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Leases
9 Months Ended
Sep. 30, 2021
Leases [Abstract]  
Leases Leases
The Company leases office and research and development facilities and equipment under various non-cancellable operating lease agreements.
In January 2010, the Company entered into a lease for office and laboratory space in Malvern, Pennsylvania (the “Malvern Lease”). The Malvern Lease commenced in March 2010 and was amended to extend its term to July 2018 and again to September 2023, with an option to extend the lease for an additional three years. This lease contains escalating rent payments. In December 2018, the Company entered into a lease for office space in San Diego, California, which expires in October 2022. In June 2020, the Company entered into a lease for additional office space in Malvern, Pennsylvania, which expires in September 2023. As of September 30, 2021, the weighted average remaining lease term for the Company’s leases was 4.0 years, and the weighted average discount rate used to determine the right-of-use assets and corresponding operating lease liabilities was 5.8%.
Maturities of operating lease liabilities as of September 30, 2021 are as follows (in thousands):

Year Ending December 31,
2021 (remaining three months)$143 
2022555 
2023419 
2024279 
2025283 
Thereafter
215 
Total future minimum lease payments
1,894 
Less: Present value adjustment
(227)
Operating lease liabilities
$1,667 
The Company recognizes rent expense for the operating leases on a straight-line basis. Rent expense was $0.2 million and $0.2 million for the three months ended September 30, 2021 and 2020, respectively, and $0.5 million and $0.4 million for the nine months ended September 30, 2021 and 2020, respectively.