an investor initially obtains significant influence over an investee. Under current guidance, an investor that doesn’t consolidate an investment and initially accounts for it under a method other than the equity method is required to retrospectively apply the equity method in prior periods in which it held the investment when it subsequently obtained significant influence. ASU 2016-07 will be applied on a prospective basis and is effective for all entities for fiscal years beginning after December 15, 2016, and interim periods within those years and early adoption is permitted. We do not plan to early adopt ASU 2016-07 and currently do not expect it to affect our consolidated financial statements when adopted on January 1, 2017.

In February 2016, the FASB issued ASU 2016-02, "Leases," which will require, among other items, lessees to recognize most leases as assets and liabilities on the balance sheet. Qualitative and quantitative disclosures will be enhanced to better understand the amount, timing and uncertainty of cash flows arising from leases. ASU 2016-02 is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years, with early adoption permitted. We do not plan to early adopt. ASU 2016-02 will be adopted on a modified retrospective basis, with elective reliefs, which requires application of ASU 2016-02 for all periods presented. We are currently evaluating the effect ASU 2016-02 will have on our consolidated financial statements.

In January 2016, the FASB issued ASU 2016-01, "Recognition and Measurement of Financial Assets and Financial Liabilities." Amendments under ASU 2016-01, among other items, require that all equity investments in unconsolidated entities (other than those accounted for using the equity method of accounting) will generally be measured at fair value through earnings. There will no longer be an available-for-sale classification, for which changes in fair value are reported in other comprehensive income, for equity securities with readily determinable fair values. For equity investments without readily determinable fair values, the cost method is also eliminated. However, entities will be able to elect to record equity investments without readily determinable fair values at cost, less impairment, and plus or minus subsequent adjustments for observable price changes. Changes in the basis of these equity investments will be reported in current earnings. ASU 2016-01 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. We are currently evaluating the effect ASU 2016-01 will have, if any, on our consolidated financial statements.

In September 2015, the FASB issued ASU 2015-16, "Simplifying the Accounting for Measurement-Period Adjustments," which eliminates the requirement for an acquirer in a business combination to account for measurement-period adjustments retrospectively. Under ASU 2015-16, acquirers must recognize measurement-period adjustments during the period in which they determine the amounts, including the effect on earnings of any amounts they would have recorded in previous periods if the accounting had been completed at the acquisition date. The measurement period cannot exceed one year from the date of the acquisition. ASU 2015-16 was effective on January 1, 2016, and we adopted it at the same time as a change in accounting policy, which had no impact on our consolidated financial statements.

In July 2015, the FASB issued ASU 2015-11, “Simplifying the Measurement of Inventory.” Under current guidance, an entity subsequently measures inventory at the lower of cost or market, with market defined as replacement cost, net realizable value (NRV), or NRV less a normal profit margin. An entity uses current replacement cost provided that it is not above NRV (i.e., the ceiling) or below NRV less an “approximately normal profit margin” (i.e., the floor). ASU 2015-11 eliminates this analysis and requires entities to measure most inventory “at the lower of cost and NRV.” ASU 2015-11 is effective prospectively for annual periods beginning after December 15, 2016, and interim periods therein, with early adoption permitted. We will not early adopt. We do not expect ASU 2015-11 to have a material impact to our consolidated financial statements when adopted on January 1, 2017.

In April 2015, the FASB issued ASU 2015-03, "Simplifying the Presentation of Debt Issuance Costs." ASU 2015-03 was issued to simplify the presentation of debt issuance costs by requiring debt issuance costs to be presented as a deduction from the corresponding debt liability. This makes the presentation of debt issuance costs consistent with the presentation of debt discounts or premiums. Under prior U.S. GAAP, debt issuance costs were reported on the balance sheet as assets and amortized as interest expense. Under ASU 2015-03, debt issuance costs will continue to be amortized to interest expense using the effective interest method. In August 2015, the FASB issued ASU 2015-15, "Presentation and Subsequent Measurement of Debt Issuance Costs Associated with Line-of-Credit Arrangements" to clarify the SEC staff’s position that it would not object to an entity deferring and presenting debt issuance costs as an asset and subsequently amortizing the deferred debt issuance costs ratably over the term of the line-of-credit arrangement, which is our current practice. We adopted ASU 2015-03 on January 1, 2016 on a retrospective basis as a change in accounting policy. The Condensed Consolidated Balance Sheet as of December 31, 2015, was retrospectively adjusted by decreasing Other assets and Long-term debt, net of current maturities by $1.8 million, respectively.

In May 2014, the FASB issued ASU 2014-09, “Revenue from Contracts with Customers,” which requires an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. ASU 2014-09 will replace most existing revenue recognition guidance in GAAP when it becomes effective. In August 2015, the FASB issued ASU 2015-14 to defer the effective date for annual reporting periods beginning after December 15, 2017, including interim periods within that reporting period. Early adoption is permitted as of the original effective date in ASU 2014-09, which is annual reporting periods beginning after December 15, 2016, however, we will not early adopt. In May 2016, the FASB issued ASU 2016-12, "Narrow-Scope Improvements and Practical Expedients," which amends and clarifies certain aspects in ASU 2014-09 that include collectiblity, presentation of sales and other taxes collected from customers, noncash consideration, contract modifications and completed contracts at transition. In April 2016, the FASB issued ASU 2016-10, "Identifying Performance Obligations and Licensing," which amends the guidance in ASU 2014-09 on accounting for licenses of intellectual property and identifying performance obligations. In March 2016, The FASB issued ASU 2016-08, "Principal versus Agent Considerations (Reporting Revenue Gross versus Net)," which amends the principal versus agent guidance in ASU 2014-09. The standards are to be applied retrospectively and permit the use of either the retrospective or cumulative effect transition method. We will use the cumulative effect transition method once we adopt ASUs 2014-09, 2016-12, 2016-10 and 2016-08 on January 1, 2018. We are currently evaluating the effect that these ASUs will have on our consolidated financial statements and related disclosures.

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2. Acquisitions

9 Months Ended

Sep. 30, 2016

Business Combinations [Abstract]

Business Combination Disclosure [Text Block]

ACQUISITIONS

Propel Labs, Inc.

In January 2016, we acquired a high performance analytical flow cytometer platform from Propel Labs (Propel) that will enable advanced and novice users to perform basic and multi-parameter cytometry for a wide range of applications and chemistries. This asset acquisition was accounted for as a business combination, as the new analytical flow cytometer platform represented an integrated set of activities and assets that is capable of being conducted and managed for the purpose of providing a return and therefore constitutes a business in accordance with GAAP. The amount of the acquisition-related cost was minimal as Bio-Rad primarily represented itself during the acquisition process. This business acquisition is included in our Life Science segment’s results of operations from the acquisition date.

The fair value of the consideration as of the acquisition date was $38.8 million, which included $9.5 million paid in cash at the closing date and $29.3 million in contingent consideration potentially payable to Propel. The contingent consideration was based on a probability-weighted income approach related to the achievement of certain sales milestones, and was recognized at its estimated fair value of $29.3 million as of September 30, 2016 (see Note 3, "Fair Value Measurements").

The final fair values of the net assets acquired from Propel as of the acquisition date were determined to be $36.0 million of definite-lived intangible assets and $2.8 million of goodwill. We expect the goodwill recorded to be deductible for income tax purposes. The acquired analytical flow cytometer platform fits well into Bio-Rad’s existing Life Science segment product offerings and may offer researchers greater access to this technology.

In addition, Bio-Rad contracted with Propel to provide development services concurrent with and included in the purchase agreement. Bio-Rad is receiving future manufacturing, engineering and marketing support from Propel on which payments will be made upon the successful completion of all contracted services. As a result, these services are not included in the total purchase consideration and a majority will be expensed in future periods.

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3. Fair Value Measurements

9 Months Ended

Sep. 30, 2016

Fair Value Disclosures [Abstract]

Fair Value Measurements

3.FAIR VALUE MEASUREMENTS

We determine the fair value of an asset or liability based on the assumptions that market participants would use in pricing the asset or liability in an orderly transaction between market participants at the measurement date.  The identification of market participant assumptions provides a basis for determining what inputs are to be used for pricing each asset or liability.  A fair value hierarchy has been established which gives precedence to fair value measurements calculated using observable inputs over those using unobservable inputs. This hierarchy prioritizes the inputs into three broad levels as follows:

• Level 1: Quoted prices in active markets for identical instruments

• Level 2: Other significant observable inputs (including quoted prices in active markets for similar instruments)

• Level 3: Significant unobservable inputs (including assumptions in determining the fair value of certain investments)

Financial assets and liabilities carried at fair value and measured on a recurring basis as of September 30, 2016 are classified in the hierarchy as follows (in millions):

	Level 1		Level 2		Level 3		Total
Financial Assets Carried at Fair Value:
Cash equivalents:
Commercial paper	$	—	$	11.6	$	—	$	11.6
Municipals	—		0.7		—		0.7
Foreign time deposits	10.3		—		—		10.3
Domestic time deposits	—		20.0		—		20.0
Money market funds	6.5		—		—		6.5
Total cash equivalents (a)	16.8		32.3		—		49.1
Restricted investment:	4.2		—		—		4.2
Available-for-sale investments:
Corporate debt securities	—		185.6		—		185.6
U.S. government sponsored agencies	—		76.8		—		76.8
Foreign government obligations	—		5.2		—		5.2
Brokered CD's	—		3.1		—		3.1
Municipal obligations	—		14.8		—		14.8
Marketable equity securities	844.5		—		—		844.5
Asset-backed securities	—		67.5		—		67.5
Total available-for-sale investments (b)	844.5		353.0		—		1,197.5
Forward foreign exchange contracts (c)	—		0.6		—		0.6
Total financial assets carried at fair value	$	865.5	$	385.9	$	—	$	1,251.4
Financial Liabilities Carried at Fair Value:
Forward foreign exchange contracts (d)	$	—	$	0.8	$	—	$	0.8
Contingent consideration (e)	—		—		42.7		42.7
Total financial liabilities carried at fair value	$	—	$	0.8	$	42.7	$	43.5

Financial assets and liabilities carried at fair value and measured on a recurring basis as of December 31, 2015 are classified in the hierarchy as follows (in millions):

	Level 1		Level 2		Level 3		Total
Financial Assets Carried at Fair Value:
Cash equivalents:
Commercial paper	$	—	$	33.2	$	—	$	33.2
Foreign government obligations	—		0.6		—		0.6
Foreign time deposits	11.9		—		—		11.9
U.S. government sponsored agencies	—		14.6		—		14.6
Money market funds	11.3		—		—		11.3
Total cash equivalents (a)	23.2		48.4		—		71.6
Restricted investment:	4.2		—		—		4.2
Available-for-sale investments:
Corporate debt securities	—		156.9		—		156.9
U.S. government sponsored agencies	—		74.8		—		74.8
Foreign government obligations	—		4.6		—		4.6
Municipal obligations	—		6.4		—		6.4
Marketable equity securities	660.1		—		—		660.1
Asset-backed securities	—		54.8		—		54.8
Total available-for-sale investments (b)	660.1		297.5		—		957.6
Forward foreign exchange contracts (c)	—		0.9		—		0.9
Total financial assets carried at fair value	$	687.5	$	346.8	$	—	$	1,034.3
Financial Liabilities Carried at Fair Value:
Forward foreign exchange contracts (d)	$	—	$	1.1	$	—	$	1.1
Contingent consideration (e)	—		—		19.1		19.1
Total financial liabilities carried at fair value	$	—	$	1.1	$	19.1	$	20.2

(a) Cash equivalents are included in Cash and cash equivalents in the Condensed Consolidated Balance Sheets.

(b) Available-for-sale investments are included in the following accounts in the Condensed Consolidated Balance Sheets (in millions):

	September 30, 2016		December 31, 2015
Short-term investments	$	388.2	$	328.7
Other investments	809.3		628.9
Total	$	1,197.5	$	957.6

(c) Forward foreign exchange contracts in an asset position are included in Other current assets in the Condensed Consolidated Balance Sheets.

(d) Forward foreign exchange contracts in a liability position are included in Other current liabilities in the Condensed Consolidated Balance Sheets.

(e) Contingent consideration liability is included in the following accounts in the Condensed Consolidated Balance Sheets (in millions):

	September 30, 2016		December 31, 2015
Other current liabilities	$	13.4	$	13.5
Other long-term liabilities	29.3		5.6
Total	$	42.7	$	19.1

In 2012, we recognized a contingent consideration liability for certain milestones of $44.6 million upon our acquisition of a new cell sorting system from Propel. Since 2012, we have paid $28.9 million upon reaching the milestones and have reduced the valuation of the milestones by $12.3 million to its estimated fair value of $3.4 million as of September 30, 2016.

