Consolidated Statements of Operations (Unaudited) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Revenue:
Net product sales	$ 79,545	$ 67,437	$ 223,360	$ 190,315
Cost of goods sold	11,696	8,399	26,615	21,627
Gross profit	67,849	59,038	196,745	168,688
Operating expenses:
Research and development	59,333	70,419	186,453	229,150
Selling, general, and administrative	46,107	37,850	135,109	112,722
Changes in fair value of contingent consideration payable	3,288	1,034	4,780	2,680
Depreciation and amortization	1,520	2,496	4,691	6,299
Total operating expenses	110,248	111,799	331,033	350,851
Loss from operations	(42,399)	(52,761)	(134,288)	(182,163)
Other income (expense):
Interest income	108	518	323	2,898
Interest expense	(8,165)	(6,784)	(24,307)	(14,148)
Loss on extinguishment of debt	(257)	(7,276)	(257)	(7,276)
Other income (expense)	237	3,019	(2,729)	29
Loss before income tax	(50,476)	(63,284)	(161,258)	(200,660)
Income tax benefit (expense)	182	(727)	(5,925)	(4,791)
Net loss attributable to common stockholders	$ (50,294)	$ (64,011)	$ (167,183)	$ (205,451)
Net loss attributable to common stockholders per common share - basic (in dollars per share)	$ (0.19)	$ (0.25)	$ (0.63)	$ (0.80)
Net loss attributable to common stockholders per common share — diluted (in dollars per share)	$ (0.19)	$ (0.25)	$ (0.63)	$ (0.80)
Weighted average common shares outstanding - basic (in shares)	267,464,637	259,161,799	266,085,788	258,091,170
Weighted average number of shares outstanding - diluted (in shares)	267,464,637	259,161,799	266,085,788	258,091,170