Certain Balance Sheet Items (Tables)
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12 Months Ended |
Dec. 31, 2019 |
Balance Sheet Related Disclosures [Abstract] |
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Summary of Accounts Receivable |
Accounts receivable, net consisted of the following (in thousands): | | | | | | | | | | | | December 31, 2019 | | December 31, 2018 | Accounts receivable from product sales to collaborators | | $ | 35,649 |
| | $ | 3,717 |
| Accounts receivable from revenues under collaborative agreements | | 3,850 |
| | 5,499 |
| Accounts receivable from royalty payments | | 17,149 |
| | 19,199 |
| Accounts receivable from other product sales | | 3,591 |
| | 2,182 |
| Subtotal | | 60,239 |
| | 30,597 |
| Allowance for distribution fees and discounts | | (797 | ) | | (592 | ) | Total accounts receivable, net | | $ | 59,442 |
| | $ | 30,005 |
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Summary of Inventories |
Inventories consisted of the following (in thousands): | | | | | | | | | | | | December 31, 2019 | | December 31, 2018 | Raw materials | | $ | 2,769 |
| | $ | 735 |
| Work-in-process | | 15,710 |
| | 11,430 |
| Finished goods | | 10,880 |
| | 10,460 |
| Total inventories | | $ | 29,359 |
| | $ | 22,625 |
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Summary of Prepaid Expenses and Other Assets |
Prepaid expenses and other assets consisted of the following (in thousands): | | | | | | | | | | | | December 31, 2019 | | December 31, 2018 | Prepaid manufacturing expenses | | $ | 30,156 |
| | $ | 8,230 |
| Prepaid research and development expenses | | 4,964 |
| | 7,922 |
| Other prepaid expenses | | 3,655 |
| | 2,513 |
| Other assets | | 5,681 |
| | 6,462 |
| Total prepaid expenses and other assets | | 44,456 |
| | 25,127 |
| Less long-term portion | | 11,083 |
| | 4,434 |
| Total prepaid expenses and other assets, current | | $ | 33,373 |
| | $ | 20,693 |
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Summary of Property and Equipment |
Property and equipment, net consisted of the following (in thousands): | | | | | | | | | | | | December 31, 2019 | | December 31, 2018 | Research equipment | | $ | 7,403 |
| | $ | 9,945 |
| Manufacturing equipment | | 3,858 |
| | 3,979 |
| Computer and office equipment | | 4,859 |
| | 5,211 |
| Leasehold improvements | | 1,628 |
| | 4,569 |
| Subtotal | | 17,748 |
| | 23,704 |
| Accumulated depreciation and amortization | | (10,742 | ) | | (16,239 | ) | Subtotal | | $ | 7,006 |
| | $ | 7,465 |
| Right of use of assets | | $ | 3,849 |
| | $ | — |
| Property and equipment, net | | $ | 10,855 |
| | $ | 7,465 |
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Summary of Accrued Expenses |
Accrued expenses consisted of the following (in thousands): | | | | | | | | | | | | December 31, 2019 | | December 31, 2018 | Accrued outsourced research and development expenses | | $ | 8,423 |
| | $ | 21,921 |
| Accrued compensation and payroll taxes | | 27,888 |
| | 16,604 |
| Accrued outsourced manufacturing expenses | | 9,173 |
| | 3,975 |
| Other accrued expenses | | 7,876 |
| | 7,623 |
| Lease liability | | 6,469 |
| | — |
| Total accrued expenses | | 59,829 |
| | 50,123 |
| Less long-term portion | | 4,180 |
| | 594 |
| Total accrued expenses, current | | $ | 55,649 |
| | $ | 49,529 |
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Summary of Deferred Revenue |
Deferred revenue consisted of the following (in thousands): | | | | | | | | | | | | December 31, 2019 | | December 31, 2018 | Collaborative agreements | | | | | License fees and event-based payments: | | 2,764 |
| | 2,264 |
| Product sales | | 2,495 |
| | 6,991 |
| Total deferred revenue | | 5,259 |
| | 9,255 |
| Less current portion | | 4,012 |
| | 4,247 |
| Deferred revenue, net of current portion | | $ | 1,247 |
| | $ | 5,008 |
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