Condensed Consolidated Statements of Operations (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenues:
Total revenues	$ 152,365	$ 136,455	$ 269,644	$ 225,477
Operating expenses:
Cost of sales	33,943	23,018	49,865	41,237
Amortization of intangibles	11,403	0	11,403	0
Research and development	15,483	8,069	27,336	17,078
Selling, general and administrative	57,476	12,321	71,310	23,380
Total operating expenses	118,305	43,408	159,914	81,695
Operating income	34,060	93,047	109,730	143,782
Other income (expense):
Investment and other (expense) income, net	(945)	221	(447)	497
Inducement expense related to convertible notes	0	0	0	(20,960)
Interest expense	(3,104)	(1,752)	(4,863)	(3,717)
Net income before income taxes	30,011	91,516	104,420	119,602
Income tax expense	7,326	58	21,627	249
Net income	$ 22,685	$ 91,458	$ 82,793	$ 119,353
Net income per share:
Basic (USD per share)	$ 0.16	$ 0.64	$ 0.60	$ 0.85
Diluted (USD per share)	$ 0.16	$ 0.62	$ 0.58	$ 0.81
Shares used in computing net income per share:
Basic (shares)	137,937	142,487	137,798	140,201
Diluted (shares)	142,216	147,624	141,795	148,096
Royalties
Revenues:
Total revenues	$ 85,340	$ 45,778	$ 154,945	$ 82,701
Product sales, net
Revenues:
Total revenues	46,300	30,360	68,440	52,126
Revenues under collaborative agreements
Revenues:
Total revenues	$ 20,725	$ 60,317	$ 46,259	$ 90,650