EX-99.1 2 exhibit99-1.htm ANNUAL INFORMATION FORM OF THE REGISTRANT FOR THE YEAR ENDED MARCH 31, 2012 Exhibit 99.1

Exhibit 99.1



BURCON NUTRASCIENCE CORPORATION
1946 West Broadway
Vancouver, B.C.
V6J 1Z2

ANNUAL INFORMATION FORM
FOR THE YEAR ENDED MARCH 31, 2012

June 25, 2012





TABLE OF CONTENTS

PRELIMINARY NOTES 1
Effective Date of Information 1
Forward Looking Statements 1
Currency 2
Glossary 2
CORPORATE STRUCTURE 3
INTERCORPORATE RELATIONSHIPS 3
GENERAL DEVELOPMENT OF THE BUSINESS 3
Soy 5
Pea 6
Canola 6
DESCRIPTION OF THE BUSINESS 9

Functional Value

9

Nutritional Value

10
Soy 11

Soy Protein

11

CLARISOY

12

Soy Protein Production

13
Pea 14

PEAZAZZ

15
Canola 15

Canola Protein

17

Puratein®

17

Supertein

17

Nutratein

18

Research and Development

18
Objectives 19
Marketing Strategies 20

Plant Protein

21

Soy Protein

22

Pea Protein

23

Canola Protein

23
Intellectual Property 24

Patents

24

Granted U.S. Patents

25

Patent Strategy

26

Trade marks

26

(i)




Facilities 27
Personnel 27
Competitive Conditions 27
Environmental Matters 29
Regulatory Approval For Marketing CLARISOY 29
Regulatory Approval For Marketing PEAZAZZ 31
Obtaining Regulatory Approval For Marketing Puratein®, Superteinand Nutratein 31

United States

32

Puratein® and Supertein

32

Nutratein

34

Human Food

34

Animal Feed

35

Europe

36

Puratein® and Supertein

36

Canada

36

Puratein®, Supertein& Nutratein

36

Nutratein™

38
Estimated Timelines 38
Risk Factors 39

Patents and Proprietary Rights

39

Protection of Intellectual Property is Expensive

40

Early Stage of Development

41

Burcon May Never Achieve Profitability

41

Market Conditions

42

Financing Requirements

42

Product and Market Related Risks

43

Consumer Acceptance

44

Government Regulatory Approval

44

Rapid Technological Change

44

Significant Competition

45

Lack of Commercial Manufacturing Experience

45

Ability to Hire and Retain Key Personnel

45

Reliance on Key Personnel

45

Product Liability

46
DIVIDEND RECORD AND POLICY 46
DESCRIPTION OF CAPITAL STRUCTURE 46
MARKET FOR SECURITIES 46
DIRECTORS AND OFFICERS 47
Directors and Officers 47
Committees 53

(ii)




Aggregate Ownership of Securities 53
Biographies of Directors and Officers 53
Cease Trade Orders, Bankruptcies, Penalties or Sanctions 59
Conflicts of Interest 61
TRANSFER AGENTS AND REGISTRARS 61
MATERIAL CONTRACTS 61
License and Production Agreement with ADM 61
License and Development Agreement with ADM 63
Amendments to License and Development Agreement 64
INTERESTS OF EXPERTS 66
AUDIT COMMITTEE AND DISCLOSURE UNDER NATIONAL INSTRUMENT 52-110 66
Composition of the Audit Committee 66
Audit Committee Oversight 67
Pre-Approval Policies and Procedures 67
External Auditor Service Fees 67
ADDITIONAL INFORMATION 69
GLOSSARY 70
SCHEDULE "A" 72
AUDIT COMMITTEE CHARTER 72

(iii)




PRELIMINARY NOTES

Effective Date of Information

All information in this Annual Information Form ("AIF") is as of March 31, 2012 unless otherwise indicated.

Forward Looking Statements

Certain statements in this AIF may constitute "forward-looking information" which means disclosure regarding possible events, conditions, acquisitions, or results of operations that is based on assumptions about future conditions and courses of action and include future oriented financial information with respect to prospective results of operations, financial position or cash flows that is presented either as a forecast or a projection, and also includes, but is not limited to, statements with respect to the future financial and operating performance of the Company and its subsidiary. Often, but not always, forward-looking statements can be identified by the use of words such as "plans", "proposes", "expects", "is expected", "budget", "scheduled", "estimates", "forecasts", "intends", "anticipates", or "believes" or variations (including negative variations) of such words or phrases, or statements that certain actions, events or results "may", "could", "would", "might" or "will" be taken, occur or be achieved.

Forward-looking statements included or incorporated by reference in this AIF include, but are not limited to, statements with respect to:

  • continued development of Company’s products and business;

  • the Company’s growth strategy;

  • production costs and pricing of CLARISOYsoy protein, PEAZAZZpea protein, Puratein®, Superteinand Nutrateincanola protein isolates;

  • marketing strategies for the Company's soy, pea and canola proteins;

  • development and commercialization for soy, pea and canola proteins;

  • ability to produce proteins and protein isolates in commercial quantities with sufficient grade and quality at cost-effective prices;

  • construction of production facilities;

  • future protection of intellectual property and improvements to existing processes and products;




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  • regulatory approval;

  • input and other costs; and

  • liquidity and working capital.

Forward-looking information involves known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of the Company and its subsidiary to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information. As a result, actual actions, events or results may differ materially from those described in forward-looking information, and there may be other factors that cause actions, events or results to differ from those anticipated, estimated or intended including, without limitation, those referred to in this AIF under the heading "Risk Factors" and elsewhere. Although forward-looking information contained in this AIF is based upon what management of the Company believes are reasonable assumptions, the Company cannot assure investors that actual results will be consistent with the forward-looking information. Forward-looking information contained herein is as of the date of this AIF and the Company disclaims any obligation to update any forward-looking information, whether as a result of new information, future events or results or otherwise, except as required by law. There can be no assurance that forward-looking information will prove to be accurate, as actual results and future events could differ materially from those anticipated. Accordingly, readers should not place undue reliance on forward-looking information due to the inherent uncertainty therein. Material risk factors that could cause actual results to differ materially from the forward-looking information are contained under the heading "Risk Factors" on page 39.

Currency

All dollar amounts in this AIF are expressed in Canadian dollars, unless otherwise indicated.

Glossary

Certain terms used herein are defined in the attached Glossary.




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CORPORATE STRUCTURE

Burcon NutraScience Corporation ("Burcon" or the "Company") was incorporated under the Business Corporations Act (Yukon) on November 3, 1998 under the name "Burcon Capital Corp." and extraprovincially registered in British Columbia on February 5, 1999. Burcon changed its name to "Burcon NutraScience Corporation" on October 18, 1999. The head office of Burcon is located at 1946 West Broadway, Vancouver, B.C., V6J 1Z2. The registered office of Burcon is located at Suite 200, Financial Plaza, 204 Lambert Street, Whitehorse, Yukon, Y1A 3T2.

INTERCORPORATE RELATIONSHIPS

Burcon owns 100% of the issued and outstanding shares of its subsidiary, Burcon NutraScience (MB) Corp. ("Burcon-MB") which was incorporated under the Corporations Act (Manitoba) on February 28, 1992 under the name B.M.W. Canola Inc. Its name was changed to Burcon NutraScience (MB) Corp. on May 30, 2000.

GENERAL DEVELOPMENT OF THE BUSINESS

Burcon was formed in November 1998 as a venture capital pool corporation whose principal business was to identify and evaluate assets, properties or businesses for acquisition. On October 8, 1999 Burcon acquired Burcon-MB.

Since October 1999, Burcon has raised gross proceeds of approximately $49.1 million through the sale of equity securities on both a public and private basis, the exercise of stock options and share purchase warrants, as well as through rights offerings to existing shareholders. This capital has been used, and will continue to be used, to fund research, development, regulatory recognition and commercialization of Burcon’s patented and patent-pending protein extraction and purification technologies. Burcon’s technologies not only enable the production of plant proteins and protein isolates but also relate to applications of the protein produced therefrom into products, including food.

On June 18, 2009, Burcon completed a public offering of 2,942,950 common shares at $5.75 per common share, including 333,950 common shares pursuant to the partial exercise of the agents’ over-allotment option (warrants). The agents received a cash commission of 6% of the gross proceeds and compensation options entitling the agents to purchase up to 117,718 common shares (equal to 4% of the common shares sold pursuant to the offering). Each compensation option was exercisable to acquire one common share of the Company at an exercise price of $5.75 per share at any time before and including December 18, 2010. All compensation options were exercised by the agents prior to the expiry date.




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Concurrent with the completion of Burcon’s 2009 public offering, the Company’s common shares were listed on the Toronto Stock Exchange (the “TSX”). Prior thereto, Burcon’s common shares were listed on the TSX Venture Exchange (the“TSXV”).

On October 27, 2011, Burcon’s common shares commenced trading on The NASDAQ Global Market (“NASDAQ”) under the symbol “BUR”.

The Company’s fiscal year end is March 31. During fiscal 2010 to 2012, Burcon raised a total of $19,779,149 in capital as follows:

  • In June 2009, Burcon completed a short form prospectus offering and raised gross proceeds of $16,921,963 as described earlier.

  • During fiscal 2010, Burcon raised $410,084 through the exercise of options by directors, officers, employees and consultants.

  • During fiscal 2010, Burcon raised $35,886 through the exercise of certain agent options granted pursuant to the June 2009 short form prospectus offering.

  • During fiscal 2011, Burcon raised $1,225,900 through the exercise of options by directors, officers, employees and consultants.

  • During fiscal 2011, Burcon raised $640,993 through the exercise of certain agent options granted pursuant to the June 2009 short form prospectus offering.

  • During fiscal 2012, Burcon raised $544,323 through the exercise of options by directors, officers, employees and consultants.

The proceeds raised from the public offering, exercise of warrants and options described above have been used to:

  • further develop Burcon’s protein extraction and purification technologies and pursue new related products;

  • pursue functionality development initiatives relating to Burcon’s proteins;

  • fund Burcon’s patent activities;

  • prepare for and fund scientific studies and related costs associated with regulatory recognition of Burcon’s canola proteins for human consumption;




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  • fund the activities associated with identifying, negotiating terms and securing a strategic alliance, including the License and Production Agreement with Archer Daniels Midland Company, for the commercialization of Burcon’s CLARISOYsoy protein;

  • fund the activities associated with identifying, negotiating terms and securing a strategic alliance for the commercialization of Burcon’s PEAZAZZpea protein; and

  • provide general working capital.

Soy

Soy protein isolate is used as a functional ingredient or fortifier in a wide variety of food products including protein shakes, power bars, soups and sauces, meats and meat analogs, and breads and baked goods. In addition to enhancing the protein content of foods, soy protein isolates are used by food manufacturers for their functional applications. These applications include the ability to emulsify, whip, bind and add viscosity to foods. See "Description of the Business".

Burcon has developed technologies to extract and purify soy protein from a variety of soy materials. These technologies encompass various processes to produce a soy protein which Burcon has branded as "CLARISOY". CLARISOYsoy protein is a unique soy protein which is 100% soluble and transparent in applications with a pH of 4.0 and below. CLARISOYis specifically designed to enable beverage manufacturers to meet the demand for great-tasting, nutritionally enhanced beverages targeted to the ever-growing number of health and wellness minded consumers. Unique to any other proteins on the market, CLARISOYis the only vegetable-based protein that offers clarity and complete protein nutrition for low pH beverage systems. Potential beverage applications for CLARISOYinclude: sports nutrition beverages, citrus-based drinks, fruit-flavoured beverages, lemonades, powered beverage mixes, fruit juice blends and fortified waters.

During fiscal years 2009 and 2010, Burcon entered into material transfer agreements and non-disclosure agreements with a number of globally recognized food, beverage and nutritional product companies for the evaluation of CLARISOYsoy protein with the objective of entering into a strategic alliance or a strategic partnership to produce, market and sell CLARISOYsoy protein .

The process of pursuing a strategic alliance partner or partners for the development of CLARISOYsoy protein focused on partnering for the production of CLARISOYas well as the marketing and sale of CLARISOYto food and beverage manufacturers. Burcon held discussions with a number of entities who expressed an interest in partnering – in most cases exclusively - for the sale of CLARISOYsoy protein to food and beverage manufacturers and nutritional




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supplement companies. Certain parties also expressed an interest in partnering for the production of CLARISOYsoy protein.

On November 12, 2010, Burcon entered into a non-binding letter of intent with ADM which detailed the intention of the two parties to enter into a license agreement pursuant to which Burcon would license its CLARISOYsoy protein technology to ADM on a worldwide, exclusive basis to produce, market and sell soy protein products using Burcon’s CLARISOYsoy protein technology. The parties agreed to negotiate and execute the definitive agreement setting forth the terms and conditions of the license on or before March 1, 2011 or such later date as agreed by the parties. See “Material Contracts”.

On March 4, 2011, Burcon, Burcon-MB and ADM entered into the License and Production Agreement for the worldwide, exclusive production, marketing and sale by ADM of soy protein products using Burcon’s CLARISOYsoy protein technology. See “Material Contracts”.

Pea

Pea protein is a relatively new, vegetable-based, functional protein ingredient valued for its emulsifying properties. Pea proteins currently available in the market are sold for use in a variety of food products including: snacks and cereals; diet products (high protein foods); gluten-free and vegetarian and vegan foods.

In November 2011, Burcon announced that it had developed a novel pea protein which it has branded as “PEAZAZZ”. PEAZAZZ™ is 100% soluble and transparent in low pH solutions with clean flavour characteristics. It is heat stable permitting hot fill applications. See “Description of the Business”.

Until April 2012, Burcon held exclusive negotiations with a potential partner to commercialize PEAZAZZand the associated protein extraction technology. On April 23, 2012, Burcon announced that although discussions with this potential partner are ongoing, the exclusivity period had lapsed. Therefore, Burcon will consider additional routes-to-market for its PEAZAZZpea protein.

Canola

Burcon extracts and purifies three types of canola protein isolates from canola meal, a co-product (together with canola oil) of the canola seed crushing industry. Burcon has branded these protein isolates under the trade names "Puratein®", "Supertein" and “Nutratein”.

The goal of Burcon’s research is to develop its patented and patent-pending processes to utilize inexpensive oilseed meals for the production of purified plant proteins that exhibit nutritional, functional or nutraceutical profiles. Burcon expects that Puratein® canola protein isolate and Superteincanola protein isolate will




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participate and compete with soy, dairy, and egg proteins in the expanding global protein ingredient market, with potential uses in prepared foods, nutritional supplements and personal care products. Nutrateinis expected to initially participate in the animal feed and nutrition category.

On September 16, 2003, Burcon and Burcon-MB entered into a license and development agreement (the "License and Development Agreement") with ADM to commercialize Burcon’s canola protein ingredients, including Puratein® canola protein isolate and Superteincanola protein isolate. See “Material Contracts”.

The License and Development Agreement set forth the process by which the two parties would carry out the final development of Burcon’s technology to produce Puratein® canola protein isolate and Superteincanola protein isolate. The License and Development Agreement contemplated that ADM would develop applications for Puratein® canola protein isolate and Superteincanola protein isolate, obtain regulatory approvals, construct one or more full-scale production facilities and have the exclusive right to produce, promote, market and sell Puratein® canola protein isolate and Superteincanola protein isolate worldwide.

Upon completion of the development period set out in the License and Development Agreement and the parties’ agreement on the royalty rate and minimum royalties payable by ADM during the term of the License and Development Agreement, it was anticipated that the Company would grant ADM an exclusive, royalty-bearing, worldwide license to use and exploit the Company’s technology solely to make, have made, use, import and sell the Company’s products, together with certain rights to grant sublicenses. It was anticipated that ADM would pay to the Company royalties based on sales of products by ADM, its affiliates and sublicensees.

On June 19, 2007, Burcon announced that it had agreed to amend the License and Development Agreement with ADM (the “First Amendment”). Under the terms of the First Amendment, the parties agreed to jointly fund the third-party expenses required in order to obtain "generally recognized as safe" or "GRAS" status for Puratein® canola protein isolate and Superteincanola protein isolate. GRAS status is the regulatory recognition process established in the United States by the U.S. Food and Drug Administration ("FDA"). See "Obtaining Regulatory Approval for Marketing Puratein® and Supertein." The total cost of the regulatory process was estimated at approximately US$977,000. Under the amendment, Burcon and ADM each contributed one-half of the expenses up to US$720,000. Burcon further agreed to contribute any additional amounts in excess of US$720,000, subject to a maximum of US$1,033,000 in the total cost for the regulatory process. The parties agreed to negotiate in good faith to determine each party’s obligation to contribute further funding should the cost for the regulatory process exceed US$1,033,000. A total of US$946,000 was expended, with Burcon’s share at US$586,000.




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The First Amendment provided that either ADM or Burcon would reimburse the other on the occurrence of certain events. If ADM chose not to proceed with the license under the License and Development Agreement and terminated it in accordance with the specific provisions under the agreement, then Burcon would reimburse ADM for its share of the costs incurred in the regulatory process. Alternatively, if ADM chose to proceed with the license then ADM would reimburse Burcon for all of its costs incurred in the regulatory process.

On October 7, 2008, Burcon announced that its Puratein® canola protein isolate and Superteincanola protein isolate achieved self-affirmed GRAS status for their intended use in a variety of food and beverage applications in the United States and can market and sell the products for human consumption in the United States. GRAS is an FDA designation that a substance added to food is generally recognized, among experts qualified by scientific training and experience to evaluate its safety, as having been adequately shown through scientific procedures (or, in the case of a substance used in food prior to January 1, 1958, through either scientific procedures or through experience based on common use in food) to be safe under the conditions of its intended use.

On January 19, 2010, Burcon announced that it had filed a formal notification in accordance with the FDA proposed regulation 62FR 18938, having determined, based on a review of the data referenced in the notification, that Burcon’s Puratein® canola protein isolate and Superteincanola protein isolate are GRAS for their intended use as an ingredient in a variety of food and beverage applications and in addition, that both substances are exempt from premarket approval requirements of the Food, Drug and Cosmetic Act (the “GRAS Notification”). In response to comments from the FDA, Burcon modified and resubmitted the GRAS Notification in February 2010. In a letter dated April 1, 2010, the FDA formally acknowledged receipt of the GRAS Notification. See "Obtaining Regulatory Approval for Marketing Puratein®, Superteinand Nutratein".

