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Description of Business and Basis of Preparation (Details) - USD ($)
3 Months Ended
Sep. 30, 2016
Jun. 21, 2016
Apr. 10, 2016
Nov. 16, 2015
Mar. 31, 2017
Dec. 31, 2016
Jul. 31, 2006
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Number of warrants issued to purchase common stock (in shares)         14,033 14,033  
Net proceeds from the June 2016 Public Offering         $ 3,170,000    
Term Loan | Secured Debt              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Loan agreement term 48 months            
Term loan, face amount $ 15,000,000            
June 2016 Public Offering              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Common stock issued under Shelf Registration, net of expenses (in shares)   9,375,000          
Number of warrants issued to purchase common stock (in shares)   4,218,750          
Share price (in dollars per share)   $ 2.40          
Exercise price of warrants (in dollars per share)   $ 3.00          
Net proceeds from the June 2016 Public Offering   $ 20,800,000          
Underwriting discounts and commissions and offering expenses   $ 1,700,000          
Common Stock              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Shelf registration maximum equity offering price       $ 150,000,000      
Number of warrants issued to purchase common stock (in shares)             14,033
Exercise price of warrants (in dollars per share)             $ 45.61
Common Stock | Sales Agreement              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Shelf registration maximum equity offering price     $ 40,000,000 $ 40,000,000