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Basis of Presentation - Additional Information (Detail) - USD ($)
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Dec. 31, 2017
Organization, Consolidation and Presentation of Financial Statements [Abstract]      
Revenues $ 0    
Net loss 2,119,397 $ 1,982,696  
Cash used in operations 1,366,650 $ 1,900,495  
Accumulated deficit $ 103,578,864   $ 101,400,797