On August 30, 2010, Burcon announced that the FDA issued a no objection letter with respect to Puratein® and Superteincanola protein isolates. This response indicates that the FDA has no objection to the conclusion that Puratein® and Superteinare GRAS among qualified experts for use alone or together as an ingredient in dairy products, grain products, fruit and vegetable juices and beverages, salad dressings, meal replacements and nutritional bars. See "Obtaining Regulatory Approval for Marketing Puratein®, Superteinand Nutratein".

Burcon and ADM entered into an agreement dated as of November 11, 2010 amending the License and Development Agreement (the “Second Amendment”). The Second Amendment protected Burcon’s and ADM’s interests under the License and Development Agreement while the two parties worked to negotiate the terms of the proposed license agreement for Burcon’s CLARISOYsoy protein.




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On March 4, 2011, Burcon and ADM agreed to a further amendment of the License and Development Agreement (the “Third Amendment”) for a one-year extension to March 1, 2012 to provide an extended development period for continued research aimed at expanding the commercial value of Puratein® and Superteincanola protein isolates. However, the parties did not reach an agreement prior to March 1, 2012. Therefore, the License and Development Agreement between Burcon and ADM has terminated. In April 2012, Burcon reimbursed ADM in the amount of US$360,000, representing ADM’s share of the costs expended in the regulatory process. See “Material Contracts”.

Given the termination of the License and Development Agreement, Burcon is free to choose alternative paths for the commercialization of its technology for the production of its canola proteins: Puratein®, Supertein™ and Nutratein. Burcon is working with potential customers to establish the commercial value of all three of these canola proteins. In the case of Puratein® and Supertein™ canola protein isolates, Burcon continues to work with food and beverage manufacturers to establish the value of Burcon’s proteins in their food products. Burcon has executed material transfer agreements with certain major companies. In the case of Nutrateincanola protein isolate, Burcon is pursuing an animal nutrition application with a leading animal feed company with the intention of using Nutrateincanola protein isolate to replace or partially replace dairy protein in certain high-value animal feed applications.

DESCRIPTION OF THE BUSINESS

The protein ingredient industry continues to experience rapid growth, with plant proteins in particular experiencing high demand. This increase in demand for plant proteins is fuelled in part by scientific advances, changing demographics as well as by the public’s changing perception of the safety of animal-based products. External issues such as melamine tampering/contamination, mad cow disease, E. coli, swine flu and the growing use of antibiotics in animal production, as well as demographic trends are all combining to produce significant demand for plant proteins.

Two major attributes are relevant to the commercial value of protein as an ingredient: functional value and nutritional value.

Functional Value

Proteins possess a wide range of attributes essential to the structure and textural integrity of food products. These relevant properties include: solubility, viscosity, water-binding, gelation, cohesion, adhesion, elasticity, emulsification, foaming, whipping, fat-binding and flavour-enhancing qualities.




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In weighing the commercial potential of any protein ingredient, functional utility is at least as important as nutritional value. For example, although the nutritional value of wheat protein is comparatively low, (the Protein Digestibility Corrected Amino Acid Score (“PDCAAS”) of whole wheat is 0.40, see "Soy – Soy Protein and Canola – Canola Protein"), only wheat protein—called gluten—will make a traditional loaf of bread. Thus, the functionality of wheat protein makes it a staple in the North American diet. At the top end of the functional scale, egg white protein will whip, coagulate, and form films. Such functional versatility makes egg white one of the most valuable food proteins. Certain of Burcon’s proteins can be made to mimic many of egg’s functions, and in certain instances can outperform egg.

Nutritional Value

Proteins are organic compounds made up of carbon, hydrogen, oxygen and nitrogen. It is the presence of the nitrogen that sets proteins apart from other nutrients. Nitrogen is essential to human life, but since we have no other source of nitrogen—unlike plants, we are unable to absorb it as a nutrient from the ground—one of the most important roles of dietary protein is to bring nitrogen into the body.

Proteins are made up of sub-units called amino acids. There are twenty dietary amino acids, typically subdivided into two categories: non-essential amino acids, which can be made within the body, and essential amino acids which must come from diet.

Amino acids supplied from dietary protein are needed for synthesis of body proteins in muscle, organs, bone and skin, and for synthesis of enzymes, certain hormones, antibodies and a host of bodily processes.

The essential amino acids are lysine, methionine + cysteine, threonine, tryptophan, leucine, isoleucine, valine, phenylalanine, arginine and histidine (adults do not require a dietary supply of arginine).

A diet deficient in one or more of the essential amino acids impairs growth in children, causes adults to lose muscle mass, and lowers the body's resistance to a variety of diseases. Extreme protein deficiency can be a cause of death. An adequate daily supply of high-quality protein is essential to optimal growth and health.

The nutritional supplements industry has seen rapid growth in the use of protein ingredients over the past ten years. Protein bars, once consumed only by endurance athletes, are now widely available and protein-rich meal-replacement products and dietary supplements have become supermarket staples. Protein supplements are also increasingly and successfully being promoted to the expanding market of geriatric consumers. Potential nutritional applications for




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protein isolates include power shakes, protein bars, protein powders and any other concentrated protein supplement.

Soy

The soybean had its beginnings in China. Chinese historical documents suggest that soybeans have been a diet staple in Asia since the 11th Century BC. According to the Soyfoods Association of North America, the soybean was introduced to North America around the 1760s. Today, soybeans are grown in many parts of the world with the United States being the largest producer of this crop, followed by Brazil, Argentina and China. The United States Department of Agriculture notes that the value of U.S. soybean production in 2010 was approximately US$37.6 billion, which represented the second-highest value among U.S. produced crops, behind corn. Soybeans are similar in size and colour to peas and are primarily cultivated for their oil and protein. Soybeans are the largest single source of edible oil and accounted for over 50% of the world’s total oilseed production in 2010. In addition to being a source of oil and protein, soybean meal is used in animal feed for the production of meat and eggs.

Each soybean is comprised of approximately 40% protein, 35% carbohydrate (including fiber), 20% oil, and 5% ash.

Soy Protein

Commercially sold soy protein is available in predominantly three forms: soy flour, soy concentrates and soy protein isolates. After cracking and dehulling the soybean, soy processors roll them into flakes. Oil from the soybean flakes is removed and then the flakes are dried. The defatted flakes are then further processed into soy protein.

Soy protein isolate is the purest of the three forms of soy protein and contains over 90% protein, on a moisture free basis. Soy protein isolates are relatively neutral in flavour and odour and are used primarily by the food industry. Today, soy protein isolate is used in a variety of food applications, including as a protein replacement for dairy proteins in food or in products such as protein shakes, power bars, soups and sauces, meat analogs, breads and baked goods. Soy protein isolates are desired by food manufacturers for their functional applications. These applications include the ability to emulsify, whip, bind and add viscosity to foods.

In addition to its functional attributes, soy protein isolate provides nutritional enhancement to foods. Soy protein contains all the essential amino acids required for human nutrition.

Numerous studies have been conducted on the health benefits of soy protein. In October 1999, the FDA approved a health claim for soy protein and its role in




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reducing the risk of coronary heart disease. Food manufacturers may label foods containing soy protein by stating that "Diets low in saturated fat and cholesterol that include 25 grams of soy protein daily may reduce the risk of heart disease. One serving of (name of food) provides __ grams of soy protein." To qualify for the claim, the food must contain per serving:

  • 6.25 grams of soy protein;

  • low fat (less than 3 grams);

  • low in saturated fat (less than 1 gram);

  • low in cholesterol (less than 20 milligrams); and

  • sodium value of less than 480 milligrams for individual foods, less than 720 milligrams if considered a main dish, and less than 960 milligrams if considered a meal.

The quest for healthier lifestyles has led consumers to search for healthier alternatives to animal protein. The FDA’s approval of a health claim for soy protein has fuelled soy protein’s increasing popularity and general acceptance among consumers. These factors are expected to sustain market demand for soy protein isolates. Burcon intends to participate in this growing market through its CLARISOYsoy protein.

CLARISOY

In November 2008, Burcon announced that it had developed a soy protein which it branded as CLARISOY. CLARISOYsoy protein is 100% soluble, transparent and heat stable in applications with a pH of 4.0 and below. CLARISOYis specifically designed to enable beverage manufacturers to meet the demand for great-tasting, nutritionally enhanced beverages targeted to the ever-growing number of health and wellness minded consumers. Unique to any other proteins on the market, CLARISOYis the only vegetable-based protein that offers clarity and complete protein nutrition for low pH beverage systems. Potential beverage applications for CLARISOYinclude: sports nutrition beverages, citrus-based drinks, fruit-flavoured beverages, lemonades, powdered beverage mixes, fruit juice blends and fortified waters.

Processes used in the production of common and traditional soy protein isolates involve the use of harsh caustics and acids to separate the soy proteins from the other constituents of defatted soy. This harsh chemical treatment causes some denaturation of the soy proteins resulting in a lack of solubility and stability in aqueous products and, notably, a lack of solubility in acid beverages (juices, sport energy drinks, fortified waters, flavoured waters etc.). Burcon has developed and




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filed for patent protection over novel processes allowing for uniquely soluble soy proteins.

Based on the recommendations of the Joint Expert Consultation of the Food and Agricultural Organization ("FAO") and World Health Organization ("WHO") in 1989, the FDA and the FAO/WHO adopted in 1993 the PDCAAS as the preferred method for measuring the quality of a protein based on the amino acid requirements of humans. The PDCAAS method for evaluating protein quality is based on the needs of humans. The quality of a protein is based on the amino acid requirements of a 2 to 5 year old child, which is considered to be the most nutritionally demanding age group, other than infants. After adjusting for digestibility, the protein quality rankings of a specific protein evaluated under the PDCAAS method are compared to a standard amino acid profile with the highest possible score being a 1.0. A PDCAAS score of 1.0 means that, after digestion of the protein, it provides 100% or more of all the essential amino acids required. Proteins with a PDCAAS of 1.0 include egg and cow’s milk.

The PDCAAS scoring system has since been updated by the FAO/WHO/United Nations University ("UNU") in 2002, altering the reference amount of specific amino acids and also dividing the requirement by age groups of children 1-2 years and 3-10 years. In the Report of a Joint FAO/WHO expert consultation on protein and amino acid requirements in human nutrition, the FAO/WHO/UNU came to the conclusion that previous reports considerably overestimated the protein requirements. Despite the foregoing, the FDA has neither formally adopted the updated levels recommended in the 2002 report nor advised food companies to use these updated levels when calculating PDCAAS values.

Based on the PDCAAS method, Burcon’s CLARISOYsoy protein has a score of 0.98 and 1.00 under the 1989 FAO/WHO pattern and the 2002 FAO/WHO/UNU pattern, respectively, suggesting that Burcon’s CLARISOYsoy protein is a good protein source.

Soy Protein Production

Pursuant to the terms of the License and Production Agreement (see “Material Contracts”), Burcon has licensed its CLARISOYsoy protein technology to ADM, on an exclusive basis, to use, market and sell the products (the “Soy Products”) that use the CLARISOYtechnology. Under the License and Production Agreement, ADM will be the primary party responsible for the commercialization efforts for CLARISOY, including:

  • developing the necessary process engineering for scaling up the production of the Soy Products;




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  • developing applications for the Soy Products; and

  • designing, building and commissioning an initial production facility (the “Semi-works Production Facility”) to manufacture the Soy Products.

ADM will also, within a time specified under the License and Production Agreement, provide written notice to Burcon to advise whether it will or will not increase its annual production capacity of the Soy Products beyond the capacity of the Semi-works Production Facility (“Full Commercial Production”). The License and Production Agreement provides each party the right to convert the exclusive license to a non-exclusive license under certain conditions. If the exclusive license is converted to a non-exclusive license, Burcon will be entitled to make, have made, use, market and sell the Soy Products on a non-exclusive basis and to grant any such rights to any other person.

During the term of the license under the License and Production Agreement, Burcon will continue to refine its protein extraction and purification technology for soy protein in its Winnipeg Technical Centre. In addition, the Winnipeg Technical Centre will produce samples of CLARISOYsoy protein for ADM to facilitate the commercialization process.

Pea

Field pea, or Pisum sativum in Latin, is part of the legume family and was one of the earliest cultivated food crops. A pea is most commonly the green or yellow small spherical seed inside a peapod that contains multiple peas. The pea plant is grown in cool-weather conditions in many parts of the world, including Canada, Europe and Asia.

Peas are consumed as a vegetable worldwide for their high nutritional value and health benefits. Not only are peas high in protein, fibre, starch, vitamins and minerals, but they are also non-allergenic and environmentally sustainable. As part of the legume family, pea plants have the ability to lock in nitrogen from the atmosphere and store it in their root nodules. This nitrogen-fixation ability allows producers to use less fertilizer and replenish the soil with nitrogen, making peas a much desired sustainable crop.

In November 2011, Burcon announced that it had developed a novel pea protein which it has branded as “PEAZAZZ”. Burcon has developed its first technology platform to extract added-value proteins from a non-oilseed source. Burcon’s technology extracts and purifies a novel pea protein from field peas. Both the nutritional and functional characteristics of pea protein allow for a host of great tasting food and beverage product applications.




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Pea protein is a relatively new, vegetable-based, functional protein ingredient. Pea proteins currently available in the market are sold for use in a variety of food products including: snacks and cereals; diet products (high protein foods); gluten-free and vegetarian and vegan foods.

PEAZAZZ

PEAZAZZpea protein is 100% soluble, transparent and heat stable in low pH solutions. PEAZAZZhas clean flavour characteristics and is well suited for use in low pH beverages as well as a variety of other healthy and great tasting food and beverage product applications. Its valuable nutritional and functional characteristics make PEAZAZZan attractive product to companies looking for an alternative plant protein ingredient.

Pea is a widely accepted and consumed vegetable, recognized for its nutritional value and health benefits. Burcon has successfully extracted added-value proteins that contain essential amino acids into a white powder that can easily be incorporated into a variety of foods and beverages including low pH fruit juices and juice blends, sport nutrition drinks, powdered beverages, fortified waters, bars, baked goods and vegetarian and vegan foods.

Burcon’s PEAZAZZpea protein is non-allergenic and can be produced from a non-GMO source.

Pea proteins currently available on the market are sold for use in a variety of food products including: snacks and cereals; high-protein weight management products; gluten-free and vegetarian and vegan foods. Burcon is not aware of any pea protein isolate in the market that is 100% soluble. Burcon expects the introduction of PEAZAZZpea protein to be able to gain a share of the pea protein market, as well as expand the pea protein market to include (what it previously could not) a broader range of product applications such as low pH beverages.

Burcon has held initial discussions with a number of potential partners for the commercialization of its new PEAZAZZpea protein technology. Many alternative business structures are being considered, but no definitive structure has been determined to date.

Canola

Canola is the North American name for the enhanced variation of rapeseed first developed and introduced in 1974 when a Canadian researcher bred a "double low" variety of rapeseed with reduced levels of the two negative factors naturally occurring in rapeseed: erucic acid and glucosinolates. This type of rapeseed is known in Europe and parts of Asia as rapeseed or oilseed rape and has become the



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world’s second largest oilseed crop. The growth of rapeseed as an international crop can be attributed to three factors: the ability to grow rapeseed in temperate climates; favourable production costs; and a beneficial fatty acid profile for the oil, which is high in monounsaturates.

Each canola plant produces yellow flowers which produce pods that are similar in shape to pea pods and about 1/5th the size. Within the pods are tiny round seeds that are crushed to obtain canola oil. After the oil is removed through processing at a canola crushing plant, the remainder of the seed (approximately 60% by weight) is canola meal. Canola meal is the raw material from which Burcon intends to extract protein commercially to produce Puratein® canola protein isolate, Superteincanola protein isolate and Nutrateincanola protein isolate. Canola meal is comprised of approximately 35% protein. Canola meal is in abundant and relatively inexpensive supply and is sold almost exclusively as an animal feed ingredient; however, its protein value, even in feed applications, is limited by the presence of a large amount of fiber and other anti-nutritional factors naturally present in canola seed. Burcon’s extraction process separates the protein from the fiber and from most of the naturally occurring anti-nutritional factors.

In the past, numerous attempts have been made at finding an economically viable method to extract canola protein from canola meal. There is a significant amount of scientific publications that describe various methods to do so, most of which publications also underscore numerous reasons for the scientific interest in obtaining canola protein isolate, including, amongst others: a unique amino acid profile, rich in sulfur containing amino acids; an abundant source of protein; and two distinct protein fractions. However, none of the existing technologies described in the scientific literature is commercially applied at present. Major drawbacks of the existing technologies, which often use alkaline extraction followed by isoelectric precipitation, include the insufficient purity of the canola protein isolate, unacceptable colour and taste of the canola protein products as well as the resulting protein’s limitations regarding functionality. Phenolics that are naturally present in canola oxidize readily in alkaline conditions causing dark coloration of the final protein product.

Burcon’s canola protein extraction process does not use harsh chemicals but rather is based primarily on making use of physical separation and purification techniques. At the core of Burcon’s canola protein isolate production process is a micelle formation step, which separates the two naturally occurring proteins in canola: napin and cruciferin. Processing of these two fractions results in the cruciferin-rich canola protein isolate Puratein® canola protein isolate and the napin-rich canola protein isolate Superteincanola protein isolate. Burcon has also developed Nutrateincanola protein isolate, which consists of a blend of the two fractions.




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Canola Protein

Potential nutritional applications for canola protein isolates include power shakes, protein bars, protein powders and any other concentrated protein supplement.

Based on the PDCAAS method, the PDCAAS scores for Burcon’s canola proteins are as follows:

Canola Protein Isolate FAO/WHO 1989
mg/g protein
(2-5 years old)
FAO/WHO/UNU 2002
mg/g protein
(3-10 years old)
Puratein® 0.60 0.72
Supertein 0.71 0.91
Nutratein 0.90 1.00

Burcon’s canola protein has a score in the range of 0.60 to 0.90 under the 1989 FAO/WHO pattern and a score in the range of 0.72 – 1.00 under the 2002 FAO/WHO/UNU pattern, suggesting that Burcon’s canola protein is a good protein source.