During the first quarter of 2016, we recognized a contingent consideration liability upon our acquisition of a new high performance analytical flow cytometer platform from Propel. At the acquisition date, the contingent consideration was based on a probability-weighted income approach related to the achievement of sales milestones, ranging from 39% to 20% for the calendar years 2017 through 2020. The sales milestones could potentially range from $0 to an unlimited amount through December 31, 2020. The contingent consideration was recognized at its estimated fair value of $29.3 million as of September 30, 2016.

The following table provides a reconciliation of the Level 3 cell sorting system and analytical flow cytometer platform contingent consideration liabilities measured at estimated fair value based on original valuations and updated quarterly for the nine months ended September 30, 2016 (in millions):

	2016
January 1	$	9.1
Cell sorting system:
Payment of sales milestone	(3.5		)
Decrease in estimated fair value of contingent consideration included in Selling, general and administrative expense	(2.2		)
Analytical flow cytometer platform:
Acquisition of high performance analytical flow cytometer platform	29.3
September 30	$	32.7

The following table provides quantitative information about Level 3 inputs for fair value measurement of our cell sorting system and analytical flow cytometer platform contingent consideration liabilities as of September 30, 2016. Significant increases or decreases in these inputs in isolation could result in a significantly lower or higher fair value measurement.

			Range
	Valuation Technique	Unobservable Input	From		To
Cell sorting system	Probability-weighted income approach	Sales milestones:
		Credit adjusted discount rates	0.50%		N/A
		Projected volatility of growth rate	14%		N/A
		Market price of risk	1.30%		N/A
Analytical flow cytometer platform	Probability-weighted income approach	Sales milestones:
		Market price of risk	6	%
		Volatility	10	%

In 2014, we recognized a contingent consideration liability upon our acquisition of GnuBIO. The contingent consideration for the milestones was valued at $10.7 million at the acquisition date based on assumptions regarding the probability of achieving the milestones, with such amounts discounted to present value. The Level 3 contingent consideration was revalued to a fair value of $10.0 million as of September 30, 2016 and December 31, 2015.

To estimate the fair value of Level 2 debt securities as of September 30, 2016 and December 31, 2015, our primary pricing provider uses S&P Capital IQ as the primary pricing source. Our pricing process allows us to select a hierarchy of pricing sources for securities held. The chosen pricing hierarchy for our Level 2 securities, other than certificates of deposit and commercial paper, is S&P Capital IQ as the primary pricing source and then our custodian as the secondary pricing source. If S&P Capital IQ does not price a Level 2 security that we hold, then the pricing provider will utilize our custodian supplied pricing.

For commercial paper as of September 30, 2016 and December 31, 2015, pricing is determined by a straight-line calculation, starting with the purchase price on the date of purchase and increasing to par at maturity. Interest bearing certificates of deposit and commercial paper are priced at par.

Our pricing provider performs daily reasonableness testing of the S&P Capital IQ prices. Price changes of 5% or greater are investigated and resolved. In addition, we perform a quarterly testing of the S&P Capital IQ prices to custodian reported prices. Price differences outside a tolerable variance of approximately 1% are investigated and resolved.

Available-for-sale investments consist of the following (in millions):

	September 30, 2016
	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
Short-term investments:
Corporate debt securities	$	184.7	$	1.0	$	(0.1	)	$	185.6
Brokered certificates of deposit	3.1		—		—			3.1
Municipal obligations	14.7		0.1		—			14.8
Asset-backed securities	67.1		0.2		(0.1		)	67.2
U.S. government sponsored agencies	76.2		0.7		(0.1		)	76.8
Foreign government obligations	5.2		—		—			5.2
Marketable equity securities	31.8		4.0		(0.3		)	35.5
	382.8		6.0		(0.6		)	388.2
Long-term investments:
Marketable equity securities	54.5		754.5		—			809.0
Asset-backed securities	0.3		—		—			0.3
	54.8		754.5		—			809.3
Total	$	437.6	$	760.5	$	(0.6	)	$	1,197.5

	December 31, 2015
	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
Short-term investments:
Corporate debt securities	$	157.2	$	0.1	$	(0.4	)	$	156.9
Municipal obligations	6.4		—		—			6.4
Asset-backed securities	54.8		—		(0.2		)	54.6
U.S. government sponsored agencies	74.9		0.1		(0.2		)	74.8
Foreign government obligations	4.6		—		—			4.6
Marketable equity securities	29.4		2.7		(0.7		)	31.4
	327.3		2.9		(1.5		)	328.7
Long-term investments:
Marketable equity securities	54.5		574.2		—			628.7
Asset-backed securities	0.3		—		(0.1		)	0.2
	54.8		574.2		(0.1		)	628.9
Total	$	382.1	$	577.1	$	(1.6	)	$	957.6

The unrealized gains of our long-term marketable equity securities are primarily due to our investment in Sartorius AG preferred shares.

The following is a summary of investments with gross unrealized losses and the associated fair value (in millions):

	September 30, 2016		December 31, 2015
Fair value of investments in a loss position 12 months or more	$	13.2	$	10.4
Fair value of investments in a loss position less than 12 months	$	66.7	$	204.0
Gross unrealized losses for investments in a loss position 12 months or more	$	0.3	$	0.4
Gross unrealized losses for investments in a loss position less than 12 months	$	0.3	$	1.2

The unrealized losses on these securities are due to a number of factors, including changes in interest rates, changes in economic conditions and changes in market outlook for various industries, among others.  Because Bio-Rad has the ability and intent to hold these investments with unrealized losses until a recovery of fair value, or for a reasonable period of time sufficient for a forecasted recovery of fair value, which may be maturity, we do not consider these investments to be other-than-temporarily impaired at September 30, 2016 or at December 31, 2015.

As part of distributing our products, we regularly enter into intercompany transactions.  We enter into forward foreign exchange contracts to manage foreign exchange risk of future movements in foreign exchange rates that affect foreign currency denominated intercompany receivables and payables.  We do not use derivative financial instruments for speculative or trading purposes.  We do not seek hedge accounting treatment for these contracts.  As a result, these contracts, generally with maturity dates of 90 days or less and denominated primarily in currencies of industrial countries, are recorded at their fair value at each balance sheet date.  The notional principal amounts provide one measure of the transaction volume outstanding as of September 30, 2016 and do not represent the amount of Bio-Rad's exposure to loss. The estimated fair value of these contracts was derived using the spot rates from Reuters on the last business day of the quarter and the points provided by counterparties.  The resulting gains or losses offset exchange gains or losses on the related receivables and payables, both of which are included in Foreign currency exchange losses, net in the Condensed Consolidated Statements of Income.

The following is a summary of our forward foreign exchange contracts (in millions):

	September 30,
	2016
Contracts maturing in October through December 2016 to sell foreign currency:
Notional value	$	19.3
Unrealized gain	$	—
Contracts maturing in October through December 2016 to purchase foreign currency:
Notional value	$	344.9
Unrealized loss	$	(0.3	)

The following is a summary of the amortized cost and estimated fair value of our debt securities at September 30, 2016 by contractual maturity date (in millions):

	Amortized Cost		Estimated Fair Value
Mature in less than one year	$	142.4	$	142.5
Mature in one to five years	152.4		152.9
Mature in more than five years	56.5		57.6
Total	$	351.3	$	353.0

The estimated fair value of financial instruments that are not recognized at fair value in the Condensed Consolidated Balance Sheets and are included in Other investments, are presented in the table below. Fair value has been determined using significant observable inputs, including quoted prices in active markets for similar instruments.  Estimates are not necessarily indicative of the amounts that could be realized in a current market exchange as considerable judgment is required in interpreting market data used to develop estimates of fair value. The use of different market assumptions or estimation techniques could have a material effect on the estimated fair value.  Other investments include financial instruments, the majority of which have fair value based on similar, actively traded stock adjusted for various discounts, including a discount for marketability.  Long-term debt, excluding leases and current maturities, has an estimated fair value based on quoted market prices for the same or similar issues.

The estimated fair value of the financial instruments discussed above and the level of the fair value hierarchy within which the fair value measurement is categorized are as follows (in millions):

	September 30, 2016					December 31, 2015
	Carrying  Amount		Estimated  Fair  Value		Fair Value Hierarchy Level	Carrying  Amount		Estimated  Fair  Value		Fair Value Hierarchy Level
Other investments	$	88.5	$	1,084.0	2	$	86.5	$	843.2	2
Total long-term debt, excluding leases and current maturities	$	422.3	$	465.1	2	$	421.9	$	454.3	2

We own shares of ordinary voting stock of Sartorius AG (Sartorius), of Goettingen, Germany, a process technology supplier to the biotechnology, pharmaceutical, chemical and food and beverage industries.  We own over 35% of the outstanding voting shares (excluding treasury shares) of Sartorius as of September 30, 2016.  The Sartorius family trust and Sartorius family members hold a controlling interest of the outstanding voting shares. We do not have any representative or designee on Sartorius’ Board of Directors, nor do we have the ability to exercise significant influence over the operating and financial policies of Sartorius.  We account for this investment using the cost method.  The carrying value of this investment is included in Other investments in our Condensed Consolidated Balance Sheets. As the stock is thinly traded and in conjunction with the valuation method discussed above, we have classified the estimated fair value as Level 2. The Level 2 classification is appropriate given the valuation method employed, which incorporates an observable input of the fair value of the Sartorius’ actively traded preferred stock.

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4. Intangible Assets, Goodwill and Other

9 Months Ended

Sep. 30, 2016

Goodwill and Intangible Assets Disclosure [Abstract]

Goodwill and Intangible Assets Disclosure

GOODWILL AND OTHER PURCHASED INTANGIBLE ASSETS

Changes to goodwill by segment were as follows (in millions):

	Life Science			Clinical Diagnostics			Total
Balances as of January 1, 2016:
Goodwill	$	207.2		$	316.9		$	524.1
Accumulated impairment losses	(27.2		)	(1.0		)	(28.2		)
Goodwill, net	180.0			315.9			495.9
Acquisitions	2.8			—			2.8
Currency fluctuations	0.4			7.5			7.9
Balances as of September 30, 2016:
Goodwill	210.4			324.4			534.8
Accumulated impairment losses	(27.2		)	(1.0		)	(28.2		)
Goodwill, net	$	183.2		$	323.4		$	506.6

In conjunction with the purchase of certain assets from Propel in January 2016 (see Note 2, "Acquisitions"), we recorded $2.8 million of goodwill and $36.0 million of definite-lived intangible assets: $33.0 million of developed product technology and $3.0 million of covenants not to compete.

Information regarding our identifiable purchased intangible assets with definite and indefinite lives is as follows (in millions):

	September 30, 2016
	Average Remaining Life (years)	Purchase Price		Accumulated Amortization			Net Carrying Amount
Customer relationships/lists	1-9	$	88.0	$	(53.4	)	$	34.6
Know how	1-9	186.8		(138.7		)	48.1
Developed product technology	3-13	131.9		(55.9		)	76.0
Licenses	2-10	39.5		(30.3		)	9.2
Tradenames	5-8	3.7		(2.7		)	1.0
Covenants not to compete	2-10	7.9		(2.3		)	5.6
Total definite-lived intangible assets		457.8		(283.3		)	174.5
In-process research and development		46.4		—			46.4
Total purchased intangible assets		$	504.2	$	(283.3	)	$	220.9

	December 31, 2015
	Average Remaining Life (years)	Purchase Price		Accumulated Amortization			Net Carrying Amount
Customer relationships/lists	2-10	$	84.7	$	(46.8	)	$	37.9
Know how	1-10	184.0		(121.6		)	62.4
Developed product technology	4-12	101.3		(48.9		)	52.4
Licenses	3-10	39.2		(28.5		)	10.7
Tradenames	5-9	3.5		(2.4		)	1.1
Covenants not to compete	3-7	4.8		(1.7		)	3.1
Total definite-lived intangible assets		417.5		(249.9		)	167.6
In-process research and development		46.4		—			46.4
Total purchased intangible assets		$	463.9	$	(249.9	)	$	214.0

Amortization expense related to purchased intangible assets is as follows (in millions):

	Three Months Ended				Nine Months Ended
	September 30,				September 30,
	2016		2015		2016		2015
Amortization expense	$	9.5	$	9.2	$	28.5	$	27.7

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5. Product Warranty Liability

9 Months Ended

Sep. 30, 2016

Product Warranties Disclosures [Abstract]

Product Warranty Liability

5.PRODUCT WARRANTY LIABILITY

We warrant certain equipment against defects in design, materials and workmanship, generally for a period of one year.  Upon delivery of that equipment, we establish, as part of Cost of goods sold, a provision for the expected costs of such warranty based on historical experience, specific warranty terms and customer feedback.  A review is performed on a quarterly basis to assess the adequacy of our warranty accrual.

