September 14, 2021

Division of Corporation Finance

Office of Life Sciences

Securities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

Re: Ontrak, Inc.

Registration Statement on Form S-3

File No. 333-259329

Ladies and Gentlemen:

Ontrak, Inc. hereby requests that the effective date and time of the above referenced Registration Statement be accelerated to 5:00 pm on September 16, 2021 or as soon thereafter as practicable, pursuant to Rule 461 of the Securities Act of 1933, as amended.

Very truly yours,

ONTRAK, INC.

By: /s/ Brandon H. LaVerne_______________

Name: Brandon H. LaVerne

Title: Chief Financial Officer