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Equity Incentive Plans and Stock Based Compensation - Weighted-Average Fair Value Valuation Assumptions (Detail) - Employee Stock Options - $ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]    
Risk-free interest rate 0.93% 1.44%
Expected term (in years) 6 years 29 days 6 years 29 days
Dividend yield 0.00% 0.00%
Volatility 113.25% 110.90%
Weighted-average fair value of stock options granted $ 10.81 $ 11.75