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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Operating expenses:        
Research and development $ 9,509 $ 4,966 $ 27,316 $ 12,076
General and administrative 3,148 1,486 7,402 8,410
Impairment of acquired IPR&D     21,692  
Depreciation 127 91 387 272
Total operating expenses 12,784 6,543 56,797 20,758
Loss from operations (12,784) (6,543) (56,797) (20,758)
Other income (expense):        
Interest expense, net 111 (277) (106) (1,038)
Foreign currency exchange gain (loss) (7) (71) 87 (225)
Loss on extinguishment of debt       (1,816)
Change in fair value of financial instruments 10 (43) (52) (280)
Total other income (expense) 114 (391) (71) (3,359)
Loss before income taxes (12,670) (6,934) (56,868) (24,117)
Income tax benefit 110 117 5,866 824
Net loss (12,560) (6,817) (51,002) (23,293)
Accretion of redeemable convertible preferred stock       (578)
Deemed dividend on beneficial conversion feature       (404)
Net loss attributable to common stockholders (12,560) (6,817) (51,002) (24,275)
Other comprehensive income:        
Gain (loss) on foreign currency translation (105) 348 (620) 1,343
Unrealized gain (loss) on short-term investments 13 (5) 26 (5)
Total Comprehensive Loss $ (12,652) $ (6,474) $ (51,596) $ (21,955)
Net loss per share:        
Basic and diluted $ (0.37) $ (0.28) $ (1.61) $ (1.76)
Weighted average common shares outstanding        
Basic and diluted 33,708,563 24,209,517 31,648,510 13,770,032