Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 235,639	$ 245,197
Investments in marketable securities	151,202	237,299
Accounts receivable	52,556	52,672
Inventories	20,879	26,818
Prepaid expenses and other current assets	37,367	34,848
Total current assets	497,643	596,834
Operating lease right-of-use assets, net	30,447	20,586
Property and equipment, less accumulated depreciation of $22,188 and $19,882 at June 30, 2022 and December 31, 2021, respectively	33,657	42,496
In-process research & development	23,000	23,000
Goodwill	197,797	197,797
Other non-current assets	18,045	24,427
Total Assets	800,589	905,140
Current liabilities:
Accounts payable	23,113	21,513
Accrued expenses and other current liabilities	114,703	98,153
Contingent consideration payable	19,266	18,900
Operating lease liabilities	7,543	7,409
Total current liabilities	164,625	145,975
Long-term debt	390,652	389,357
Operating lease liabilities	52,844	43,363
Deferred reimbursements	5,906	5,906
Deferred income taxes	4,930	4,930
Other non-current liabilities	8,207	8,240
Total liabilities	627,164	597,771
Commitments and contingencies
Stockholders’ equity:
Common stock, $0.01 par value, 500,000,000 shares authorized, 280,456,667 and 278,912,800 shares issued and outstanding at June 30, 2022 and December 31, 2021, respectively	2,811	2,808
Additional paid-in capital	2,631,110	2,595,419
Accumulated other comprehensive (loss) gain:
Foreign currency translation adjustment	(16,603)	5,251
Unrealized loss on available-for-sale securities	(637)	(270)
Warrants	83	83
Accumulated deficit	(2,443,339)	(2,295,922)
Total stockholders’ equity	173,425	307,369
Total Liabilities and Stockholders’ Equity	$ 800,589	$ 905,140