UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

____________________________

FORM 10-Q

QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)

OF THE SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended September 30, 2010

Commission File Number 001-31932

___________________________

HYTHIAM, INC.

(Exact name of registrant as specified in its charter)

____________________________

Delaware	88-0464853
(State or other jurisdiction of incorporation or organization)	(I.R.S. Employer Identification No.)

11150 Santa Monica Boulevard, Suite 1500, Los Angeles, California 90025

(Address of principal executive offices, including zip code)

(310) 444-4300

(Registrant's telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

Yes þ          No o

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).    

Yes þ          No o

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, or a non-accelerated filer or a smaller reporting company. See definitions of ‘‘accelerated filer,” “large accelerated filer,’’ and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

Large accelerated filer o     Accelerated filer o     Non-accelerated filer o     Smaller reporting company þ

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

Yes o            No þ

As of November 17, there were 182,029,048 shares of registrant's common stock, $0.0001 par value, outstanding.

1

TABLE OF CONTENTS

PART I - FINANCIAL INFORMATION			3
	ITEM 1.  Consolidated Financial Statements		3
		Condensed Consolidated Balance Sheets as of September 30, 2010
		and December 31, 2009	3
		Condensed Consolidated Statements of Operations for the
		Three and Nine Months Ended September 30, 2010 and 2009	4
		Condensed Consolidated Statements of Cash Flows for the
		Nine Months Ended September 30, 2010 and 2009	5
		Notes to Condensed Consolidated Financial Statements	7
	ITEM 2.  Management's Discussion and Analysis of Financial
		Condition and Results of Operations	26
	ITEM 3.  Quantitative and Qualitative Disclosures About Market Risk		36
	ITEM 4.  Controls and Procedures		36
PART II – OTHER INFORMATION			II-1
	ITEM 1.  Legal Proceedings		II-1
	ITEM 2.  Unregistered Sales of Equity Securities and Use of Proceeds		II-1
	ITEM 3.  Defaults Upon Senior Securities		II-1
	ITEM 4.  [Removed and Reserved]		II-1
	ITEM 5.  Other Information		II-1
	ITEM 6.  Exhibits		II-2
SIGNATURES			II-3
EXHIBIT 10.33
EXHIBIT 10.34
EXHIBIT 10.35
EXHIBIT 31.1
EXHIBIT 31.2
EXHIBIT 32.1
EXHIBIT 32.2

2

PART I - FINANCIAL INFORMATION

Item 1.                 Consolidated Financial Statements

HYTHIAM, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS

(In thousands,except for number of shares)	September 30,			December 31,
	2010			2009
ASSETS	(unaudited)
Current assets
Cash and cash equivalents	$	363		$	4,595
Marketable securities, at fair value		-			9,468
Receivables, net		73			308
Prepaids and other current assets		57			989
Total current assets		493			15,360
Long-term assets
Property and equipment, net of accumulated depreciation
of $7,093 and $6,697 respectively		311			877
Intangible assets, net of accumulated amortization of
$1,879 and $1,702 respectively		2,482			2,658
Deposits and other assets		196			210
Total Assets	$	3,482		$	19,105
LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities
Accounts payable	$	1,809		$	2,266
Accrued compensation and benefits		912			941
Other accrued liabilities		1,228			2,431
Short-term debt					9,643
Total current liabilities		3,949			15,281
Long-term liabilities
Deferred rent and other long-term liabilities		88			46
Warrant liabilities		72			1,089
Capital lease obligations		7			48
Total liabilities		4,116			16,464
Stockholders' equity
Preferred stock, $.0001 par value; 50,000,000 shares authorized;
no shares issued and outstanding		-			-
Common stock, $.0001 par value; 200,000,000 shares authorized;
81,424,000 and 65,283,000 shares issued and outstanding
at September 30, 2010 and December 31, 2009, respectively		8			7
Additional paid-in-capital		189,671			184,715
Accumulated other comprehensive income		-			696
Accumulated deficit		(190,313	)		(182,777	)
Total Stockholders' Equity		(634	)		2,641
Total Liabilities and Stockholders' Equity	$	3,482		$	19,105

See accompanying notes to the financial statements.

3

HYTHIAM, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS

(unaudited)

	Three Months Ended						Nine Months Ended
(In thousands, except per share amounts)	September 30,						September 30,
	2010			2009			2010			2009
Revenues
Total revenues	$	104		$	268		$	338		$	1,346
Operating expenses
Cost of healthcare services		99			68			174			502
General and administrative		2,581			3,878			9,254			14,007
Impairment losses		1			-			39			1,113
Depreciation and amortization		204			273			705			979
Total operating expenses		2,885			4,219			10,172			16,601
Loss from operations		(2,781	)		(3,951	)		(9,834	)		(15,255	)
Interest and other income		1			19			129			142
Interest expense		(41	)		(221	)		(312	)		(999	)
Loss on extinguishment of debt		-			(54	)		-			(330	)
Gain on the sale of marketable securities		-			160			696			160
Other than temporary impairment of marketable
securities		(32	)		(25	)		-			(185	)
Change in fair value of warrant liability		913			(4,767	)		1,807			(4,683	)
Loss from continuing operations before provision
for income taxes		(1,940	)		(8,839	)		(7,514	)		(21,150	)
Provision for income taxes		2			3			22			13
Loss from continuing operations	$	(1,942	)	$	(8,842	)	$	(7,536	)	$	(21,163	)
Discontinued Operations:
Results of discontinued operations, net of tax		-			-			-			10,449
Net income (loss)	$	(1,942	)	$	(8,842	)	$	(7,536	)	$	(10,714	)
Basic and diluted net income (loss) per share:
Continuing operations	$	(0.02	)	$	(0.16	)	$	(0.10	)	$	(0.38	)
Discontinued operations		-			-			-			0.19
Net income (loss) per share	$	(0.02	)	$	(0.16	)	$	(0.10	)	$	(0.19	)
Weighted number of shares outstanding		79,685			56,373			72,195			55,509

See accompanying notes to the financial statements.

