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The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

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Licenses and Other Agreements - Additional Information (Details) - USD ($)	1 Months Ended				3 Months Ended		9 Months Ended
	Jul. 31, 2021	Jun. 30, 2021	Jan. 31, 2020	Nov. 30, 2017	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Mar. 31, 2021
License Agreements [Line Items]
Research and development					$ 25,066,000	$ 17,416,000	$ 74,752,000	$ 49,721,000
Purchase obligation, year 2022 through 2023									$ 14,000,000
Purchase obligation, year 2024									37,000,000
Purchase obligation, year 2025 through 2031									$ 48,000,000
Duke University
License Agreements [Line Items]
Aggregate royalties payment							200,000
Sale of licensed products or services							0
Fees payment							300,000
Nonroyalty payment received							1,000,000
Research and development					0	0	0	0
Wacker
License Agreements [Line Items]
Research and development					100,000	100,000	300,000	300,000
Viamet Pharmaceuticals Holdings, LLC
License Agreements [Line Items]
Research and development					$ 0	$ 0	0	$ 100,000
License agreement upfront payment			$ 100,000
Achievement Of Clinical Development And Regulatory Milestones \| Duke University
License Agreements [Line Items]
Potential milestones payment							2,200,000
Commercial Milestones \| Duke University
License Agreements [Line Items]
Potential milestones payment							$ 400,000
Commercial Milestones \| Viamet Pharmaceuticals Holdings, LLC
License Agreements [Line Items]
Potential milestones payment			142,500,000
Achievement Of Certain Pre-Revenue Regulatory Milestones \| Alfasigma S.p.A.
License Agreements [Line Items]
Potential milestones payment		$ 35,000,000
Achievement Of Certain Commercial Milestones And Tiered Royalty Payments On Net Sales \| Alfasigma S.p.A.
License Agreements [Line Items]
Potential milestones payment		190,000,000
EMA Approval Of Application For Licensed Product \| Alfasigma S.p.A.
License Agreements [Line Items]
Potential milestones payment		10,000,000
Achievement Of Conditional Regulatory Approval From EMA \| Alfasigma S.p.A.
License Agreements [Line Items]
Potential milestones payment		12,500,000
Achievement Of Unconditional Regulatory Approval From EMA \| Alfasigma S.p.A.
License Agreements [Line Items]
Potential milestones payment		12,500,000
Achievement Of Certain Development And Intellectual Property Milestones \| Viamet Pharmaceuticals Holdings, LLC
License Agreements [Line Items]
Potential milestones payment			$ 5,100,000
MedImmune Limited
License Agreements [Line Items]
Milestone payment				$ 3,000,000
MedImmune Limited \| Achievement Of Clinical Development And Regulatory Milestones
License Agreements [Line Items]
Potential milestones payment				15,000,000
MedImmune Limited \| Commercial Milestones
License Agreements [Line Items]
Potential milestones payment				$ 50,000,000
Alfasigma S.p.A.
License Agreements [Line Items]
Upfront payment from sublicense agreement	$ 20,000,000	$ 20,000,000