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Income Taxes - Summary of Reconciliation of Income Tax Expense (Benefit) (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]    
Income tax benefit at statutory rate $ (8,242) $ (5,008)
State income tax, net of federal benefit (3,783) (1,593)
Permanent items 16 3
Fair value adjustments 0 15
Non-deductible interest expense 0 706
Stock-based compensation 56 45
Orphan drug credit (925) (475)
Research and development credits (763) (274)
Uncertain tax positions 548 222
Tax Cuts and Jobs Act 0 (15)
Change in state rate (34) 0
Change in valuation allowance 13,179 6,426
Other (52) (52)
Income tax expense (benefit) $ 0 $ 0