Components of the warranty accrual, included in Other current liabilities and Other long-term liabilities in the Condensed Consolidated Balance Sheets, were as follows (in millions):

January 1, 2016	$	17.4
Provision for warranty	22.0
Actual warranty costs	(21.8		)
September 30, 2016	$	17.6

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6. Long-Term Debt

9 Months Ended

Sep. 30, 2016

Debt Disclosure [Abstract]

Long-term Debt

6.    LONG-TERM DEBT

The principal components of long-term debt are as follows (in millions):

	September 30, 2016			December 31, 2015
4.875% Senior Notes due 2020 principal amount	$	425.0		$	425.0
Less unamortized discount and debt issuance costs	(2.7		)	(3.1		)
Long-term debt less unamortized discount and debt issuance costs	422.3			421.9
Capital leases and other debt	12.1			12.3
	434.4			434.2
Less current maturities	(0.3		)	(0.3		)
Long-term debt	$	434.1		$	433.9

Senior Notes due 2020

In December 2010, Bio-Rad sold $425.0 million principal amount of Senior Notes due 2020 (4.875% Notes).  The sale yielded net cash proceeds of $422.6 million at an effective rate of 4.946%.  The 4.875% Notes pay a fixed rate of interest of 4.875% per year.  We have the option to redeem any or all of the 4.875% Notes at any time at a redemption price of 100% of the principal amount (plus a specified make-whole premium as defined in the indenture governing the 4.875% Notes) and accrued and unpaid interest thereon to the redemption date.  Our obligations under the 4.875% Notes are not secured and rank equal in right of payment with all of our existing and future unsubordinated indebtedness.  Certain covenants apply at each year end to the 4.875% Notes including limitations on the following: liens, sale and leaseback transactions, mergers, consolidations or sales of assets and other covenants. There are no restrictive covenants relating to total indebtedness, interest coverage, stock repurchases, recapitalizations, dividends and distributions to shareholders or current ratios.

Credit Agreement

In June 2014, Bio-Rad entered into a $200.0 million unsecured Credit Agreement, replacing the Amended and Restated Credit Agreement of June 2010, which expired on June 21, 2014. Borrowings under the Credit Agreement are on a revolving basis and can be used to make permitted acquisitions, for working capital and for other general corporate purposes. We had no outstanding borrowings under the Credit Agreement as of September 30, 2016 or December 31, 2015, however $0.8 million was utilized for domestic standby letters of credit that reduced our borrowing availability. The Credit Agreement matures in June 2019. If we had borrowed against our Credit Agreement, the borrowing rate would have been 2.10% at September 30, 2016.

The Credit Agreement requires Bio-Rad to comply with certain financial ratios and covenants, among other things. These ratios and covenants include a leverage ratio test and an interest coverage test, as well as restrictions on our ability to declare or pay dividends, incur debt, guarantee debt, enter into transactions with affiliates, merge or consolidate, sell assets, make investments and create liens.  We were in compliance with all of these ratios and covenants as of September 30, 2016.

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7. Accumulated Other Comprehensive Income 7. Accumulated Other Comprehensive Income (Notes)

9 Months Ended

Sep. 30, 2016

Accumulated Other Comprehensive Income (Loss), Net of Tax [Abstract]

Stockholders' Equity Note Disclosure [Text Block]

7.    ACCUMULATED OTHER COMPREHENSIVE INCOME

Accumulated other comprehensive income included in our Condensed Consolidated Balance Sheets consists of the following components (in millions):

	Foreign currency translation adjustments		Foreign other post-employment benefits adjustments			Net unrealized holding gains on available-for-sale investments			Total accumulated other comprehensive income
Balances as of January 1, 2016:	$	33.7	$	(20.7	)	$	369.1		$	382.1
Other comprehensive income (loss), before reclassifications	22.9		(0.7		)	184.8			207.0
Amounts reclassified from Accumulated other comprehensive income	—		0.9			(0.6		)	0.3
Income tax effects	—		(0.2		)	(67.8		)	(68.0		)
Other comprehensive income, net of income taxes	22.9		—			116.4			139.3
Balances as of September 30, 2016:	$	56.6	$	(20.7	)	$	485.5		$	521.4

	Foreign currency translation adjustments			Foreign other post-employment benefits adjustments			Net unrealized holding gains on available-for-sale investments			Total accumulated other comprehensive income
Balances as of January 1, 2015:	$	71.2		$	(16.3	)	$	164.0		$	218.9
Other comprehensive (loss) income, before reclassifications	(10.1		)	—			269.4			259.3
Amounts reclassified from Accumulated other comprehensive income	—			0.5			(0.4		)	0.1
Income tax effects	—			—			(99.0		)	(99.0		)
Other comprehensive (loss) income, net of income taxes	(10.1		)	0.5			170.0			160.4
Balances as of September 30, 2015:	$	61.1		$	(15.8	)	$	334.0		$	379.3

The amounts reclassified out of Accumulated other comprehensive income into the Condensed Consolidated Statements of Income, with presentation location, were as follows:

	Income before taxes impact (in millions):
		Three Months Ended						Nine Months Ended
		September 30,						September 30,
Components of Comprehensive income		2016			2015			2016			2015			Location
Amortization of foreign other post-employment benefit items		$	(0.3	)	$	(0.6	)	$	(0.9	)	$	(0.5	)	Selling, general and administrative expense
Net holding gains on available-for-sale investments		$	0.1		$	0.1		$	0.6		$	0.4		Other (income) expense, net

Reclassification adjustments are calculated using the specific identification method.

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8. Earnings Per Share

9 Months Ended

Sep. 30, 2016

Earnings Per Share [Abstract]

Earnings Per Share

8.    EARNINGS PER SHARE

Basic earnings per share is computed by dividing net income attributable to Bio-Rad by the weighted average number of common shares outstanding for that period.  Diluted earnings per share takes into account the effect of dilutive instruments, such as stock options and restricted stock, and uses the average share price for the period in determining the number of potential common shares that are to be added to the weighted average number of shares outstanding.  Potential common shares are excluded from the diluted earnings per share calculation if the effect of including such securities would be anti-dilutive.

The weighted average number of common shares outstanding used to calculate basic and diluted earnings per share, and the anti-dilutive shares that are excluded from the diluted earnings per share calculation are as follows (in thousands):

	Three Months Ended		Nine Months Ended
	September 30,		September 30,
	2016	2015	2016	2015
Basic weighted average shares outstanding	29,444	29,195	29,402	29,141
Effect of potentially dilutive stock options and restricted stock awards	227	244	190	231
Diluted weighted average common shares	29,671	29,439	29,592	29,372
Anti-dilutive shares	50	44	77	112

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9. Other Income and Expenses

9 Months Ended

Sep. 30, 2016

Other Income and Expenses [Abstract]

Other Income and Other Expense Disclosure

9.    OTHER INCOME AND EXPENSE, NET

Other (income) expense, net includes the following components (in millions):

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Interest and investment income	$	(1.3	)	$	(0.7	)	$	(13.2	)	$	(8.7	)
Net realized gain on investments	(0.1		)	—			(0.6		)	(0.3		)
Other (income) expense, net	$	(1.4	)	$	(0.7	)	$	(13.8	)	$	(9.0	)

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10. Income Taxes

9 Months Ended

Sep. 30, 2016

Income Tax Disclosure [Abstract]

Income Taxes

10.    INCOME TAXES

Our effective income tax rate was 19% and 32% for the three months ended September 30, 2016 and 2015, respectively. Our effective income tax rate was 30% and 31% for the first nine months of 2016 and 2015, respectively. The effective tax rate for the third quarter and the first nine months of 2016 was lower primarily due to adjustments related to U.S. foreign tax credits. The effective tax rate for the first nine months of 2016 and 2015 included a tax benefit from the release of U.S. tax liabilities as a result of lapses of statutes of limitations.

Our foreign taxes result primarily from income earned in France and Switzerland. Many jurisdictions in which we operate including Switzerland, Russia, the U.K. and Singapore have statutory tax rates that are significantly lower than the U.S. statutory tax rate of 35%. Our effective tax rate may be impacted in the future, either favorably or unfavorably, by many factors including, but not limited to, changes to statutory tax rates, changes in tax laws or regulations, tax audits and settlements, and generation of tax credits.

Our income tax returns are audited by U.S. federal, state and foreign tax authorities. We are currently under examination by many of these tax authorities. There are differing interpretations of tax laws and regulations, and as a result, significant disputes may arise with these tax authorities involving issues of the timing and amount of deductions and allocations of income among various tax jurisdictions. We evaluate our exposures associated with our tax filing positions on a quarterly basis.

We record liabilities for unrecognized tax benefits related to uncertain tax positions. We do not believe any currently pending uncertain tax positions will have a material adverse effect on our condensed consolidated financial statements, although an adverse resolution of one or more of these uncertain tax positions in any period may have a material impact on the results of operations for that period.

As of September 30, 2016, based on the expected outcome of certain examinations or as a result of the expiration of statutes of limitations for certain jurisdictions, we believe that within the next 12 months it is reasonably possible that our previously unrecognized tax benefits could decrease by approximately $3.1 million. Substantially all such amounts will impact our effective income tax rate.

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11. Segment Information

9 Months Ended

Sep. 30, 2016

Segment Reporting [Abstract]

Segment Information

SEGMENT INFORMATION

Information regarding industry segments for the three months ended September 30, 2016 and 2015 is as follows (in millions):

		Life Science			Clinical Diagnostics		Other Operations
Segment net sales	2016	$	178.1		$	327.1	$	3.5
	2015	$	150.4		$	316.2	$	3.4
Segment net (loss) profit	2016	$	(4.4	)	$	28.4	$	0.3
	2015	$	(12.3	)	$	40.2	$	0.4

Information regarding industry segments for the nine months ended September 30, 2016 and 2015 is as follows (in millions):

		Life Science			Clinical Diagnostics		Other Operations
Segment net sales	2016	$	523.9		$	962.5	$	10.3
	2015	$	476.8		$	961.9	$	10.2
Segment net (loss) profit	2016	$	(12.9	)	$	77.0	$	0.5
	2015	$	(20.4	)	$	116.3	$	0.2

Segment results are presented in the same manner as we present our operations internally to make operating decisions and assess performance.  Net corporate operating, interest and other expense for segment results consists of receipts and expenditures that are not the primary responsibility of segment operating management and therefore are not allocated to the segments for performance assessment by our chief operating decision maker.  Interest expense is charged to segments based on the carrying amount of inventory and receivables employed by that segment.  See Note 13 for a discussion of restructuring costs. The following reconciles total segment profit to consolidated income before taxes (in millions):

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Total segment profit	$	24.3		$	28.3		$	64.6		$	96.1
Foreign currency exchange losses, net	(1.2		)	(2.2		)	(3.6		)	(8.9		)
Net corporate operating, interest and other expense not allocated to segments	(1.8		)	(1.4		)	(5.1		)	(4.6		)
Other income (expense), net	1.4			0.7			13.8			9.0
Consolidated income before income taxes	$	22.7		$	25.4		$	69.7		$	91.6

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12. Legal Proceedings

9 Months Ended

Sep. 30, 2016

Loss Contingency, Information about Litigation Matters [Abstract]

Legal Proceedings.