4

HYTHIAM, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(unaudited)

	Nine Months Ended
(In thousands)	September 30,
	2010			2009
Operating activities
Net loss	$	(7,536	)	$	(10,714	)
Adjustments to reconcile net loss to net cash used in operating activities:
(Income) from Discontinued Operations	$	-			(10,449	)
Depreciation and amortization		706			978
Amortization of debt discount and issuance costs included in
interest expense		147			735
Other than temporary impairment on marketable securities		-			185
Gain on sale of marketable securities		(696	)		(159	)
Provision for doubful accounts		35			493
Deferred rent		(269	)		88
Share-based compensation expense		2,965			3,465
Loss on debt extinguishment		-			230
Fair value adjustment on warrant liabilitiy		(1,807	)		4,684
Impairment losses		37			1,113
Loss on disposition of assets		-			16
Changes in current assets and liabilities:
Receivables		200			(52	)
Prepaids and other current assets		45			169
Accounts payable		(180	)		(1,733	)
Long term accrued liabilities		-			6
Net cash used in operating activities of continuing operations		(6,353	)		(10,945	)
Net cash used in operating activities of discontinued operations		-			(1,103	)
Net cash used in operating activities		(6,353	)		(12,048	)
Investing activities
Proceeds from sales and maturities of marketable securities	$	10,225		$	1,420
Proceeds from sales of property and equipment		1			13
Proceeds from disposition of CompCare		-			1,500
Restricted cash		-			24
Purchases of property and equipment		(1	)		(17	)
Deposits and other assets		-			16
Net cash from investing activities by continuing operations		10,225			2,956
Net cash from investing activities by discontinued operations		-			39
Net cash provided by investing activities		10,225			2,995

(continued on next page)

5

HYTHIAM, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(unaudited)

(continued from previous page)

	Nine Months Ended
(In thousands)	September 30,
	2010	2009

Financing activities
Proceeds from the issuance of common stock and warrants	$	2,000		$	7,000
Costs related to the issuance of common stock and warrants		(275	)		(683	)
Proceeds from line of credit		450			2,072
Paydown on line of credit		(6,908	)		(1,346	)
Paydown on senior secured note		(3,332	)		(1,668	)
Capital lease obligations		(39	)		(74	)
Net cash provided by (used in) financing activities.
		(8,104	)		5,301
Net cash from (used in) financing activities by discontinued
operations		-			(73	)
Net cash from (used in) financing activities		(8,104	)		5,228
Net decrease in cash and cash equivalents for continuing operations		(4,232	)		(2,688	)
Net decrease in cash and cash equivalents for discontinued operations		-			(1,137	)
Net decrease in cash and cash equivalents		(4,232	)		(3,825	)
Cash and cash equivalents at beginning of period		4,595			10,893
Cash and cash equivalents at end of period	$	363		$	7,068
Supplemental disclosure of cash paid
Interest	$	154		$	197
Income taxes	$	51		$	77
Supplemental disclosure of non-cash activity
Common stock issued for outside services	$	271		$	168
Common stock issued for settlement of payables	$	1,235		$	-

See accompanying notes to the financial statements.

6

Hythiam, Inc. and Subsidiaries

Notes to Condensed Consolidated Financial Statements

(unaudited)

Note 1.   Basis of Consolidation, Presentation and Going Concern

The accompanying unaudited interim condensed consolidated financial statements as of September 30, 2010 and for the three and nine months ended September 30, 2010 and 2009, for Hythiam, Inc. (referred to herein as the Company, Hythiam, we, us or our) and our subsidiaries have been prepared in accordance with the Securities and Exchange Commission (SEC) rules for interim financial information and do not include all information and notes required for complete financial statements. In our opinion, all adjustments, consisting of normal recurring accruals, considered necessary for a fair presentation of the financial position of the Company as of September 30, 2010, results of operations for the three and nine months ended September 30, 2010 and 2009, and cash flows for the nine months ended September 30, 2010 and 2009 have been included. Interim results are not necessarily indicative of the results that may be expected for the entire fiscal year. The accompanying financial information should be read in conjunction with the financial statements and the notes thereto in our most recent Annual Report on Form 10-K for the year ended December 31, 2009. Amounts as of December 31, 2009 are derived from those audited consolidated financial statements.

Our financial statements have been prepared on the basis that we will continue as a going concern. At September 30, 2010, cash and cash equivalents amounted to $363,000 and we had a working capital deficit of approximately $3.5 million. We have incurred significant operating losses and negative cash flows from operations since our inception. During the nine months ended September 30, 2010, our cash used in operating activities amounted $5.4 million. We could continue to incur negative cash flows and net losses for the next twelve months. The financial statements do not include any adjustments relating to the recoverability of the carrying amount of the recorded assets or the amount of liabilities that might result from the outcome of this uncertainty. As of September 30, 2010, these conditions raised substantial doubt as to our ability to continue as a going concern.

