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Summary of Significant Accounting Policies Inventories (Details) - USD ($)
$ in Thousands
Dec. 31, 2017
Dec. 31, 2016
Inventory [Line Items]    
Inventory, Net $ 5,146 $ 14,623
Hylenex Recombinant [Member]    
Inventory [Line Items]    
Inventory, Net 2,900 2,300
bulk rHuPH20    
Inventory [Line Items]    
Inventory, Net $ 2,200 $ 12,300