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Consolidated Statements of Operations and Comprehensive Income/ (Loss) (USD $)
12 Months Ended 211 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2013
Revenues:      
Net sales       $ 174,830
Licensing revenue       1,300,000
Grant revenue       618,692
Total net revenue       2,093,522
Cost of goods sold       51,094
Gross margin       2,042,428
Operating expenses:      
Research and development 12,902,263 8,088,152 98,959,719
Selling, general and administrative 8,517,781 7,519,405 76,184,493
Transaction-related expenses 79,640 (69,602) 751,292
Depreciation and amortization 39,517 90,047 11,064,752
Write-off of in-process research and development       10,422,130
Goodwill impairment       5,702,130
Equity in loss of investee       178,936
Total operating expenses 21,539,201 15,628,002 203,263,452
Loss from operations (21,539,201) (15,628,002) (201,221,024)
Reduction of fair value of warrants       (12,239,688)
Interest income 60,268 73,560 4,892,476
Interest expense       (191,729)
Other income (expense), net (1,352) (5,047) 128,353
Loss before cumulative effect of change in accounting principle (21,480,285) (15,559,489) (208,631,612)
Cumulative effect of change in accounting principle       (25,821)
Net loss (21,480,285) (15,559,489) (208,657,433)
Preferred stock dividends       (621,240)
Deemed dividends on preferred stock       (10,506,683)
Net loss applicable to common stock (21,480,285) (15,559,489) (219,785,356)
Loss per common share - basic and diluted $ (0.28) $ (0.33)  
Weighted average shares outstanding - basic and diluted 76,585,752 47,641,043  
Comprehensive Income/(Loss):      
Net loss (21,480,285) (15,559,489) (208,657,433)
Unrealized gains (losses) on marketable securities (18,544) 104 (18,582)
Foreign currency translation adjustments       (2,156)
Comprehensive net loss $ (21,498,829) $ (15,559,385) $ (208,678,171)