In October 2010, the Company entered into Securities Purchase Agreements with accredited investors, including Socius Capital Group, LLC, an affiliate of our Chairman and CEO, for $500,000 of senior secured convertible notes and warrants to purchase shares of our common stock (see Note 7 Subsequent Events). In November 2010, the Company completed a private placement with accredited investors, including Socius Capital Group, LLC, an affiliate of our Chairman and CEO, and one other Hythiam director in the amount of $6.9 million including the conversion of the October senior secured convertible notes (see Note 7 Subsequent Events).

Our ability to fund our ongoing operations and continue as a going concern is dependent on signing and generating revenue from new Catasys contracts and the success of management’s plans to increase revenue and continue to decrease expenses. Beginning in the fourth quarter of 2008, and continuing through 2010, management has taken actions that have resulted in reducing annual operating expenses. We have, and continue to, renegotiated certain leasing and vendor agreements to obtain more favorable pricing and to restructure payment terms with vendors (see Note 6 Commitments and Contingencies).  In August 2010 we amended the lease for our managed treatment center to extend the lease by six months. The lease was set to expire in August 2010.  Under the terms of the amendment we reduced the square footage leased and decreased the monthly cost to approximately $7,100 per month which represented a 78% reduction in the monthly cost versus the first six months of 2010.  This extension allowed us to reduce existing costs while avoiding additional costs that would have been associated with moving to a new facility and avoid the potential disruption to revenues. In previous quarters, we have exited markets in our licensee operations that we have determined will not provide short-term profitability.  We may exit additional markets in our licensee operations and further curtail or restructure our managed treatment center to reduce costs if management determines that those markets will not provide short-term profitability and/or positive cash flow. We do not expect any direct costs associated with streamlining our organization further to have a material impact on our cash position or our ability to continue as a going concern.

7

We are pursuing additional Catasys contracts and are seeking to increase revenue from both our Catasys and private pay businesses.  We are currently implementing the recently signed contract in Nevada, which is expected to become operational in the fourth quarter of 2010.

Pursuant to a Stock Purchase Agreement between WoodCliff (our wholly-owned subsidiary) and Core Corporate Consulting Group, Inc., dated January 14, 2009, and effective as of January 20, 2009, we have disposed of our entire interest in our controlled subsidiary, Comprehensive Care Corporation (CompCare), consisting of 14,400 shares of Class A Series Preferred Stock, and 1,739,130 shares of common stock of CompCare held by Woodcliff, for aggregate gross proceeds of $1.5 million. We did not present CompCare as “held for sale” at December 31, 2008 since all of the criteria specified by SFAS 144, Accounting for the impairment or Disposal of Long-Lived Assets (SFAS 144), had not been met as of that date. The financial statements and footnotes present the operations, assets, liabilities and cash flows of CompCare as a discontinued operation. See Note 5 Discontinued Operations for further discussion.

Based on the provisions of the management services agreement (MSA) between us and our managed professional medical corporation, we have determined that it constitutes a variable interest entity, and that we are the primary beneficiary as defined in Financial Accounting Standards Board (FASB) Interpretation No. 46R, Consolidation of Variable Interest Entities, an Interpretation of Accounting Research Bulletin No. 51 (FIN 46R).  Accordingly, we are required to consolidate the revenue and expenses of our managed professional medical corporation. See Management Service Agreements heading under Note 2 Summary of Significant Accounting Policies for more discussion.

All intercompany transactions and balances have been eliminated in consolidation.

Note 2.   Summary of Significant Accounting Policies

Revenue Recognition

Healthcare Services

Our healthcare services revenues to date have been primarily derived from licensing our PROMETA Treatment Program and providing administrative services to hospitals, treatment facilities and other healthcare providers, and from revenues generated by our managed treatment centers. We record revenues earned based on the terms of our licensing and management contracts, which requires the use of judgment, including the assessment of the collectability of receivables. Licensing agreements typically provide for a fixed fee on a per-patient basis, payable to us following the providers’ commencement of the use of our program to treat patients. For revenue recognition purposes, we treat the program licensing and related administrative services as one unit of accounting. We record the fees owed to us under the terms of the agreements at the time we have performed substantially all required services for each use of our program, which for the significant majority of our license agreements to date is in the period in which the provider begins using the program for medically directed and supervised treatment of a patient and, in other cases, is at the time that medical treatment has been completed. 

The revenues of our managed treatment center, which we include in our consolidated financial statements, are derived from charging fees directly to patients for medical treatments, including the PROMETA Treatment Program. Revenues from patients treated at the managed treatment center are recorded based on the number of days of treatment completed during the period as a percentage of the total number treatment days for the PROMETA Treatment Program. Revenues relating to the continuing care portion of the PROMETA Treatment Program are deferred and recorded over the period during which the continuing care services are provided.

8

Behavioral Health

Our Catasys contracts are generally designed to provide revenues in the form of member fees and service revenues on a monthly basis. Some of our contracts include performance guarantees and we will defer revenues until the performance measurement period is completed and we have met all the conditions necessary to record revenues.