12.    LEGAL PROCEEDINGS

On January 23, 2015, the City of Riviera Beach General Employees’ Retirement System filed a shareholder derivative lawsuit in the Superior Court of California, Contra Costa County, against three of our current directors and one former director. We are also named as a nominal defendant. In the complaint, the plaintiff alleges that our directors breached their fiduciary duty of loyalty by failing to ensure that we had sufficient internal controls and systems for compliance with the Foreign Corrupt Practices Act ("FCPA"); that we failed to provide adequate training on the FCPA; and that based on these actions, the directors have been unjustly enriched. Purportedly seeking relief on our behalf, the plaintiff seeks an award of restitution and unspecified damages, costs and expenses (including attorneys’ fees). On April 23, 2015, we and the individual defendants filed a demurrer requesting dismissal of the complaint in this case. The demurrer was heard on August 6, 2015, and the Court granted the demurrer for failure to make a demand on our Board of Directors on August 17, 2015, but provided leave to amend. On September 4, 2015, the plaintiff filed an amended complaint and simultaneously served a litigation demand letter on our Board of Directors ("Board") via its counsel in this action. The letter demands that we investigate and bring appropriate legal action against certain individuals, including the defendants in the City of Riviera Beach case and six current and former employees. The plaintiff also moved for a temporary stay in the proceedings, purportedly to enable the Board to respond to the demand. The Board formed a Demand Review Committee to respond to the demand. On February 24, 2016, the Demand Review Committee reported to the Board that it had concluded its investigation and unanimously determined that it is not in the best interests of the Company and its stockholders to pursue litigation against any individuals named in the City of Riviera Beach’s litigation demand letter. On October 6, 2015, we and the individual defendants filed a second demurrer, seeking to dismiss the case for failure to make a timely pre-suit demand. The case was stayed pending mediation. The caption is City of Riviera Beach General Employees’ Retirement System v. Schwartz et al., Case No. C-15-00140. The lawsuit and demand letter are referred to collectively as the “California Action”.

On August 13, 2015 and August 18, 2015, respectively, each of International Brotherhood of Electrical Workers Local 38 Pension Fund and Wayne County Employees’ Retirement System filed a stockholder derivative complaint in the Delaware Court of Chancery against four of our current directors and one former director. We are named as a nominal defendant in the complaints. The complaints allege that the defendants failed to cause us to develop internal controls sufficient to ensure our compliance with the FCPA. The plaintiffs assert claims for breach of fiduciary duty and unjust enrichment and request an award of the damages we sustained as a result of the alleged violations, among other relief. The two lawsuits were consolidated on August 27, 2015.  The case was stayed pending mediation. The caption of the consolidated case is In re Bio-Rad Laboratories, Inc. Stockholder Litigation, Consol. C.A. No. 11387-VCN (Del. Ch.). The cases filed in the Delaware Court of Chancery, together with the California Action, are referred to collectively as the “Derivative Actions”.

On July 28, 2016, we signed a Term Sheet that summarizes the material terms of a proposed settlement of the Derivative Actions. The proposed settlement includes the dismissal with prejudice of all claims asserted in the Derivative Actions, an agreed-upon set of revised corporate procedures, and no monetary payment other than an

award of attorneys’ fees and costs to the plaintiffs’ counsel. The proposed settlement is subject to review and approval by the Superior Court of California for Contra Costa County. We and the other defendants do not admit any liability or fault in connection with the proposed settlement.

On May 27, 2015, our former general counsel, Sanford S. Wadler, filed a lawsuit in the U.S. District Court, Northern District of California, against us and four of our current directors and one former director. The plaintiff’s suit alleges whistleblower retaliation in violation of the Sarbanes-Oxley Act and the Dodd-Frank Act for raising FCPA-related concerns. Mr. Wadler also alleges wrongful termination in violation of public policy, non-payment of wages and waiting time penalties in violation of the California Labor Code. The plaintiff seeks back pay, compensatory damages for lost wages, earnings, retirement benefits and other employee benefits, compensation for mental pain and anguish and emotional distress, waiting time penalties, punitive damages, litigation costs (including attorneys’ fees) and reinstatement of employment. We believe this lawsuit is without merit, and on July 28, 2015 we filed a motion to dismiss the plaintiff's complaint and specifically requested dismissal of the claims alleged against us under the Dodd-Frank Act and California Labor Code 1102.5 and the claims against the directors under the Sarbanes-Oxley Act and the Dodd-Frank Act. On October 23, 2015, the District Court granted our motion with respect to the alleged violations of the Sarbanes-Oxley Act against all the director defendants except Norman Schwartz with prejudice. The Court denied our motion to dismiss the claims under the Dodd-Frank Act as against both us and the director defendants. Discovery is taking place. The parties engaged in mediation of the case on April 19, 2016 and on September 14, 2016. The mediations did not result in a settlement. The trial is scheduled to commence on January 9, 2017.

We are also party to various other claims, legal actions and complaints arising in the ordinary course of business. We cannot at this time reasonably estimate a range of exposure, if any, of the potential liability with respect to these matters. While we do not believe, at this time, that any ultimate liability resulting from any of these other matters will have a material adverse effect on our results of operations, financial position or liquidity, we cannot give any assurance regarding the ultimate outcome of these other matters and their resolution could be material to our operating results for any particular period, depending on the level of income for the period.

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13. Restructuring Costs (Notes)

9 Months Ended

Sep. 30, 2016

Restructuring Costs [Abstract]

Restructuring and Related Activities Disclosure [Text Block]

13.    RESTRUCTURING COSTS

For the three and nine months ended September 30, 2016, we recorded $(0.2) million and $11.5 million, respectively, related to restructuring actions that include the elimination or relocation of various positions. These actions are generally intended to streamline and focus our efforts and more properly align our cost structure with projected future revenue streams.

The following table summarizes the activity of our restructuring reserves for severance, including a minimal amount of $38.8 thousand for the impact of foreign currency (in millions):

	Life Science			Clinical Diagnostics			Total
Balance at December 31, 2015	$	—		$	—		$	—
Charged to expense	4.1			7.6			$	11.7
Adjustment to expense	(0.1		)	(0.1		)	$	(0.2	)
Cash payments	(0.9		)	(1.8		)	(2.7		)
Balance at September 30, 2016	$	3.1		$	5.7		$	8.8

In May, 2016, management announced that it will take certain actions in our Europe geographic region designed to better align expenses to our revenue and gross margin profile and position us for improved operating performance. These actions, aligned with creation and evolution of our organization structure and coordinated with the implementation of our global single instance ERP platform, are expected to be incurred through 2019. As a result, we recorded approximately $(0.2) million and $11.5 million in restructuring charges related to severance and other

employee benefits for the three and nine months ended September 30, 2016, respectively, of which $8.8 million is anticipated to be paid through 2019. The liability of $8.8 million as of September 30, 2016 encompassed a short-term liability of $5.8 million and a long-term liability of $3.0 million. The amounts recorded were reflected in Cost of goods sold of $0.2 million and $2.0 million, and in Selling, general and administrative expense of $(0.4) million and $9.5 million in the Condensed Consolidated Statements of Income for the three and nine months ended September 30, 2016, respectively. The amounts adjusted were primarily due to employees finding other positions within Bio-Rad or leaving prematurely.

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1. Basis of Presentation and Use of Estimates Organization, Consolidation and Presentation of Financial Statements (Policies)

9 Months Ended

Sep. 30, 2016

Organization, Consolidation and Presentation of Financial Statements [Abstract]

New Accounting Pronouncements, Policy [Policy Text Block]

In October 2016, Financial Accounting Standards Board (“FASB”) issued Accounting Standards Update No. (“ASU”) 2016-16, "Intra-Entity Transfers of Assets Other Than Inventory." ASU 2016-16 requires immediate recognition of income tax consequences of intercompany asset transfers, other than inventory transfers.  Existing GAAP prohibits recognition of income tax consequences of intercompany asset transfers whereby the seller defers any net tax effect and the buyer is prohibited from recognizing a deferred tax asset on the difference between the newly created tax basis of the asset in its tax jurisdiction and its financial statement carrying amount as reported in the consolidated financial statements.  ASU 2016-16 specifically excludes from its scope intercompany inventory transfers whereby the recognition of tax consequences will take place when the inventory is sold to third parties. ASU 2016-16 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. Early adoption is permitted as of the beginning of an annual reporting period for which financial statements have not been issued or made available for issuance. We are currently evaluating the effect ASU 2016-16 will have on our consolidated financial statements.

In August 2016, FASB issued ASU 2016-15, "Classification of Certain Cash Receipts and Cash Payments." ASU 2016-15 is intended to reduce diversity in practice in how certain transactions are classified in the statement of cash flows. ASU 2016-15 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years, with early adoption permitted. We are currently evaluating the effect ASU 2016-15 will have on our consolidated statements of cash flows.

In June 2016, the FASB issued ASU 2016-13, "Measurement of Credit Losses on Financial Instruments." ASU 2016-13 will replace the current incurred loss approach with an expected loss model for instruments measured at amortized cost and require entities to record allowances for available-for-sale debt securities rather than reduce the carrying amount under the current other-than-temporary impairment model. ASU 2016-13 is effective for fiscal years beginning after December 15, 2019, and interim periods within those fiscal years. Early adoption is permitted for all entities for annual periods beginning after December 15, 2018, and interim periods therein. We are currently evaluating the effect ASU 2016-13 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-09, "Improvements to Employee Share-Based Payment Accounting." ASU 2016-09 will require all income tax effects of awards to be recognized in the income statement when the awards vest or are settled. It also will allow an employer to repurchase more of an employee’s shares than it can today for tax withholding purposes without triggering liability accounting and to make a policy election to account for forfeitures as they occur. ASU 2016-09 is effective for fiscal years beginning after December 15, 2016, and interim periods within those fiscal years and early adoption is permitted. We are currently evaluating the effect ASU 2016-09 will have on our consolidated financial statements.

In March 2016, the FASB issued ASU 2016-07, "Simplifying the Transition to the Equity Method of Accounting," which eliminates the requirement to retrospectively apply the equity method in previous periods when an investor initially obtains significant influence over an investee. Under current guidance, an investor that doesn’t consolidate an investment and initially accounts for it under a method other than the equity method is required to retrospectively apply the equity method in prior periods in which it held the investment when it subsequently obtained significant influence. ASU 2016-07 will be applied on a prospective basis and is effective for all entities for fiscal years beginning after December 15, 2016, and interim periods within those years and early adoption is permitted. We do not plan to early adopt ASU 2016-07 and currently do not expect it to affect our consolidated financial statements when adopted on January 1, 2017.

In February 2016, the FASB issued ASU 2016-02, "Leases," which will require, among other items, lessees to recognize most leases as assets and liabilities on the balance sheet. Qualitative and quantitative disclosures will be enhanced to better understand the amount, timing and uncertainty of cash flows arising from leases. ASU 2016-02 is effective for fiscal years beginning after December 15, 2018, and interim periods within those fiscal years, with early adoption permitted. We do not plan to early adopt. ASU 2016-02 will be adopted on a modified retrospective basis, with elective reliefs, which requires application of ASU 2016-02 for all periods presented. We are currently evaluating the effect ASU 2016-02 will have on our consolidated financial statements.

In January 2016, the FASB issued ASU 2016-01, "Recognition and Measurement of Financial Assets and Financial Liabilities." Amendments under ASU 2016-01, among other items, require that all equity investments in unconsolidated entities (other than those accounted for using the equity method of accounting) will generally be measured at fair value through earnings. There will no longer be an available-for-sale classification, for which changes in fair value are reported in other comprehensive income, for equity securities with readily determinable fair values. For equity investments without readily determinable fair values, the cost method is also eliminated. However, entities will be able to elect to record equity investments without readily determinable fair values at cost, less impairment, and plus or minus subsequent adjustments for observable price changes. Changes in the basis of these equity investments will be reported in current earnings. ASU 2016-01 is effective for fiscal years beginning after December 15, 2017, and interim periods within those fiscal years. We are currently evaluating the effect ASU 2016-01 will have, if any, on our consolidated financial statements.

In September 2015, the FASB issued ASU 2015-16, "Simplifying the Accounting for Measurement-Period Adjustments," which eliminates the requirement for an acquirer in a business combination to account for measurement-period adjustments retrospectively. Under ASU 2015-16, acquirers must recognize measurement-period adjustments during the period in which they determine the amounts, including the effect on earnings of any amounts they would have recorded in previous periods if the accounting had been completed at the acquisition date. The measurement period cannot exceed one year from the date of the acquisition. ASU 2015-16 was effective on January 1, 2016, and we adopted it at the same time as a change in accounting policy, which had no impact on our consolidated financial statements.

In July 2015, the FASB issued ASU 2015-11, “Simplifying the Measurement of Inventory.” Under current guidance, an entity subsequently measures inventory at the lower of cost or market, with market defined as replacement cost, net realizable value (NRV), or NRV less a normal profit margin. An entity uses current replacement cost provided that it is not above NRV (i.e., the ceiling) or below NRV less an “approximately normal profit margin” (i.e., the floor). ASU 2015-11 eliminates this analysis and requires entities to measure most inventory “at the lower of cost and NRV.” ASU 2015-11 is effective prospectively for annual periods beginning after December 15, 2016, and interim periods therein, with early adoption permitted. We will not early adopt. We do not expect ASU 2015-11 to have a material impact to our consolidated financial statements when adopted on January 1, 2017.