Puratein®

Puratein® canola protein isolate’s key functionalities are emulsifying, gelling and binding. Puratein® canola protein isolate has potential in a wide variety of food types.

Puratein® canola protein isolate is a canola protein isolate comprised mainly of globulin proteins. The functional properties of Puratein® canola protein isolate include emulsification, gel formation, thickening, formation of heat-stable foams, and water- and ingredient-binding. Applications for Puratein® canola protein isolate include dressings and sauces, meat substitutes, baked goods and protein bars. Puratein® canola protein isolate has good taste characteristics with no off-flavours.

Supertein

Superteincanola protein isolate is a highly soluble canola protein isolate comprised principally of albumin proteins. The functional properties of Supertein




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canola protein isolate include solubility, the ability to form transparent solutions, foaming and nutrition. Applications for Superteincanola protein isolate include beverages, confectionery, aerated desserts, and protein bars, among many others. Superteincanola protein isolate has a slightly sweet taste with no off-flavours.

The exceptional cysteine content of canola protein (rapeseed protein) has long been of interest to nutritional scientists. A potential link between canola protein’s high cysteine content and disease prevention has been reported in a study in the British Journal of Nutrition entitled “Rapeseed protein inhibits the initiation of insulin resistance by a high-saturated fat, high-sucrose diet in rats” by Mariotti F. , Hermier D., Sarrat C., Magné J., Fénart E., Evrard J., et al 2008 Nov; 100(5):984-91. The study’s aim was to determine whether rapeseed protein, described by the study’s authors as “an emergent cysteine-rich protein” could inhibit the onset of the metabolic syndrome. The main finding of the study “is that rapeseed protein substituted for milk protein inhibited the onset of insulin resistance in rats fed the high-saturated fat, high-sucrose diet”. The authors further noted that rapeseed protein mitigated certain factors associated with metabolic syndrome: “The study’s result highlights the importance of the type of protein as a major component of diet quality, in terms of cardiovascular and diabetic risks.”Superteincanola protein isolate is rich in sulfur amino acids and particularly rich in cysteine. The typical cysteine content of Burcon’s Superteincanola protein isolate is nearly double that of whey protein, which is recognized for its high cysteine content. The findings in the study reported in the British Journal of Nutrition suggest that Superteinmay have potential applications in the prevention of metabolic syndrome.

Nutratein

Nutrateinis a canola protein isolate comprised of a mixture of globulin and albumin proteins. Nutrateinis a fine powder that has good solubility across a broad pH range. Nutrateinhas an excellent amino acid profile and its PDCAAS score makes it a suitable replacement for existing proteins in the animal feed and nutrition industry. Burcon is pursuing an animal nutrition application with a leading animal feed company with the intention of using Nutrateincanola protein isolate to replace or partially replace dairy protein in certain high-value animal feed applications. Applications in human nutrition include protein bars, meat applications, baked goods or nutritional beverages. Nutrateincanola protein isolate is bland in taste with no off-flavours.

Research and Development

Burcon has designed and built a large-scale pilot production facility, complete with an analytical laboratory, for the development and small-scale production of proteins from various plant sources.




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Burcon has over 13 years of experience in developing high-quality vegetable protein ingredients and has successfully developed CLARISOYsoy protein and is developing PEAZAZZpea protein and three unique canola protein isolates, Supertein, Puratein® and Nutrateincanola protein isolates After years of research on developing these products to meet Burcon’s expectations of commercial quality standards, experience and know-how has been amassed in running large-scale pilot operations.

Objectives

For fiscal year 2013, Burcon’s main objectives are to further the development and commercialization of its pea and canola products. In addition, Burcon will also:

  • continue to refine its protein extraction and purification technologies, develop new technologies and related products;

  • further strengthen and expand its intellectual property portfolio;

  • support ADM in connection with its development of CLARISOYsoy protein products; and

  • explore opportunities for acquiring or licensing into Burcon, novel technologies that will complement or enhance Burcon’s intellectual property portfolio and business initiatives.

Burcon’s pea product development and commercialization objectives include:

  • continuing to file patent applications to protect the PEAZAZZpea protein process as well as the composition and applications for PEAZAZZpea protein into food products;

  • conducting further research to develop additional applications for PEAZAZZpea protein into food products; and

  • negotiating with potential strategic alliance partners to commercialize PEAZAZZpea protein.

Burcon’s canola product development and commercialization objectives include:

  • refining the Nutrateincanola protein isolate pilot process to produce a consistent product of optimum quality, flavour, colour, aroma, amino acid profile, nutritional and functional attributes;




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  • collaborating with animal feed manufacturers on animal and/or fish feeding trials using Nutrateincanola protein isolate;

  • further research and development to establish the unique functional and nutritional characteristics of Superteinand Puratein® canola protein isolates.

  • pursuing product development agreements with major food, beverage and nutritional product companies to develop improved or novel applications for Supertein™, Puratein® and Nutrateincanola protein isolates into their products; and

  • pursuing a strategic alliance with a potential partner in connection with the development of a commercial facility for the production, marketing and sale of Burcon’s canola protein isolates.

Marketing Strategies

Burcon’s CLARISOYsoy protein, PEAZAZZpea protein, Puratein®, Superteinand Nutrateincanola protein isolates are expected to compete with soy, whey, milk and egg proteins in the expanding global multi-billion dollar protein ingredient market. Burcon’s proteins are expected to specifically compete with whey protein isolates, casein/caseinates and dried egg-white as well as with existing traditional soy and pea proteins.

Food Business News reported the following average prices for the major protein ingredients that Burcon expects its products to compete with:

Whey protein isolate US $5.10 /pound1 CDN $11.50/kg. 2
Casein/caseinates US $5.05 /pound3 CDN $11.38/kg. 2
Dried Egg-white US $4.80 /pound3 CDN $10.82/kg. 2

Soy and pea protein prices are not readily available to the public. However, through discussions with industry participants and market data research, Burcon management estimates that soy protein isolate and pea protein isolate prices are approximately as follows:

Soy protein isolate US $3.50 /pound CDN $7.89 /kg.2
Pea protein isolate US $2.50 /pound CDN $5.64 /kg. 2

Notes:

1. Price based on last available listing in Food Business News (November 22, 2011 edition). There is no current available price listing for whey protein isolate (90% edible).




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2. Conversion into Canadian dollars made by Burcon, based on Bank of Canada exchange rate of C$1.00 = US$0.9776 on May 29, 2012.

3. Prices based on the May 8, 2012 edition of Food Business News for the week ending May 4, 2012.

Burcon expects the average selling price of PEAZAZZpea protein to achieve an average price level that would equate to a premium over current pea pricing and at a significant discount to the animal-based proteins (whey, casein and egg). Burcon expects the cost to produce PEAZAZZpea protein to be materially consistent with the cost to produce traditional soy protein isolates.

Pursuant to the License and Production Agreement, ADM has the sole discretion in developing the sales and marketing strategies for CLARISOYsoy protein. Given ADM’s extensive experience in the sale and marketing of soy protein products, Burcon expects that CLARISOYwill be strategically priced amongst ADM’s current product portfolio and other competing protein products in the global market.

Plant Protein

According to Frost & Sullivan, the U.S. protein-ingredients market was forecast to generate nearly US$4.5 billion in revenues in 2008 (approximately 43.3% plant proteins and 56.7% animal proteins by revenue) and is expected to continue to grow at a compounded annual growth rate of 4.5% to 2014. In the U.S. alone, approximately 2.5 billion pounds of protein ingredients are forecast to have been consumed in 2008. Perhaps more importantly from Burcon’s perspective, revenues of plant protein ingredients are projected to grow at an even faster rate. In 2008, plant protein consumption accounted for approximately 73.6% of the total protein consumed in the U.S. on a tonnage basis. .

Plant proteins are experiencing significant sales growth in North America and Western Europe for a variety of reasons. Changing demographics is one reason for this trend as nutrition-conscious baby boomers become aware of the health benefits of protein in general and, more specifically, of the benefit of plant proteins over certain animal proteins. Food manufacturers in turn are motivated by simple economics to prefer inexpensive plant proteins over their more costly animal counterparts.

Near-vegetarians, a growing group of consumers who choose meatless meals regularly but not exclusively, are also contributing to the trend favoring plant proteins. Responding to this new demographic, food manufacturers are taking advantage of the functional merits of plant proteins to create meat-free, high-protein foods.




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While the demand for plant proteins is being driven by the health and wellness trend in the developed world, a possibly even larger force shaping the global protein ingredient industry is the growth of the middle class consumer in the developing world. During the past number of years, there has been a marked increase in demand for, and the price of, all protein ingredients. The growth of the middle class in the BRIC countries (Brazil, Russia, India and China) has been noted by many observers as being the key factor in that demand increase. As consumers evolve from a subsistence living to earning incomes where – in their respective countries - they can be classified as middle class, they invariably spend a large portion of their new income on food.

Casein and whey, the two major dairy protein ingredients, have experienced a particularly dramatic price increase in the past number of years as compared to historical averages. The major soy protein producers, led by Solae LLC ("Solae"), have in turn increased the price of their soy proteins during the same period albeit to a lesser extent.

In addition to the health and wellness trend in the developed world and the expanding middle class in the developing world, plant proteins are gaining popularity from the recognition that they offer a more environmentally friendly alternative to animal derived proteins. Consumers are considering the environmental footprint a product makes when making their purchase decisions. Production of animal proteins is viewed as less "environmentally economic" when compared to the production of plant proteins. Producers must feed plant protein to animals in order to produce animal proteins and animals are not efficient converters, pound for pound, of the proteins they consume. There is also a growing awareness of the large amount of greenhouse gases generated globally through livestock production.

Lastly, health concerns caused by melamine tampering/contamination, swine flu, E. coli, Asian bird flu and mad cow disease have provoked consumer concern that animal-based protein products may be unsafe.

Soy Protein

Frost & Sullivan estimated that in 2008, the United States soy protein market alone generated revenues of approximately US$1.6 billion and projects revenues to reach about US$2.1 billion by 2014. Sales of soy protein isolates alone – the highest quality of soy protein available commercially – were estimated by Frost & Sullivan at approximately US$798 million in 2008, which represented approximately half of the total revenues from the U.S. soy protein market.

As discussed above, ADM has the sole discretion in developing the sales and marketing strategies for CLARISOYsoy protein pursuant to the License and




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Production Agreement. Given ADM’s extensive experience in the sale and marketing of soy protein products, Burcon expects that CLARISOYwill be strategically priced amongst ADM’s current product portfolio and other competing protein products in the global market.

Pea Protein

The following chart illustrates the annual global production of dried peas (in tonnes) from 2004 to 2010 as estimated by the FAO:

  2004 2005 2006 2007 2008 2009 2010
Canada       3,097,200       2,993,600 2,519,900 2,934,800       3,571,300       3,379,400       2,862,400
United States          517,957          635,165        598,880        738,766          556,560          777,320          645,050
Western Europe       2,302,205       1,801,179 1,421,119        853,789          661,885          773,908       1,332,019
Asia       1,968,668       2,128,653 1,916,812 2,110,761       2,064,848       1,950,977       1,926,160
World 11,746,196 11,293,852 9,813,355 9,362,117 10,040,656 10,508,491 10,208,812

All figures in tonnes

Global production of dried peas in 2010 was estimated at 10.2 million tonnes with Canada being the largest producer in the world at 2.9 million tonnes. A portion of peas are further processed into different components: proteins, fibres and starch. The separation of pea components can be based on a dry-milling or an aqueous separation process and the use of organic solvents is not required.

There is currently no publicly available data on the size of the global pea protein market. However, Burcon management believes that only a small fraction of the global production of dried peas is further processed into pea protein concentrates and pea protein isolates. Despite a small market for pea protein, the unique functionality of Burcon’s PEAZAZZpea protein could be a major factor in expanding and growing the vegetable protein market.

Canola Protein

The initial market for Nutrateincanola protein isolate is anticipated to be in the high-value animal feed sector. Nutrateincanola protein isolate is expected to be a nutritional and functional protein ingredient that offers a compelling alternative source of protein for animal and fish feed manufacturers. Nutrateinhas high nutritional and functional attributes that make it a suitable replacement for the costly whey protein concentrates in animal feed. The initial market for Puratein® canola protein isolate and Superteincanola protein isolate is anticipated to be food and nutrition processors that target: the baking industry; meat analogue manufacturers (e.g. veggie-burgers); beverage processors (non-dairy fortified drinks); sport nutrition manufacturers; and prepared foods manufacturers incorporating whole egg, dried egg white or certain dairy proteins.




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The overall strategic intent is to build Nuratein, Puratein® and Superteincanola protein isolates as global products through an alliance with a development partner. Burcon continues to work with food and beverage manufacturers and a leading animal feed company to establish the value of all three of Burcon’s canola proteins in potential market applications.

Intellectual Property

Patents

In October 1999, Burcon acquired the shares of Burcon-MB. At the time of the acquisition, Burcon-MB held patents and applications covering the protein micellar mass process for extracting and producing a canola protein isolate. Since the acquisition, Burcon has focused on developing its protein extraction and purification processes and seeking patent protection for its developments. Through Burcon-MB, Burcon has filed patent applications in various countries over its inventions. Burcon’s patent applications can be grouped into three categories:

  • applications to protect additional novel protein extraction and purification technologies;

  • applications to protect the uses of Puratein® , Superteinand Nutratein canola protein isolates, CLARISOYsoy protein, PEAZAZZpea protein, and other plant proteins, for example, as functional food and beverage ingredients; and

  • applications to protect the "signature characteristics" of Puratein®, Supertein and Nutrateincanola protein isolates, CLARISOYsoy protein, PEAZAZZ pea protein and other plant proteins.

As of the date of this AIF, Burcon’s patents and patent applications cover 53 distinct inventions. Burcon has filed applications for most of its inventions internationally under the Patent Cooperation Treaty of the World Intellectual Property Organization. As at the date of this AIF, Burcon holds 193 issued patents in various countries, covering a number of key processes and uses of Burcon’s products as functional food and beverage ingredients, 34 of which have been issued in the U.S. Burcon holds patents or has filed patent applications in: Australia, Brazil, Canada, China, Hong Kong, India, Japan, the European Union, Mexico, New Zealand, Russia, South Africa, South Korea and the United States. Burcon currently has over 375 patent applications that are being reviewed by the patent offices in various countries, 74 of which are U.S. patent applications.




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Granted U.S. Patents

Burcon holds 34 issued patents in the United States relating to canola protein isolate and flax protein isolate. These patents cover the protein micellar mass canola protein isolate technology acquired from Burcon-MB as well as improvements to the protein extraction and purification technologies made by Burcon. These new inventions include:

  • improving the quality of the input meal prior to the purification and extraction process, which results in better protein quality and higher protein yield. The residual oil from canola meal is traditionally recovered using a solvent called hexane. After the residual oil has been extracted, the hexane is recovered by heating the canola meal to a high temperature of about 110°C to 140°C. Burcon has been granted 2 U.S. patents covering a low-temperature process of recovering the hexane at temperatures below 100°C and below 50°C, respectively, to provide a desolventized meal that allows for improved protein recovery. Burcon also holds a U.S. patent to protect novel processing conditions in oil seed meal preparation and the production of a tailored meal in place of conventional canola meal. Through tailoring the input meal, including the low-temperature process, Burcon is able to produce canola protein isolates with superior organoleptic properties (improved colour, taste, aroma and mouth feel);

  • process improvements to produce canola protein isolate efficiently and to obtain higher yields of canola protein isolate;

  • processes for reducing phytic acid in the production of protein isolates from oilseed meals. Phytic acid is a naturally occurring anti-nutritional component found in oilseed meals such as canola meal and soybean meal;

  • protection covering important processing conditions for producing Superteincanola protein isolate as well as for the preparation of a highly refined Superteincanola protein isolate;

  • protection covering the composition of the dominant species of protein in Burcon’s Puratein® canola protein isolate. Puratein® is a cruciferin-rich canola protein isolate comprised principally of globulin proteins, allowing it to have unique functional qualities;

  • protection covering the process for producing Nutrateincanola protein isolate. Nutrateinis rich in both of the two major storage proteins found in canola: napin and cruciferin, making it a suitable ingredient for animal feed and aquaculture applications;




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  • processes to improve the final colour profile of Puratein® canola protein isolate and Superteincanola protein isolate;

  • applications for the uses of canola protein isolate as a functional food and beverage ingredient;

  • the use of canola protein isolate as a flavour enhancer in a food product;

  • alternative processes for producing canola protein isolates;

  • protection covering the process for producing protein isolates using mustard seed as a starting material; and

  • processes for the production of a flax protein isolate with unique protein profiles.

Patent Strategy

Burcon believes that it has developed a dynamic patent portfolio by aggressively seeking protection for new technologies as well as further protecting current technologies. In addition, Burcon has filed patent applications to cover alternative extraction technologies, which, in Burcon’s opinion, would not be commercially viable. Such filings have been made as part of Burcon’s defensive strategy to gain as much protection in the protein extraction and purification space as possible. Burcon will continue its research and development to further refine its processes and make new discoveries. The Company will continue to file additional patent applications to protect these discoveries.

Trade-marks

Burcon has obtained trade-mark registrations for "Puratein", and the slogan “A New World in Protein” in Canada and the United States. The Company has also filed for trade-mark protection for the brand names “Nutratein” and “PEAZAZZ” in Canada and the United States and "Supertein" in Canada. Burcon had previously obtained trademark registrations for “CLARISOY” in the United States and Canada. In June 2011, Burcon and ADM entered into a trademark assignment and license agreement pursuant to which Burcon assigned its ownership of the CLARISOYtrademark to ADM. In return, Burcon has obtained a worldwide, non-exclusive, royalty-free license to use the CLARISOYtrademark for corporate marketing and promotion of Burcon, conducting research or development of CLARISOYsoy protein products and compliance with the requirements of applicable law. Burcon also has the option to re-acquire the CLARISOYtrademark if the license under the License and Production Agreement is terminated.