Cost of Healthcare Services

Healthcare Services

Cost of healthcare services represent direct costs that are incurred in connection with licensing our treatment programs and providing administrative services in accordance with the various technology license and services agreements, and are associated directly with the revenue that we recognize. Consistent with our revenue recognition policy, the costs associated with providing these services are recognized, for a significant majority of our agreements, in the period in which patient treatment commences, and in other cases, at the time treatment has been completed. Such costs include royalties paid for the use of the PROMETA Treatment Program for patients treated by all licensees, and direct labor costs, continuing care expense, medical supplies and program medications for patients treated at the managed treatment center.

Behavioral Health

Behavioral health cost of services is recognized in the period in which an eligible member actually receives services. Our Catasys subsidiary contracts with various healthcare providers, including licensed behavioral healthcare professionals, on a contracted basis. We determine that a member has received services when we receive a claim within the contracted timeframe with all required billing elements correctly completed by the service provider.

Comprehensive Income (Loss)

Our comprehensive loss is as follows:

	Three Months Ended						Nine Months Ended
(In thousands)	September 30,						September 30,
	2010			2009			2010			2009
Net income (loss)	$	(1,910	)	$	(8,842	)	$	(7,536	)	$	(10,714	)
Other comprehensive gain:
Net unrealized gain (loss) on marketable securities available for sale		-			14			-		$	467
Net realized gain on marketable securities included in loss from continuing operations		-			(30	)	$	(696	)	$	(30	)
Comprehensive income (loss)	$	(1,910	)	$	(8,858	)	$	(8,232	)	$	(10,277	)

Basic Income (Loss) per Share

Basic income (loss) per share is computed by dividing the net income (loss) to common stockholders for the period by the weighted average number of common shares outstanding during the period. Diluted income per share is computed by dividing the net income for the period by the weighted average number of common and dilutive common equivalent shares outstanding during the period.

Common equivalent shares, consisting of 25,962,675 and 29,349,000 of incremental common shares as of September 30, 2010 and 2009, respectively, issuable upon the exercise of stock options and warrants have been excluded from the diluted earnings per share calculation because their effect is anti-dilutive.

9

Share-Based Compensation

The Hythiam, Inc. 2003 Stock Incentive Plan and 2008 Stock Incentive Plan (the Plans), both as amended, provide for the issuance of up to 15 million shares of our common stock. Incentive stock options (ISOs) under Section 422A of the Internal Revenue Code and non-qualified options (NSOs) are authorized under the Plans. We have granted stock options to executive officers, employees, members of our board of directors, and certain outside consultants. The terms and conditions upon which options become exercisable vary among grants, but option rights expire no later than ten years from the date of grant and employee and board of director awards generally vest over three to five years. At September 30, 2010, we had 10,988,000 vested and unvested shares outstanding and 3,117,000 shares available for future awards.

Share-based compensation expense attributable to continuing operations amounted to $800,000 and $3 million respectively for the three and nine months ended September 30, 2010, compared to $1 million and $3.5 million respectively for the three and nine months ended September 30, 2009. This includes share-based compensation expense attributable to continuing operations recognized for employees and directors discussed below.

Stock Options – Employees and Directors

We measure and recognize compensation expense for all share-based payment awards made to employees and directors based on estimated fair values on the date of grant. We estimate the fair value of share-based payment awards using the Black Scholes option-pricing model. The value of the portion of the award that is ultimately expected to vest is recognized as expense over the requisite service periods in the consolidated statements of operations subsequent to January 1, 2006. We accounted for share-based awards to employees and directors using the intrinsic value method under previous FASB rules, allowable prior to January 1, 2006. Under the intrinsic value method, no share-based compensation expense had been recognized in our consolidated statements of operations for awards to employees and directors because the exercise price of our stock options equaled the fair market value of the underlying stock at the date of grant.

Share-based compensation expense attributable to continuing operations recognized for employees and directors for the three and nine months ended September 30, 2010 and 2009 amounted to $800 thousand  and $3 million compared to $910,000 and $3.2 million, respectively.

Share-based compensation expense recognized in our consolidated statements of operations for the three and nine months ended September 30, 2010 and 2009 includes compensation expense for share-based payment awards granted prior to, but not yet vested, as of January 1, 2006 based on the grant date fair value estimated in accordance with the pro-forma provisions of SFAS 123, and for the share-based payment awards granted subsequent to January 1, 2006 based on the grant date fair value estimated in accordance with the provisions of SFAS 123R. For share-based awards issued to employees and directors, share-based compensation is attributed to expense using the straight-line single option method. Share-based compensation expense recognized in our consolidated statements of operations for the three months ended September 30, 2010 and 2009 is based on awards ultimately expected to vest, reduced for estimated forfeitures. Accounting rules for stock options require forfeitures to be estimated at the time of grant and revised, if necessary, in subsequent periods if actual forfeitures differ from those estimates.

