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Regulus - Additional Information (Detail) (USD $)
1 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2009
Dec. 31, 2012
Dec. 31, 2012
Dec. 31, 2014
Sep. 30, 2012
Schedule Of Equity Method Investments Joint Ventures [Line Items]          
Company ownership percentage       12.00%us-gaap_EquityMethodInvestmentOwnershipPercentage 44.00%us-gaap_EquityMethodInvestmentOwnershipPercentage
Equity method investments $ 10,000,000us-gaap_SaleOfStockConsiderationReceivedPerTransaction        
Company ownership percentage   17.00%alny_EquityInvestmentsOtherThanEquityMethodOwnershipPercentage      
Gain on issuance of stock by Regulus Therapeutics Inc.     16,084,000us-gaap_GainLossOnSaleOfPreviouslyUnissuedStockBySubsidiaryOrEquityInvesteeNonoperatingIncome    
Carrying value in Regulus Therapeutics Inc.   12,400,000alny_CarryingValueInEquitySecurities 12,400,000alny_CarryingValueInEquitySecurities 11,900,000alny_CarryingValueInEquitySecurities  
Unrealized gain in other comprehensive income   15,700,000us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax 15,700,000us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax    
Intraperiod tax benefit     (10,600,000)us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax    
Isis          
Schedule Of Equity Method Investments Joint Ventures [Line Items]          
Equity method investments $ 10,000,000us-gaap_SaleOfStockConsiderationReceivedPerTransaction
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