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Facilities

Burcon’s head office is located at 1946 West Broadway, Vancouver, British Columbia, Canada in leased office space. Through Burcon-MB, Burcon leases the premises where the Winnipeg Technical Centre is located at market rental rates. These premises are located at 1388 Waller Avenue, Winnipeg, Manitoba, Canada. The lease will expire on August 31, 2014. At its option and subject to the conditions to be met by the landlord, Burcon may renew the lease for a further term of two years. The premises include a 10,333 square foot facility in a light industrial park. Burcon owns the equipment in this facility which includes tanks of up to 20,000 litre capacity, membrane systems, centrifuges, filter presses, various dryers and laboratory analytical equipment. Burcon operates exclusively and independently within these facilities under the immediate direction of its management. Certain services such as laboratory testing and analysis which cannot be conducted internally are contracted out as necessary.

Personnel

Burcon-MB currently has 15 employees and/or contractors with varying degrees of technical expertise who perform the duties relating to the operation of the research laboratory and pilot plant. Additionally, Burcon currently has 11 employees and/or contractors responsible for accounting, administration, corporate development, investor and public relations, legal and research and development activities.

Competitive Conditions

Burcon has licensed its soy protein technology to ADM and will support ADM’s efforts to commercialize CLARISOYsoy protein. Burcon is working on securing one or more strategic partners to commercialize its Puratein® canola protein isolate, Superteincanola protein isolate, Nutrateincanola protein isolate and PEAZAZZpea protein.

The protein ingredient market is a global industry dominated by a few relatively large participants. Burcon recognizes that the selective use of alliances and partnerships can lower certain risks and can be the fastest and most profitable approach to maximizing revenues and cash flow. Recognizing this, Burcon entered into the License and Production Agreement with ADM to commercialize Burcon’s soy protein ingredients. See "Material Contracts".

ADM is a public company with annual revenues at approximately US$81 billion (fiscal 2011). It is a major international company that produces among other things, ethanol, high fructose corn syrup, soy flour, soy protein concentrate, soy protein isolate and wheat gluten and is a world leader in oilseed crushing.




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Burcon recognizes that, in addition to ADM, there are other large industry participants with significant resources that dominate the plant protein ingredient industry. Two of the other major industry participants that sell plant protein ingredients to the food and beverage industries include Cargill Inc. ("Cargill") and Solae.

Cargill is the U.S.’s largest private company with annual revenues of US$119.5 billion (2011). Cargill is an international producer, marketer, processor and distributor of agricultural, food, financial and industrial products and is one of the world’s largest canola crushers. It produces soy flour, soy grits and textured soy protein.

Solae is a world leader in soy-based proteins and ingredients for the food, meat and nutritional products industries. Headquartered in St. Louis, Missouri, with annual revenue exceeding US$1 billion (2011), the company was formed through an alliance between Bunge Limited ((NYSE: BG) fiscal 2011 revenue: US$58.7 billion) and E.I. du Pont de Nemours and Company ("DuPont"), ((NYSE: DD) fiscal 2011 revenue: US$38.7 billion). In May 2012, DuPont acquired Bunge’s 28% stake to gain full ownership of Solae.

The pea protein industry is dominated by three major participants: Roquette, Cosucra Groupe Warcoing and Nutri-Pea Limited. Based in France, Roquette is a private company which produces more than 700 by-products from the starch extracted from corn, wheat, potatoes and peas. It has grown to become the second largest producer of starch in Europe and fifth largest producer in the world. Roquette is currently the largest participant in the pea protein industry.

Cosucra Groupe Warcoing is a Belgian group of independent companies dedicated to the development, production and promotion of natural ingredients from chicory and yellow pea. Cosucra’s line of products includes pea protein isolate, pea fibre, pea hull fibre and pea native starch.

Based in Manitoba, Canada, Nutri-Pea Limited is a privately owned company specializing in the manufacture of food ingredients derived from Canadian yellow peas. Nutri-Pea extracts fibre, starch and protein products from yellow peas.

Rising commodity prices have had a salient impact on the global aquaculture and livestock farming sectors in recent years, as they have had a direct impact on feed costs as well as on energy costs. These rising input prices have in turn been one of the factors that have increased the cost to produce animal proteins (egg protein products as well as the dairy proteins, casein and whey). Burcon anticipates that under commercial production levels, it will be able to produce its plant protein isolates at a cost level which will make them significantly competitive with animal proteins.




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Burcon offers a value proposition for both the multibillion-dollar oilseed crushing industry which produces enormous volumes of canola meal and soybean meal that currently sell as relatively low margin animal feed. Burcon has the technology and know-how to add value to these meals by extracting unique and potentially valuable food proteins. The unique nutritional and functional characteristics of Puratein® canola protein isolate, Superteincanola protein isolate, Nutrateincanola protein isolate, CLARISOYsoy protein and PEAZAZZpea protein differentiate them from the existing soy proteins as well as from the existing animal based proteins (casein, whey and egg). It is these unique attributes which Burcon anticipates will make the proteins valuable to the food and beverage industry.

For the branded product companies and the food ingredient companies, the value proposition comes from both the novel properties of Burcon’s proteins as well as the inherent first-mover advantage. Exclusivity through patent protection and the first-mover advantage could add significant value to Burcon’s opportunity in an industry where first-movers dominate, and market share changes slowly. For example, the iconic sport beverage brand Gatorade owned 83% of the sport beverage market in the United States in 2007, down only 10 percentage points from its 93% share which it enjoyed at its peak two decades earlier (source: Advertising Age magazine April 21, 2008). Taken together, the exclusivity and first-mover advantage could create an opportunity for food and beverage processors to brand or co-brand multiple new products fortified with Burcon’s proteins.

See also "Risk Factors".

Environmental Matters

Burcon’s extraction processes use no harsh chemicals and emit no noxious odours or significant waste products. Biodegradable and/or recyclable input materials, end-products and by-products are used and, therefore, are expected to present no significant environmental risk. As such, Burcon does not foresee any financial and operational effects of environmental protection or requirements on the capital expenditures, earnings and the competitive position of Burcon in the current financial year or in the foreseeable future.

Burcon’s processes as demonstrated to date are expected to work equally well on input materials from both genetically modified ("GM") and non-GM sources.

Regulatory Approval For Marketing CLARISOY

Food-grade soy protein isolate first became available on October 2, 1959 with the dedication of Central Soya's edible soy isolate, Promine D, production facility in Chicago. An edible soy isolate and edible spun soy fiber has also been available since 1960 from the Ralston Purina Company in St. Louis, where they had originally




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developed the technology. In 1987, Protein Technologies, Inc. ("PTI") became the world's leading maker of isolated soy protein and was subsequently acquired by DuPont.

Soy protein isolate is a highly refined or purified form of soy protein with a minimum protein content of 90% on a moisture-free basis. It is made from defatted soy flour which has had most of the non-protein components, fats and carbohydrates removed. Because of this, it has a neutral flavour and will cause less gas due to bacterial flatulence.

Soy protein isolates are mainly used to improve the texture of meat products, but are also used to increase protein content, enhance flavour, and as an emulsifier.

Pure soy protein isolate is used mainly by the food industry. It is sometimes available in health stores or in the pharmacy section of the supermarket. It is usually found combined with other food ingredients.

In 1995, the New England Journal of Medicine (Vol. 333, No. 5) published a report from the University of Kentucky entitled, "Meta-Analysis of the Effects of Soy Protein Intake on Serum Lipids." It was financed by the PTI division of DuPont, The Solae Company, St. Louis. This meta-analysis concluded that soy protein is correlated with significant decreases in serum cholesterol, Low Density Lipoprotein LDL (bad) cholesterol and triglyceride concentrations. However, High Density Lipoprotein HDL (good) cholesterol did not increase. Soy phytoestrogens (isoflavones: genistein and daidzein) adsorbed onto the soy protein were suggested as the agent reducing serum cholesterol levels. On the basis of this research, PTI, in 1998, filed a petition with FDA for a health claim that soy protein may reduce cholesterol and the risk of heart disease.

In October 1999, the FDA approved a health claim for soy protein and its role in reducing the risk of coronary heart disease. Food manufacturers may label foods containing soy protein by stating that "Diets low in saturated fat and cholesterol that include 25 grams of soy protein daily may reduce the risk of heart disease. One serving of (name of food) provides __ grams of soy protein." One serving (1 cup or 240 mL) of soy milk, for instance, contains 6 or 7 grams of soy protein.

While soy protein and soy protein isolates themselves have not been granted GRAS status by the FDA, they are widely used in food and nutritional applications including infant formula. As a result, Burcon does not anticipate any regulatory process for its CLARISOYsoy protein. However, there can be no assurance that the FDA will not require companies producing and selling soy protein isolates to meet additional regulatory requirements in the future.




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Regulatory Approval For Marketing PEAZAZZ

Peas were one of the earliest cultivated food crops and have a long history of safe consumption in human foods. They are widely accepted and consumed as a vegetable in our daily diets. Although pea protein is a relatively new vegetable-based protein ingredient, it is commercially available and used by the food industry.

Burcon is not aware of pea protein and pea protein isolates being granted GRAS status by the FDA for use in food and nutritional applications. However, peas have had a substantial history of consumption for food use by a significant number of consumers. Therefore, Burcon does not anticipate any regulatory process for its PEAZAZZpea protein. However, there can be no assurance that the FDA will not require companies producing and selling pea protein isolates to meet additional regulatory requirements in the future.

Obtaining Regulatory Approval For Marketing Puratein®, Superteinand Nutratein

Canola meal is currently used as a protein ingredient in dairy, beef, swine and poultry rations and is recognized for its consistent quality and value. Canola meal’s nutritional value, even in animal feed applications, is limited by the presence of a large amount of fiber and other anti-nutritional factors such as glucosinolates. Glucosinolates are the sulphur compounds that give mustard its sharp taste. Analysis of Puratein® canola protein isolate and Superteincanola protein isolate conducted by independent testing laboratories has indicated very low levels of glucosinolates. Puratein® and Superteincanola protein isolates have numerous potential applications, primarily as a food ingredient and as a personal care product ingredient. Burcon is initially pursuing animal and feed applications for Nutrateincanola protein isolate. Moreover, Nutrateinmay have potential applications as a food ingredient also. See "Description of the Business". In order to market Puratein® canola protein isolate and Superteincanola protein isolate as a food ingredient, approvals must be obtained from the applicable regulatory authorities in the countries currently targeted for commercialization. Initially, these countries are the United States, the countries comprising the European Union and Canada. In order to market Nutrateincanola protein isolate as a potential human food and/or animal feed ingredient, approvals must be obtained from the applicable regulatory authorities in the countries currently targeted for commercialization. Initially, the target markets are the United States and Canada.




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United States

Puratein® and Supertein™

During fiscal 2008, Burcon, in conjunction with ADM, pursued regulatory recognition for Puratein® canola protein isolate and Superteincanola protein isolate.

A substance may be "generally recognized as safe" or "GRAS" as a food ingredient based on two principles: it is a prior sanctioned substance, meaning that it has been used in food before 1958; or it is determined to be GRAS by scientific experts based on scientific procedures. Accordingly, because canola meal (and canola protein contained therein) does not have a history of safe use in human foods, the determination that Puratein® canola protein isolate and Superteincanola protein isolate are GRAS must be based on scientific procedures.

Scientific studies were conducted during fiscal 2008 and based on those studies, Burcon and ADM prepared a dossier of data that included scientific information about canola, how canola is grown, handled and processed, Burcon’s protein extraction process and finally, the intended uses of the proteins in foods and beverages. A panel of qualified experts in the fields of food safety, toxicology, nutritional sciences, food allergies and pediatric nutrition reviewed the dossier to which it also had input and affirmed unanimously that the proteins are safe for their intended uses. In October 2008, Burcon’s Puratein® canola protein isolate and Superteincanola protein isolate achieved self-affirmed GRAS status.

Substances that are GRAS under conditions of their intended use are exempted from the usual Federal Food, Drug, and Cosmetic Act ("FFDCA") food additive tolerance requirements.

For a substance to be GRAS, the scientific data and information about the use of the substance must be widely known and there is a consensus among qualified experts that the data and information establish that the substance is safe under the conditions of its intended use.

When a use of a substance does not qualify for the GRAS exemption, then the substance is considered to be a food additive under the FFDCA. Use of the substance is subject to the premarket approval mandated by the FFDCA. For a food additive, privately held data and information about the use of a substance are sent by the proponent to the FDA, which evaluates the data and information to determine whether the data and information establishes that the substance is safe under the conditions of its intended use. If found unsafe, the FDA may take enforcement action to stop distribution of the food substance and foods containing it on the grounds that such foods are or contain an unlawful food additive.




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A GRAS designation typically exists in one of three forms:

1.

Self-affirmed. The manufacturer of the substance has performed all necessary research, including the formation of an expert panel to review safety concerns, and is prepared to use these findings to defend its product's GRAS status.

2.

FDA-pending. The manufacturer has performed all the aforementioned due diligence, and submitted to the FDA for GRAS approval.

3.

No comment. The FDA has reviewed a product's GRAS notification claim and responded with "no comment"; i.e., no further challenges on the product's GRAS status.

To enhance consumer acceptance of Puratein® canola protein isolate and Superteincanola protein isolate, Burcon and ADM chose to pursue GRAS notification for Puratein® canola protein isolate and Superteincanola protein isolate. GRAS notification is a voluntary procedure whereby a company informs the FDA of its determination that the use of a substance is GRAS.

During fiscal 2010, Burcon’s scientists collaborated with ADM in the preparation and review of the manuscripts for the publication of the toxicology studies conducted in fiscal 2008 as part of the GRAS self-affirmation process. On August 20, 2009 and November 3, 2009, Burcon announced the publication of the Puratein® and Superteintoxicology studies, respectively, in peer-reviewed journals. The publication of these scientific studies forms a significant part of the GRAS notification process.

On January 19, 2010, Burcon announced that it had filed a formal notification in accordance with the FDA proposed regulation 62FR 18938, having determined, based on a review of the data referenced in the notification, that Burcon’s Puratein® canola protein isolate and Superteincanola protein isolate are GRAS for their intended use as an ingredient in a variety of food and beverage applications and in addition, that both substances are exempt from premarket approval requirements of the Food, Drug and Cosmetic Act (the “GRAS Notification”). In response to comments from the FDA, Burcon modified and resubmitted the GRAS Notification in February 2010. In a letter dated April 1, 2010, the FDA formally acknowledged receipt of the GRAS Notification.

After the FDA acknowledges receipt of the GRAS notice, it then evaluates whether the submitted notice provides a sufficient basis for the GRAS determination and whether information in the notice or otherwise available to the FDA, raises




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issues that lead the FDA to question whether use of the substance is GRAS. Following the evaluation and within 180 days, the FDA responds in one of 3 ways:

1.

the FDA does not question the basis for the notifier's GRAS determination;

2.

the FDA concludes that the notice does not provide a sufficient basis for a GRAS determination (for example, the notice does not include appropriate data and information, or because the available data and information raise questions about safety of the notified substance); or

3.

the FDA has, at the notifier's request, ceased to evaluate the GRAS notice.

A substance is GRAS notified when, after reviewing the GRAS notification, the FDA responds with a no-objection letter if it is satisfied with the submission.

On August 30, 2010, Burcon announced that the U.S. Food and Drug Administration issued a no objection letter with respect to Puratein® and Superteincanola protein isolates. This response indicates that the FDA has no objection to the conclusion that Puratein® and Superteinare Generally Recognized as Safe (GRAS) among qualified experts for use alone or together as an ingredient in dairy products, grain products, fruit and vegetable juices and beverages, salad dressings, meal replacements and nutritional bars.

Nutratein

Human Food

Burcon’s Nutrateincanola protein extraction process allows for the production of a canola protein that is rich in both of the two major storage proteins found in canola: napin and cruciferin. Nutrateinis a blended canola protein isolate that consists of the napin-rich protein fraction (Supertein) and the cruciferin-rich protein fraction (Puratein®) of canola.

The FDA has issued a no objection letter with respect to Puratein® and Superteincanola protein isolates. This response indicates that the FDA has no objection to the conclusion that Puratein® and Superteinare GRAS for their intended uses in human food.

Burcon management believes that a substantial equivalence claim, based on the similarities to Puratein® and Superteincanola protein isolates, can be made in regard to Nutrateincanola protein isolate being Generally Recognized as Safe (GRAS) for its intended uses in human food applications. In order to obtain a substantial equivalence claim, Burcon is required to submit to the FDA a summary




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of its scientific and regulatory assessment of the food in the form of a New Protein Consultation (NPC) document. The summary will include information regarding Nutrateinsuch as protein characterization, compositional analysis, protein uses and levels of intake and the applicant’s conclusion on the safety and nutritional assessment of the protein.

Following the submission, the FDA responds to the applicant by letter indicating one of the following:

1.     

the FDA does not question the basis for the applicant’s determination that the product is not materially different in any respect relevant to food safety from other canola protein isolate varieties;

2.     

the FDA requires additional information on this protein product in order to determine a safety conclusion; or

3.     

the FDA has, at the applicant’s request, ceased to evaluate the NPC.

Animal Feed

Nutrateincanola protein isolate is a nutritional and functional protein ingredient that offers a compelling alternative source of protein for animal feed manufacturers. Animal feed, and in particular, high-valued feed replacers are currently dominated by the use of high-cost whey protein concentrates (“WPC”). Burcon’s Nutrateincanola protein isolate has the nutritional value that could compete with WPC.

Although Nutrateincanola protein isolate is extracted from canola meal which is currently being used as a protein ingredient in livestock feed, regulatory approvals for Nutrateinas a novel feed ingredient will still be required.

The regulatory approval process in the United States for Nutrateincanola protein isolate as an animal feed ingredient requires a submission of a GRAS Notification to the FDA’s Center for Veterinary Medicine (“CVM”), Division of Animal Feeds, indicating scientific evidence of Nutratein’s safe and intended uses in animal feed. The regulatory process is similar to the GRAS Notification process for Burcon’s Puratein® and Superteincanola protein isolates. A substance is GRAS notified when, after reviewing the GRAS notification, the FDA responds with a no-objection letter if it is satisfied with the submission.