During the three and nine months ended September 30, 2010 and 2009, we granted options to employees for  400,000, 400,000,0,497,000 shares, respectively, at the weighted average per share exercise price of $0.11, $0.11, $0.00, $0.30  respectively, the fair market value of our common stock at the dates of grants. Approximately 271,700

10

of the options granted in 2009 vested immediately on the date of grant. Employee and director stock option activity for the three and nine months ended September 30, 2010, included cancellations only and was as follows:

				Weighted Avg.
	Shares			Exercise Price
Balance December 31, 2009		10,913,000		$	2.16
Three months ended March 31, 2010
Cancelled		(365,000	)		0.93
Balance March 31, 2010		10,548,000		$	2.20
Three months ended June 30, 2010
Cancelled		(886,000	)		2.70
Balance June 30, 2010		9,662,000		$	2.15
Three months ended September 30, 2010
Granted		400,000			0.11
Cancelled		(571,000	)		3.47
Balance September 30, 2010		9,491,000		$	1.99

The estimated fair value of options granted to employees during the three and nine months ended September 30, 2010 was $31,000 and $31,000 respectively, calculated using the Black-Scholes pricing model with the following assumptions:

	Three Months Ended		Nine Months Ended
	September 30,		September 30,
	2010	2009	2010	2009
Expected volatility	82%	72%	82%	72%
Risk-free interest rate	1.76%	2.27-2.37%	1.76%	2.27-2.37%
Weighted average expected lives in years	5.0-6.0	5.0-6.0	5.0-6.0	5.0-6.0
Expected dividend	0%	0%	0%	0%

The expected volatility assumptions have been based on the historical and expected volatility of our stock, measured over a period generally commensurate with the expected term. The weighted average expected option term for the three months ended September 30, 2010 reflects the application of the simplified method prescribed in SEC Staff Accounting Bulletin (SAB) No. 107 (and as amended by SAB 110), which defines the life as the average of the contractual term of the options and the weighted average vesting period for all option tranches.

As of September 30, 2010, there was $3 million of total unrecognized compensation costs related to non-vested share-based compensation arrangements granted under the Plan. That cost is expected to be recognized over a weighted-average period of approximately 2.5 years

Stock Options and Warrants – Non-employees

We account for the issuance of options and warrants for services from non-employees by estimating the fair value of warrants issued using the Black-Scholes pricing model. This model’s calculations include the option or warrant exercise price, the market price of shares on grant date, the weighted average risk-free interest rate, expected life of the option or warrant, expected volatility of our stock and expected dividends.

For options and warrants issued as compensation to non-employees for services that are fully vested and non-forfeitable at the time of issuance, the estimated value is recorded in equity and expensed when the services are performed and benefit is received. For unvested shares, the change in fair value during the period is recognized in expense using the graded vesting method.

11

There were no options granted and no share-based expense attributable to continuing operations relating to stock options and warrants granted to non-employees during the three and nine months ended September 30, 2010. For the same periods in 2009 we granted options for 0 and 60,000 shares at the weighted average per share exercise price of $0.00 and $0.52, the fair market value of our common stock at the dates of grants. For the three and nine months ended September 30, 2010 and 2009, share-based expense attributable to continuing operations relating to stock options and warrants granted to non-employees was $0, $6,000, $43,000 and $67,000, respectively.

Non-employee stock option and warrant activity for the three and nine months ended September 30, 2010 was as follows:

As of September 30, 2010				Weighted Avg.
	Shares			Exercise Price
Balance December 31, 2009		1,690,000		$	3.57
Balance March 31, 2010		1,690,000		$	3.57
Cancelled		(105,000	)		2.60
Balance June 30, 2010		1,585,000		$	3.63
Cancelled		(48,000	)		2.60
Balance September  30, 2010		1,537,000		$	3.67

Common Stock

During the three and nine months ended September 30, 2010 and 2009, we issued 10 million, 16.1 million , 600,000 and 789,000 shares of common stock, respectively, related to the July, 2010, $2 million registered direct financing and in exchange for various services and settlement of claims.  The costs associated with shares issued for services are being amortized to share-based expense on a straight-line basis over the related nine month to one year service periods. For the three and nine months ended September 30, 2010 and 2009, share-based expense relating to all common stock issued for consulting services was $25,000 and $401,000 compared to $52,000 and $227,000, respectively. The cost of the shares issued in settlement of claims in the amount of $1.2 million, due for services provided to us which had not been paid were recognized in prior periods. The court approved the settlements of complaints against us in California state court in exchange for issuing 445,000 shares of common stock in January 2010 and 5,000,000 shares of our common stock in April 2010 pursuant to Section 3(a)(10) of the Securities Act of 1933 as amended. The April settlement is subject to adjustment 180 days subsequent to the issuance of the shares and the owner of the claim will not sell more than the greater of 49,000 shares or 10% of the daily trading volume per the terms of the settlement.

Employee Stock Purchase Plan

We have a qualified employee stock purchase plan (ESPP), approved by our stockholders, which allows qualified employees to participate in the purchase of designated shares of our common stock at a price equal to 85% of the lower of the closing price at the beginning or end of each specified stock purchase period. There were no shares of our common stock issued pursuant to the ESPP and, thus, no expense incurred during the nine months ended September 30, 2010. For the same period in 2009, we issued 8,928 shares of common stock and incurred no expense related to the ESPP discount price.

Income Taxes

We account for income taxes using the liability method in accordance with current FASB income tax accounting rules. To date, no current income tax liability has been recorded due to our accumulated net losses. Deferred tax assets and liabilities are recognized for temporary differences between the financial statement carrying amount of assets and liabilities and the amounts that are reported in the tax return. Deferred tax assets and liabilities

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are recorded on a net basis; however, our net deferred tax assets have been fully reserved by a valuation allowance due to the uncertainty of our ability to realize future taxable income and to recover our net deferred tax assets.

We recognize the impact of tax positions in the consolidated financial statements if that position is more likely than not of being sustained on audit, based on the technical merits of the position. To date, we have not identified any uncertain tax positions.

