Exhibit 32.1

CERTIFICATION

I, Ramón M. Ruiz-Comas, President and Chief Executive Officer of Triple-S Management Corporation (the Corporation), certify, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, 18 U.S.C. Section 1350, that:

1.	The Quarterly Report on Form 10-Q of the Corporation for the period ended September 30, 2008 (the Report) fully complies with the requirements of Section 13(a) or 15(d) of the Securities and Exchange Act of 1934 and;
2.	The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Corporation.

Date: October 30, 2008	By:	/s/ Ramón M. Ruiz-Comas
		Ramón M. Ruiz-Comas
		President and Chief Executive Officer

A signed original of this written statement required by Section 906 has been provided to the Corporation and will be retained by the Corporation and furnished to the Securities and Exchange Commission or its staff upon request.