cc: | Jean Liu, Halozyme Therapeutics, Inc. |
$/^$`-DN`'7@!.X40"K&401S@01@(PB'(1[:!"$;AU"8$/ M=;!\]4.'Y6`%71,CO(@0Y4!3#[6.S@4^V^,'$L$MO<$`VA(1G^)`!RP0E@*Q?[UQ!')`!#!3 M!;QI5B#I1W4)$9K$21*QE_XTD/_@#WD`>DE"`G%)$;1`!E3^]113A#X]<)86 M`92M!@O(9A[?0`NZ4%_ 0A?.(V_H`L2>J(HFJ+=)8T-<0P=AW<&>ENYD`OU:9^TD)$',9^\ MH**Q8(P*T0T1FJ+XJ70,T0_=D`N$(`9$<`$=*J!$1U%1@`>:T`R]]18DB95' MX*,;HVI"D1< *",I0`:(R8%[8#T<(#T6$69!00GQN"IR<`#8\Y'0=1#3 M55UR90!S>D1]U5[B0`8,8`?1UB_^/0`&'Y`&!O587#`0^_`(),``MXE90:`$ MVVD0H26!!5%:-R@0^#`%$M!%!*%@L340\T`'"I`#J*!5Q[AUVT`#UND0Z[`, MCW`&2N!_0L=S4J($9.`(T^"37TH0VV`QNB$!;#)QSG820\DHS&6<"'"=!+$/ MU,6B_^`'!J!^SH4%-)`-:?D"T#D0>H``A$`-TS"NT9`@!X!/$)"6`%VT`. M[6!0VS"I\2D0ERJ9D&``P$OMD^!`&'(`&DBD1(^(QF>`*Y3FQ(+MCD\`!HXH1XOFP:1:R M*LMC\5#^I1A!#,=Q"6^ZLC2+:,R6$LE:LSK+9C!+"1&[LT#;9J^T"A\;M$;K M90F$>[M$S;M$YK9?UP#^H0#E0[#KWVM%C[8N'P"B;Q%YOP&,YP@ED[MFTR M#D51;4+E#&2[M@^B#QV#MBR1">3)MG3['.QP8W`;MWU8MWP+&T*6MRVQ":I0 MM!0A#]=0#+7PM9?0;`,8%&5A%D!1"\10#>S@C7U[N?\P#HT'N,D!#12A#L3P M&)Q+%LW6;)=PNG<&MCF+N6/+#IL[NI>PMPLA#\RPN)QK%JM@#-Y`N*S;NPE1 M#ZFPF*HQ9ZL[$/<@#"Q7:\W&/BN\Z;$>.P"@Y+@@;GJP/^H0ZP,+T)XJ:A M\KS>&Q+^\`[A``VWH`JI<+ZJ``O&H`WJP+L$D0S)*VB7L`O-^[WVNQC#H+VJ M<0FUT+WWV[?[``[(,`EU,`5$$!\Y=P%I]Z&"&`15,`C!4*DUP:;*JPK%^[]- MFPV&``;H1#L.)R4'"Q(LQ6J9P`KUB\%-:PUVP`&4!W?7D3[ZJ1$C+&B9H`K^ MB\)&FP^-$#0N['`.L*<:,6^"-F?C@,-+BPEEU\,]G`-5(,$440^NT+A5,51& M;+2T\`+`UW^($S<>['`Y8)8940WQ2X(I6\4K&P]HP'_6P3AIH`M.C!"H@(X. MQP)N4(L*X0]<.KPFO!?!9L:89P[^?84=MZ2,$[$.7-!O[F$A>0D1)ZL2)K() M*+(E;$`%*>``>?-V+@P?A3,(,>S';.8/*:F`]N,1U!`$65P=$F"M$A&Z6[(& MI_(![*;$:9("5K"5GJQF\1`LU<$!AS`2%7/*OY'*#K$/VMH%*2`?,H)!&N0$ M7[`&;/#,7&()EM!LMU">_;`/^5`.R(`)A:`'8\`"L/QPN=')MPQE"OL;%R`( MUML1A:#&V2$!)