Costs associated with streamlining our operations

During the three and nine months ended September 30, 2010 and 2009, we continued to streamline our operations to increase our focus on managed care opportunities and reposition ourselves to be more competitive in the marketplace. We did not record any costs related to streamlining our operations in 2010 compared to $1,000 and $1.2 million of such costs in the three and nine months ended 2009, respectively.

Marketable Securities

At September 30, 2010, investments include certificates of deposit with maturity dates greater than three months when purchased compared to ARS and certificates of deposit at December 31, 2009. These investments are classified as available-for-sale investments, are reflected in current assets as marketable securities and are stated at fair market value in accordance with FASB accounting rules related to investment in debt securities. Unrealized gains and losses are reported in our Consolidated Balance Sheet within the caption entitled “Accumulated other comprehensive income (loss)” and within Comprehensive Income (Loss) under the caption “other comprehensive income (loss).” Realized gains and losses and declines in value judged to be other-than-temporary are recognized as an impairment charge in the statement of operations on the specific identification method in the period in which they occur.

In making our determination whether losses are considered to be other-than-temporary declines in value, we consider the following factors at each quarter-end reporting period:

●   How long and by how much the fair value of the ARS securities have been below cost;

●   The financial condition of the issuers;

●   Any downgrades of the securities by rating agencies;

●   Default on interest or other terms; and

●   Whether it is more likely than not that we will be required to sell the ARS before they recover in value.

In accordance with current accounting rules for investments in debt securities and additional application guidance issued by the FASB in April 2009, other-than-temporary declines in value are reflected as a non-operating expense in our consolidated statement of operations if it is more likely than not that we will be required to sell the ARS before they recover in value, whereas subsequent increases in value are reflected as unrealized gains in accumulated other comprehensive income in stockholders’ equity in our consolidated balance sheet.

Our marketable securities consisted of investments with the following maturities as of September 30, 2010 and December 31, 2009:

(in thousands)	Fair Market		Less than		More than
	Value		1 Year		10 Years
Balance at December 31, 2009
Certificates of deposit	$	133	$	133	$	-
Auction-rate securities		9,468		9,468		-
Balance at September 30, 2010
Certificates of deposit	$	133	$	133	$	-

The carrying value of all securities presented above approximated fair market value at September 30, 2010 and December 31, 2009.

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Auction-Rate Securities

Since February 2008, auctions for these securities had failed; meaning the parties desiring to sell securities could not be matched with an adequate number of buyers, resulting in our having to continue to hold these securities. Although the securities are Aaa/AAA rated and collateralized by portfolios of student loans guaranteed by the U.S. government, based on current market conditions it is likely that auctions will continue to be unsuccessful in the short-term, limiting the liquidity of these investments until the issuer calls the securities. The maturity dates of the underlying securities of our ARS investments ranged from 18 to 37 years.  In October 2008, our portfolio manager, UBS AG (UBS) made a rights offering to its clients, pursuant to which we are entitled to sell to UBS all ARS held by us in our UBS account. We subscribed to the rights offering in November 2008, which permitted us to require UBS to purchase our ARS for a price equal to original par value plus any accrued but unpaid interest beginning on September 30, 2010 and ending on July 2, 2012, if the securities were not earlier redeemed or sold. During the nine months ended June 30, 2010, $10.2 million (par value) of ARS were redeemed at par by the issuer.

 The rights offering referred to above was effectively a put option agreement. Consequently, we recognized the put option agreement as a separate asset in the amount of approximately $758,000 in accordance with FASB accounting rules and it is included at fair market value in other current assets in our consolidated balance sheet at December 31, 2009. As the ARS were redeemed at par value we determined that the fair market value of the ARS at June 30, 2010 was the redemption amount, and as a result have written down the value of the put option to zero at June 30, 2010.  The related $758,000 reduction in the value of the put option is reflected as a charge to gain on sale of marketable securities in our consolidated income statement for the nine months ended September 30, 2010.

Fair Value Measurements

Fair value is defined as the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction between market participants at the measurement date. Assets and liabilities recorded at fair value in the consolidated balance sheets are categorized based upon the level of judgment associated with the inputs use to measure fair value. The fair value hierarchy distinguishes between (1) market participant assumptions developed based on market data obtained from independent sources observable inputs and (2) an entity’s own assumptions about market participant assumptions developed based on the best information available in the circumstances (unobservable outputs). The fair value hierarchy consists of three broad levels, which gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1) and the lowest priority to unobservable inputs (Level 3). The three levels of the fair value hierarchy are described below:

Level Input:	Input Definition:
Level I	Inputs are unadjusted, quoted prices for identical assets or liabilities in active markets at the measurement date.
Level II	Inputs, other than quoted prices included in Level I, that are observable for the asset or liability through corroboration with market data at the measurement date.
Level III	Unobservable inputs that reflect management’s best estimate of what market participants would use in pricing the asset or liability at the measurement date.

The following table summarizes fair value measurements by level at September 30, 2010 for assets and liabilities measured at fair value on a recurring basis:

(Dollars in thousands)	Level I		Level II		Level III		Total
Certificates of deposit (1)		133		-		-		133
Total assets		133		-		-		133
Warrant liabilities		-		-		72		72
Total liabilities		-		-		72		72
(1) included in deposits and other assets on our consolidated balance sheets

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Liabilities measured at market value on a recurring basis at September 30, 2010 and December 31, 2009 includes warrant liabilities resulting from debt and equity financing. In accordance with current accounting rules, the warrant liabilities are being marked to market each quarter-end until they are completely settled. The warrants are valued using the Black-Scholes method, using both observable and unobservable inputs and assumptions consistent with those used in our estimate of fair value of employee stock options. See Warrant Liabilities below.