The CVM regulates the manufacture and distribution of food additives and drugs that will be given to animals. These include animals from which human foods are derived, as well as food additives and drugs for pet (or companion) animals.




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Europe

Puratein® and Supertein

Where a new ingredient has not been used to a significant degree in human food in the EU market prior to May 1997, the ingredient is regarded as a novel food ingredient and would be regulated under the 1997 Regulation (EC) No 258/97 concerning Novel Foods and Novel Food Ingredients.

Food supplement products are marketed in Europe as foodstuffs or medicines depending on the indication of the product. A "foodstuff" is defined as any substance or product, whether processed, partially processed or unprocessed, intended to be ingested by humans. The use of Puratein® canola protein isolate and Superteincanola protein isolate in pill or powder form for use in supplement type products (e.g. energy bars and drinks) would categorize the ingredients as a foodstuff in Europe, provided that no health related claims were declared.

According to the EU novel food regulations, a novel food application must contain a general description of the novel food, including technical data and categorization. The application should outline the rationale justifying that Puratein® canola protein isolate and Superteincanola protein isolate is in fact "novel" as prescribed under the regulations. The EU has formulated a Scientific Committee for Food which evaluates various classes and subclasses of novel foods. Puratein® canola protein isolate and Superteincanola protein isolate fall under two subclasses depending on whether it was obtained from genetically or non-genetically modified canola meal.

The European Commission published its proposal regulation that will replace the current novel food regulation. No date has been given as to when this will come into force. The new regulation would require applicants to submit a novel food application directly to the European Food Safety Agency (“EFSA”) who will do the necessary evaluation and scientific assessment. Following a no-objection response from the EFSA, the novel food ingredient can be marketed in all EU countries. Burcon will therefore be required to meet all requirements prescribed under the EU’s novel foods regulation for marketing Puratein® canola protein isolate and Superteincanola protein isolate.

Canada

Puratein®, Supertein& Nutratein

The manufacture and sale of Puratein®, Superteinand Nutrateincanola protein isolates is subject to compliance with regulatory regimes in Canada that require a manufacturer to demonstrate a product’s safety as a food.




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These activities are governed by the federal Food and Drugs Act and Regulations, which are administered by the Food Directorate, Health Products and Food Branch of Health Canada, a Canadian government agency. The Food and Drug Regulations require a manufacturer to notify the Food Directorate in writing of its intention to sell or advertise for sale of a novel food.

In Canada, each of Puratein®, Superteinand Nutrateincanola protein isolate is considered a “novel food”, meaning a food that does not have a history of safe use in humans or that has been manufactured by a process that has not been previously applied to it and which causes it to undergo a major change.

The regulatory pathway to product acceptance requires a submission of a Safety Assessment Data Package to Health Canada that includes details such as novel extraction process, nutritional, toxicology and allergenicity considerations. The package must also include specific information on the novel food’s intended use and directions for its preparation, as well as the text of all labels to be used in connection with the novel food.

The steps toward obtaining approval as a novel food include the following:

  • preliminary consultation and meetings with Health Canada officials to review the characteristics and make-up of the product and obtain guidance on the Safety Assessment Data Package;

  • toxicology tests conducted by recognized research and testing facilities to provide evidence of the safety of the product; and

  • submission to Health Canada Food Directorate of a Novel Food Notification that includes a description of the product, its development and intended uses; details of the procedures for manufacturing; packaging and storing the product; information regarded expected levels of consumption; and results of the toxicology tests;

  • safety assessment of the novel food by the relevant bureau of the Food Directorate and presented to the Food Rulings Committee for consideration; and

  • Health Canada issues a no objection letter to the sale of novel food product as human food in Canada as specified in the notification.

Review of the Novel Food Notification by Health Canada will determine whether the toxicology test information is sufficient to establish safety of the product or whether any additional testing is required. During fiscal 2011, Burcon investigated the process for approval of Puratein® canola protein isolate and Superteincanola protein isolate as novel foods in Canada. Until Burcon has




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secured a strategic partner for Puratein®, Superteinand Nutratein, Burcon does not intend to pursue regulatory approval as a food for these canola proteins in Canada. However, there is no assurance that Health Canada will approve the product or will not require further testing.

Nutratein

Animal Feed

In accordance with the federal Feeds Act and Regulations, an application for a novel feed ingredient such as Nutrateincanola protein isolate is submitted to the Canadian Food Inspection Agency (“CFIA”), Animal Feed Division which approves feed ingredients and registers feed products in order to verify that feeds meet:

  • standards for safety and usefulness, and

  • regulatory requirements for labelling, prior to importation, manufacture or being offered for sale to livestock producers and other customers.

The safety and efficacy evaluations are conducted by staff of the Animal Feed Division. The review of a submission to register a novel feed or ingredient involves a complete assessment of product safety (to livestock, workers, food and the environment), a review of data supporting the intended purpose of the product, an assessment of the product's compliance with regulatory standards and a review of the label for compliance with the Feeds Regulations.

Estimated Timelines

Obtaining "novel food" status in Europe and Canada for Puratein® and Superteincould take between 1 1/2 and 2 1/2 years. The entire process for obtaining a GRAS substantially equivalent status for Nutrateincanola protein isolate in the United States – from submission to receiving a no objection letter –could take between one to two years. These estimates are based on the assumption that there are no major issues raised by the applicable regulatory authorities. See "Risk Factors". Burcon’s Superteinand Puratein® canola protein isolates have now been GRAS-notified in the United States. Burcon has determined that it will postpone the process for pursuing regulatory approval of Puratein® and Superteinin Canada and Europe and Nutrateinin the United States and Canada until Burcon has secured a strategic partner for these products and the terms of a strategic alliance have been determined with a strategic partner.




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Risk Factors

Patents and Proprietary Rights

Burcon’s success will depend, in part, on its ability to obtain patents, maintain trade secret protection and operate without infringing on the proprietary rights of others or having others infringe on its rights. Burcon has filed applications for most of its inventions internationally under the Patent Cooperation Treaty of the World Intellectual Property Organization. As at the date of this AIF, Burcon has been granted a total of 193 patents in various countries covering a number of key processes for producing canola and flax proteins and uses of Burcon’s canola and flax protein products as functional food and beverage ingredients. Of those patents, 34 have been granted in the United States. Countries in which Burcon holds issued patents or has filed patent applications are: Australia, Brazil, Canada, China, Hong Kong, India, Japan, the European Union, Mexico, New Zealand, Russia, South Africa, South Korea and the United States. Currently, Burcon has over 375 patent applications that are being reviewed by the patent offices in those countries.

The patent positions of food processing and manufacturing businesses, including Burcon’s, are uncertain and involve complex legal and factual questions for which important legal issues are largely unresolved. For example, the coverage claimed in a patent application can be significantly reduced before a patent is issued. There can be no assurance that any of Burcon’s patent applications will result in the issuance of patents, that Burcon will develop additional proprietary products that are patentable, that any patents issued to Burcon will provide it with adequate protection or any competitive advantages, that such patents will not be successfully challenged by any third parties or that the patents of others will not impede Burcon’s ability to commercialize its technology. Furthermore, there can be no assurance that others will not independently develop products or technologies similar to Burcon’s or, if patents are issued to Burcon, design around any patented products developed by Burcon.

Publication of discoveries in the scientific or patent literature often lag behind actual discoveries. As a consequence, Burcon cannot be certain that it was the first creator of inventions covered by issued patents or pending patent applications or that it was the first to file patent applications for such inventions. Moreover, Burcon might have to participate in interference proceedings declared by the United States Patent and Trademark Office or other proceedings outside the United States, including oppositions, to determine priority of invention or patentability. An unfavourable outcome in an interference or opposition proceeding could preclude Burcon from selling products using the technology or require Burcon to obtain license rights from prevailing third parties. There is no guarantee that any prevailing party would offer Burcon a license or that Burcon could acquire any license made available to it on commercially acceptable terms. There can be no




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assurance that the patents that Burcon has received or may be able to obtain in the future would be held valid or enforceable by a court or that a competitor’s technology or product would be found to infringe such patents.

Part of Burcon’s intellectual property is in the form of trade secrets and know-how and may not be protected by patents. There can be no assurance that Burcon will be able to protect its trade secrets. To help protect Burcon’s rights, Burcon requires its employees, consultants, advisors and collaborators to enter into confidentiality agreements. There can be no assurance that these agreements will provide meaningful protection for Burcon’s trade secrets, know-how or other proprietary information in the event of any unauthorized use or disclosure.

Protection of Intellectual Property is Expensive

Burcon’s future success and competitive position depends in part on its ability to obtain and maintain certain proprietary intellectual property rights used in its principal product candidates. Any such success may be achieved in part by prosecuting claims against others who it believes are infringing its rights and by defending claims of intellectual property infringement brought by its competitors and others. Burcon’s involvement in any such intellectual property litigation could result in significant expense incurred by Burcon, adversely affecting the development of product candidates or sales of such challenged product or intellectual property and diversion of efforts of Burcon’s technical and management personnel, whether or not such litigation is resolved in Burcon’s favour. Some of Burcon’s competitors may be able to sustain the costs of complex patent litigation more effectively than Burcon because they have substantially greater resources. Uncertainties resulting from the initiation and continuation of any litigation could have a material adverse effect on Burcon’s ability to continue its operations. In the event of an adverse outcome as a defendant in any such litigation, Burcon may, among other things, be required to:

  • pay substantial damages;

  • cease the development, manufacture, use or sale of product candidates or products that infringe upon the intellectual property of others;

  • expend significant resources to design around a patent or to develop or acquire non-infringing intellectual property;

  • discontinue processes incorporating infringing technology; or

  • obtain licenses to the infringing intellectual property.

No assurance can be provided that Burcon would be successful in such development or in the acquisition of non-infringing technology or that such licenses




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for such infringing technology would be available upon reasonable terms, if at all. Any such development, acquisition or license could require the expenditure of substantial time and other resources and could have a material adverse effect on Burcon’s business and financial results. If Burcon does not obtain such licenses, it could encounter delays in the introduction of products or could find that the development, manufacture or sale of products requiring such licenses could be prohibited.

Should third parties file patent applications, or be issued patents claiming technology also claimed by Burcon in pending applications, Burcon may be required to participate in interference proceedings with the United States Patent and Trademark Office, or other proceedings outside the United States, including oppositions, to determine priority of invention or patentability, which could result in substantial cost to Burcon even if the eventual outcome were favourable to Burcon.

Early Stage of Development

Burcon is at an early stage of development. On June 18, 2012, Burcon announced that ADM has begun commercial production of CLARISOYsoy protein. However, it has not commercialized any of its other products, and accordingly, has not begun to market or generate significant revenues from the commercialization of these products. There can be no assurance that any of its products will: meet applicable food regulatory standards; obtain required regulatory approvals in countries where such approvals have yet to be sought; be capable of being produced in commercial quantities at reasonable costs; or be successfully marketed; or that the investment made in such potential products will be recouped through sales or related royalties. With the exception of CLARISOYsoy protein, none of Burcon’s potential products are commercially available as a food ingredient for human consumption. Given that ADM has chosen not to license Burcon’s technology for producing Puratein® canola protein isolate and Superteincanola protein isolate, Burcon must secure an alternative strategic partner to do so. If Burcon is unable to secure an alternative strategic partner for its canola protein isolates then the commercialization of its products may be delayed or unsuccessful. Although Burcon is in discussions with potential partners for PEAZAZZpea protein and Nutrateincanola protein isolate, no strategic alliance has yet been formed. Even if Burcon commercializes a product or products, its business strategy may not be successful.

Burcon May Never Achieve Profitability

Burcon has accumulated net losses of approximately $52.9 million from its date of incorporation through March 31, 2012. Although Burcon expects to receive royalty payments from ADM pursuant to the License and Production Agreement,




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the magnitude of these royalty payments cannot be ascertained at this time. In the absence of a definitive time for when sales of products will occur, Burcon expects its accumulated net losses will increase as it continues to commercialize its products, its research and development and its product application trials. Burcon expects to continue to incur substantial losses for the foreseeable future. Burcon cannot predict if it will ever achieve profitability and, if it does, it may not be able to sustain or increase its profitability.

Burcon’s ability to achieve and maintain profitability will depend on, among other things, the market's acceptance of any of its products that receive regulatory approval. The commercial success of any of Burcon’s products will depend on whether:

  • they receive public and industry acceptance as a food ingredient and dietary supplement; and

  • they may be sold at competitive prices or are able to obtain sufficient royalty revenue from licensing which adequately exceeds Burcon’s production (or business) costs.

Market Conditions

Although Burcon has sufficient funds to operate until May 2013, it will need to raise capital in the near future through an equity offering in order to meet its business objectives. Although global financial markets have been in recovery, the inherent risk in investing in early stage companies such as Burcon may make it difficult for the Company to obtain capital and financing for its operations. There can be no assurance that additional financing may be available on acceptable terms, if at all.

Financing Requirements

Since acquiring Burcon-MB on October 8, 1999, Burcon has raised gross proceeds of approximately $49.1 million from the sale or issuance of equity securities. Developing Burcon’s products and conducting product application trials is capital intensive. As at the March 31, 2012 balance sheet date, Burcon had $6.2 million in cash and cash equivalents and short term investments which, management estimates, are sufficient resources to continue the current level of operations for less than a year. Therefore, Burcon will need to raise additional capital to:

  • fund operations;

  • fund product application trials;




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  • continue research and development for commercial production of its products;

  • commercialize its products; and

  • generate data to support regulatory approvals in Canada, the European Union and the United States, where necessary.

Additional financing may not be available on acceptable terms, if at all. If Burcon raises funds by issuing more equity securities, holders of common shares will experience dilution. If Burcon is unable to raise additional funds when it needs them, it may be required to delay, reduce or eliminate some or all of its development programs and some or all of its product application trials. Burcon may also be forced to license technologies to others that it would prefer to develop internally.

Product and Market Related Risks

The long-term success of Puratein®, Superteinand Nutrateincanola protein isolates, CLARISOYsoy protein and PEAZAZZpea protein hinges upon market acceptance by food and feed ingredient manufacturers and suppliers in numerous product applications. Burcon has not yet secured a strategic partner for its technology for producing Puratein®, Superteinand Nutrateincanola protein isolates or PEAZAZZpea protein. If Burcon is unable to secure a strategic partner to assist in establishing credibility, market acceptance of and the commercialization of its products may be delayed or unsuccessful. The commercial products manufactured by Burcon must exhibit certain functional and nutritional characteristics to garner any market share in the industries that are targeted. There can be no assurance that Burcon’s products will meet industry standards. Even though Puratein® , Superteinand Nutrateincanola protein isolates, CLARISOYsoy protein and PEAZAZZpea protein may be found to be functionally acceptable in product applications, there is no assurance that they will obtain market acceptance and within a reasonable time frame. Burcon’s products have only been produced in small scale batches, and the majority of food or feed ingredient manufacturers will require a substantial testing phase and demonstration of consistent delivery and production capabilities for commercialization. Without this capability, market acceptance of Puratein® , Supertein, and Nutrateincanola protein isolates, CLARISOYsoy protein and PEAZAZZpea protein may be delayed.

There are many large companies in the marketplace that manufacture and produce mature and well-known protein ingredients that have been used for many years. These companies also possess far greater financial, marketing and human resources than Burcon. Products such as dried egg white and soy protein isolate have been used in the food processing industry for years with successful results.




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These protein ingredients are proven to be functional, technologically sound, readily available and reliable. Burcon recognizes that it must devote resources and energy over a long period of time to develop these markets as they tend to be quite conservative. Food companies rely on taste, appearance and health appeal to sell their products and they are unlikely to accept even a lower priced product without comparable or superior functionality. Major companies in the food processing industry have invested hundreds of millions of dollars in brand and product development and will avoid ingredients or processes that may be of questionable or unproven benefit.

Consumer Acceptance

There is a continuing public issue regarding food products derived from genetically modified organisms ("GMOs"). Genetic modification, where a plant’s genetic makeup is altered by insertion, deletion or reversal of genes, often from an entirely different organism, should not be confused with traditional plant breeding techniques which have been used for generations to selectively breed plants with desirable traits. In fact, canola is a variation of rapeseed developed by Canadian plant breeders using traditional techniques.

The GMO debate centres on the issue of whether food products derived from GMOs pose potential health risks to consumers and/or the environment. Burcon’s processes for extracting a protein isolate from canola meal and soy are equally effective with starting materials from either GM or non-GM sources and can also utilize oilseed meals other than canola or soy. Therefore, if Burcon chooses to use starting materials from a GMO source, the resultant protein isolate may be less acceptable to some consumers.

Government Regulatory Approval

The approval, manufacture and sale of food ingredients, such as Burcon’s products, are governed by regulatory regimes in Canada, the United States and Europe that require a manufacturer to be able to demonstrate a product’s safety. In order to obtain approval to market a product, a manufacturer may be required to undertake controlled research and testing, which will be subject to government review and approval. There is a risk that government approval may not be received in a timely fashion or at all. See “Obtaining Regulatory Approval for Marketing Puratein®, Superteinand Nutratein”.

Rapid Technological Change

The food processing industry is subject to rapid and substantial technological change. There can be no assurance that developments by others will not render




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Burcon’s products or technology non-competitive or that Burcon will be able to keep pace with technological developments.

Significant Competition

Technological competition among food industry participants is intense and is expected to increase. Many competitors and potential competitors of Burcon have substantially greater product development capabilities and financial, scientific, marketing, and human resources than Burcon. Other companies may succeed in developing products earlier than Burcon, obtaining regulatory approvals for such products more rapidly than Burcon or in developing products that are more effective than those proposed to be developed by Burcon. While Burcon will seek to expand its technological capabilities in order to remain competitive, there can be no assurance that research and development by others will not render Burcon’s technology or products obsolete or non-competitive.

