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Note 15 - Related Party Transactions (Details Textual) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Mar. 31, 2019
Mar. 10, 2016
Chairman of Eontec [Member] | Minimum [Member]            
Beneficial Ownership Percentage         5.00%  
Eontec [Member] | License Agreement [Member]            
Related Party Transaction, Amounts of Transaction $ 0 $ 48,000 $ 0 $ 53,000    
The 2016 Purchase Agreement [Member]            
Common Stock Purchase Agreement, Number of Shares Authorized to Issue and Sell to Investors           405,000,000
Common Stock Purchase Agreement, Value of Shares Authorized to Issue and Sell to Investors           $ 63,400,000