The following table summarizes our fair value measurements by level at December 31, 2009, and changes therein, for the nine months ended September 30, 2010:

	Level III			Level III
	ARS			Warrant
(Dollars in thousands)	& Put			Liabilities
Balance as of December 31, 2009	$	10,225		$	1,089
Transfers in/(out) of Level III		-			-
Change in Fair Value		-			(657	)
Net purchases (sales)		(250	)		-
Net unrealized gains (losses)		(30	)		-
Net realized gains (losses)		30			-
Balance as of March 31, 2010	$	9,975		$	432
Transfers in/(out) of Level III		(2,225	)		-
Change in Fair Value		-			(237	)
Net purchases (sales)		(7,750	)		-
Net unrealized gains (losses)		(693	)		-
Net realized gains (losses)		693			-
Balance as of June 30, 2010	$	-		$	195
Transfers in/(out) of Level III		-			790
Change in Fair Value		-			(913	)
Net purchases (sales)		-			-
Net unrealized gains (losses)		-			-
Net realized gains (losses)		-			-
Balance as of September 30, 2010	$	-		$	72

As discussed above, there have been continued auction failures with our ARS portfolio and as a result, active markets for our ARS did not exist and we relied primarily on Level III inputs, for fair valuation measures as of December 31, 2009. On July 2, 2010, upon trade settlement, we collected the $2.2 million receivable related to the sale of the remainder of our ARS portfolio As of September 30, 2010, our ARS Portfolio was fully liquidated at par.

Intangible Assets

As of September 30, 2010, the gross and net carrying amounts of intangible assets that are subject to amortization are as follows:

	Gross							Amortization
(In thousands)	Carrying		Accumulated			Net		Period
	Amount		Amortization			Balance		(in years)
Intellectual property	$	4,361	$	(1,879	)	$	2,482		11-16

During the nine months ended September 30, 2010, we did not acquire any new intangible assets and at September 30, 2010, all of our intangible assets consisted of intellectual property, which is not subject to renewal or extension. We performed impairment tests on intellectual property as of September 30, 2010 and after considering numerous factors, we determined that the carrying value of certain intangible assets was recoverable as of September 30, 2010.  During the nine months ended September 30, 2010 we did not record impairment charges

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associated with our intellectual property. At December 31, 2009, we had an independent third-party perform a valuation of our intellectual property. They relied on the “relief from royalty” method, as this method was deemed to be most relevant to the intellectual property assets of the Company.  We determined that the estimated useful lives of the remaining intellectual property properly reflected the current remaining economic useful lives of the assets.

Estimated remaining amortization expense for intangible assets for the current year and each of the next five years ending December 31 is as follows:

(In thousands)
Year	Amount
2010	$       177
2011	$       241
2012	$       241
2013	$       241
2014	$       241

Property and Equipment

Property and equipment are stated at cost, less accumulated depreciation. Additions and improvements to property and equipment are capitalized at cost. Expenditures for maintenance and repairs are charged to expense as incurred. Depreciation is computed using the straight-line method over the estimated useful lives of the related assets, which range from two to seven years for furniture and equipment. Leasehold improvements are amortized over the lesser of the estimated useful lives of the assets or the related lease term, which is typically five to seven years.

Variable Interest Entities

Generally, an entity is defined as a Variable Interest Entity (VIE) if it has (a) equity that is insufficient to permit the entity to finance its activities without additional subordinated financial support from other parties, or (b) equity investors that cannot make significant decisions about the entity’s operations, or that do not absorb the expected losses or receive the expected returns of the entity. When determining whether an entity that is a business qualifies as a VIE, we also consider whether (i) we participated significantly in the design of the entity, (ii) we provided more than half of the total financial support to the entity, and (iii) substantially all of the activities of the VIE either involve us or are conducted on our behalf. A VIE is consolidated by its primary beneficiary, which is the party that absorbs or receives a majority of the entity’s expected losses or expected residual returns.

As discussed under the heading Management Services Agreements below, we have a MSA with a managed medical corporation. Under this MSA, the equity owner of the affiliated medical group has only a nominal equity investment at risk, and we absorb or receive a majority of the entity’s expected losses or expected residual returns. We participate significantly in the design of this MSA. We also agree to provide working capital loans to allow for the medical group to pay for its obligations. Substantially all of the activities of this managed medical corporation either involve us or are conducted for our benefit, as evidenced by the facts that (i) the operations of the managed medical corporations are conducted primarily using our licensed protocols and (ii) under the MSA, we agree to provide and perform all non-medical management and administrative services for the respective medical group. Payment of our management fee is subordinate to payments of the obligations of the medical group, and repayment of the working capital loans is not guaranteed by the equity owner of the affiliated medical group or other third party. Creditors of the managed medical corporations do not have recourse to our general credit.

Based on the design and provisions of this MSA and the working capital loans provided to the medical group, we have determined that the managed medical corporation is a VIE, and that we are the primary beneficiary as defined in the current accounting rules. Accordingly, we are required to consolidate the revenues and expenses of the managed medical corporation.

