Stockholders' Equity (Tables)

12 Months Ended

Dec. 31, 2022

Equity [Abstract]

Common Stock Reserved For Future Issuances

The Company had reserved shares of common stock for future issuance as follows:

	December 31,
	2022		2021
Outstanding stock options		1,740,308		1,542,126
Outstanding restricted stock units		633,270		133,834
Warrants to purchase common stock associated with March 2018 public offering - Series 2		798,810		798,810
Warrants to purchase common stock associated with December 2020 public offering - Series 2		6,800,000		6,800,000
Prefunded warrants to purchase common stock associated with December 2020 public offering		3,200,000		3,200,000
Warrants to purchase common stock associated with April 2022 Public Offering		15,000,000		—
Prefunded warrants to purchase common stock associated with April 2022 Public Offering		11,666,667		—
Warrants to purchase common stock associated with Loan Agreement		198,811		170,410
Warrants to purchase common stock associated with Danforth		50,000		50,000
For possible future issuance for the conversion of the March 2019 Notes		1,138,200		1,138,200
For possible future issuance under 2014 Plan (Note 13)		712,020		295,220
For possible future issuance under employee stock purchase plan		—		3,893
For possible future issuance under 2015 Plan (Note 13)		550,964		235,000
Total common shares reserved for future issuance		42,489,050		14,367,493