Lack of Commercial Manufacturing Experience

Burcon has not yet manufactured any products in substantial quantity. To be successful, Burcon’s products must be manufactured in commercial quantities in compliance with regulatory requirements and at acceptable cost. In order to manufacture its products in commercial quantities, if it elects to do so, Burcon will need to develop its own manufacturing facilities or contract with third parties to manufacture its products. Developing its own commercial scale manufacturing facilities will require Burcon to raise substantial funds and to retain additional management and technical personnel who have manufacturing experience. No assurance can be given that Burcon will be able to make the transition to commercial production.

Ability to Hire and Retain Key Personnel

Burcon is highly dependent on its senior management and scientific and technical personnel. The competition for qualified personnel in the food industry is intense, and Burcon relies heavily on its ability to attract and retain qualified managerial, scientific and technical personnel. In addition, Burcon’s ability to manage growth effectively will require it to continue to implement and improve its management systems and to recruit and train new employees. There can be no assurance that Burcon will be able to attract and retain skilled and experienced personnel.

Reliance on Key Personnel

Burcon is dependent on certain members of its management and the loss of the services of one or more of these individuals could adversely affect the Company.




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Neither Burcon nor Burcon-MB has purchased key man insurance on behalf of any member of Burcon’s and/or Burcon-MB’s senior management.

Product Liability

Food products involve an inherent risk of product liability claims and associated adverse publicity. There can be no assurance that Burcon will be able to obtain or maintain product liability insurance on acceptable terms or with adequate coverage against potential liabilities. Such insurance is expensive and may not be available in the future on acceptable terms, or at all. The inability to obtain sufficient insurance coverage on reasonable terms or to otherwise protect against potential product liability claims could prevent or inhibit the commercialization of Burcon’s potential products.

DIVIDEND RECORD AND POLICY

There are no restrictions that could prevent Burcon from paying dividends provided that Burcon has retained earnings from which such dividends can be paid. Burcon has not declared any dividends on its Common Shares. The Company’s directors have determined that dividends will not be paid until a number of years after it has commenced commercial production of its products, and will only be paid if the directors believe that to do so would be in the best interests of the Company and its shareholders.

DESCRIPTION OF CAPITAL STRUCTURE

The authorized share capital of Burcon consists of an unlimited number of Common Shares without par value. Each holder of Common Shares is entitled to one vote in respect of each Common Share held by such holder at meetings of shareholders. In the event of the liquidation, dissolution or winding-up of the Company, whether voluntary or involuntary or any other distribution of its assets among its shareholders, the holders of Common shares will be entitled to receive the remaining property or assets of the Company available for distribution pro rata, in proportion to the number of Common Shares held. As at June 25, 2012, 30,001,008 Common Shares were issued and outstanding. In addition, the Company has 1,987,920 outstanding incentive options to purchase Common Shares.

MARKET FOR SECURITIES

The Common Shares have been listed and trade on the Toronto Stock Exchange ("TSX") under the symbol "BU" since June 18, 2009 and NASDAQ since October 27, 2011. Prior to their listing on the TSX, the Common Shares were listed and traded on the TSX Venture Exchange under the symbol “BU”. The following table sets forth, for the periods indicated, the reported high and low prices and total volume of trading of the Common Shares on the TSX:




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Calendar Period High Low Total Volume
April 2011 $10.40 $9.06 284,747
May 2011 $9.69 $8.55 380,141
June 2011 $9.27 $7.64 233,163
July 2011 $9.42 $7.35 319,070
August 2011 $8.62 $6.72 354,040
September 2011 $7.69 $6.00 382,860
October 2011 $8.00 $5.61 511,481
November 2011 $8.50 $7.60 601,416
December 2011 $8.21 $6.98 296,258
January 2012 $7.23 $6.28 240,442
February 2012 $7.64 $5.66 504,237
March 2012 $7.80 $6.12 452,156

During the fiscal year ended March 31, 2012, the Company granted options to directors to purchase up to 200,000 Common Shares. These options were granted on September 22, 2011 and November 16, 2011 at an exercise price of $6.78 per share and $8.05 per share, respectively.

DIRECTORS AND OFFICERS

Directors and Officers

The following chart sets out the name, province or state and country of residence of each director and officer of the Company, each such person’s principal occupation during the past five years, the period of time each has served as a director or officer of the Company and the Common Shares beneficially owned or controlled by each of them as at the date of this AIF. A biography of each director and officer, which includes a five year history of employment, follows under "Biographies of Directors and Officers". The term of office of each director will expire at the conclusion of the Company’s next annual meeting.




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Name, Position
and Municipality
of Residence
Principal Occupation
During the Previous
Five Years
Period as a
Director of
the Company
Common
Shares
Held
Options
Held
Allan Yap,
Chairman of the Board, Chief Executive Officer and Director,
Hong Kong, China
Chairman and Chief Executive Officer of Burcon; President of Burcon Group Limited (investment company) until July 2007 Since November 3, 1998 1,333,666 205,000
Johann F. Tergesen,
President, Chief Operating Officer and Director,
British Columbia, Canada
President and Chief Operating Officer of Burcon Since November 3, 1998 265,902 270,000
Rosanna Chau,
Director,
Hong Kong, China
Deputy Chairman and Managing Director of ITC Corporation Limited (investment holding) Since November 3, 1998 385,389 72,500
Paul Westdal,
Director,
Manitoba, Canada
President, Agri-Tec International Inc. (grain handling, storage and processing); Private Consultant; professional agrologist and member of Agricultural Institute of Canada Since October  8, 1999 566,971* 72,500

_______

*398,467 of these Shares are held by Pelican Pouch Inc., a company controlled by Paul Westdal.




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Name, Position
and Municipality
of Residence
Principal Occupation
During the Previous
Five Years
Period as a
Director of
the Company
Common
Shares
Held
Options
Held
Lawrence Wang,
Director,
Alberta, Canada
Professor Emeritus in the Department of Biological Sciences, University of Alberta since 2005; President and CEO, L&R Wang Enterprises Ltd. (sports/nutrition products); President and CEO, Canadian Cold Buster Ltd. (sports/nutrition products) Since September 3, 2009 67,700# 80,000
David Lorne John Tyrrell,
Director,
Alberta, Canada
Director, Li Ka Shing Institute of Virology, University of Alberta since April 2010; Canadian Institute of Health Research /Glaxo SmithKline Chair in Virology, Department of Medical Microbiology and Immunology, University of Alberta since 2004; Chief Scientific Officer of KMT (biotechnology company in Edmonton) since 2004; Director, Glaxo Heritage Research Institute, University of Alberta since 1992; Since December 1, 2009 4,600 60,000

 

_______

 

#30,100 of these Shares are held by Canadian Cold Buster Ltd., a company controlled by Lawrence and Rosa Wang.





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Name, Position
and Municipality
of Residence
Principal Occupation
During the Previous
Five Years
Period as a
Director of
the Company
Common
Shares
Held
Options
Held
  Professor of Medicine, Biochemistry and Medical Microbiology & Immunology, University of Alberta since 1982 & Chief Executive Officer, ViRexx Medical Corp. (Edmonton, Alberta based biotechnology company) from 2005 - 2007      
Alan Chan,
Director,
Hong Kong, China
Executive director of ITC Properties Group Ltd. (property development and investment) since March 2010 and ITC Corporation Limited (investing holding) since March 2009; Alternate (non-executive) director to Dr. Chan Kwok Keung, Charles of PYI Corporation Limited since July 2010; Executive director of PYI Corporation Limited since November 2011; financial analyst of Goldman Sachs (Asia) L.L.C. in Hong Kong from July 2006 to January 2009 Since April 20, 2010 NIL 85,000

 




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Name, Position
and Municipality
of Residence
Principal Occupation
Du
ring the Previous
Five Years
Period as a
Director of
the Company
Common
Shares
Held
Options
Held
Matthew Hall,
Directors,
British Columbia, Canada
Executive in Residence and member of Advisory Board, University of Victoria Peter B. Gustavson School of Business since May 2011; Associate, Goodbrand (Management Consultancy) since May 2011; Principal Consultant, Marketing, Communications and Sales at Matt Hall and Associates since April 2010; Managing Director/CEO, Food, Coffee and Beverages Division, Nestle U.K. from January 2008 to March 2010; Senior Vice President, Global Marketing, Communications and Sales, Vevey Switzerland at Nestle S.A. from April 2004 to December 2007 Since July 12, 2011 NIL 60,000
J. Douglas Gilpin,
Director,
Alberta, Canada
Consultant, providing corporate governance, corporate director and
business advisory services
Since September 1, 2011 NIL 40,000

 




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Name, Position
and Municipality
of Residence
Principal Occupation
During the Previous
Five Years
Period as a
Director of
the Company
Common
Shares
Held
Options
Held
Bradford Allen,
Director,
California, United States of America
Consultant, providing investment and business strategy advisory services Since June 21,
2012
NIL NIL
Jade Cheng,
Chief Financial Officer and Treasurer,
British Columbia, Canada
Chief Financial Officer and Treasurer of Burcon; Controller of Burcon Group Limited (investment company); Director and President of Burcon Group Limited since July 2007 n/a 179,412 192,500

Randy Willardsen,
Senior Vice-President, Process,
California, United States of America

Senior Vice-President, Process of Burcon; President, Willardsen Consulting & Engineering, Inc. (agriculture and biotech industries consulting services) n/a 341,900 140,000

Dorothy Law,
Senior Vice-President, Legal, Corporate Secretary,
British Columbia, Canada

Senior Vice-President, Legal of Burcon since September 2009; Vice-President, Legal of Burcon from September 2000 to September 2009; Corporate Secretary of Burcon; Director, Secretary and Corporate Counsel of Burcon Group Limited (investment company) From December 1998 to April 2010 240,907 192,500

 




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Name, Position
and Municipality
of Residence
Principal Occupation
During the Previous
Five Years
Period as a
Director of
the Company

Common
Shares
Held

Options
Held
Martin Schweizer,
Vice-President, Technical Development,
Manitoba, Canada
Vice President, Technical Development of Burcon since September 2009; Manager, Technical Development of Burcon NutraScience (MB) Corp. from January 2003 to September 2009 n/a 69,430 130,000
TOTAL SECURITIES     3,455,877 1,600,000

Committees

Burcon does not have an executive committee of its directors. Burcon has an audit committee, a corporate governance committee and a nominating and compensation committee. The members of the audit committee consist of J. Douglas Gilpin, Lorne Tyrrell and Lawrence Wang. The members of the corporate governance committee consist of J. Douglas Gilpin, Matthew Hall, Lorne Tyrrell and Paul Westdal. The members of the nominating and compensation committee consist of J. Douglas Gilpin, Matthew Hall, Lawrence Wang and Paul Westdal. Dr. Lawrence Wang resigned from his membership on Burcon’s nominating and compensation committee effective April 19, 2012.

Aggregate Ownership of Securities

As at the date of this AIF, directors and officers of Burcon as a group, beneficially owned, directly or indirectly, 3,455,877 or 11.5% of the issued and outstanding Common Shares of the Company. Directors and officers of Burcon and its subsidiaries held options to acquire an additional 1,600,000 Shares.

Biographies of Directors and Officers

Allan Yap – Director, Chairman and Chief Executive Officer

Dr. Yap has over 29 years of experience in finance, investment and banking. Dr. Yap was the President and a director of Burcon Group Limited from June 1998 to July 2007, a private company which is involved in real estate and other investments.




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Dr. Yap obtained his Honorary Doctor of Laws degree from the University of Victoria in 2001. Dr. Yap is the Chairman of Hanny Holdings Limited and executive director of Rosedale Hotel Holdings Limited (until May 2011) and See Corporation Limited (until June 2011), all of which are companies whose shares are listed on The Stock Exchange of Hong Kong Stock Limited. He is the chairman and chief executive officer of China Enterprises Limited, a company whose shares are traded on the OTC Securities Market in the United States. He is the executive chairman of Hanwell Holdings Limited (formerly PSC Corporation Ltd.), Intraco Limited and Tat Seng Packaging Group Ltd., all of which are companies whose shares are listed on the Singapore Exchange Limited. In June 2011, Dr. Yap was appointed as alternate director to Dr. Charles Chan of Television Broadcasts Limited, a company whose shares are listed on The Stock Exchange of Hong Kong Limited.

Johann F. Tergesen – Director, President and Chief Operating Officer

Mr. Tergesen was one of the founding shareholders of Burcon Capital Corp., which acquired B.M.W. Canola Inc. in October of 1999 and subsequently changed its name to Burcon NutraScience Corporation. Prior to his role as president and C.O.O. of Burcon NutraScience Corporation, Mr. Tergesen was vice president and treasurer of BurCon Properties Limited, a real estate development and ownership company with assets in excess of $3 billion. Mr. Tergesen has been with the Burcon group of companies since December of 1995. Mr. Tergesen holds a B.A. in economics from the University of Winnipeg, an M.B.A. from McGill University, and is a member of the Canadian Institute of Chartered Accountants.

Rosanna Chau – Director

Ms. Chau is the Deputy Chairman and Managing Director of ITC Corporation Limited, a investment holding company which has interests in a diverse portfolio of businesses and the shares of which are listed on The Stock Exchange of Hong Kong Limited. She is responsible for ITC Corporation Limited’s operations and business development and has over 31 years of experience in international corporate management and finance. Ms. Chau holds a Bachelor’s Degree in Commerce at the University of Alberta and a Master’s Degree in Commerce at the University of New South Wales and has been awarded the Certificate in Traditional Chinese Medicine: A Way to Health at the Chinese University of Hong Kong. She has professional accounting qualifications and experience in different jurisdictions and is a fellow member of the Hong Kong Institute of Certified Public Accountants and the CPA Australia and a member of the Certified General Accountants’ Association of Canada. Ms. Chau is a member of the General Committee of The Chamber of Hong Kong Listed Companies, a non-profit organization serving listed companies and other industry bodies in Hong Kong. She was a director of Oxford Properties Group Inc. from July 1995 to October 2001. Ms. Chau was a director of BurCon Properties Limited from July 1997 to May 1998.




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Paul Westdal – Director

Mr. Westdal is a founder of B.M.W. Canola Inc., the Manitoba based company that developed the technology acquired by Burcon NutraScience Corporation in October 1999. Mr. Westdal is a professional agrologist, belonging to the Agricultural Institute of Canada. He is President of Agri-Tec International, a consortium of grain industry construction companies based in Winnipeg. Mr. Westdal was previously the Director of Marketing for the Canadian International Grains Institute and the Manager of the London, UK office of the Canadian Wheat Board. Mr. Westdal has over 32 years of experience marketing and developing sales of agricultural products around the world. Mr. Westdal holds Bachelor of Arts and Master of Science degrees from the University of Manitoba.

Lawrence Wang – Director

After an extensive teaching and research career, Dr. Wang retired in 2005 and became Professor Emeritus in the Department of Biological Sciences at the University of Alberta. Dr. Wang undertook his graduate studies in the United States and finished his Masters degree in Biology at Rice University, Houston, Texas, and his Ph.D. degree in Animal Physiology at Cornell University in Ithaca, New York in the 1960’s. Dr. Wang’s research involved energy and fat metabolism and the enhancement of cold tolerance in man, hibernation and hypothermia, and the influence of herbs (e.g. ginseng) on learning and memory, aging, exercise and obesity. His publications include five patents, five edited books, and over 150 original scientific research papers and reviews. He is the inventor of the Canadian Cold Buster bar and the Access bar, patented products based on his 18 years of research on energy and fat metabolism.

Dr. Wang has received numerous awards including the Innovative Technology of the Year, Alberta Science and Technology Leadership Award (1992), the Gordon Royal Maybee Award from the Canadian Institute of Food Science and Technology (1992), Elected Fellow, Academy of Sciences, Royal Society of Canada (FRSC, 1993), the highest honor achievable by academics in Canada and the Friendship Award, Government of China, for service to eco-rehabilitation and poverty alleviation in rural China (2006).

David Lorne John Tyrrell – Director

D. Lorne Tyrrell is the Canadian Institute of Health Research (CIHR)/Glaxo SmithKline Chair in Virology in the Department of Medical Microbiology and Immunology at the University of Alberta. Since 1986, he has focused his research on viral hepatitis. Supported by CIHR and Glaxo Canada, Dr. Tyrrell’s work on the development of antiviral therapy resulted in the licensing of the first oral antiviral agent to treat chronic hepatitis B infection – lamivudine - in 1998. Dr. Tyrrell holds




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22 international patents for his studies on viral hepatitis. Dr. Tyrrell was Dean of the Faculty of Medicine and Dentistry from 1994 – 2004 at the University of Alberta and is currently the Chair of the Board of Directors of the Gairdner Foundation. The Canada Gairdner International Awards recognizes excellence in medical science research globally. Dr. Tyrrell has received numerous prestigious awards including the Gold Medal of the Canadian Liver Foundation (2000), the FNG Starr Award of the Canadian Medical Association (2004) and the Principal Award of the Manning Awards Foundation (2005). Dr. Tyrrell was appointed Officer of the Order of Canada in 2002. In April 2010, D. Lorne Tyrrell was appointed as the inaugural director of the Li Ka Shing Institute of Virology at the University of Alberta. On April 28, 2011, Dr. Tyrrell was inducted to the Canadian Medical Hall of Fame.

Alan Chan – Director

Mr. Chan is an executive director of ITC Corporation Limited, ITC Properties Group Ltd., and PYI Corporation Limited. He is also an alternate (non-executive) director to Dr. Chan Kwok Keung, Charles, of PYI Corporation Limited, all in Hong Kong. At ITC Corporation Limited, Mr. Chan focuses on private equity, venture capital and corporate finance transactions across countries and industries. At ITC Properties Group Limited, Mr. Chan is involved with the investment and development of commercial, hospitality and residential projects across Asia. In addition, he is the lead in developing new policies for green and sustainable practices throughout the group. Mr. Chan is the director of corporate finance at PYI Corporation Limited. Mr. Chan is also currently an advisor to the BEE Inc. (Bisagni Environmental Enterprise). Prior to joining ITC, Mr. Chan worked in the Investment Banking Division of Goldman Sachs Group with a focus on capital raising, mergers & acquisitions and strategic advisory for financial institutions in Greater China and Southeast Asia. Mr. Chan is a graduate of Duke University majoring in Political Science - International Relations and minors in Philosophy and Economics.

