CONDENSED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Operating activities
Net loss	$ (11,141)	$ (27,358)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	601	474
Stock-based compensation	597	670
(Gain)/loss from remeasurement of development derivative liability	(7,233)	1,426
Non-cash interest expense	45	93
Non-cash research and development expense	3,334	11,798
Changes in operating assets and liabilities:
Prepaid expenses and other assets	(1,900)	965
Accounts payable	(5,811)	2,199
Accrued expenses and other current liabilities	(1,259)	(467)
Deferred sublicense revenue	(117)	0
Net cash used in operating activities	(22,884)	(10,200)
Investing activities
Purchases of property and equipment	(49)	(133)
Net cash used in investing activities	(49)	(133)
Financing activities
Proceeds from issuance of common stock in public offering, net	1,185	60,536
Proceeds from exercise of stock options	0	2
Repayments of long-term debt	(1,364)	(1,364)
Net cash (used in)/provided by financing activities	(179)	59,174
Net (decrease)/increase in cash and cash equivalents	(23,112)	48,841
Cash and cash equivalents at the beginning of the period	41,800	28,122
Cash and cash equivalents at the end of the period	18,688	76,963
Supplemental disclosure for cash flow
Cash paid for interest	104	192
Supplemental disclosure of non-cash investing and financing activities
Stock offering costs included in accounts payable and accrued expenses	0	370
Purchases of property and equipment by incurring development derivative liability	0	3,317
Purchases of property and equipment included in accounts payable and accrued expenses	$ 36	$ 969