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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Operating activities:    
Net loss $ (41,345) $ (2,614)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 23,227 15,945
Revaluation of common stock warrant liability to estimated fair value (75) 38
Depreciation and amortization 5,363 4,102
Amortization of right-of-use assets 1,822 1,366
Unrealized loss (gain) on long-term marketable equity securities 486 (3,090)
Revaluation of contingent consideration to estimated fair value 564 (191)
Amortization of premium on short-term marketable securities, net 540 637
Changes in operating assets and liabilities:    
Accounts receivable (10,562) (13,419)
Inventory (2,506) (5,331)
Prepaid and other assets (514) (4,203)
Operating leases liabilities, net (1,962) (951)
Accounts payable 4,486 1,559
Accrued compensation (12,290) (1,395)
Accrued and other liabilities 7,579 4,646
Refund liability - CMS advance payment 0 (20,496)
Change in deferred taxes (158) (445)
Net cash used in operating activities (25,345) (23,842)
Investing activities:    
Acquisition of business, net of cash acquired (102) (3,500)
Acquisition of intangible assets (2,100) (6,700)
Purchases of short-term marketable securities (182,913) (5,500)
Maturities of short-term marketable securities 42,984 55,080
Additions of capital expenditures, net (13,111) (4,088)
Net cash (used in) provided by investing activities (155,242) 35,292
Financing activities:    
Proceeds from issuance of common shares in public equity offering, net of issuance costs paid 0 188,755
Proceeds from issuance of common stock under employee stock purchase plan 999 838
Taxes paid related to net share settlement of restricted stock units (3,892) (8,951)
Proceeds from exercise of warrants 0 4
Proceeds from exercise of stock options 2,011 9,026
Principal payments on finance lease obligations 0 (63)
Payment of contingent consideration (250) 0
Net cash (used in) provided by financing activities (1,132) 189,609
Effect of exchange rate changes on cash, cash equivalents and restricted cash 59 (105)
Net (decrease) increase in cash, cash equivalents and restricted cash (181,660) 200,954
Cash, cash equivalents, and restricted cash at beginning of period 348,696 134,939
Cash, cash equivalents, and restricted cash at end of period $ 167,036 $ 335,893