In April 2015, the FASB issued ASU 2015-03, "Simplifying the Presentation of Debt Issuance Costs." ASU 2015-03 was issued to simplify the presentation of debt issuance costs by requiring debt issuance costs to be presented as a deduction from the corresponding debt liability. This makes the presentation of debt issuance costs consistent with the presentation of debt discounts or premiums. Under prior U.S. GAAP, debt issuance costs were reported on the balance sheet as assets and amortized as interest expense. Under ASU 2015-03, debt issuance costs will continue to be amortized to interest expense using the effective interest method. In August 2015, the FASB issued ASU 2015-15, "Presentation and Subsequent Measurement of Debt Issuance Costs Associated with Line-of-Credit Arrangements" to clarify the SEC staff’s position that it would not object to an entity deferring and presenting debt issuance costs as an asset and subsequently amortizing the deferred debt issuance costs ratably over the term of the line-of-credit arrangement, which is our current practice. We adopted ASU 2015-03 on January 1, 2016 on a retrospective basis as a change in accounting policy. The Condensed Consolidated Balance Sheet as of December 31, 2015, was retrospectively adjusted by decreasing Other assets and Long-term debt, net of current maturities by $1.8 million, respectively.

In May 2014, the FASB issued ASU 2014-09, “Revenue from Contracts with Customers,” which requires an entity to recognize the amount of revenue to which it expects to be entitled for the transfer of promised goods or services to customers. ASU 2014-09 will replace most existing revenue recognition guidance in GAAP when it becomes effective. In August 2015, the FASB issued ASU 2015-14 to defer the effective date for annual reporting periods beginning after December 15, 2017, including interim periods within that reporting period. Early adoption is permitted as of the original effective date in ASU 2014-09, which is annual reporting periods beginning after December 15, 2016, however, we will not early adopt. In May 2016, the FASB issued ASU 2016-12, "Narrow-Scope Improvements and Practical Expedients," which amends and clarifies certain aspects in ASU 2014-09 that include collectiblity, presentation of sales and other taxes collected from customers, noncash consideration, contract modifications and completed contracts at transition. In April 2016, the FASB issued ASU 2016-10, "Identifying Performance Obligations and Licensing," which amends the guidance in ASU 2014-09 on accounting for licenses of intellectual property and identifying performance obligations. In March 2016, The FASB issued ASU 2016-08, "Principal versus Agent Considerations (Reporting Revenue Gross versus Net)," which amends the principal versus agent guidance in ASU 2014-09. The standards are to be applied retrospectively and permit the use of either the retrospective or cumulative effect transition method. We will use the cumulative effect transition method once we adopt ASUs 2014-09, 2016-12, 2016-10 and 2016-08 on January 1, 2018. We are currently evaluating the effect that these ASUs will have on our consolidated financial statements and related disclosures.

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3. Fair Value Measurements (Tables)

9 Months Ended

Sep. 30, 2016

Fair Value Disclosures [Abstract]

Schedule of financial assets and liabilities carried at fair value on a recurring basis

Financial assets and liabilities carried at fair value and measured on a recurring basis as of September 30, 2016 are classified in the hierarchy as follows (in millions):

	Level 1		Level 2		Level 3		Total
Financial Assets Carried at Fair Value:
Cash equivalents:
Commercial paper	$	—	$	11.6	$	—	$	11.6
Municipals	—		0.7		—		0.7
Foreign time deposits	10.3		—		—		10.3
Domestic time deposits	—		20.0		—		20.0
Money market funds	6.5		—		—		6.5
Total cash equivalents (a)	16.8		32.3		—		49.1
Restricted investment:	4.2		—		—		4.2
Available-for-sale investments:
Corporate debt securities	—		185.6		—		185.6
U.S. government sponsored agencies	—		76.8		—		76.8
Foreign government obligations	—		5.2		—		5.2
Brokered CD's	—		3.1		—		3.1
Municipal obligations	—		14.8		—		14.8
Marketable equity securities	844.5		—		—		844.5
Asset-backed securities	—		67.5		—		67.5
Total available-for-sale investments (b)	844.5		353.0		—		1,197.5
Forward foreign exchange contracts (c)	—		0.6		—		0.6
Total financial assets carried at fair value	$	865.5	$	385.9	$	—	$	1,251.4
Financial Liabilities Carried at Fair Value:
Forward foreign exchange contracts (d)	$	—	$	0.8	$	—	$	0.8
Contingent consideration (e)	—		—		42.7		42.7
Total financial liabilities carried at fair value	$	—	$	0.8	$	42.7	$	43.5

Financial assets and liabilities carried at fair value and measured on a recurring basis as of December 31, 2015 are classified in the hierarchy as follows (in millions):

	Level 1		Level 2		Level 3		Total
Financial Assets Carried at Fair Value:
Cash equivalents:
Commercial paper	$	—	$	33.2	$	—	$	33.2
Foreign government obligations	—		0.6		—		0.6
Foreign time deposits	11.9		—		—		11.9
U.S. government sponsored agencies	—		14.6		—		14.6
Money market funds	11.3		—		—		11.3
Total cash equivalents (a)	23.2		48.4		—		71.6
Restricted investment:	4.2		—		—		4.2
Available-for-sale investments:
Corporate debt securities	—		156.9		—		156.9
U.S. government sponsored agencies	—		74.8		—		74.8
Foreign government obligations	—		4.6		—		4.6
Municipal obligations	—		6.4		—		6.4
Marketable equity securities	660.1		—		—		660.1
Asset-backed securities	—		54.8		—		54.8
Total available-for-sale investments (b)	660.1		297.5		—		957.6
Forward foreign exchange contracts (c)	—		0.9		—		0.9
Total financial assets carried at fair value	$	687.5	$	346.8	$	—	$	1,034.3
Financial Liabilities Carried at Fair Value:
Forward foreign exchange contracts (d)	$	—	$	1.1	$	—	$	1.1
Contingent consideration (e)	—		—		19.1		19.1
Total financial liabilities carried at fair value	$	—	$	1.1	$	19.1	$	20.2

(a) Cash equivalents are included in Cash and cash equivalents in the Condensed Consolidated Balance Sheets.

(b) Available-for-sale investments are included in the following accounts in the Condensed Consolidated Balance Sheets (in millions):

	September 30, 2016		December 31, 2015
Short-term investments	$	388.2	$	328.7
Other investments	809.3		628.9
Total	$	1,197.5	$	957.6

(c) Forward foreign exchange contracts in an asset position are included in Other current assets in the Condensed Consolidated Balance Sheets.

(d) Forward foreign exchange contracts in a liability position are included in Other current liabilities in the Condensed Consolidated Balance Sheets.

(e) Contingent consideration liability is included in the following accounts in the Condensed Consolidated Balance Sheets (in millions):

	September 30, 2016		December 31, 2015
Other current liabilities	$	13.4	$	13.5
Other long-term liabilities	29.3		5.6
Total	$	42.7	$	19.1

Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]

The following table provides a reconciliation of the Level 3 cell sorting system and analytical flow cytometer platform contingent consideration liabilities measured at estimated fair value based on original valuations and updated quarterly for the nine months ended September 30, 2016 (in millions):

	2016
January 1	$	9.1
Cell sorting system:
Payment of sales milestone	(3.5		)
Decrease in estimated fair value of contingent consideration included in Selling, general and administrative expense	(2.2		)
Analytical flow cytometer platform:
Acquisition of high performance analytical flow cytometer platform	29.3
September 30	$	32.7

Fair Value Inputs, Liabilities, Quantitative Information [Table Text Block]

The following table provides quantitative information about Level 3 inputs for fair value measurement of our cell sorting system and analytical flow cytometer platform contingent consideration liabilities as of September 30, 2016. Significant increases or decreases in these inputs in isolation could result in a significantly lower or higher fair value measurement.

			Range
	Valuation Technique	Unobservable Input	From		To
Cell sorting system	Probability-weighted income approach	Sales milestones:
		Credit adjusted discount rates	0.50%		N/A
		Projected volatility of growth rate	14%		N/A
		Market price of risk	1.30%		N/A
Analytical flow cytometer platform	Probability-weighted income approach	Sales milestones:
		Market price of risk	6	%
		Volatility	10	%

Schedule of available-for-sale investments

Available-for-sale investments consist of the following (in millions):

	September 30, 2016
	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
Short-term investments:
Corporate debt securities	$	184.7	$	1.0	$	(0.1	)	$	185.6
Brokered certificates of deposit	3.1		—		—			3.1
Municipal obligations	14.7		0.1		—			14.8
Asset-backed securities	67.1		0.2		(0.1		)	67.2
U.S. government sponsored agencies	76.2		0.7		(0.1		)	76.8
Foreign government obligations	5.2		—		—			5.2
Marketable equity securities	31.8		4.0		(0.3		)	35.5
	382.8		6.0		(0.6		)	388.2
Long-term investments:
Marketable equity securities	54.5		754.5		—			809.0
Asset-backed securities	0.3		—		—			0.3
	54.8		754.5		—			809.3
Total	$	437.6	$	760.5	$	(0.6	)	$	1,197.5

	December 31, 2015
	Amortized Cost		Unrealized Gains		Unrealized Losses			Estimated Fair Value
Short-term investments:
Corporate debt securities	$	157.2	$	0.1	$	(0.4	)	$	156.9
Municipal obligations	6.4		—		—			6.4
Asset-backed securities	54.8		—		(0.2		)	54.6
U.S. government sponsored agencies	74.9		0.1		(0.2		)	74.8
Foreign government obligations	4.6		—		—			4.6
Marketable equity securities	29.4		2.7		(0.7		)	31.4
	327.3		2.9		(1.5		)	328.7
Long-term investments:
Marketable equity securities	54.5		574.2		—			628.7
Asset-backed securities	0.3		—		(0.1		)	0.2
	54.8		574.2		(0.1		)	628.9
Total	$	382.1	$	577.1	$	(1.6	)	$	957.6

Summary of fair value of gross unrealized losses for investments with unrealized losses

The following is a summary of investments with gross unrealized losses and the associated fair value (in millions):

	September 30, 2016		December 31, 2015
Fair value of investments in a loss position 12 months or more	$	13.2	$	10.4
Fair value of investments in a loss position less than 12 months	$	66.7	$	204.0
Gross unrealized losses for investments in a loss position 12 months or more	$	0.3	$	0.4
Gross unrealized losses for investments in a loss position less than 12 months	$	0.3	$	1.2

Discussion of current derivative risk management

The following is a summary of our forward foreign exchange contracts (in millions):

	September 30,
	2016
Contracts maturing in October through December 2016 to sell foreign currency:
Notional value	$	19.3
Unrealized gain	$	—
Contracts maturing in October through December 2016 to purchase foreign currency:
Notional value	$	344.9
Unrealized loss	$	(0.3	)

Summary of amortized cost and estimated fair value of debt securities by contractual maturity date

The following is a summary of the amortized cost and estimated fair value of our debt securities at September 30, 2016 by contractual maturity date (in millions):

	Amortized Cost		Estimated Fair Value
Mature in less than one year	$	142.4	$	142.5
Mature in one to five years	152.4		152.9
Mature in more than five years	56.5		57.6
Total	$	351.3	$	353.0

Estimated fair value of financial instruments

The estimated fair value of the financial instruments discussed above and the level of the fair value hierarchy within which the fair value measurement is categorized are as follows (in millions):

	September 30, 2016					December 31, 2015
	Carrying  Amount		Estimated  Fair  Value		Fair Value Hierarchy Level	Carrying  Amount		Estimated  Fair  Value		Fair Value Hierarchy Level
Other investments	$	88.5	$	1,084.0	2	$	86.5	$	843.2	2
Total long-term debt, excluding leases and current maturities	$	422.3	$	465.1	2	$	421.9	$	454.3	2

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4. Intangible Assets, Goodwill and Other (Tables)

9 Months Ended

Sep. 30, 2016

Goodwill and Intangible Assets Disclosure [Abstract]

Changes to goodwill by segment

Changes to goodwill by segment were as follows (in millions):

	Life Science			Clinical Diagnostics			Total
Balances as of January 1, 2016:
Goodwill	$	207.2		$	316.9		$	524.1
Accumulated impairment losses	(27.2		)	(1.0		)	(28.2		)
Goodwill, net	180.0			315.9			495.9
Acquisitions	2.8			—			2.8
Currency fluctuations	0.4			7.5			7.9
Balances as of September 30, 2016:
Goodwill	210.4			324.4			534.8
Accumulated impairment losses	(27.2		)	(1.0		)	(28.2		)
Goodwill, net	$	183.2		$	323.4		$	506.6

In conjunction with the purchase of certain assets from Propel in January 2016 (see Note 2, "Acquisitions"), we recorded $2.8 million of goodwill and $36.0 million of definite-lived intangible assets: $33.0 million of developed product technology and $3.0 million of covenants not to compete.

