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Stock-based Compensation (Tables)
6 Months Ended
Jun. 30, 2018
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Schedule of Share-based Compensation, Stock Options, Activity

The activity for the 2009 Stock Option Plan, 2014 Plan and 2015 Plan for the six months ended June 30, 2018, is summarized as follows:

 

 

Number of

Shares

 

 

Weighted-

Average

Exercise

Price

 

 

Weighted-

Average

Remaining

Contractual

Life (in years)

 

 

Aggregate

Intrinsic

Value ($000)

 

Outstanding — January 1, 2018

 

 

3,075,994

 

 

$

5.59

 

 

 

7.23

 

 

$

151

 

Granted

 

 

1,148,129

 

 

$

1.75

 

 

 

 

 

 

 

 

 

Exercised

 

 

 

 

$

 

 

 

 

 

 

 

 

 

Forfeited/Cancelled

 

 

(147,708

)

 

$

7.63

 

 

 

 

 

 

 

 

 

Outstanding — June 30, 2018

 

 

4,076,415

 

 

$

4.43

 

 

 

7.66

 

 

$

12

 

Exercisable — June 30, 2018

 

 

1,958,226

 

 

$

6.27

 

 

 

6.28

 

 

$

10

 

Vested or expected to vest — June 30, 2018

 

 

4,076,415

 

 

$

4.43

 

 

 

7.66

 

 

$

12

 

Restricted stock unit ("RSU") activity under the 2014 Plan for the six months ended June 30, 2018, is summarized as follows:

 

 

Number of

Shares

 

 

Weighted

Average

Grant Date

Fair Value

Per Share

 

Non-vested at December 31, 2017

 

 

64,365

 

 

$

2.70

 

Granted

 

 

53,000

 

 

$

1.68

 

Vested

 

 

(10,701

)

 

$

3.01

 

Forfeited/Cancelled

 

 

(5,239

)

 

$

3.02

 

Non-vested at June 30, 2018

 

 

101,425

 

 

$

2.12

 

 

Stock-Based Compensation Expense Related to Stock Options

Stock-based compensation expense related to stock options is included in the following line items in the accompanying statements of operations (in thousands):

 

 

Three Months Ended June 30,

 

 

Six Months Ended June 30,

 

 

 

2018

 

 

2017

 

 

2018

 

 

2017

 

Research and development

 

$

129

 

 

$

119

 

 

$

237

 

 

$

213

 

Selling, general and administrative

 

 

339

 

 

 

319

 

 

 

656

 

 

 

620

 

Total

 

$

468

 

 

$

438

 

 

$

893

 

 

$

833