_FLQ[`'1Q"@A5@%@-`*T6`."Z4-F6`*7BL*-QP1\<`'=Y<= M)'`'EEO.1>:6'OP!B_P1640C-#`%&8(.O#!\#M$/;_L7IS!F&E$.5S ^`&L;GN1TA"=*$'?MSTE5&"&J<`OE: M$_D@!G=8(3F@I1*A:"1X"PM-$;,%T[UQ`9C@TU=VSDX3!.3L$6?:(2%EQP@Q MPV+ALQ[A#WRP?+]!`FZ`B59=94+T&Q82PA*Q#]9`"%90`&2`#`O31EX-JC0- M2W>1"8W6$>:P4]CA`(0`UJ1%,E/2V(@C`8:@V`CA#X[`-([=V#1P`820?S/1 M#G>@08T=(!O8U@DA4&('SDH@!XX0"[\0#,&0"ZA0"&@`!4%`?R3@`%$0"%O] M#QXH(#1@!2XK$9@3V+*+$?O`!]3Y'A*0!AJ-$0L9/CD`! JA'! MP`1'O4E=(*T `/)-D=49H'KA3^H`?.B(?%2GP0GA(=Z[X)00U\U#5Z M $T8X_:L:D(00L<@,6T,UR,(P%84`CBMQ`BOA#=4`AB4"4I`"/A ME`,O4$Q0P`<"JQ"#4``,NN5 _N5<[@`](`?14!'=8`=:[N4'(`=*8`!; MKG,`FIS34` 3!8>$@'1MD6#2/59&,' M&)&_8ZW^M`71#L?`!SW@`!P@YF=`", 7($-:`R1*@C%N?`G4,$24^2'\WX031#_Z"I3ZZ!X/T M`F>`#,N`#+S?^[[_^[W?#.&(/E$0W&SAF]5QF9P=$4P]%)G^T`O0@>/U*."( M3Q#QH`N%4`>DPO(D<.'O47;"R9>.W^M4>4+[T'J]X0"MA!&5[N@WF1#-@"\` MDP/IY1"_K$Y5X/5BF`8O(]0&M?4`P8'0/X(%#1XLV"Q'CR`-@UR@A5#B04@. M'`;I0>(7P402+CI,(4'D2)(E39Z48"#B1)8M7;YL:8O#QX\? R2*)X] M??+,!.L>3J)%C1Y%N.]-BH\TM-A#RE(ITXLIWNP[B.H"#9HO2$`1I(O:.8F? M&%S,N''BM!XY+CJ`1'!=%:X72>R)>G#;$;<.>[Q`-C';D;I^.:P\^HL$0Y!7 M)4+RV)!A-I;VM!0.(O`HV[X-(1[^-8M6(T%"%VA*2)17]6K6_[(1Z?PQAY)R MJ^^YRO13MZA,X5K_!MYR:M.GP8=7=4PP&(F/&741#>V71#"6G-_&5;[X(P=! MK/E\^"@!N\%V9*A>_*`'ZVI=,R]RV+/^7SPQ+QQ**.32,F;-1JT[_,RHZ"0; MC:`\P/LH!3GD"Z[!X.;A`K.++CB$-74VV60WGRB1QD$/'=P#09`6-&ZI!)/[ M!Q6++J(!"G&@.^LB"1JIKJWK#)HG#>:VXX-!G/8YQ#V'2#@#'H/.$6/']^KP MT:@F'1&R(0XP^:>0R()(`8TF$=KOO8'\LQ%`Q&`432V"SNF"!9K^NNE#-Z-J MY$JT6'C^AK5P=M*0ITN<>;//U=JAJZDIS`D.'BPDI&%0@WXQK;GT*)NH'W3^ M:>8%QAQ:"!*H#FJ&AM@ 8<>^(1!QE)!#!`Y(J&)6A/*10\E2<^@&)WPN M\_*H:,+T;$R<,(F10#,-Z@8,$=&Z0`M!FMG2H'[*F80.