8-K

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549





                                    FORM 8-K
                                 Current Report


                       Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934



                Date of Report (date of earliest event reported):

                                  July 25, 2007



                     MEDICAL STAFFING NETWORK HOLDINGS, INC.
             (Exact name of registrant as specified in its charter)



          Delaware                        001-31299                65-0865171
      ----------------           -------------------------     --------------
(State or other jurisdiction      (Commission File Number)     (IRS Employer
       of incorporation)                                     Identification No.)

                901 Yamato Road, Suite 110, Boca Raton, FL 33431
                ------------------------------------------------
                    (Address of principal executive offices)

        Registrant's telephone number, including area code: 561-322-1300
                                                            ------------

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

|_| Written communications pursuant to Rule 425 under the Securities Act
    (17 CFR 230.425)

|_| Soliciting material pursuant to Rule 14a-12 under the Exchange Act
    (17 CFR 240.14a-12)

|_| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange
    Act (17 CFR 240.14d-2(b))

|_| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange
    Act (17 CFR 240.13e-4(c))



Item 7.01.  Regulation FD Disclosure

     The registrant is attaching a copy of a press release dated July 25, 2007,
as Exhibit 99.1.

Item 9.01.  Financial Statements and Exhibits

               (d)  Exhibits:

                    99.1   Press Release of Medical Staffing Network Holdings,
                           Inc., dated July 25, 2007.

Limitation on Incorporation by Reference

     In accordance with General Instruction B.2 of Form 8-K, the information in
this report (including the exhibit) is furnished pursuant to Item 7.01 and shall
not be deemed to be "filed" for the purposes of Section 18 of the Securities
Exchange Act of 1934, as amended, or otherwise subject to liabilities of that
Section, unless we specifically incorporate it by reference in a document filed
under the Securities Act of 1933 or the Securities Exchange Act of 1934. The
filing of this Current Report on Form 8-K is not an admission as to the
materiality of any information in this report that is required to be disclosed
solely by Regulation FD.


                                      -2-


                                    SIGNATURE

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.



Date:  July 25, 2007               MEDICAL STAFFING NETWORK HOLDINGS, INC.



                                   By: /s/ Kevin S. Little
                                      --------------------------------
                                       Kevin S. Little
                                       President and Chief Financial Officer

                                      -3-


                                  EXHIBIT INDEX



Exhibit No.               Description

99.1                      Press Release of Medical Staffing Network Holdings,
                          Inc., dated July 25, 2007.

                                      -4-

EX-99.1

                                                                    Exhibit 99.1

Medical Staffing Network Holdings to Discuss Second Quarter 2007 Earnings
                          on August 9, 2007

    BOCA RATON, Fla.--(BUSINESS WIRE)--July 25, 2007--Medical Staffing
Network Holdings, Inc. (NYSE: MRN), the third largest healthcare
staffing company and the largest provider of per diem nurse staffing
services in the nation as measured by revenues, today announced that
it will report its earnings for the second quarter and six months
ended July 1, 2007, after the market closes on Wednesday, August 8,
2007. The Company's management will host a conference call and webcast
to discuss the earnings release at 11:00 a.m. Eastern time, on
Thursday, August 9, 2007.

    To listen to the call, participants should dial 1-888-343-2168
approximately ten minutes prior to the start time of the call. A
telephonic replay of the call may be accessed by dialing
1-800-633-8284 and entering access code 21343155. A replay will be
available from 1:00 p.m. Eastern time on Thursday, August 9, 2007,
through 6:00 p.m. on Friday, August 10, 2007. The conference call will
also be available through the Company's website at
http://www.msnhealth.com or at www.earnings.com. A 30-day online
replay will be available approximately an hour following the
conclusion of the live broadcast.

    Company Summary

    Medical Staffing Network Holdings, Inc. is the largest provider of
per diem nurse staffing services in the United States as measured by
revenues. The Company also provides travel nurse staffing services and
is a leading provider of allied health professionals, such as
radiology and diagnostic imaging specialists, clinical laboratory
specialists, rehabilitation specialists, pharmacists and respiratory
therapists and other similar healthcare vocations.

    CONTACT: Medical Staffing Network Holdings, Inc.
             Jeff Yesner, Vice President, Finance, 561-322-1303