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Balance Sheets Details (Property and Equipment) (Details) (USD $)
In Thousands, unless otherwise specified |
Mar. 31, 2014
|
Dec. 31, 2013
|
|---|---|---|
| Property, Plant and Equipment [Line Items] | ||
| Property and equipment, gross | $ 37,066 | $ 37,866 |
| Less: accumulated depreciation and amortization | (29,678) | (29,461) |
| Property and equipment, net, excluding construction in progress | 7,388 | 8,405 |
| Property and equipment, net | 7,396 | 8,446 |
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Laboratory equipment [Member]
|
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| Property, Plant and Equipment [Line Items] | ||
| Property and equipment, gross | 23,136 | 23,949 |
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Leasehold Improvements [Member]
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||
| Property, Plant and Equipment [Line Items] | ||
| Property and equipment, gross | 9,493 | 9,493 |
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Computer equipment [Member]
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||
| Property, Plant and Equipment [Line Items] | ||
| Property and equipment, gross | 3,209 | 3,196 |
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Office equipment and furniture [Member]
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||
| Property, Plant and Equipment [Line Items] | ||
| Property and equipment, gross | 1,228 | 1,228 |
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Construction in Progress [Member]
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| Property, Plant and Equipment [Line Items] | ||
| Property and equipment, gross | $ 8 | $ 41 |