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Derivative Financial Instruments - Warrants (Details)
$ / shares in Units, $ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2021
USD ($)
$ / shares
shares
Jun. 30, 2020
USD ($)
Jun. 30, 2021
USD ($)
$ / shares
shares
Jun. 30, 2020
USD ($)
Dec. 31, 2020
$ / shares
Changes in the Company's derivative financial instruments liability balance          
Balance of warrants outstanding at the beginning of the period (in shares) | shares     5,260,992    
Balance of warrants outstanding at the end of the period (in shares) | shares 4,490,159   4,490,159    
Balance of derivative financial instruments liability at the beginning of the period     $ 285    
Change in fair value of derivative financial instruments—warrants during the period recognized as a gain in the condensed statements of operations $ 61 $ (44) 268 $ (42)  
Balance of derivative financial instruments liability at the end of the period $ 17   $ 17    
Warrants to purchase Common Stock          
Range of assumptions used to determine the fair value of warrants          
Estimated fair value of Cardiff Oncology common stock (in dollars per share) | $ / shares $ 6.65   $ 6.65   $ 17.99
Warrants to purchase Common Stock | Black Scholes Option Pricing Method          
Changes in the Company's derivative financial instruments liability balance          
Balance of warrants outstanding at the beginning of the period (in shares) | shares     64,496    
Balance of warrants outstanding at the end of the period (in shares) | shares 64,496   64,496    
Balance of derivative financial instruments liability at the beginning of the period     $ 285    
Change in fair value of derivative financial instruments—warrants during the period recognized as a gain in the condensed statements of operations     (268)    
Balance of derivative financial instruments liability at the end of the period $ 17   $ 17    
Expected warrant term | Warrants to purchase Common Stock          
Range of assumptions used to determine the fair value of warrants          
Expected warrant term 1 year 7 months 6 days   1 year 7 months 6 days   2 years 1 month 6 days
Risk-free interest rate | Warrants to purchase Common Stock          
Range of assumptions used to determine the fair value of warrants          
Measurement input 0.0016   0.0016   0.0013
Expected volatility of Cardiff Oncology common stock | Warrants to purchase Common Stock          
Range of assumptions used to determine the fair value of warrants          
Measurement input 1.10   1.10   1.16
Dividend yield | Warrants to purchase Common Stock          
Range of assumptions used to determine the fair value of warrants          
Measurement input 0   0   0