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License and Services Agreement - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 9 Months Ended 12 Months Ended
Mar. 31, 2018
Nov. 30, 2017
Sep. 30, 2018
Dec. 31, 2017
License And Services Agreement [Line Items]        
Proceeds from capital contribution     $ 12,000  
January 2017 Notes        
License And Services Agreement [Line Items]        
Repay an outstanding convertible note $ 4,000      
VX3 License Agreement        
License And Services Agreement [Line Items]        
Research and development, milestone payments to company   $ 32,000    
Terms of license agreement upon termination     the Company will issue to VX3 or its designees the number of shares of the Company’s common stock equal to the lesser of (1) the aggregate of all payments made to VX3 by the Canadian investors divided by $18.20 and (2) the then fair market value of VX3 divided by the then fair market value of one share of the Company’s common stock.  
Base amount to determine issuance of common stock upon termination   $ 18.20    
Services Agreement        
License And Services Agreement [Line Items]        
Services payments received       $ 11,900
VX3        
License And Services Agreement [Line Items]        
Percentage of voting interest     90.00% 96.00%
Proceeds from capital contribution     $ 12,000