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Certain Balance Sheet Items (Tables)
9 Months Ended
Sep. 30, 2020
Balance Sheet Related Disclosures [Abstract]  
Schedule of accounts receivable
Accounts receivable, net consisted of the following (in thousands):
 
 
September 30,
2020
 
December 31,
2019
Accounts receivable from product sales to collaborators
 
$
3,198

 
$
35,649

Accounts receivable from revenues under collaborative agreements
 
476

 
3,850

Accounts receivable from royalty payments
 
24,067

 
17,149

Accounts receivable from other product sales
 
4,052

 
3,591

Other contract assets
 
32,000

 

     Subtotal
 
63,793

 
60,239

Allowance for distribution fees and discounts
 
(1,242
)
 
(797
)
     Total accounts receivable, net
 
$
62,551

 
$
59,442


Schedule of inventories
Inventories consisted of the following (in thousands):
 
 
September 30,
2020
 
December 31,
2019
Raw materials
 
$
5,473

 
$
2,769

Work-in-process
 
20,953

 
15,710

Finished goods
 
31,271

 
10,880

     Total inventories
 
$
57,697

 
$
29,359


Schedule of prepaid expenses and other assets
Prepaid expenses and other assets consisted of the following (in thousands):
 
 
September 30,
2020
 
December 31,
2019
Prepaid manufacturing expenses
 
$
37,606

 
$
30,156

Prepaid research and development expenses
 
550

 
4,964

Other prepaid expenses
 
3,223

 
3,655

Other assets
 
4,944

 
5,681

     Total prepaid expenses and other assets
 
46,323

 
44,456

Less long-term portion
 
14,382

 
11,083

     Total prepaid expenses and other assets, current
 
$
31,941

 
$
33,373


Schedule of property and equipment, net
Property and equipment, net consisted of the following (in thousands):
 
 
September 30,
2020
 
December 31,
2019
Research equipment
 
$
7,465

 
$
7,403

Manufacturing equipment
 
4,414

 
3,858

Computer and office equipment
 
4,856

 
4,859

Leasehold improvements
 
1,628

 
1,628

     Subtotal
 
18,363

 
17,748

Accumulated depreciation and amortization
 
(11,786
)
 
(10,742
)
     Subtotal
 
6,577

 
7,006

Right of use assets
 
3,675

 
3,849

     Property and equipment, net
 
$
10,252

 
$
10,855

Schedule of accrued expenses
Accrued expenses consisted of the following (in thousands):
 
 
September 30,
2020
 
December 31,
2019
Accrued outsourced research and development expenses
 
$
918

 
$
8,423

Accrued compensation and payroll taxes
 
7,372

 
27,888

Accrued outsourced manufacturing expenses
 
6,946

 
9,173

Other accrued expenses
 
8,765

 
7,876

Lease liability
 
5,523

 
6,469

     Total accrued expenses
 
29,524

 
59,829

Less long-term portion
 
3,729

 
4,180

     Total accrued expenses, current
 
$
25,795

 
$
55,649


Schedule of deferred revenue
Deferred revenue consisted of the following (in thousands):
 
 
September 30,
2020
 
December 31,
2019
Collaborative agreements
 
 
 
 
License fees and event-based payments
 
$

 
$
2,764

Product sales
 
1,389

 
2,495

Total deferred revenue
 
1,389

 
5,259

Less current portion
 
748

 
4,012

Deferred revenue, net of current portion
 
$
641

 
$
1,247