Matthew Hall – Director

Matthew Hall is a marketing and consumer packaged goods veteran with unique expertise in step change marketing initiatives. Mr. Hall had a 31-year career with Nestle, the world’s largest food and beverages company. Having worked in several countries, including Nestle’s head office in Switzerland, he has gained extensive experience across continents, business functions and product categories. Mr. Hall has developed and implemented step change marketing, communications and sales capability initiatives, which were launched in Canada, rolled out globally and resulted in sustained growth and profit results for Nestle. As Managing Director/CEO, Food, Coffee and Beverages Division, Nestle U.K. from January 2008 to March 2010, Mr. Hall has initiated and implemented organizational re-designs and new product launches, introduced leading edge sustainability processes along




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with health, wellness and nutrition programs. He is currently an independent consultant, helping clients develop growth strategies and capabilities to become competitive and best-in-class organizations that work in sync to achieve their long-term vision.

J. Douglas Gilpin – Director

Douglas Gilpin, FCA, ICD.D., retired from the partnership of KPMG LLP in 1999. In 2008, Mr. Gilpin received a Life Service Award from The Institute of Chartered Accountants of Alberta in recognition of 40 years experience in delivering professional services to business and the community. During his 18 years tenure as a partner in Advisory Services at KPMG he served as an audit engagement partner. He was a member of the KPMG’s National Quality Assurance, the National Financial Institutions and Insurance Groups and he was the Quality Assurance Partner for the Edmonton office for 10 years. Mr. Gilpin has consulted on corporate governance, including compliance with the Sarbanes Oxley Act 404 and National Instrument 52-109 reporting for issuers listed on the TSX. Mr. Gilpin has served as a director of Canada Health Infoway (“CHI”) and a director of Afexa Life Sciences Inc. (“Afexa”), the makers of COLD-FX, where he served as lead director until June 2011. He has served as a director of The Institute of Health Economics of Alberta (“IHE”), Alberta Innovates Technology Futures (“AITF”) and in 2012 he was appointed to the Board of the Health Quality Council of Alberta (“HQCA”). He was the chair of the governance committee and a member of the audit committee of CHI, and is the Chair of the audit committee for each of IHE, AITF and HQCA. Mr. Gilpin is executive chair of The Inspections Group Inc., a privately owned company that performs safety code inspection services, building, plumbing and gas and electrical inspections in compliance with the Safe Codes Act of Alberta. Mr. Gilpin is a member of the Institute of Corporate Directors and recently received his ICD.D designation from the Institute. Mr. Gilpin was elected as Fellow of the Institute of Chartered Accountants of Alberta in 2012.

Bradford Allen - Director

Mr. Allen has over 30 years of experience in the investment, banking and securities industries. His career in private banking and investment banking includes working at major investment banks in both the institutional and private sectors in New York, Los Angeles and Hong Kong. Mr. Allen has raised private and institutional capital for companies in both the US and Hong Kong, as well as advising on mergers and acquisitions. Mr. Allen graduated with a business degree from Villanova University in 1978.




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Jade Cheng – Chief Financial Officer and Treasurer

Ms. Cheng has been with the Burcon group of companies since July 1995, holding various senior financial positions, including Vice-President, Group Audit and Corporate Secretary of BurCon Properties Limited until its merger with its controlled subsidiary, Oxford Properties Group Inc., in May 1998. Prior thereto, Ms. Cheng was a Manager with the General Practice group of the Vancouver office of Coopers & Lybrand, Chartered Accountants. Ms. Cheng holds a Bachelor’s Degree in Economics and a Master’s Degree in Business Administration from the University of British Columbia and is a member of the Canadian Institute of Chartered Accountants.

Randy Willardsen – Senior Vice-President, Process

Mr. Willardsen has over 28 years of experience in the fields of membrane filtration and food, dairy and biotechnology processes. Mr. Willardsen was the founder of Separation Technology, Inc., a leading supplier of membrane-based purification equipment and related services to the food industry with particular emphasis on dairy and beverage applications. Mr. Willardsen was also co-founder of both Inprotech Corporation, a supplier of high quality whey proteins to the U.S. market, and BioPlex Nutrition, a nutritional supplement company focused on formulated protein supplements. With BioPlex, he served as technical director, and oversaw manufacturing of all products until the company was sold in 1999. Most recently, Mr. Willardsen founded Gallo Protein, a partnership with Joseph Gallo Farms to produce highly purified whey protein isolates.

Mr. Willardsen has worked with Burcon since April of 2001, providing advisory services and technical reviews of the Company’s extraction technology. Mr. Willardsen holds a masters degree in Food Science and Nutrition from the University of Minnesota.

Dorothy Law – Senior Vice-President, Legal and Corporate Secretary

Ms. Law was a director of Burcon from December 1998 to April 2010. Ms. Law joined the Burcon group of companies in August 1997 and acted as corporate counsel. Prior thereto, she was an associate at the law firm of Lang Michener LLP, practising primarily in the areas of securities, corporate and commercial law. Ms. Law was called to the British Columbia Bar and admitted as a member of the Law Society of British Columbia in August 1996. Ms. Law holds a Bachelor of Laws degree and a Bachelor of Commerce degree from the University of British Columbia. Ms. Law was also admitted as a solicitor of the High Court of Hong Kong in May 1999. She is a non-practising member of the Law Society of Hong Kong.




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Martin Schweizer – Vice President, Technical Development

Dr. Schweizer joined Burcon in May 2002 as a process-engineering specialist. He relocated from Nancy, France, where he earned his doctorate at the Institut National Polytechnique de Lorraine, with an emphasis on the enzymatic hydrolysis of rapeseed proteins. Prior to his Ph.D. work, Dr. Schweizer studied chemical engineering at the University of Karlsruhe, Germany, where he specialized in food process engineering and water technology. Since January 2003, Dr. Schweizer has overseen Burcon’s research and development efforts at its Winnipeg Technical Centre.

Cease Trade Orders, Bankruptcies, Penalties or Sanctions

Other than as set out below, none of the directors or executive officers:

a) is, as at the date of the AIF, or was within 10 years before the date of the AIF, a director or chief executive officer or chief financial officer of any company (including Burcon) that:

i) was the subject of an order (as defined in National Instrument 51-102F2) that was issued while the director or executive officer was acting in the capacity as director, chief executive officer or chief financial officer; or

ii) was subject to an order that was issued after the director or executive officer ceased to be a director, chief executive officer, or chief financial officer, and which resulted from an event that occurred while that person was acting in the capacity as a director, chief executive officer, or chief financial officer.

None of the directors, executive officers or a shareholder holding a sufficient number of securities of the Company to affect materially the control of the Company,

b) is at the date hereof, or has been within 10 years before the date of this AIF, a director or executive officer of any company (including Burcon) that while that person was acting in that capacity, or within a year of that person ceasing to act in that capacity, became bankrupt, made a proposal under any legislation relating to bankruptcy or insolvency or was subject to or instituted any proceedings, arrangement or compromise with creditors or had a receiver, receiver manager or trustee appointed to hold its assets; or

c) has, within the 10 years before this AIF, become bankrupt, made a proposal under any legislation relating to bankruptcy or insolvency, or become subject to or instituted any proceedings, arrangement or compromise with creditors, or had a receiver, receiver manager or trustee appointed to hold the assets of the director, executive officer or shareholder.




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Ms. Rosanna Chau is the Deputy Chairman and Managing Director of ITC Corporation Limited ("ITC"), a company whose shares are listed on The Stock Exchange of Hong Kong Limited. On November 15, 2005 the Securities and Futures Commission (the "SFC") of Hong Kong criticized the board of directors of ITC for breaching Rule 21.3 of the Code on Takeovers and Mergers (the "Takeovers Code") in respect of the dealing in the securities of Hanny Holdings Limited ("Hanny") by ITC during an offer period without the consent of the Executive Director of the Corporate Finance Division of the SFC. Rule 21.3 of the Takeovers Code restricts share dealings and transactions by an offeror and parties acting in concert with it during securities exchange offers. Hanny was involved in a securities exchange offer announced in April 2005. Since ITC held over 20% of the shares of Hanny, it was presumed to be acting in concert with Hanny under the Takeovers Code. Ms. Rosanna Chau was then a director of ITC.

Mr. J. Douglas Gilpin was a director of ViRexx Medical Corp. (“ViRexx”) until his resignation from the board of directors of ViRexx on September 14, 2008. On November 18, 2008, trading in ViRexx shares was suspended by the Alberta Securities Commission for failure to file interim unaudited financial statements, interim management discussion and analysis, and certification of interim filings for the interim period ended September 30, 2008. Similar cease trade orders were issued by the securities regulatory authorities of British Columbia, Ontario and Quebec. On November 21, 2008, ViRexx announced that on October 16, 2008, ViRexx filed a Notice of Intention to make a proposal to its creditors pursuant to the Bankruptcy and Insolvency Act (Canada). On December 11, 2008, ViRexx announced the granting of a court order to reorganize ViRexx and to approve the proposal in the proposal proceedings under the Bankruptcy and Insolvency Act (Canada) and the Business Corporations Act (Alberta). On December 23, 2008, ViRexx announced that in accordance with the order for reorganization in such proposal proceedings, Paladin Labs Inc. had become the sole shareholder of ViRexx and that ViRexx would be taking steps necessary to cease being a reporting issuer in Canada and the United States.

Ms. Dorothy Law was a director of Brainium Technologies Inc. ("Brainium") from June 2001 to June 10, 2002. On May 29, 2002, the British Columbia Securities Commission issued a cease trade order against Brainium for failure to file a comparative financial statement for the financial year ended December 31, 2001, which was a required record under then section 145 of the Securities Rules, BC Reg. 194/97. The shares of Brainium were halted from trading on the TSX on June 4, 2002. On September 13, 2002, the shares of Brainium were suspended from trading on the TSX for failure to meet continued listing requirements.




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Conflicts of Interest

Ms. Rosanna Chau is the Deputy Chairman and Managing Director of ITC and Mr. Alan Chan is an executive director of ITC. Mr. Chan is the son of Dr. Chan Kwok Keung, Charles, who holds approximately 36% of the issued share capital of ITC. ITC indirectly owns, as at the date of this AIF, approximately 21% of the issued and outstanding shares of Burcon.

The Company rents its head office premises from and shares certain office equipment with a company related by virtue of a common shareholder and officers. During fiscal 2012, Burcon paid $56,587 (2011 – $40,777) to this company for the rental charges. In addition, administrative services are contracted through a management agreement with this related company and up to February 2011, the services of two of the Company’s officers were provided through this management agreement. For the year ended March 31, 2012, Burcon paid $37,940 (2011 –$165,563) for these services. From March 1, 2011 to March 31, 2012, professional services provided by Burcon to this related company provided income to Burcon of $18,951 (2011 - $2,093). These transactions, occurring in the normal course of operations, are measured at the exchange amount, which is the amount of consideration established and agreed to by the related parties.

TRANSFER AGENTS AND REGISTRARS

The Company’s co-transfer agents and co-registrars for its Common Shares are Computershare Investors Services Inc. at its principal transfer offices in Vancouver, British Columbia and Toronto, Ontario and Computershare Trust Company N.A. at its principal transfer office in Denver, Colorado.

MATERIAL CONTRACTS

The only material contracts Burcon entered into are the following which are available on SEDAR at www.sedar.com:

License and Production Agreement with ADM

On March 4, 2011, Burcon and Burcon’s wholly-owned subsidiary, Burcon NutraScience (MB) Corp. (together referred to for this section only, as “Burcon”) entered into a license and production agreement (the “License and Production Agreement”) with Archer Daniels Midland Company (“ADM”). Pursuant to the License and Production Agreement, Burcon has granted to ADM an exclusive, royalty-bearing, worldwide license (the “License”) to use and exploit Burcon’s soy protein technology solely to make, have made, use, market and sell soy protein products (the “Soy Products”) that use, incorporate or are derived from any Burcon technology. ADM has agreed to use reasonable commercial efforts to design, build and commission an initial production facility (the “Semi-works Production




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Facility”) within a specified amount of time after it receives permit approval from the US Environmental Protection Agency (“EPA Approval Date”) to manufacture the Soy Products. ADM will also, within a time specified under the License and Production Agreement, provide written notice to Burcon to advise whether it will or will not increase its annual production capacity of the Products beyond the capacity of the Semi-works Production Facility (“Full Commercial Production”). The License and Production Agreement provides each party the right to convert the exclusive license to a non-exclusive license under certain conditions.

In consideration of the License, ADM will pay to Burcon running royalties based on the net revenue (as defined in the License and Production Agreement) in relation to the sale of the Soy Products which fall within the scope of the Burcon Technology. ADM will pay quarterly royalties (the “Pre-production Royalty”) to Burcon from the EPA Approval Date until the first bona fide arms’ length sale of Products manufactured in the Semi-works Production Facility. Once such sale in the Semi-works Production Facility occurs, ADM will pay to Burcon royalties based on a percentage of net revenue from the sale of Products (the “Semi-works Production Royalty”). If ADM expands production to Full Commercial Production the royalty rate will be reduced to a lower percentage rate (the “Full Commercial Production Royalty”). The Full Commercial Production Royalty rate will be further reduced if ADM expands production and sale into certain geographic regions or if ADM achieves a pre-defined further expanded level of production capacity. The Semi-works Production Royalty and the Full Commercial Production Royalty rates may also be reduced if the exclusive license is converted to a non-exclusive license or if certain Burcon patents do not grant within a specified time.

If the exclusive license is converted to a non-exclusive license, Burcon will be entitled to make, have made, use, market and sell the Soy Products on a non-exclusive basis and to grant any such rights to any other person. ADM will grant to Burcon an irrevocable, non-exclusive, royalty bearing license, with a right to sublicense, to use ADM Improvements (as defined in the License and Production Agreement) to make, have made, use, market or sell the Soy Products worldwide. If the license is converted to a non-exclusive license and Burcon chooses to use ADM improvements, the aggregate royalties payable by Burcon to ADM in any year will not exceed the aggregate royalties payable by ADM to Burcon in the same year.

Under the License and Production Agreement, Burcon will be responsible for filing, prosecution and maintenance of Burcon patent rights in certain countries. Burcon will also be responsible for defending any action in which the validity of any Burcon patent right is raised in any jurisdiction.

Royalties payable under the License will terminate on the later of the date of expiry of the last to expire of the Burcon Patent Rights (as defined in the License and Production Agreement) and twenty years from March 4, 2011.




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License and Development Agreement with ADM

On September 16, 2003 (the "Effective Date"), Burcon and its wholly-owned subsidiary, Burcon NutraScience (MB) Corp. (together for this section only, referred to as "Burcon") entered into the License and Development Agreement with ADM. Under the License and Development Agreement, Burcon and ADM were to work together and coordinate development efforts in order to: (i) develop processes for producing canola protein isolate, special grades of canola protein or canola protein derivatives (collectively the "Products"); (ii) develop applications for the Products; and (iii) meet certain commercialization criteria agreed to between the parties.

Although Burcon and ADM obtained self-affirmed GRAS (Generally Recognized as Safe) status for Puratein® canola protein isolate and Superteincanola protein isolate, under the License and Development Agreement, ADM would use its best efforts to pursue GRAS notification and obtain a no-objection letter from the FDA for a Product (the "Approval Date").

ADM had the right to terminate the License and Development Agreement at any time up to the Approval Date. Thereafter, the License and Development Agreement may only be terminated by either party in the event that the royalty rate or minimum royalties cannot be agreed to between the parties or for a material breach of the other party’s obligations under the License and Development Agreement.

Upon completion of the development period set out in the License and Development Agreement and the parties’ agreement on the royalty rate and minimum royalties payable by ADM during the term of the License and Development Agreement (the "License Date"), Burcon would grant ADM an exclusive, royalty-bearing, worldwide license to use and exploit Burcon’s technology solely to make, have made, use, import and sell Products, together with certain rights to grant sublicenses. ADM would pay to Burcon royalties based on sales of Products by ADM, its affiliates, or sublicensees.

The term of the License and Development Agreement commenced on the Effective Date and extended until the later of: (a) the date of expiry of the last to expire of Burcon’s patents; and (b) twenty years from the License Date.

Under the License and Development Agreement, ADM had an option to license any improvements developed by Burcon to Burcon’s technology as well as any canola-based non-protein process derivatives developed by Burcon.

Burcon had obligations to maintain and prosecute its patents in certain countries specified in the License and Development Agreement as well as to defend or enforce Burcon’s patents.




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Amendments to License and Development Agreement

On June 19, 2007, Burcon announced that it had agreed to amend (the “First Amendment”) the License and Development Agreement. Under the terms of the amendment, the parties agreed to jointly fund the third-party expenses incurred in order to obtain GRAS notification status for Burcon’s canola protein isolate products. Under the amendment, Burcon and ADM would each contribute one-half of the expenses up to US$720,000. Burcon also agreed to contribute any additional amounts in excess of US$720,000, subject to a maximum of US$1,033,000 in the total cost for the regulatory process. Should the cost for the regulatory process exceed US$1,033,000, the parties would negotiate in good faith to determine each party’s obligation to contribute further funding. A total of US$946,000 had been expended, with Burcon’s share at US$586,000.

The First Amendment provided that either ADM or Burcon would reimburse the other on the occurrence of certain events. If ADM chose not to proceed with the license under the License and Development Agreement and terminated it in accordance with the specific provisions under the agreement, then Burcon would reimburse ADM for its share of the costs incurred in the regulatory process. Alternatively, if ADM chose to proceed with the license then ADM would reimburse Burcon for all of its costs incurred in the regulatory process.

On October 7, 2008, Burcon announced that its Puratein® canola protein isolate and Superteincanola protein isolate were self-affirmed GRAS for their intended use in a variety of food and beverage applications in the United States. GRAS status permits Burcon to market Puratein® canola protein isolate and Superteincanola protein isolate for use in an array of mainstream foods and beverages for human consumption. GRAS status is a standard set by the FDA for food ingredients to be accepted for use in foods and beverages. To enhance consumer acceptance of Puratein® canola protein isolate and Superteincanola protein isolate, Burcon and ADM announced on the same day that they chose to pursue GRAS notification for Puratein® canola protein isolate and Superteincanola protein isolate. GRAS notification is a voluntary procedure whereby a company informs the FDA of its determination that the use of a substance is GRAS. A substance is GRAS notified when, after reviewing the GRAS notification, the FDA responds with a no-objection letter if it is satisfied with the submission.