%A(X8QX_5SLFA4M! M0B,?UIBA)$_>=M%G7X6-XH6#'AZ&&.(+6ODM&( <> M:$`@OH7S(H<)6%^.A;5[9LE-PTU.>>=MO_\&/'#!%P8GB,ZRW'1PQ1?WLQ\Y MSFLH!3=476V \<\\77D<+^QJB(8K:/D<]=:("63<(!QQI#9J" M-:2D&M5OQSUWQI&Q8A&N#0HFA]$;AA@$HGRJ:*`8P[*HX#NO1_@`&G'3\```PHH@(0R M;&%I&Q(,>('/)#*)`3``?P1@`!?^!C&I@F1#`@GP7O8&$`B#',,`.=`70A8Q M`#*L1P[8RQX#'%``"0Z`.O_(10$X\**#[`,39.```4A8``3PP2#[:(05[*>` M`PP@9@<1!Q\X,+RT8>0#+VA$XJJW1,^98PJ%X0`%6:,/6%S.)YGH!1,7IA0$ MI(9+6D#`)\Y'A@\$QB!^,(`7)V(/++Q@&@:Q!;Z:-(@"+`(?8E#`(,J"@.(4 MY!,&L(,_"+*-("B!'"U!!@FPH,2"0.(`*"K(.J9P@7,5Y!<<8,(A"9(/-$B` M#!EDB2XDH`4C:=&4I\2)/^QPGNFT1AT:RH0JY(%*/W%1C0:Q3`K(D`<[]+*7 M=Z@#$UC^8,:"^.$"8+B#+^4`NX)8QE0,2,$>(,'"@[2C"Q^@1D%RD<"D&>03 M"B""'?;@A0L8``S1,,@VB-`#.22SEW3(9D$2N +V4887T,`+I5R-/$Z1 M(9] 4R@8W] M%MC`!^;N(\#QFW>0EZO40W"$)3QA`X ZSP?3 9$L/P,J0UO6G5L&,36ZUTGS_M&TZ7VM0P MN5.H5;VA#IW:U:\FB.56/6NN7@/6M^8T%4%-:U&+&->_=K2L>3UK2O!)Y38E,G`(6O6#& M-=0Q[67^MQNYUW#VLT6MBA';!AO#4(6WW2QOGWQZQZ?8!334D6QW%QR5.N9W MJ#,A#((711N[R`2Y$[YJ?[LB&8(V>,9U]X[A3KS/+#8*.Y*1"?IZO-\D)W >=X3/5,"%L;`QCL: M#A-]+#WG3Q^=\)+-1R?YK>>C5%O MB:@#%G]_]B580>K"5SZY[!"&Q"EN=,I/A!V/KWHFI#%WRY?^_JOW\,8N>$-N M#+4>Y9FH1=)?HH]=0)[7E[C%S4V_>^WVXQ[R>(<\[D%ZEES#]K0>,N-YO_P( MOP/O)J?$+1K-?.I'&-XFO\0L^E9][N]+4ME`ABU0X8A"^*$/?SB$)&AQC&R0 M=G#ZZ,7Q59V)5PR^^_=7S3ZL@8HW'.$%$B`!J;D9M,@!G2&!+D`%]UL8>7B^ MA!LU_(/`U4`'27`#%B`!6"FB#/P`+0"L?7F'5*"TR.L%Y8O`$G2);@B$(W`` M(LK`%NP*%N"%/KF0$.2U3[,_$\1!E6D%,-@*%_3!%I2`'W*0&4RX2\"T'$1" M\D@$*#B9'W3"#)2`+VF0!J/!67O^N\Y+0AP,!B9HG2?T0I!9&W0*CGI@A;R; M/^O*PAP\!SZ0``S\PC>LB3\(#G_0*G[CL30TP6:``FN!PSZD"1H0@]]A#6/@ M.E6S03R,0']H!`Z0$#]T1$QQD=^XOF?+!%8(.T3DOHH8P$?DQ!S(`3$,+A"D MQ%O`.DPTO5\0'B_\BPL`#RBH@BJ8@B-(@1[D1,.!