Exhibit 99.1

        Medical Staffing Network Holdings Announces Adamson's Intention
                      to Remain as Chief Executive Officer

    BOCA RATON, Fla.--(BUSINESS WIRE)--September 22, 2004--Medical
Staffing Network Holdings, Inc. (NYSE:MRN), a leading healthcare
staffing company and the largest provider of per diem nurse staffing
services in the nation, announced today that its Chairman and Chief
Executive Officer Robert J. Adamson will remain in his current role as
Chief Executive Officer for at least the next two years. In March of
this year, Mr. Adamson had indicated his intention to retire from his
role as Chief Executive Officer, but remain as Executive Chairman of
the Company.
    Board of Directors member David J. Wenstrup commented, "The Board
is delighted that Robert will continue as Chief Executive Officer. He
was a co-founder of the Company, and, under his leadership, Medical
Staffing Network has become one of the country's leading providers of
temporary healthcare professionals. Mr. Adamson was asked to extend
his contract as Chief Executive Officer, and he enthusiastically
agreed to recommit to the role. We are pleased that he will continue
to provide his leadership and vision to the Company."
    In commenting on the announcement, Mr. Adamson said, "I am pleased
to be extending my commitment to the role of Chief Executive Officer
and helping to steer the Company through these tumultuous industry
times. Given the recent market conditions, the Company needs to be
focused on bolstering recent positive trends and executing existing
initiatives rather than a change in senior management. I look forward
to continuing to be involved on a day-to-day basis and to seeing
first-hand the improvements resulting from all the hard work and
dedication from our management team and associates."

    Company Summary

    Medical Staffing Network Holdings, Inc. is the largest provider of
per diem nurse staffing services in the United States. The Company
also provides travel nurse staffing services and is a leading provider
of allied health professionals, including radiology specialists,
diagnostic imaging technicians and clinical laboratory technicians.

    This press release contains statements that are forward-looking in
nature. Statements that are predictive in nature, that depend upon or
refer to future events or conditions or that include words such as
"expects," "anticipates," "intends," "plans," "believes," "estimates,"
and similar expressions are forward-looking statements. These
statements involve known and unknown risks, uncertainties and other
factors that may cause the Company's actual results and performance to
be materially different from any future results or performance
expressed or implied by these forward-looking statements. These
factors include the following: Mr. Adamson's willingness to continue
his role as Chief Executive Officer for the stated two-year period,
the Company's ability to stabilize the reduction in revenue, and the
Company's ability to carry out its business strategy and the demand
for temporary nurses. Additional information concerning these and
other important factors can be found within the Company's filings with
the Securities and Exchange Commission. Statements in this press
release should be evaluated in light of these important factors.
Although the Company believes that these statements are based upon
reasonable assumptions, it cannot guarantee future results. Given
these uncertainties, the forward-looking statements discussed in this
press release might not occur.


    CONTACT: Medical Staffing Network Holdings, Inc., Boca Raton
             Robert J. Adamson, 561-322-1303