Schedule of identifiable purchased intangible assets with definite lives

Information regarding our identifiable purchased intangible assets with definite and indefinite lives is as follows (in millions):

	September 30, 2016
	Average Remaining Life (years)	Purchase Price		Accumulated Amortization			Net Carrying Amount
Customer relationships/lists	1-9	$	88.0	$	(53.4	)	$	34.6
Know how	1-9	186.8		(138.7		)	48.1
Developed product technology	3-13	131.9		(55.9		)	76.0
Licenses	2-10	39.5		(30.3		)	9.2
Tradenames	5-8	3.7		(2.7		)	1.0
Covenants not to compete	2-10	7.9		(2.3		)	5.6
Total definite-lived intangible assets		457.8		(283.3		)	174.5
In-process research and development		46.4		—			46.4
Total purchased intangible assets		$	504.2	$	(283.3	)	$	220.9

	December 31, 2015
	Average Remaining Life (years)	Purchase Price		Accumulated Amortization			Net Carrying Amount
Customer relationships/lists	2-10	$	84.7	$	(46.8	)	$	37.9
Know how	1-10	184.0		(121.6		)	62.4
Developed product technology	4-12	101.3		(48.9		)	52.4
Licenses	3-10	39.2		(28.5		)	10.7
Tradenames	5-9	3.5		(2.4		)	1.1
Covenants not to compete	3-7	4.8		(1.7		)	3.1
Total definite-lived intangible assets		417.5		(249.9		)	167.6
In-process research and development		46.4		—			46.4
Total purchased intangible assets		$	463.9	$	(249.9	)	$	214.0

Finite-lived Intangible Assets Amortization Expense [Table Text Block]

Amortization expense related to purchased intangible assets is as follows (in millions):

	Three Months Ended				Nine Months Ended
	September 30,				September 30,
	2016		2015		2016		2015
Amortization expense	$	9.5	$	9.2	$	28.5	$	27.7

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5. Product Warranty Liability (Tables)

9 Months Ended

Sep. 30, 2016

Product Warranties Disclosures [Abstract]

Components of warranty accrual

Components of the warranty accrual, included in Other current liabilities and Other long-term liabilities in the Condensed Consolidated Balance Sheets, were as follows (in millions):

January 1, 2016	$	17.4
Provision for warranty	22.0
Actual warranty costs	(21.8		)
September 30, 2016	$	17.6

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6. Long-Term Debt (Tables)

9 Months Ended

Sep. 30, 2016

Debt Disclosure [Abstract]

Schedule of Long-term Debt Instruments [Table Text Block]

The principal components of long-term debt are as follows (in millions):

	September 30, 2016			December 31, 2015
4.875% Senior Notes due 2020 principal amount	$	425.0		$	425.0
Less unamortized discount and debt issuance costs	(2.7		)	(3.1		)
Long-term debt less unamortized discount and debt issuance costs	422.3			421.9
Capital leases and other debt	12.1			12.3
	434.4			434.2
Less current maturities	(0.3		)	(0.3		)
Long-term debt	$	434.1		$	433.9

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7. Accumulated Other Comprehensive Income 7. Accumulated Other Comprehensive Income (Tables)

9 Months Ended

Sep. 30, 2016

Reclassification Adjustment out of Accumulated Other Comprehensive Income [Line Items]

Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block]

Accumulated other comprehensive income included in our Condensed Consolidated Balance Sheets consists of the following components (in millions):

	Foreign currency translation adjustments		Foreign other post-employment benefits adjustments			Net unrealized holding gains on available-for-sale investments			Total accumulated other comprehensive income
Balances as of January 1, 2016:	$	33.7	$	(20.7	)	$	369.1		$	382.1
Other comprehensive income (loss), before reclassifications	22.9		(0.7		)	184.8			207.0
Amounts reclassified from Accumulated other comprehensive income	—		0.9			(0.6		)	0.3
Income tax effects	—		(0.2		)	(67.8		)	(68.0		)
Other comprehensive income, net of income taxes	22.9		—			116.4			139.3
Balances as of September 30, 2016:	$	56.6	$	(20.7	)	$	485.5		$	521.4

	Foreign currency translation adjustments			Foreign other post-employment benefits adjustments			Net unrealized holding gains on available-for-sale investments			Total accumulated other comprehensive income
Balances as of January 1, 2015:	$	71.2		$	(16.3	)	$	164.0		$	218.9
Other comprehensive (loss) income, before reclassifications	(10.1		)	—			269.4			259.3
Amounts reclassified from Accumulated other comprehensive income	—			0.5			(0.4		)	0.1
Income tax effects	—			—			(99.0		)	(99.0		)
Other comprehensive (loss) income, net of income taxes	(10.1		)	0.5			170.0			160.4
Balances as of September 30, 2015:	$	61.1		$	(15.8	)	$	334.0		$	379.3

Reclassification Out of Accumulated Other Comprehensive Income [Table Text Block]

The amounts reclassified out of Accumulated other comprehensive income into the Condensed Consolidated Statements of Income, with presentation location, were as follows:

	Income before taxes impact (in millions):
		Three Months Ended						Nine Months Ended
		September 30,						September 30,
Components of Comprehensive income		2016			2015			2016			2015			Location
Amortization of foreign other post-employment benefit items		$	(0.3	)	$	(0.6	)	$	(0.9	)	$	(0.5	)	Selling, general and administrative expense
Net holding gains on available-for-sale investments		$	0.1		$	0.1		$	0.6		$	0.4		Other (income) expense, net

Reclassification adjustments are calculated using the specific identification method.

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8. Earnings Per Share (Tables)

9 Months Ended

Sep. 30, 2016

Earnings Per Share [Abstract]

Schedule of weighted-average common shares outstanding used to calculate basic and diluted earnings per shares and the anti-dilutive shares

The weighted average number of common shares outstanding used to calculate basic and diluted earnings per share, and the anti-dilutive shares that are excluded from the diluted earnings per share calculation are as follows (in thousands):

	Three Months Ended		Nine Months Ended
	September 30,		September 30,
	2016	2015	2016	2015
Basic weighted average shares outstanding	29,444	29,195	29,402	29,141
Effect of potentially dilutive stock options and restricted stock awards	227	244	190	231
Diluted weighted average common shares	29,671	29,439	29,592	29,372
Anti-dilutive shares	50	44	77	112

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9. Other Income and Expenses (Tables)

9 Months Ended

Sep. 30, 2016

Other Income and Expenses [Abstract]

Schedule of other income (expense), net

Other (income) expense, net includes the following components (in millions):

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Interest and investment income	$	(1.3	)	$	(0.7	)	$	(13.2	)	$	(8.7	)
Net realized gain on investments	(0.1		)	—			(0.6		)	(0.3		)
Other (income) expense, net	$	(1.4	)	$	(0.7	)	$	(13.8	)	$	(9.0	)

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11. Segment Information (Tables)

9 Months Ended

Sep. 30, 2016

Segment Reporting [Abstract]

Information regarding industry segments

Information regarding industry segments for the three months ended September 30, 2016 and 2015 is as follows (in millions):

		Life Science			Clinical Diagnostics		Other Operations
Segment net sales	2016	$	178.1		$	327.1	$	3.5
	2015	$	150.4		$	316.2	$	3.4
Segment net (loss) profit	2016	$	(4.4	)	$	28.4	$	0.3
	2015	$	(12.3	)	$	40.2	$	0.4

Information regarding industry segments for the nine months ended September 30, 2016 and 2015 is as follows (in millions):

		Life Science			Clinical Diagnostics		Other Operations
Segment net sales	2016	$	523.9		$	962.5	$	10.3
	2015	$	476.8		$	961.9	$	10.2
Segment net (loss) profit	2016	$	(12.9	)	$	77.0	$	0.5
	2015	$	(20.4	)	$	116.3	$	0.2

Reconciliation of segment profit to consolidated income before taxes

The following reconciles total segment profit to consolidated income before taxes (in millions):

	Three Months Ended						Nine Months Ended
	September 30,						September 30,
	2016			2015			2016			2015
Total segment profit	$	24.3		$	28.3		$	64.6		$	96.1
Foreign currency exchange losses, net	(1.2		)	(2.2		)	(3.6		)	(8.9		)
Net corporate operating, interest and other expense not allocated to segments	(1.8		)	(1.4		)	(5.1		)	(4.6		)
Other income (expense), net	1.4			0.7			13.8			9.0
Consolidated income before income taxes	$	22.7		$	25.4		$	69.7		$	91.6

XML

13. Restructuring Costs (Tables)

9 Months Ended

Sep. 30, 2016

Restructuring Costs [Abstract]

Restructuring and Related Costs [Table Text Block]

The following table summarizes the activity of our restructuring reserves for severance, including a minimal amount of $38.8 thousand for the impact of foreign currency (in millions):

	Life Science			Clinical Diagnostics			Total
Balance at December 31, 2015	$	—		$	—		$	—
Charged to expense	4.1			7.6			$	11.7
Adjustment to expense	(0.1		)	(0.1		)	$	(0.2	)
Cash payments	(0.9		)	(1.8		)	(2.7		)
Balance at September 30, 2016	$	3.1		$	5.7		$	8.8

XML

1. Basis of Presentation and Use of Estimates Organization, Consolidation and Presentation of Financial Statements (Details) - USD ($) $ in Thousands	Sep. 30, 2016	Dec. 31, 2015
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Long-term debt, net of current maturities	$ 434,137	$ 433,883
Other assets	$ 63,821	64,618
Adjustments for New Accounting Pronouncement [Member]
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Long-term debt, net of current maturities		1,800
Other assets		$ 1,800

XML

2. Acquisitions (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Mar. 31, 2016	Sep. 30, 2016	Jan. 06, 2016	Dec. 31, 2015	Apr. 10, 2014
Business Acquisition [Line Items]
Goodwill		$ 506,573		$ 495,948
Goodwill, Acquired During Period		2,800
Analytical Flow Cytometer Platform [Member]
Business Acquisition [Line Items]
Business Combination, Consideration Transferred	$ 38,800
Payments to Acquire Businesses, Net of Cash Acquired	9,500
Business Combination, Contingent Consideration, Liability		29,300	$ 29,300
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Finite-Lived Intangibles			$ 36,000
Goodwill, Acquired During Period	$ 2,800
GnuBIO [Member]
Business Acquisition [Line Items]
Business Combination, Contingent Consideration, Liability		$ 10,000			$ 10,700