@M-9#8B+/&$PQ>[K!BS@ MPR+J@13X`"Z`!&H`)8D0A^=R0R]\@4!D#2'3.PCK1>K[`SDI(A;P)%Y(1IPX MA%N!0ZUA#6%;-5,P1]$CB'VP!W`XAO%+A$((A#[0`SR@QSWH@T`0K4]`AG.( MKVHL-7_^VL2F"$+GR8M6B)(O?)W5T`>\,1AS-(5-,(5(4`0V8(,O<`(6<`!6 M3($70)L?7!L6^``)T"5!("9_Y+1]``1PQ!D."(.>:HWO@,,<.`*V4@V"\0F' M-`5*4(2);((>@"Y+J<6T>9D>:(1X,$E( RK#*+" W_$(2P`.C:(=C2,&SN9F/ M=!8)\)@@:`(J^((O6`,VT`,_\$S/U(,Z2`,QB((78(`+(`'^H'S$#YB#4@1, M*CNPC(#R"1-UD&3U'%%&`JX6B&-#`5H&R+%X`N&B`")Z!(18@$-[M*G#Q' M;R"*?%B&/<@,N/1!!@B5UP0S:V"!3>R!#^`?/WF$%7G"#[`AP2B$,&!%X6Q# M*,`#5$`&;K"$A\3)2KN$5D.*;*"#@W3"N\#.+\L&PP&9TL'%/LF#8&S!1"'( M?U@'24"#4@$5`U5RUL?#,4QK9E]TBT[2Q"=6H M!U$T1*%P$%VHU:X@@FRY,7`@2VB=B'FH#Y`A@4%XUI D57-`LI$"&DRU3,&!>H[B-N=V-2IP^UFB%U,29'+B` M.\@I!^F'.N!#[2T1$[4*\/T0\:7:\MV7@<'PR0O$B&GM6-#)DSUM"$G0'# M"U""N?20[B6=/OH-%,822/H;"29?"@: `@@_X8P;X M`"4P@T`(AB5NH64PA#KH`C]696B*`C3X@UC(WU."!VZ)R\)=#6D,M4NPM:/` MAT8@`G`<1@YX@V!89H49XR.."C-V867$`C5Q01IP`#`HR1KYE!@VB'(@!":` MXWLUG&?^T8//0@AR>").9`$B,I4C`-2CB( _H(%NH(9UVHXOT013:='_ MDX.-)0A;F(+O (&N5(*CCH*MI$5>)0%F.@AR"!3)\$1/M.<@:!%P:`:T ME(P/2-NB6(Y_(0&F"@83Y8!$>(;>0NNM4((IJ`(EX,I-3`$F@)1)N,"&X,K9 M\&NY:=P\!>N)6`8L8%*?3`$B<,4I4`*\7!,)F`.=72)';4'^!=%7A%A3A=N% M2I:(<[`%,F``KL@!$I``+N"#(58<%NX!)>"#S]3MW>;MWOY,/K`"6#ECEO@# M`SB#0]#G@U@&-U#)A7AJB;CC@YB'/0C6"X""1*AC@D#!QRT5[S0(>/`"!:`! M-R`$2!`+<``':@B&5I"$13"$0."#/.`"#/R`[R4(<(`"S.C.MRT*0Y"3"Z#6 M?^B2BRC`'&"!/4AN@C@&,F)70S@#%B`"KB@$SRZ(;S@0%S6$B2@',.##U[:# M=C8(?Z`%.6A"`!$$7V:<3FU;F237O)C$1,N$68#>!EH$)DP!KDR!,R@$:D#Q MMV'AO4R;X=XL>"D*%#95K(ON@HC^A=/U"PJ!8'`@@V"L[X!:AT!XHZ(`!/W4 M&(.@!G`Q'"*@:)B(!I36FH<:\/>HTY !&SL`1:` M 0!"Z0@`-@`"BH@T7@\>KY M<8PHFDP?