On January 19, 2010, Burcon announced that it had filed a formal notification in accordance with the FDA proposed regulation 62FR 18938, having determined, based on a review of the data referenced in the notification, that Burcon’s Puratein® canola protein isolate and Superteincanola protein isolate are GRAS for their intended use as an ingredient in a variety of food and beverage applications and in addition, that both substances are exempt from premarket approval requirements of the Food, Drug and Cosmetic Act (the “GRAS Notification”). In response to




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comments from the FDA, Burcon modified and resubmitted the GRAS Notification in February 2010. In a letter dated April 1, 2010, the FDA formally acknowledged receipt of the GRAS Notification. See "Obtaining Regulatory Approval for Marketing Puratein® and Supertein”.

On August 30, 2010, Burcon announced that the FDA issued a no objection letter with respect to Puratein® and Superteincanola protein isolates. This response indicates that the FDA has no objection to the conclusion that Puratein® and Superteinare GRAS among qualified experts for use alone or together as an ingredient in dairy products, grain products, fruit and vegetable juices and beverages, salad dressings, meal replacements and nutritional bars. See “Obtaining Regulatory Approval for Marketing Puratein® and Supertein”.

By an agreement dated as of November 11, 2010, Burcon and ADM agreed to amend (the “Second Amendment”) the License and Development Agreement. Under the terms of the Second Amendment, the parties agreed to extend the Development Period (as defined in the License and Development Agreement) under the License and Development Agreement to provide that the “Approval Date” in Section 2.2 would be deemed to be March 1, 2011. Pursuant to Section 2.7 of the License and Development Agreement, ADM may, during the Development Period but prior to the Approval Date, determine that it does not wish to continue with the development and commercialization of the Products and terminate the License and Development Agreement. However, pursuant to the Amendment, ADM agreed that it would not terminate the License and Development Agreement prior to March 1, 2011.

Under the terms of the License and Development Agreement, the parties must negotiate the terms of the license for Burcon’s canola protein isolates commencing on the Approval Date. The Second Amendment provided that if the parties do not come to agreement of the terms of the license on or before March 1, 2011, then the License and Development Agreement will terminate and Burcon shall reimburse ADM in the amount of $360,000, representing ADM’s portion of the costs associated with the process the parties undertook to obtain self-affirmed GRAS status and the no-objection letter from the U.S Food and Drug Administration for Burcon’s canola protein isolate products in the United States.

On March 4, 2011, Burcon and ADM entered into a further agreement to amend (the “Third Amendment”) the License and Development Agreement. Under the terms of the Third Amendment, the parties agreed to extend the Development Period under the License and Development Agreement to provide that the “Approval Date” in Section 2.2 would be deemed to be March 1, 2012. Burcon’s main research objective during the one-year term of this amendment was to further the development and commercialization potential of the Burcon’s canola protein products by further establishing their unique functional and nutritional




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characteristics. However, the parties did not reach an agreement prior to March 1, 2012. Therefore, the License and Development Agreement between Burcon and ADM has terminated.

In connection with the GRAS notification process to the FDA undertaken by ADM and Burcon for the Products, ADM contributed US$360,000 (“ADM’s Expenses”). Burcon agreed to reimburse ADM for ADM’s Expenses on March 1, 2012. Upon receipt by ADM of ADM’s Expenses, all results from the GRAS notification process will be owned by Burcon. Following the termination of the License and Development Agreement, Burcon reimbursed ADM in April 2012 for ADM’s share of the costs expended in the regulatory process.

Copies of the License and Production Agreement, the License and Development Agreement and the First, Second and Third Amendments to the License and Development Agreement are available on SEDAR at www.sedar.com.

INTERESTS OF EXPERTS

The Company’s consolidated financial statements for the year ended March 31, 2012 have been audited by PricewaterhouseCoopers LLP, Chartered Accountants, of Vancouver, British Columbia. PricewaterhouseCoopers LLP is independent of the Company in accordance with the rules of professional conduct of the Institute of Chartered Accountants of British Columbia which govern its professional activities in British Columbia.

AUDIT COMMITTEE AND DISCLOSURE UNDER NATIONAL INSTRUMENT 52-110

Under National Instrument 52-110 ("NI 52-110"), Burcon is required to disclose in its AIF certain information concerning the composition of its audit committee and its auditor. The audit committee carries out the various responsibilities set forth in its charter, a copy of which is attached to this AIF as Schedule "A".

Composition of the Audit Committee

The audit committee of Burcon is comprised of J. Douglas Gilpin, Lorne Tyrrell and Lawrence Wang. Mr. Gilpin is the chair of the audit committee. All members of the audit committee are financially literate. Under NI 52-110, an individual is "financially literate" if he has the ability to read and understand a set of financial statements that present a breadth and level of complexity of accounting




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issues that are generally comparable to the breadth and complexity of the issues that can reasonably be expected to be raised by Burcon’s financial statements. Mr. Gilpin is the chair of the audit committee. Mr. Gilpin was an audit engagement partner in Advisory Services at KPMG LLP (chartered accountants) for 18 years until 1999. In 2008, Mr. Gilpin received a Life Service Award from The Institute of Chartered Accountants of Alberta in recognition of 40 years experience in delivering professional services to business and the community and was elected as Fellow of the Institute of Chartered Accountants of Alberta in 2012. Dr. Tyrrell has served on the audit committees of the Institute of Health Economics. He was also the Dean of the Faculty of Medicine and Dentistry of the University of Alberta from 1994 to 2004, during which he was responsible for managing a budget of over $300 million. When Dr. Tyrrell retired from his position, the Faculty reported no debt or deficit. Dr. Wang is the inventor of the Canadian Cold Buster bar and the Access bar, a patented, technology-transferred product based on his 18 years of research on energy and fat metabolism. This “fat-conversion activity bar” is currently being marketed in the US, Canada, Australia, New Zealand, Taiwan, Hong Kong, Korea and the United Kingdom. Through these businesses, Dr. Wang has gained experience in reading and understanding financial statements that are generally comparable to the breadth and complexity of the issues that can reasonably be expected to be raised by Burcon’s financial statements. A member of the audit committee is "independent" if the member has no direct or indirect material relationship with Burcon, which could, in the view of Burcon’s board of directors, reasonably interfere with the exercise of a member’s independent judgement. All the members of the audit committee are independent.

Audit Committee Oversight

During the most recently completed financial year, all recommendations of the audit committee with respect to financial reporting and to nomination or compensation of Burcon’s external auditor were adopted by the board of directors.

Pre-Approval Policies and Procedures

The charter of the audit committee requires pre-approval of non-audit services provided by the external auditor of Burcon. The auditor was not engaged to provide any non-audit services during the most recently completed financial year.

External Auditor Service Fees

Fees billed by PricewaterhouseCoopers LLP ("PwC") to Burcon for audit services relating to the last two fiscal years are outlined in the following table.




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Nature of Services Fees billed by auditor for the
fiscal year ended March 31,
2012
Fees billed by auditor for the
fiscal year ended March 31,
2011
Audit Fees1 $61,500 $58,000
Audit-Related Fees2 37,000 $88,500
Tax Fees3 Nil Nil
All Other Fees4 10,000 27,500
Total $108,500 $174,000

Notes:

(1) "Audit Fees" include the aggregate fees billed by PwC relating to the respective fiscal year. Of the total Audit Fees paid, $6,500 (2011-$6,000) is recoverable from ITC Corporation Limited ("ITC"), a company with an approximate 21% interest in the Company, in connection with reporting to ITC’s auditors for their annual audit. The Audit Fees billed for the year ended March 31, 2011 increased from $38,000 as reported in the Company’s AIF dated June 21, 2011 to $58,000. Of the $58,000 reported above, $32,000 related to the audit of the Company’s financial statements for the year ended March 31, 2011 prepared in accordance with Generally Accepted Accounting Principles, $6,000 related to the reporting to ITC’s auditors for their annual audit, and $20,000 related to the audit of the Company’s financial statements for years ended March 31, 2011 and March 31, 2010 prepared in accordance with International Financial Reporting Standards (“IFRS Statements”). The IFRS Statements were prepared in connection with the Company’s listing of its common shares on NASDAQ in October 2011.

(2) "Audit-Related Fees" include the aggregate fees billed for the respective fiscal year for assurance and related services by PwC that are reasonably related to the performance of the audit or review of Burcon’s financial statements and are not reported under "Audit Fees". The Audit-Related Fees billed for the year ended March 31, 2011 increased from Nil as reported in the Company’s AIF dated June 21, 2011 to $88,500. These fees related to audit services performed by PwC in connection with the Company’s listing of its common shares on NASDAQ in October 2011. Of the $88,500, $25,000 related to the audit of the opening IFRS balance sheet as at April 1, 2009, $15,000 related to the review of each of the Company’s interim financial statements for the first three quarters of the year ended March 31, 2011 and $48,500 related to other assurance and related services in connection with the filing of the Company’s Form 40F with the United States Securities and Exchange Commission.

(3) "Tax Fees" include the aggregate fees billed for the respective fiscal year for professional services rendered by PwC for tax compliance, tax advice, and tax planning.

(4) "All Other Fees" include the aggregate fees billed for the respective fiscal year for products and services provided by PwC, other than the services reported under "Audit Fees", "Audit-Related Fees" and "Tax Fees". All Other Fees billed for the year ended March 31, 2011 increased from Nil as reported in the Company’s AIF dated June 21, 2011 to $27,500. Of the $27,500, $5,500 related to the analysis of revenue recognition issues under the License and Production Agreement with ADM. The balance of these fees related to other services performed by PwC in connection with the Company’s listing of its common shares on NASDAQ in October 2011.




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ADDITIONAL INFORMATION

Additional information relating to Burcon can be found on the SEDAR website at www.sedar.com.

Additional information, including directors’ and officers’ remuneration and indebtedness, principal holders of Burcon’s securities and securities authorized for issuance under equity compensation plans, is contained in Burcon’s Management Proxy Circular dated July 20, 2011 for its most recent annual meeting of shareholders that involved the election of directors.

Additional financial information is provided in Burcon’s financial statements and MD&A for its most recently completed financial year ended March 31, 2012.




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GLOSSARY

In this Annual Information Form, the following terms have the meanings set forth herein:

ADM Archer-Daniels-Midland Company
 
Affiliate has the meaning set out in the Canada Business Corporations Act
 
albumin

refers generally to any protein with water solubility, which is moderately soluble in concentrated salt solutions, and experiences heat coagulation (protein denaturation). Substances containing albumin, such as egg white, are called albuminoids

 
BMW B.M.W. Canola Inc.
 
Board the Board of Directors of the Company
 
Burcon or Company Burcon NutraScience Corporation
 
Burcon-MB

Burcon Nutrascience (MB) Corp. (formerly B.M.W. Canola Inc.), a corporation incorporated under the laws of Manitoba and a wholly-owned subsidiary of Burcon

 
CLARISOY

the trade-marked brand name for Burcon’s soy protein. CLARISOYis a trademark of ADM and is licensed to Burcon

 
Common Share or Shares a common share in the capital of the Company
 
erucic acid fatty acids contained in canola, but not considered essential for human growth
 
FAO the Food and Agricultural Organization
 
FDA the United States Food and Drug Administration
 
globulin

this generic term encompasses a heterogeneous series of families of proteins, with larger molecules and less soluble in pure water than albumin. Globular proteins, or spheroproteins are one of the two main protein classes, comprising "globe"-like proteins that are more or less soluble in aqueous solutions (where they form colloidal

 




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  solutions)
 
glucosinolates the sulphur compounds that give mustards their sharp taste
 
GM genetically modified
 
GMO genetically modified organism
 
GRAS generally recognized as safe
 
License and Development Agreement

the License and Development Agreement dated September 16, 2003 made among Burcon, Burcon-MB and ADM

 
License and Production
Agreement

The License and Production Agreement dated March 4, 2011 made among Burcon, Burcon-MB and ADM

 
NASDAQ The NASDAQ Global Market
 
Nutratein

the trade-marked brand name for Burcon’s blended cruciferin-rich and napin-rich canola protein isolates

 
PDCAAS protein digestibility corrected amino acid score
 
PEAZAZZ the trade-marked brand name for Burcon’s pea protein
 
Puratein® the trade-marked brand name for Burcon’s cruciferin-rich canola protein isolate
 
Supertein the trade-marked brand name for Burcon’s napin-rich canola protein isolate
 
TSX Toronto Stock Exchange
 
U.S. or United States the United States of America
 
Winnipeg Technical Centre

the premises where Burcon’s research laboratory and pilot plant operations are located

 




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SCHEDULE "A"

BURCON NUTRASCIENCE CORPORATION (“BURCON”)

AUDIT COMMITTEE CHARTER

General Functions, Authority and Role

The purpose of the audit committee is to oversee the accounting and financial reporting process of Burcon and the audits of its financial statements, and thereby assist the Board of Directors of Burcon in monitoring (1) the integrity of the financial statements of Burcon, (2) compliance by Burcon with legal and regulatory requirements related to financial reporting, (3) the performance of Burcon’s external auditors, and (4) the performance of Burcon’s internal controls and financial reporting process.

The audit committee has the power to conduct or authorize investigations into any matters within its scope of responsibilities, with full access to its auditors and its legal advisors and to all books, records, facilities and personnel of Burcon. In connection with such investigations or otherwise in the course of fulfilling its responsibilities under this charter, the audit committee has the authority to independently retain special legal, accounting, or other consultants to advise it, and may request any officer or employee of Burcon, its independent legal counsel or independent auditor to attend a meeting of the audit committee or to meet with any members of, or consultants to, the audit committee. Burcon shall provide appropriate funding, as determined by the audit committee, for payment of (i) compensation to the external auditor to prepare and issue an audit report or perform other audit, review or attest services for Burcon, (ii) compensation to any outside advisors employed by the audit committee, and (iii) ordinary administrative expenses of the audit committee that are necessary or appropriate in carrying out the audit committee’s duties.

Burcon’s independent auditor is ultimately accountable to the audit committee, who, in its capacity as a committee of Burcon’s board of directors, is directly responsible for appointing, retaining and determining the appropriate compensation of the external auditor. The audit committee must also oversee the work of the external auditor engaged for the purpose of preparing or issuing an audit report or performing other audit, review or attest services for Burcon, including resolution of disagreements between management and the external auditor regarding financial reporting. The external auditor must report directly to the audit committee. In the course of fulfilling its specific responsibilities hereunder, the audit committee must maintain free and open communication between Burcon’s external auditors, Board of Directors and Burcon management. The responsibilities of a member of the audit committee are in addition to such member’s duties as a member of the Board of Directors.




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Membership

The audit committee of the board of directors of Burcon shall consist of a minimum of three directors. Members of the audit committee shall be directors appointed by the board of directors and may be removed by the board of directors at its discretion.

All members of the audit committee shall satisfy the independence and audit committee composition requirements of all applicable corporate and securities laws and stock exchange listing standards; provided, however, that one or more members may be non-independent within the meaning of all applicable regulations.

All members of the audit committee must be financially literate, i.e. have the ability to read and understand a set of financial statements that present a breadth and level of complexity of accounting issues that are generally comparable to the breadth and complexity of the issues that can reasonably be expected to be raised by Burcon's financial statements. At least one member shall be a financial expert.

The members of the audit committee shall elect, amongst themselves, one member to act as chairperson on an annual basis.

Responsibilities

The audit committee is responsible for:

  • reviewing Burcon’s interim and annual financial statements and management’s discussion and analysis related thereto, and all annual and interim earnings press releases before they are publicly disclosed;

  • ensuring that adequate procedures are in place for the review of Burcon's public disclosure of financial information extracted or derived from Burcon's financial statements, other than management's discussion and analysis and annual and interim earnings press releases, and periodically reviewing and updating such procedures;

  • establishing procedures for the receipt, retention and treatment of complaints received by Burcon regarding accounting, internal accounting controls, or auditing matters;

  • establishing procedures for the confidential, anonymous submission by employees of Burcon of concerns regarding questionable accounting or auditing matters;

  • reviewing and approving Burcon's hiring policies regarding partners, employees and former partners and employees of the present and former auditor of Burcon;

  • reviewing with management, Burcon’s major financial risk exposures and the steps management has taken to monitor and control such exposures;




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  • assessing risk areas and policies to manage risk;

  • overseeing the work of Burcon’s external auditors engaged for the purpose of preparing or issuing an audit report or related work;

  • ensuring Burcon’s external auditors report directly to the audit committee throughout the term of their appointment;

  • ensuring Burcon’s external auditors provide a formal written statement delineating all relationships between the external auditor and Burcon, actively engaging in a dialogue with the external auditor with respect to any disclosed relationships or services that may impact the objectivity and independence of the external auditor and for taking, or recommending that Burcon’s full board of directors take, appropriate action to oversee the independence of the external auditor;

  • pre-approving all non-audit services to be provided to Burcon or Burcon’s subsidiaries by Burcon’s external auditor;

  • recommending to Burcon’s board of directors the external auditor to be nominated for the purpose of preparing or issuing an auditor’s report (or any related work), as well as the compensation to be paid to the external auditor;

  • annually reviewing and reassessing the adequacy of this charter and recommend any proposed changes to the Board of Directors for approval;

  • reporting committee actions to the Board of Directors with such recommendations as the committee may deem appropriate; and

  • providing copies of meeting of the audit committee to the Board of Directors.

The audit committee does the following main things to discharge these responsibilities:

  • meeting with management and the external auditors at least two times per year;

  • meeting separately with each of management and the external auditors several times per year as required;

  • reviewing and approving the annual audit scope and the annual audit plan proposed by the auditors;

  • reviewing carefully and acting on all internal control points raised by the auditors in correspondence with management; and

  • discussing Burcon’s compliance with tax and financial reporting rules as issues arise.