XML

3. Fair Value Measurements Fair Value Level Table (Details) - USD ($) $ in Millions		Sep. 30, 2016	Jan. 06, 2016	Dec. 31, 2015
Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Restricted Investments, at Fair Value		$ 4.2		$ 4.2
Available-for-sale Securities, Fair Value Disclosure	[1]	1,197.5		957.6
Forward Foreign Exchange Contracts, Asset, Fair Value Disclosure	[2]	0.6		0.9
Assets, Fair Value Disclosure		1,251.4		1,034.3
Forward Foreign Exchange Contracts, Liability, Fair Value Disclosure	[3]	0.8		1.1
Business Combination, Contingent Consideration, Liability	[4]	42.7		19.1
Liabilities, Fair Value Disclosure		43.5		20.2
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Restricted Investments, at Fair Value		4.2		4.2
Available-for-sale Securities, Fair Value Disclosure	[1]	844.5		660.1
Forward Foreign Exchange Contracts, Asset, Fair Value Disclosure	[2]	0.0		0.0
Assets, Fair Value Disclosure		865.5		687.5
Forward Foreign Exchange Contracts, Liability, Fair Value Disclosure	[3]	0.0		0.0
Business Combination, Contingent Consideration, Liability	[4]	0.0		0.0
Liabilities, Fair Value Disclosure		0.0		0.0
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Restricted Investments, at Fair Value		0.0		0.0
Available-for-sale Securities, Fair Value Disclosure	[1]	353.0		297.5
Forward Foreign Exchange Contracts, Asset, Fair Value Disclosure	[2]	0.6		0.9
Assets, Fair Value Disclosure		385.9		346.8
Forward Foreign Exchange Contracts, Liability, Fair Value Disclosure	[3]	0.8		1.1
Business Combination, Contingent Consideration, Liability	[4]	0.0		0.0
Liabilities, Fair Value Disclosure		0.8		1.1
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Restricted Investments, at Fair Value		0.0		0.0
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Forward Foreign Exchange Contracts, Asset, Fair Value Disclosure	[2]	0.0		0.0
Assets, Fair Value Disclosure		0.0		0.0
Forward Foreign Exchange Contracts, Liability, Fair Value Disclosure	[3]	0.0		0.0
Business Combination, Contingent Consideration, Liability	[4]	42.7		19.1
Liabilities, Fair Value Disclosure		42.7		19.1
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			14.6
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			0.0
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			14.6
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			0.0
Commercial Paper [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	11.6		33.2
Commercial Paper [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0		0.0
Commercial Paper [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	11.6		33.2
Commercial Paper [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0		0.0
Municipal Notes [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.7
Municipal Notes [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0
Municipal Notes [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.7
Municipal Notes [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			0.6
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			0.0
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			0.6
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]			0.0
Foreign Time Deposits [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	10.3		11.9
Foreign Time Deposits [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	10.3		11.9
Foreign Time Deposits [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0		0.0
Foreign Time Deposits [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0		0.0
Domestic time deposit [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	20.0
Domestic time deposit [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0
Domestic time deposit [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	20.0
Domestic time deposit [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0
Money Market Funds [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	6.5		11.3
Money Market Funds [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	6.5		11.3
Money Market Funds [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0		0.0
Money Market Funds [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0		0.0
Cash Equivalents [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	49.1		71.6
Cash Equivalents [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	16.8		23.2
Cash Equivalents [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	32.3		48.4
Cash Equivalents [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Cash and Cash Equivalents, Fair Value Disclosure	[5]	0.0		0.0
Brokered certificates of deposit [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	3.1
Brokered certificates of deposit [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0
Brokered certificates of deposit [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	3.1
Brokered certificates of deposit [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0
Marketable Equity Securities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	844.5		660.1
Marketable Equity Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	844.5		660.1
Marketable Equity Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Marketable Equity Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Municipal Obligations (Member) | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	14.8		6.4
Municipal Obligations (Member) | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Municipal Obligations (Member) | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	14.8		6.4
Municipal Obligations (Member) | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	5.2		4.6
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	5.2		4.6
Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Corporate Debt Securities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	185.6		156.9
Corporate Debt Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Corporate Debt Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	185.6		156.9
Corporate Debt Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	76.8		74.8
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	76.8		74.8
US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Asset-backed Securities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	67.5		54.8
Asset-backed Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Asset-backed Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	67.5		54.8
Asset-backed Securities [Member] | Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure	[1]	0.0		0.0
Other Current Liabilities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability		13.4		13.5
Other Noncurrent Liabilities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability		29.3		5.6
Short-term Investments [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		388.2		328.7
Short-term Investments [Member] | Brokered certificates of deposit [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		3.1
Short-term Investments [Member] | Marketable Equity Securities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		35.5		31.4
Short-term Investments [Member] | Municipal Obligations (Member) | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		14.8		6.4
Short-term Investments [Member] | Foreign Government Obligations [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		5.2		4.6
Short-term Investments [Member] | Corporate Debt Securities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		185.6		156.9
Short-term Investments [Member] | US Government Sponsored Agencies [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		76.8		74.8
Short-term Investments [Member] | Asset-backed Securities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		67.2		54.6
Other Investments [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Available-for-sale Securities, Fair Value Disclosure		809.3		$ 628.9
Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability		29.3	$ 29.3
Sales milestone minimum amount [Member] | Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, Low		$ 0.0

[1] Available-for-sale investments are included in the following accounts in the Condensed Consolidated Balance Sheets (in millions): September 30, 2016 December 31, 2015Short-term investments$388.2 $328.7Other investments809.3 628.9Total$1,197.5 $957.6

[2] Forward foreign exchange contracts in an asset position are included in Other current assets in the Condensed Consolidated Balance Sheets.

[3] Forward foreign exchange contracts in a liability position are included in Other current liabilities in the Condensed Consolidated Balance Sheets.

[4] Contingent consideration liability is included in the following accounts in the Condensed Consolidated Balance Sheets (in millions): September 30, 2016 December 31, 2015Other current liabilities$13.4 $13.5Other long-term liabilities29.3 5.6   Total$42.7 $19.1

[5] Cash equivalents are included in Cash and cash equivalents in the Condensed Consolidated Balance Sheets.

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3. Fair Value Measurements 3. Contingent Consideration (Details) - USD ($) $ in Millions		9 Months Ended	48 Months Ended
		Sep. 30, 2016	Sep. 30, 2016	Jan. 06, 2016	Dec. 31, 2015	Apr. 10, 2014	Sep. 30, 2012
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Measurement with Unobservable Inputs Reconciliations, Recurring Basis, Liability Value		$ 32.7	$ 32.7		$ 9.1
CellSorter [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Contingent consideration milestone payments		(3.5)	(28.9)
(Decrease) increase in fair value of contingent consideration included in SGA		(2.2)	(12.3)
Business Combination, Contingent Consideration, Liability		3.4	3.4				$ 44.6
Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability		29.3	29.3	$ 29.3
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Issuances		29.3
GnuBIO [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability		$ 10.0	$ 10.0			$ 10.7
Sales milestone percentage of annual invoices [Member] | Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Acquisition, Contingent Consideration, Potential Percentage Payout		39.00%	39.00%
Credit Adjusted Discount Rates Lower [Member] | CellSorter [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Inputs, Entity Credit Risk		0.50%
Market Price of Risk [Member] | CellSorter [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Inputs, Entity Credit Risk		1.30%
Market Price of Risk [Member] | Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Inputs, Entity Credit Risk		6.00%
Projected Volatility of Growth Rate [Member] | CellSorter [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Inputs, Entity Credit Risk		14.00%
Projected Volatility of Growth Rate [Member] | Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Inputs, Entity Credit Risk		10.00%
Sales milestone percentage of annual invoices low [Member] | Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Acquisition, Contingent Consideration, Potential Percentage Payout		20.00%	20.00%
Sales milestone minimum amount [Member] | Analytical Flow Cytometer Platform [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration Arrangements, Range of Outcomes, Value, Low		$ 0.0	$ 0.0
Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability	[1]	42.7	42.7		19.1
Other Noncurrent Liabilities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability		29.3	29.3		5.6
Other Current Liabilities [Member] | Fair Value, Measurements, Recurring [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Business Combination, Contingent Consideration, Liability		$ 13.4	$ 13.4		$ 13.5

[1] Contingent consideration liability is included in the following accounts in the Condensed Consolidated Balance Sheets (in millions): September 30, 2016 December 31, 2015Other current liabilities$13.4 $13.5Other long-term liabilities29.3 5.6   Total$42.7 $19.1

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3. Foreign Exchange Forward Contracts (Details) $ in Millions	9 Months Ended
	Sep. 30, 2016 USD ($)
Forward foreign exchange contract to sell foreign currency [Member]
Derivatives, Fair Value [Line Items]
Notional value	$ 19.3
Gain (Loss) on Foreign Currency Derivative Instruments not Designated as Hedging Instruments	0.0
Forward foreign exchange contract to purchase foreign currency [Member]
Derivatives, Fair Value [Line Items]
Notional value	344.9
Gain (Loss) on Foreign Currency Derivative Instruments not Designated as Hedging Instruments	$ (0.3)

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3. Available-for-Sale Investments (Details) - Fair Value, Measurements, Recurring [Member] - USD ($) $ in Millions		Sep. 30, 2016	Dec. 31, 2015
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		$ 437.6	$ 382.1
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		760.5	577.1
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		(0.6)	(1.6)
Estimated Fair Value	[1]	1,197.5	957.6
Corporate Debt Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value	[1]	185.6	156.9
Brokered certificates of deposit [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value	[1]	3.1
Municipal obligations [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value	[1]	14.8	6.4
Asset-backed Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value	[1]	67.5	54.8
Marketable Equity Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value	[1]	844.5	660.1
US Government Sponsored Agencies [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value	[1]	76.8	74.8
Foreign Government Obligations [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value	[1]	5.2	4.6
Other Long-term Investments [Member] | Asset-backed Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		0.3	0.3
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		0.0	0.0
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		0.0	(0.1)
Estimated Fair Value		0.3	0.2
Other Long-term Investments [Member] | Marketable Equity Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		54.5	54.5
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		754.5	574.2
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		0.0	0.0
Estimated Fair Value		809.0	628.7
Other Long-term Investments [Member] | Available-for-sale Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		54.8	54.8
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		754.5	574.2
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		0.0	(0.1)
Estimated Fair Value		809.3	628.9
Short-term Investments [Member]
Schedule of Available-for-sale Securities [Line Items]
Estimated Fair Value		388.2	328.7
Short-term Investments [Member] | Corporate Debt Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		184.7	157.2
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		1.0	0.1
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		(0.1)	(0.4)
Estimated Fair Value		185.6	156.9
Short-term Investments [Member] | Brokered certificates of deposit [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		3.1
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		0.0
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		0.0
Estimated Fair Value		3.1
Short-term Investments [Member] | Municipal obligations [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		14.7	6.4
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		0.1	0.0
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		0.0	0.0
Estimated Fair Value		14.8	6.4
Short-term Investments [Member] | Asset-backed Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		67.1	54.8
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		0.2	0.0
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		(0.1)	(0.2)
Estimated Fair Value		67.2	54.6
Short-term Investments [Member] | Marketable Equity Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		31.8	29.4
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		4.0	2.7
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		(0.3)	(0.7)
Estimated Fair Value		35.5	31.4
Short-term Investments [Member] | Available-for-sale Securities [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		382.8	327.3
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		6.0	2.9
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		(0.6)	(1.5)
Estimated Fair Value		388.2	328.7
Short-term Investments [Member] | US Government Sponsored Agencies [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		76.2	74.9
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		0.7	0.1
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		(0.1)	(0.2)
Estimated Fair Value		76.8	74.8
Short-term Investments [Member] | Foreign Government Obligations [Member]
Schedule of Available-for-sale Securities [Line Items]
Amortized Cost		5.2	4.6
Available-for-sale Securities, Accumulated Gross Unrealized Gain, before Tax		0.0	0.0
Available-for-sale Securities, Accumulated Gross Unrealized Loss, before Tax		0.0	0.0
Estimated Fair Value		$ 5.2	$ 4.6

[1] Available-for-sale investments are included in the following accounts in the Condensed Consolidated Balance Sheets (in millions): September 30, 2016 December 31, 2015Short-term investments$388.2 $328.7Other investments809.3 628.9Total$1,197.5 $957.6

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3. Amortized Cost and Fair Value of Debt Securities (Details) $ in Millions	Sep. 30, 2016 USD ($)
Fair Value Disclosures [Abstract]
Mature in less than one year	$ 142.4
Mature in one to five years	152.4
Mature in more than five years	56.5
Total Amortized Cost	351.3
Mature in less than one year	142.5
Mature in one to five years	152.9
Mature in more than five years	57.6
Estimated Fair Value	$ 353.0

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3. Fair Value and Gross Unrealized Losses with Unrealized Losses (Details) - USD ($) $ in Millions	9 Months Ended
	Sep. 30, 2016	Dec. 31, 2015
Price Change Debt Security	5.00%
Tolerable variance Level 2 debt security pricing	1.00%
Fair Value of Investments with Gross Unrealized Losses in loss position 12 months or more	$ 13.2	$ 10.4
Cost Method Investment, Percentage Owned	35.00%
Fair Value of Investments with Gross Unrealized Losses in loss position less than 12 months	$ 66.7	204.0
Available-for-sale Securities, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss	0.3	0.4
Available-for-sale Securities, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss	$ 0.3	$ 1.2

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3. Fair Value Financial Instruments (Details) - USD ($) $ in Millions	Sep. 30, 2016	Dec. 31, 2015
Carrying (Reported) Amount, Fair Value Disclosure [Member]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Other Investments	$ 88.5	$ 86.5
Total long-term debt, excluding capital leases and current maturities	422.3	421.9
Fair Value, Inputs, Level 2 [Member] | Estimate of Fair Value, Fair Value Disclosure [Member]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Other Investments	1,084.0	843.2
Total long-term debt, excluding capital leases and current maturities	$ 465.1	$ 454.3