&I`1\M:(4[0`7*AVB`E6F4%0218P@]=]"5U@`5@Q\#`VBFV``A9\ M@2IX[H(X!NUP"!JP@NR>"'/(;Y!(45QR9@"YX9?8!P5>$PZH&Z*X<+O(@X,@ M!&Q\@3!0]98(]*9@`E__'`M.WO %*<@$E,Z0$QC%VEC/`7P/N\U_N]UWNLEPTB2'#4:06A?0^V M-(I,A7%_M:BB!PYR!M]]:(=E@(1!B*T><(`/:$3I(*J"B.[^THC#U@B$@\P! MP'\)LT_X-.A&EICV\!#"B>A
P"#S#?VU?"'88!5/ 18DV T)/ M$C5:,<4;F0#0PV6/'!P^](C^LJ=5M'8%/RUL^#!BR6E9*SJ`1'!=%1HN M)31:BC`;D99F(9JD)>%J11I'OBV]0['B!50ES6&1RU`"(9/VM#AFR"%R4+5Z M&0H42K;B68)]#E>4$,LNZM2J$2Z2X+)BCB/B5-=+M4DG;E&4G*WN[3METZ-) M?_\+_C2J06LL*C?\T(56.92?]Z(EJ9FMVW_S*+M\T27>:FI!-H\/,A)A/# KUA9T%-9Q%?_V#BP&LLH/$><0TZN,X4 MY+GT@2ZK24-);CI=,HR#'?X6'T-(*?7A?<>]!TY>+K$@ACD^#>A0@=:MU5!; M!37BFDO^*1RS&BT7J&A&/@A1P])K#K2B6CMGL``;%.`<5(B/#+T0AEB2<==0 M?YG-R-E``I9%(%KQ=,$<0P[4Y2&:JQV3`F"O?0#(:NK SB3YIY+@5B M$"(2QR=4[Z&"(&Q,S.;BEY;98M)_96;W#XH2QD9.:N4P05X/+$1S4#Z$1/E4 M%8A4IR.!J@")' M4#!LOO0KHA/"F1:ZZA:T3,KZ\AO4(A>TV><4VQC43Q^?5ELT:OO8LN-!D59D M+3AGT!N$!(^^RI^L/]':<,W4'10+"4-+F8/!J5DCJLDIY4*:2Q=4K-H[I\R9 MX2:GO-,VW_N0L61@6(#W(1J`-T0#%O,4E(\;VLIG",LE#>KFST+FC`E"Y%AA M^.%!+((M4X_D0.8%>2A>4#E><"[E&>CDLP^>/N$3S!]5'*#UO65WU^8%C_B$ M,)9=^_1UET"A\G",!8DC1L^!T1#^"-LS[;/,'@J K1B#IV;,) 2J;^! .%J M# W;"%(1K7O,>\(3H& MP42[B'61%Z2`!!_@P`4DP``.T$`)4]`"%J#P`@=P@`57N0#F3'(,H1$K"!SH M0S]\0@XHD.<#?!#*,7S(EB`"Y48N<<`G2M*-,A#Q-32X``W<0`A--$,<\;!' M.\"QC$\4H@Y3D``)$$@?\Z$$+QO+BOSL,HYET2D3XZ!CR?J1AQ$R)`5N`)UJ M_,$'0@;^(05I0.0_J!$%N&%E=#1`H!G641!P6(&1,,H%0?KAAM71H`OG,$D[ M"D$"W;WF(C2XI-G&PX$C?()E\3`#)8NHRUUR0#$H,0<9",D",YQN)GZH(&A2 M,,??F6%U5R',3\[!!3*]X`R0-,@^:"&&"[P@EF:Q)"RQ0H)F`!(EDV//D51S M#U7<+3>7"$ %[@G0#D@@4"TR"#SR,497DB# M6.:`!,4S2#?RD`()L$`O+/!"B]81B`1\`*"K_(`#`J%)D^#C&'>H"@V]V8,7 M2"`%4UB$T1#BCTDXH*,>O2E.