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Certain Balance Sheet Items (Tables)
12 Months Ended
Dec. 31, 2019
Balance Sheet Related Disclosures [Abstract]  
Summary of Accounts Receivable
Accounts receivable, net consisted of the following (in thousands):
 
 
December 31,
2019
 
December 31,
2018
Accounts receivable from product sales to collaborators
 
$
35,649

 
$
3,717

Accounts receivable from revenues under collaborative agreements
 
3,850

 
5,499

Accounts receivable from royalty payments
 
17,149

 
19,199

Accounts receivable from other product sales
 
3,591

 
2,182

     Subtotal
 
60,239

 
30,597

Allowance for distribution fees and discounts
 
(797
)
 
(592
)
     Total accounts receivable, net
 
$
59,442

 
$
30,005


Summary of Inventories
Inventories consisted of the following (in thousands):
 
 
December 31,
2019
 
December 31,
2018
Raw materials
 
$
2,769

 
$
735

Work-in-process
 
15,710

 
11,430

Finished goods
 
10,880

 
10,460

     Total inventories
 
$
29,359

 
$
22,625


Summary of Prepaid Expenses and Other Assets
Prepaid expenses and other assets consisted of the following (in thousands):
 
 
December 31,
2019
 
December 31,
2018
Prepaid manufacturing expenses
 
$
30,156

 
$
8,230

Prepaid research and development expenses
 
4,964

 
7,922

Other prepaid expenses
 
3,655

 
2,513

Other assets
 
5,681

 
6,462

     Total prepaid expenses and other assets
 
44,456

 
25,127

Less long-term portion
 
11,083

 
4,434

     Total prepaid expenses and other assets, current
 
$
33,373

 
$
20,693


Summary of Property and Equipment
Property and equipment, net consisted of the following (in thousands):
 
 
December 31,
2019
 
December 31,
2018
Research equipment
 
$
7,403

 
$
9,945

Manufacturing equipment
 
3,858

 
3,979

Computer and office equipment
 
4,859

 
5,211

Leasehold improvements
 
1,628

 
4,569

     Subtotal
 
17,748

 
23,704

Accumulated depreciation and amortization
 
(10,742
)
 
(16,239
)
Subtotal
 
$
7,006

 
$
7,465

Right of use of assets
 
$
3,849

 
$

     Property and equipment, net
 
$
10,855

 
$
7,465

Summary of Accrued Expenses
Accrued expenses consisted of the following (in thousands):
 
 
December 31,
2019
 
December 31,
2018
Accrued outsourced research and development expenses
 
$
8,423

 
$
21,921

Accrued compensation and payroll taxes
 
27,888

 
16,604

Accrued outsourced manufacturing expenses
 
9,173

 
3,975

Other accrued expenses
 
7,876

 
7,623

Lease liability
 
6,469

 

     Total accrued expenses
 
59,829

 
50,123

Less long-term portion
 
4,180

 
594

     Total accrued expenses, current
 
$
55,649

 
$
49,529


Summary of Deferred Revenue
Deferred revenue consisted of the following (in thousands):
 
 
December 31,
2019
 
December 31,
2018
Collaborative agreements
 
 
 
 
License fees and event-based payments:
 
2,764

 
2,264

Product sales
 
2,495

 
6,991

Total deferred revenue
 
5,259

 
9,255

Less current portion
 
4,012

 
4,247

Deferred revenue, net of current portion
 
$
1,247

 
$
5,008