Exhibit B

JOINT FILING STATEMENT

I, the undersigned, hereby express my agreement that the attached Schedule 13D (and any amendments thereto) relating to the common stock of Critical Therapeutics, Inc. is filed on behalf of each of the undersigned.

Dated: February 13, 2006
PROSPECT VENTURE PARTNERS III, L.P.
By: Prospect Management Co. III, L.L.C.
Its:		General Partner
		By:	/s/ David Schnell
		Name:	David Schnell
		Title:	Managing Director
PROSPECT MANAGEMENT CO. III, L.L.C.
	By:		/s/ David Schnell
	Name:		David Schnell
	Title:		Managing Director

/s/ David Schnell David Schnell

/s/ Alexander E. Barkas Alexander E. Barkas

/s/ Russell C. Hirsch Russell C. Hirsch

/s/ James B. Tananbaum James B. Tananbaum

14.