<_J!#U0G)?AJ$PV88,*AH(+^I3A5`!IB>I)X M'**F.$U`'H9JDG/P(0$X_8`$_+"-)$XU%W4(P@>XN;%ODD`"+]!"(D8:3Y+8 M0PP&+.0A5U.-D&7H$CU9*UX!:8Y<0&(CAUC$)()13)/,PQJM`&R:T!$,3"SB M$(DX1",^\8Q]YO4@_N@#,F'DL ,$.V.LG$+:!EW?&2M[PD2832)$!%\[+708L( M+D-@TIMQM/.[K[A'>_.KWWB>LB3^RR!"97J0@F7LM\"JZ4<='!>;;O1&&,?- MR28VP0X#4[C">9K'(5A(`CFT`AWV,$ &&+1F#!` $$0!?''(A!``D+H`AG!@,0R"]*/6`2!!11ER8HMLN(<&)P%>9C&IR..D'TH MZ7!4Z@WX,N1'B4\+`7,["*I5S:E6O]H@?C#`Q]F*A1=`O""H2``9KHD,#I`! M$RP@`=0.\@D$#(<@_MA#`BQ-D&T$00GK)@FVM4V2;K\,S%.X0$\+@FYU&\06 M#/B`N4X2#`F(H 3^'6_U^."=8*/M M3'F#Q]FJ!03X$B$DA[4!B%T2>ZR<&@89A`'T,'$S2("N0@!'623'W=*,J:3W>:"*_;O?5"(41F+Q"(WO@#%W/7 M#31<7Q*BY!TA^V$X"X(O_(J^H.0%\0-76,*2"_3!()-Y01T*P0 />#2##`D0PZ/_L8TCL%;Y-$B!\:^=;<\7!/0($7W4 M"5+Z@O#B`E;X\DF40QY\0`)P`!9`@E3IG@*B!#ZX%4.PP!FP'E!<2&Y00C(L MX,3A7 $_A)P:CN#Q M!9Y^K%S+60,-*("]&40=&``.%H0@(``=@!_/T=]!9%[ZD40\:`$#/-%!#$D* MG,=!X%_^)%+=NEP`"T2!D$E@-/3`!1#8)FIA.TQ3(\G!#,*6*.9$)L`"?FWC M/I3!`!0"2
V#'Q0` M&_Y#(0P`&ES3/Y@#$1#`("3$`!#!8-W%!S```NSC`0Q`1!I$/AC"!Q0`"51! M%1"!`3@`((0+2:`##10`*"%$+AA`"D2//4@"%"B``2A`'A8``9"!5'S#`1A` M#B@!"Q0``^C!,&ZC`A[(>!P!@ZT&.XR/3LR8/"BE5>Z#/=B#!'[(/GB=/^2# M5EJE)J),IH!A:OC#,#P8IU6E6+:E6[ZEM&"7L#F";]0$;DC^&%SFI5[NI6\\ M@@-,B4JJ$RL\V"7\$5\>)F(FIDD@F!\RHVK,E89X@V).)F4BYL`X0"ZBAIRT MTR5<0V5^)FBZI>75P5;Z1#_LPG%=0NZ%)FNVIA:*4@H\Y6K899WT0CBZ)F[F M9L0U@P.\Y&K4`SO522V
F"#D02G:!33052:H0HT=IW1.9WLQCA3: MQ6;>!'C=)G5VIW 1OFH)WW6 M9X')@Q@VBV':)W_VYWAUUTU<@F3Z)X$6:&_!V$WPA($N*(/FE3[`@DU %AJB(.@AJ9D(MB->(IJB*"@6,90(K[,V* MQJB,GL0]0&@JL.6,YJB._D,R8(BG[2B0KN@>9<)\!JF1CN@N4`(\'2F3
6:31FF%WD,J\(:47BF##@,98BF7^F J<_>,-Y 5IJF;2N<[M.F;SBF=UJF=JD9````[ ` end