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Stock Plans, Share-Based Payments and Warrants (Details Narrative) - USD ($)
12 Months Ended
Dec. 23, 2015
Sep. 29, 2015
Mar. 21, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 18, 2015
Nov. 10, 2014
Jan. 07, 2014
Dec. 31, 2013
Mar. 10, 2011
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Options outstanding       4,303,638 2,472,234       2,410,134  
Stock options granted       2,911,829 352,519          
Share-based compensation expense       $ 328,000 $ 421,000          
Fair value of options vested       $ 234,000 $ 507,000          
Weighted-average fair value of options granted       $ 0.56 $ 0.45          
Share-based compensation arrangement by share-based payment award, options, outstanding, intrinsic value       $ 0 $ 241,000          
Share-based compensation arrangement by share-based payment award, options, vested and expected to vest, outstanding, aggregate intrinsic value       $ 0 $ 235,000          
Share-based compensation arrangement by share-based payment award, options, vested and expected to vest, outstanding, weighted average remaining contractual term       8 years 6 months 7 years 6 months          
Employee service share-based compensation, nonvested awards, compensation not yet recognized, stock options       $ 1,174,000            
Employee service share-based compensation, nonvested awards, compensation cost not yet recognized, period for recognition       3 years 6 months            
Employee service share-based compensation, nonvested awards, compensation recognized at the time of certain performance conditions met       $ 158,000            
Class of warrant or right exercise price       $ 0.57 $ 0.33   $ 0.60 $ 0.30    
Stock based compensation recognized amortization cost       $ 1,016,000            
Class of warrant or right, number of securities called by warrants or rights           5,008,689        
Warrants exercised       2,451,000 $ 15,000          
Deemed dividend       $ 73,000            
Additional shares not issued results of warrants exercised       30 9          
Warrants exercised         791,278          
Stock issued during period, shares, new issues     7,140,823   36,570          
Lambda Warrants [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Class of warrant or right, number of securities called by warrants or rights   2,127                
Warrants exercised   $ 851                
Restricted Stock [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock options granted       617,795 132,077          
Share-based compensation expense       $ 161,000 $ 109,000          
Weighted-average fair value of options granted       $ 0.48 $ 0.86          
Employee service share-based compensation, nonvested awards, compensation not yet recognized, stock options       $ 39,000            
Employee service share-based compensation, nonvested awards, compensation cost not yet recognized, period for recognition       6 months            
Rights Offering Warrants [Member] | Investor [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Class of warrant or right exercise price                   $ 0.40
Class of warrant or right, number of securities called by warrants or rights                   2,226,112
Rights Offering Warrants [Member] | Lambda Warrants [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Class of warrant or right exercise price                   $ 0.40
Class of warrant or right, number of securities called by warrants or rights                   2,782,577
2011 Warrants [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Class of warrant or right, number of securities called by warrants or rights 3,442,521                  
Gross proceeds from warrants exercise $ 688,000                  
Warrants exercised under cashless exercise provision       $ 0.20            
Class of warrant or right, date from which warrants or rights exercisable       Dec. 18, 2015            
Warrants exercised       $ 0            
2015 Equity Incentive Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Number of shares reserved and authorized for awards       7,000,000            
Options expire date       Aug. 14, 2025            
2015 Equity Incentive Plan [Member] | Employee Stock Option [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Options outstanding       2,795,693            
Stock option plan terms and description       The options issued to employees expire on various dates between May 7, 2025 and December 17, 2025            
Shares available for future grants       3,470,376            
Stock option vesting term description       Options currently outstanding are fully vested or will vest upon a combination of the following: immediate vesting, performance-based vesting or straight line vesting of two or four years.            
Stock options granted       2,795,693            
Stock options will vest upon the specified performance condition is met       327,629            
2015 Equity Incentive Plan [Member] | Employee Stock Option [Member] | Option and Resteicted Stock [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Shares available for future grants       3,470,376            
2015 Equity Incentive Plan [Member] | Non Employee Stock Options [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Options outstanding       116,136            
2015 Equity Incentive Plan [Member] | Maximum [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Stock options contractual term       10 years            
2004 Stock Incentive Plan [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Shares available for future grants         2,054,799          
2004 Stock Incentive Plan [Member] | Non Employee Stock Options [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Options outstanding         903,709          
Stock option plan terms and description         options expire at various dates between April 26, 2015 and November 17, 2024, and vest upon a combination of the following: immediate vesting or straight line vesting of two or four years.          
2004 Stock Incentive Plan [Member] | Employee Stock Option [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Options outstanding       488,600 1,236,975          
Stock option plan terms and description       The options expire on various dates between January 5, 2016 and February 5, 2024 The options expire on various dates between April 27, 2015 and February 5, 2024, and have vested or will vest upon a combination of the following: immediate vesting or straight line vesting of two or four years.          
2004 Stock Incentive Plan [Member] | Non Employee Stock Options [Member]                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                    
Options outstanding       903,209            
Stock option plan terms and description       options expire at various dates between January 5, 2016 and November 17, 2024