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Stock-Based Compensation (Tables)
12 Months Ended
Dec. 31, 2018
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Summary of Stock Option Activity

The following table summarizes stock option activity for the 2002 Plan and 2018 Plan for the year ended December 31, 2018:

 

 

 

 

 

 

 

Weighted-

 

 

Weighted-

 

 

 

 

 

 

 

 

 

 

 

Average

 

 

Average

 

 

 

 

 

 

 

 

 

 

 

Exercise

 

 

Remaining

 

 

Aggregate

 

 

 

Total

 

 

Price Per

 

 

Contractual

 

 

Intrinsic

 

 

 

Options

 

 

Share

 

 

Term (in years)

 

 

Value

 

Outstanding at Ended December 31, 2016

 

 

1,001,546

 

 

$

1.62

 

 

 

8.1

 

 

$

58,619

 

Granted

 

 

99,866

 

 

$

1.44

 

 

 

 

 

 

 

 

 

Exercised

 

 

(2,547

)

 

$

1.20

 

 

 

 

 

 

 

 

 

Cancelled or expired

 

 

(23,656

)

 

$

1.76

 

 

 

 

 

 

 

 

 

Outstanding at December 31, 2017

 

 

1,075,209

 

 

$

1.60

 

 

 

7.3

 

 

$

711,328

 

Granted

 

 

563,268

 

 

$

4.07

 

 

 

 

 

 

 

 

 

Exercised

 

 

(43,687

)

 

$

2.12

 

 

 

 

 

 

 

 

 

Cancelled or expired

 

 

(49,387

)

 

$

1.65

 

 

 

 

 

 

 

 

 

Outstanding at December 31, 2018

 

 

1,545,403

 

 

$

2.48

 

 

 

7.6

 

 

$

1,593,487

 

Vested and expected to vest at December 31, 2018

 

 

1,545,403

 

 

$

2.48

 

 

 

7.6

 

 

$

1,593,487

 

Vested and exercisable at December 31, 2018

 

 

801,294

 

 

$

1.65

 

 

 

6.3

 

 

$

1,175,200

 

Estimated Fair Value of Option on Grant Date using Weighted Average Assumptions

The fair value of each option was estimated on the date of grant using the weighted average assumptions in the table below:

 

 

 

Year Ended

 

 

 

December 31,

 

 

 

2018

 

 

2017

 

Risk-free interest rate

 

 

2.88

%

 

 

2.88

%

Expected term (in years)

 

7.0

 

 

7.1

 

Expected volatility

 

 

69

%

 

 

68

%

Expected dividend yield

 

 

 

 

 

 

Estimated fair value of common stock

 

$

4.07

 

 

$

1.00

 

Stock-based Compensation Expense

Stock-based compensation expense has been reported in the Company’s statements of operations for the years ended December 31, 2018 and 2017 as follows (in thousands):

 

 

 

Year Ended

 

 

 

December 31,

 

 

 

2018

 

 

2017

 

General and administrative

 

$

208

 

 

$

40

 

Research and development

 

 

124

 

 

 

37

 

Total stock-based compensation

 

$

332

 

 

$

77