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Summary of Significant Accounting Policies - Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share (Details) - shares
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Shares Underlying Options Outstanding [Member]    
Excluded anti-dilutive stock options and warrants 7,434,561 6,770,777
Shares Underlying Warrants Outstanding [Member]    
Excluded anti-dilutive stock options and warrants 6,642,344 7,099,010
Unvested Restricted Stock [Member]    
Excluded anti-dilutive stock options and warrants 449,043 799,387