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Balance Sheet Components - Components of Accrued Liabilities (Detail) - USD ($)
$ in Thousands
Dec. 31, 2021
Dec. 31, 2020
Accrued Liabilities Current [Abstract]    
General and administrative $ 794 $ 1,577
Clinical trial related costs 1,134 1,743
Non-clinical research and manufacturing operations 2,153 4,321
Payroll related 5,388 4,908
Other accrued expenses 46 26
Total Accrued liabilities $ 9,515 $ 12,575