Income Taxes - Components of Deferred Tax Assets (Liabilities) (Details) - USD ($) $ in Thousands	Dec. 31, 2023	Dec. 31, 2022
Deferred tax assets
Net operating loss carryforwards	$ 32,753	$ 32,887
Deferred revenue	31	837
Research and development and orphan drug credits	38,192	96,133
Share-based compensation	5,024	6,353
ASC 842 lease liability	7,258	2,480
Capitalized research expense	19,543	10,168
Transaction related expense	0	2,354
Inventory related reserves	13,561	18,395
Other, net	6,715	3,054
Total deferred tax assets	123,077	172,661
Valuation allowance for deferred tax assets	(2,588)	(707)
Deferred tax assets, net of valuation allowance	120,489	171,954
Deferred tax liabilities
Non-deductible book amortization	(103,492)	(115,578)
Depreciation	(3,522)	(2,559)
ASC 842 right of use asset	(8,259)	(9,061)
Other, net	(830)	(330)
Total deferred tax liabilities	(116,103)	(127,528)
Net deferred tax asset	$ 4,386	$ 44,426