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Property and Equipment - Composition of Property and Equipment, Net (Details) - USD ($)
$ in Thousands
Mar. 31, 2019
Dec. 31, 2018
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 2,196 $ 2,140
Less accumulated depreciation (1,816) (1,785)
Property and equipment, net 380 355
Lab Equipment    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 1,781 1,764
Computer Hardware, Software and Telephone    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 253 228
Furniture and Fixtures    
Property Plant And Equipment [Line Items]    
Property and equipment, gross 98 98
Leasehold Improvements    
Property Plant And Equipment [Line Items]    
Property and equipment, gross $ 64 $ 50