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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 mykLhu3SAx0ukFKkSGzRIQ==

<SEC-DOCUMENT>0001181431-07-069086.txt : 20071114
<SEC-HEADER>0001181431-07-069086.hdr.sgml : 20071114
<ACCEPTANCE-DATETIME>20071114164211
ACCESSION NUMBER:		0001181431-07-069086
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20071114
FILED AS OF DATE:		20071114
DATE AS OF CHANGE:		20071114

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			EnteroMedics Inc
		CENTRAL INDEX KEY:			0001371217
		STANDARD INDUSTRIAL CLASSIFICATION:	ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS [3845]
		IRS NUMBER:				000000000

	BUSINESS ADDRESS:	
		STREET 1:		2800 Patton Rd
		CITY:			St Paul
		STATE:			MN
		ZIP:			55113

	MAIL ADDRESS:	
		STREET 1:		2800 Patton Rd
		CITY:			St Paul
		STATE:			MN
		ZIP:			55113

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			LEA GREGORY S
		CENTRAL INDEX KEY:			0001218536

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33818
		FILM NUMBER:		071245630

	MAIL ADDRESS:	
		STREET 1:		C/O PEMSTAR INC
		STREET 2:		3535 TECHNOLOGY DR NW
		CITY:			ROCHESTER
		STATE:			MN
		ZIP:			55901
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>rrd177788.xml
<DESCRIPTION>LEA FORM 3
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2007-11-14</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001371217</issuerCik>
        <issuerName>EnteroMedics Inc</issuerName>
        <issuerTradingSymbol>ETRM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001218536</rptOwnerCik>
            <rptOwnerName>LEA GREGORY S</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>2800 PATTON ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>MINNEAPOLIS</rptOwnerCity>
            <rptOwnerState>MN</rptOwnerState>
            <rptOwnerZipCode>55113</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Sr Vice Pres and CFO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>No securities are held</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.46</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2007-05-21</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2017-05-21</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>137363</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Options vest 20% on date noted, 20% on one year anniversary of date and thereafter at 1/36th per month.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Greg S. Lea</signatureName>
        <signatureDate>2007-11-13</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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