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CONDENSED STATEMENTS OF STOCKHOLDERS’ EQUITY (DEFICIT) - USD ($)
$ in Thousands
Total
Common Stock
Treasury Stock
Additional Paid-in Capital
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2019   28,796,371 (29,967)    
Beginning balance at Dec. 31, 2019 $ 59,978 $ 29 $ (24) $ 222,131 $ (162,158)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock warrants 7,925     7,925  
Exercises of stock options (in shares)   14,236      
Exercise of stock options 17     17  
Stock-based compensation 471     471  
Net loss (14,905)       (14,905)
Ending balance (in shares) at Mar. 31, 2020   28,810,607 (29,967)    
Ending balance at Mar. 31, 2020 53,486 $ 29 $ (24) 230,544 (177,063)
Beginning balance (in shares) at Dec. 31, 2019   28,796,371 (29,967)    
Beginning balance at Dec. 31, 2019 59,978 $ 29 $ (24) 222,131 (162,158)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (68,190)        
Ending balance (in shares) at Sep. 30, 2020   29,389,288 (29,967)    
Ending balance at Sep. 30, 2020 4,352 $ 29 $ (24) 234,695 (230,348)
Beginning balance (in shares) at Mar. 31, 2020   28,810,607 (29,967)    
Beginning balance at Mar. 31, 2020 53,486 $ 29 $ (24) 230,544 (177,063)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in public offering, net (in shares)   80,523      
Issuance of common stock in public offering, net 473     473  
Exercises of stock options (in shares)   404      
Exercise of stock options 1     1  
Stock-based compensation 575     575  
Net loss (28,142)       (28,142)
Ending balance (in shares) at Jun. 30, 2020   28,891,534 (29,967)    
Ending balance at Jun. 30, 2020 26,393 $ 29 $ (24) 231,593 (205,205)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in public offering, net (in shares)   481,325      
Issuance of common stock in public offering, net 2,469     2,469  
Exercises of stock options (in shares)   16,429      
Exercise of stock options 24     24  
Stock-based compensation 609     609  
Net loss (25,143)       (25,143)
Ending balance (in shares) at Sep. 30, 2020   29,389,288 (29,967)    
Ending balance at Sep. 30, 2020 $ 4,352 $ 29 $ (24) 234,695 (230,348)
Beginning balance (in shares) at Dec. 31, 2020 29,441,887 29,471,854 (29,967)    
Beginning balance at Dec. 31, 2020 $ (25,202) $ 29 $ (24) 235,516 (260,723)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in public offering, net (in shares)   18,400,000      
Issuance of common stock in public offering, net 60,084 $ 19   60,065  
Exercises of stock options (in shares)   110,146      
Exercise of stock options 217     217  
Stock-based compensation 670     670  
Net loss (27,358)       (27,358)
Ending balance (in shares) at Mar. 31, 2021   47,982,000 (29,967)    
Ending balance at Mar. 31, 2021 $ 8,411 $ 48 $ (24) 296,468 (288,081)
Beginning balance (in shares) at Dec. 31, 2020 29,441,887 29,471,854 (29,967)    
Beginning balance at Dec. 31, 2020 $ (25,202) $ 29 $ (24) 235,516 (260,723)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in public offering, net (in shares)   18,400,000      
Net loss $ (87,961)        
Ending balance (in shares) at Sep. 30, 2021 48,062,483 48,092,450 (29,967)    
Ending balance at Sep. 30, 2021 $ (50,329) $ 48 $ (24) 298,331 (348,684)
Beginning balance (in shares) at Mar. 31, 2021   47,982,000 (29,967)    
Beginning balance at Mar. 31, 2021 8,411 $ 48 $ (24) 296,468 (288,081)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock in public offering, net 157     157  
Exercises of stock options (in shares)   3,615      
Exercise of stock options 6     6  
Issuance of common stock through employee share purchase plan (in shares)   72,105      
Issuance of common stock under employee stock purchase plan 202     202  
Stock-based compensation 728     728  
Net loss (28,679)       (28,679)
Ending balance (in shares) at Jun. 30, 2021   48,057,720 (29,967)    
Ending balance at Jun. 30, 2021 (19,175) $ 48 $ (24) 297,561 (316,760)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Exercises of stock options (in shares)   34,730      
Exercise of stock options 50     50  
Stock-based compensation 720     720  
Net loss $ (31,924)       (31,924)
Ending balance (in shares) at Sep. 30, 2021 48,062,483 48,092,450 (29,967)    
Ending balance at Sep. 30, 2021 $ (50,329) $ 48 $ (24) $ 298,331 $ (348,684)