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4. Intangible Assets, Goodwill and Other (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2016	Dec. 31, 2015
Goodwill [Line Items]
Goodwill	$ 534,800	$ 524,100
Accumulated impairment loss	(28,200)	(28,200)
Goodwill, net	506,573	495,948
Goodwill, Acquired During Period	2,800
Currency fluctuations	7,900
Life Science [Member]
Goodwill [Line Items]
Goodwill	210,400	207,200
Accumulated impairment loss	(27,200)	(27,200)
Goodwill, net	183,200	180,000
Goodwill, Acquired During Period	2,800
Currency fluctuations	400
Clinical Diagnostics [Member]
Goodwill [Line Items]
Goodwill	324,400	316,900
Accumulated impairment loss	(1,000)	(1,000)
Goodwill, net	323,400	$ 315,900
Goodwill, Acquired During Period	0
Currency fluctuations	$ 7,500

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4. Intangible Assets, Goodwill and Other Intangible Assets (Details) - USD ($) $ in Millions	3 Months Ended			9 Months Ended		12 Months Ended
	Sep. 30, 2016	Mar. 31, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015	Dec. 31, 2015
Finite-Lived Intangible Assets, Net [Abstract]
Purchase Price	$ 457.8			$ 457.8		$ 417.5
Accumulated Amortization	(283.3)			(283.3)		(249.9)
Net Carrying Amount	174.5			174.5		167.6
Amortization [Abstract]
Amortization expense	9.5		$ 9.2	28.5	$ 27.7
Intangible Assets, Gross (Excluding Goodwill)	504.2			504.2		463.9
Customer Relationships [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Purchase Price	88.0			88.0		84.7
Accumulated Amortization	(53.4)			(53.4)		(46.8)
Net Carrying Amount	34.6			34.6		37.9
Know how [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Purchase Price	186.8			186.8		184.0
Accumulated Amortization	(138.7)			(138.7)		(121.6)
Net Carrying Amount	48.1			48.1		62.4
Developed Technology Rights [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Purchase Price	131.9			131.9		101.3
Accumulated Amortization	(55.9)			(55.9)		(48.9)
Net Carrying Amount	76.0			76.0		52.4
Licensing Agreements [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Purchase Price	39.5			39.5		39.2
Accumulated Amortization	(30.3)			(30.3)		(28.5)
Net Carrying Amount	9.2			9.2		10.7
Trade Names [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Purchase Price	3.7			3.7		3.5
Accumulated Amortization	(2.7)			(2.7)		(2.4)
Net Carrying Amount	1.0			1.0		1.1
Noncompete Agreements [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Purchase Price	7.9			7.9		4.8
Accumulated Amortization	(2.3)			(2.3)		(1.7)
Net Carrying Amount	5.6			$ 5.6		$ 3.1
Minimum [Member] | Customer Relationships [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				1 year		2 years
Minimum [Member] | Know how [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				1 year		1 year
Minimum [Member] | Developed Technology Rights [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				3 years		4 years
Minimum [Member] | Licensing Agreements [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				2 years		3 years
Minimum [Member] | Trade Names [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				5 years		5 years
Minimum [Member] | Noncompete Agreements [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				2 years		3 years
Minimum [Member] | Other Intangible Assets [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				0 years		0 years
Maximum [Member] | Customer Relationships [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				9 years		10 years
Maximum [Member] | Know how [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				9 years		10 years
Maximum [Member] | Developed Technology Rights [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				13 years		12 years
Maximum [Member] | Licensing Agreements [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				10 years		10 years
Maximum [Member] | Trade Names [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				8 years		9 years
Maximum [Member] | Noncompete Agreements [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				10 years		7 years
Maximum [Member] | Other Intangible Assets [Member]
Finite-Lived Intangible Assets, Net [Abstract]
Average Remaining Life (years)				0 years		0 years
In Process Research and Development [Member]
Amortization [Abstract]
Indefinite-Lived Intangible Assets (Excluding Goodwill)	$ 46.4			$ 46.4		$ 46.4
Analytical Flow Cytometer Platform [Member] | Developed Technology Rights [Member]
Acquired Finite-Lived Intangible Assets [Line Items]
Finite-lived Intangible Assets Acquired		$ 33.0
Analytical Flow Cytometer Platform [Member] | Noncompete Agreements [Member]
Acquired Finite-Lived Intangible Assets [Line Items]
Finite-lived Intangible Assets Acquired		$ 3.0

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5. Product Warranty Liability (Details) $ in Millions	9 Months Ended
	Sep. 30, 2016 USD ($)
Movement in Standard Product Warranty Accrual [Roll Forward]
Accrual at beginning of period	$ 17.4
Provision for warranty	22.0
Actual warranty costs	(21.8)
Accrual at end of period	$ 17.6

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6. Long-Term Debt (Details) - USD ($) $ in Thousands	3 Months Ended
	Sep. 30, 2016	Dec. 31, 2015	Dec. 31, 2010
Debt Instrument [Line Items]
Debt and Capital Lease Obligations	$ 434,400	$ 434,200
Less Current Maturities	(300)	(300)
Long-term debt, net of current maturities	434,137	433,883
Unsecured Debt [Member] | Senior Notes 4.875% due 2020 [Member]
Debt Instrument [Line Items]
Unsecured Debt	425,000	425,000
Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net	$ 2,700	3,100
Debt Instrument, Interest Rate, Stated Percentage			4.875%
Debt Instrument, Redemption Price, Percentage	100.00%
Long-term debt	$ 422,300	421,900	$ 422,600
Debt Instrument, Interest Rate, Effective Percentage			4.946%
Face amount of debt sold			$ 425,000
Capital Lease Obligations [Member] | Capital Leases and Other Debt [Member]
Debt Instrument [Line Items]
Long-term Debt and Capital Lease Obligations, Including Current Maturities	12,100	$ 12,300
Line of Credit [Member]
Debt Instrument [Line Items]
Line of credit maximum borrowing capacity	200,000
Outstanding borrowings	$ 0
Line of Credit Facility, Interest Rate at Period End	2.10%
Standby Letters of Credit [Member]
Debt Instrument [Line Items]
Line of credit maximum borrowing capacity	$ 800

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7. Accumulated Other Comprehensive Income 7. Accumulated Other Comprehensive Income (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015	Dec. 31, 2015	Dec. 31, 2014
Accumulated Other Comprehensive Income (Loss) [Line Items]
Selling, general and administrative expense	$ (201,452)	$ (187,445)	$ (596,704)	$ (568,845)
Other (income) expense, net	(1,439)	(732)	(13,824)	(8,992)
Accumulated other comprehensive income	521,403		521,403		$ 382,138
Total other comprehensive income (loss) net of tax	61,842	47,333	139,265	160,435
Accumulated Translation Adjustment [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Accumulated other comprehensive income	56,600	61,100	56,600	61,100	33,700	$ 71,200
Other Comprehensive Income (Loss), before Reclassifications, before Tax			22,900	(10,100)
Reclassification from Accumulated Other Comprehensive Income, Current Period, before Tax			0	0
Other Comprehensive Income (Loss), Tax			0	0
Total other comprehensive income (loss) net of tax			22,900	(10,100)
Accumulated Defined Benefit Plans Adjustment [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Accumulated other comprehensive income	(20,700)	(15,800)	(20,700)	(15,800)	(20,700)	(16,300)
Other Comprehensive Income (Loss), before Reclassifications, before Tax			(700)	0
Reclassification from Accumulated Other Comprehensive Income, Current Period, before Tax			900	500
Other Comprehensive Income (Loss), Tax			(200)	0
Total other comprehensive income (loss) net of tax			0	500
Accumulated Defined Benefit Plans Adjustment [Member] | Reclassification Out Of Accumulated Other Comprehensive Income [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Selling, general and administrative expense	(300)	(600)	(900)	(500)
Accumulated Net Unrealized Investment Gain (Loss) [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Accumulated other comprehensive income	485,500	334,000	485,500	334,000	369,100	164,000
Other Comprehensive Income (Loss), before Reclassifications, before Tax			184,800	269,400
Reclassification from Accumulated Other Comprehensive Income, Current Period, before Tax			(600)	(400)
Other Comprehensive Income (Loss), Tax			(67,800)	(99,000)
Total other comprehensive income (loss) net of tax			116,400	170,000
Accumulated Net Unrealized Investment Gain (Loss) [Member] | Reclassification Out Of Accumulated Other Comprehensive Income [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Other (income) expense, net	(100)	(100)	(600)	(400)
Parent [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Accumulated other comprehensive income	$ 521,400	$ 379,300	521,400	379,300	$ 382,100	$ 218,900
Other Comprehensive Income (Loss), before Reclassifications, before Tax			207,000	259,300
Reclassification from Accumulated Other Comprehensive Income, Current Period, before Tax			300	100
Other Comprehensive Income (Loss), Tax			(68,000)	(99,000)
Total other comprehensive income (loss) net of tax			$ 139,300	$ 160,400

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8. Earnings Per Share (Details) - shares shares in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Basic weighted average shares outstanding	29,444	29,195	29,402	29,141
Effect of potentially dilutive stock options and restricted stock awards	227	244	190	231
Diluted weighted average common shares	29,671	29,439	29,592	29,372
Anti-dilutive shares	50	44	77	112

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9. Other Income and Expenses (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Interest and investment income	$ (1,300)	$ (700)	$ (13,200)	$ (8,700)
Net realized gain on investments	(100)	0	(600)	(300)
Other (income) expense, net	$ (1,439)	$ (732)	$ (13,824)	$ (8,992)

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10. Income Taxes (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Effective tax rate	19.00%	32.00%	30.00%	31.00%
Significant Change in Unrecognized Tax Benefits is Reasonably Possible, Amount of Unrecorded Benefit	$ 3.1		$ 3.1
U.S. Federal [Member]
Statutory Rates	35.00%	35.00%	35.00%	35.00%

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11. Segment Information (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Segment Reporting Information [Line Items]
Net sales	$ 508,745	$ 469,961	$ 1,496,719	$ 1,448,884
Income before income taxes	22,688	25,415	69,747	91,649
Life Science [Member]
Segment Reporting Information [Line Items]
Net sales	178,100	150,400	523,900	476,800
Income before income taxes	(4,400)	(12,300)	(12,900)	(20,400)
Clinical Diagnostics [Member]
Segment Reporting Information [Line Items]
Net sales	327,100	316,200	962,500	961,900
Income before income taxes	28,400	40,200	77,000	116,300
All Other Segments [Member]
Segment Reporting Information [Line Items]
Net sales	3,500	3,400	10,300	10,200
Income before income taxes	$ 300	$ 400	$ 500	$ 200

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11. Segment Profit Reconciliation (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Income before income taxes	$ 22,688	$ 25,415	$ 69,747	$ 91,649
Operating Segments [Member]
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Income before income taxes	24,300	28,300	64,600	96,100
Corporate, Non-Segment [Member]
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Income before income taxes	(1,800)	(1,400)	(5,100)	(4,600)
Foreign Currency Gain (Loss) [Member] | Segment Reconciling Items [Member]
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Income before income taxes	(1,200)	(2,200)	(3,600)	(8,900)
Other Nonoperating Income (Expense) [Member] | Segment Reconciling Items [Member]
Segment Reporting, Reconciling Item for Operating Profit (Loss) from Segment to Consolidated [Line Items]
Income before income taxes	$ 1,400	$ 700	$ 13,800	$ 9,000

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13. Restructuring Costs (Details) - USD ($)	3 Months Ended	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2016	Dec. 31, 2015
Restructuring Cost and Reserve [Line Items]
Restructuring Reserve, Translation and Other Adjustment		$ 38,800
Restructuring Reserve	$ 8,800,000	8,800,000	$ 0
Restructuring Reserve, Current	5,800,000	5,800,000
Restructuring Reserve, Noncurrent	3,000,000.0	3,000,000.0
Restructuring Charges	(200,000)	11,500,000
Restructuring Reserve, Accrual Adjustment		(200,000)
Payments for Restructuring		(2,700,000)
Cost of Goods, Total [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring Charges	200,000	2,000,000.0
Selling, General and Administrative Expenses [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring Charges	(400,000)	9,500,000
Employee Severance [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring Charges		11,700,000
Life Science [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring Reserve	3,100,000	3,100,000	0
Restructuring Charges		4,100,000
Restructuring Reserve, Accrual Adjustment		(100,000)
Payments for Restructuring		(900,000)
Clinical Diagnostics [Member]
Restructuring Cost and Reserve [Line Items]
Restructuring Reserve	$ 5,700,000	5,700,000	$ 0
Restructuring Charges		7,600,000
Restructuring Reserve, Accrual Adjustment		(100,000)
Payments for Restructuring		$ (1,800,000)