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Management Services Agreements

We have executed MSAs with medical professional corporations and related treatment centers, with terms generally ranging from five to ten yearsand provisions to continue on a month-to-month basis following the initial term, unless terminated for cause. In May 2009, we terminated the MSAs with a medical professional corporation and a managed treatment center located in Dallas, Texas “for cause” and because the Company had fully met its funding requirements with respect to the MSAs. As a result, we no longer consolidate these entities as VIEs.

Under the remaining MSA, we license to the treatment center the right to use our proprietary treatment programs and related trademarks and provide all required day-to-day business management services, including, but not limited to:

●   general administrative support services;

●   information systems;

●   recordkeeping;

●   scheduling;

●   billing and collection;

●   marketing and local business development; and

●   obtaining and maintaining all federal, state and local licenses, certifications and regulatory permits.

The treatment center retains the sole right and obligation to provide medical services to its patients and to make other medically related decisions, such as the choice of medical professionals to hire or medical equipment to acquire and the ordering of drugs.

In addition, we provide medical office space to the treatment center on a non-exclusive basis, and we are responsible for all costs associated with rent and utilities. The treatment center pays us a monthly fee equal to the aggregate amount of (a) our costs of providing management services (including reasonable overhead allocable to the delivery of our services and including start-up costs such as pre-operating salaries, rent, equipment, and tenant improvements incurred for the benefit of the medical group, provided that any capitalized costs will be amortized over a five year period), (b) 10%-15% of the foregoing costs, and (c) any performance bonus amount, as determined by the treatment center at its sole discretion. The treatment center’s payment of our fee is subordinate to payment of the treatment center's obligations, including physician fees and medical group employee compensation.

We have also agreed to provide a credit facility to treatment center to be available as a working capital loan, with interest at the Prime Rate plus 2%. Funds are advanced pursuant to the terms of the MSAs described above.  The notes are due on demand or upon termination of the respective MSA. At September 30, 2010, there was one outstanding credit facility under which $10.2 million was outstanding. Our maximum exposure to loss could exceed this amount, and cannot be quantified as it is contingent upon the amount of losses incurred by the respective treatment center that we are required to fund under the credit facility.

Under the MSA, the equity owner of the affiliated treatment center has only a nominal equity investment at risk, and we absorb or receive a majority of the entity’s expected losses or expected residual returns. We participate significantly in the design of the MSA. We also agree to provide working capital loans to allow for the treatment center to pay for its obligations. Substantially all of the activities of these managed medical corporations either involve us or are conducted for our benefit, as evidenced by the facts that (i) the operations of the managed medical corporations are conducted primarily using our licensed protocols and (ii) under the MSA, we agree to provide and perform all non-medical management and administrative services for the respective treatment center. Payment of our management fee is subordinate to payments of the obligations of the treatment center, and repayment of the working capital loans is not guaranteed by the equity owner of the affiliated treatment center or other third party. Creditors of the managed medical corporations do not have recourse to our general credit. Based on these facts, we have determined that the managed medical corporations are VIEs and that we are the primary beneficiary as defined in current accounting rules.  Accordingly, we are required to consolidate the assets, liabilities, revenues and expenses of the managed treatment centers.

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The amounts and classification of assets and liabilities of the VIEs included in our Consolidated Balance Sheets at September 30, 2010 and December 31, 2009 are as follows:

	September 30,		December 31,
(in thousands)	2010		2009
Cash and cash equivalents	$	48		23
Receivables, net		1		-
Total assets	$	49		23
Accounts payable		19		14
Note payable *		10,192		9,214
Accrued liabilities		13		6
Total liabilities	$	10,224		9,234
* Eliminated during consolidation

Warrant Liabilities

We had issued warrants in connection with the registered direct placement of our common stock in November 2007, September 2009 and the amended and restated Highbridge senior secured note in July 2008. In July 2010, Hythiam, Inc. entered a into securities purchase agreements with several institutional investors (the “Investors”) relating to the sale and issuance by the Company to the Investors of $ 2,000,000 of shares of the Company’s common stock and warrants (the “Warrants”) to purchase shares (the “Warrant Shares”) of the Company’s common stock.  Each share of common stock was sold at a price of $0.20 per share.  Investors will received Warrants to purchase three shares of common stock at an exercise price of $0.20 per share for every four shares of common stock they purchase in this offering. Total shares issued were 10 million and 7,500,000 warrants valued at $790,000 fair market value based on the Black Scholes calculation.

The warrants include provisions that require us to record them at fair value as a liability in accordance with EITF 00-19, with subsequent changes in fair value recorded as a non-operating gain or loss in our statement of operations. The fair value of the warrants is determined using a Black-Scholes option pricing model, and is affected by changes in inputs to that model including our stock price, expected stock price volatility, interest rates and expected term.

For the three and nine months ended September 30, 2010 and 2009, we recognized non-operating gains/(losses) of $913,000 and $1.8 million compared to ($4.8) million and ($4.7) million, respectively, related to the revaluation of our warrant liabilities. We will continue to re-measure the warrant liabilities at fair value each quarter-end until they are completely settled or expire.

Recent Accounting Pronouncements

Recently Adopted

In February 2010, the FASB issued ASU 2010-09, “Subsequent Events, Amendments to Certain Recognition and Disclosure Requirements” which made a number of changes to the existing requirements to the FASB Accounting Standards Codification 855 Subsequent Events. The amended guidance was effective upon issuance and as a result of the amendments, SEC filers that file financial statements after February 24, 2010 are not required to disclose the date through which subsequent events have been evaluated. This ASU was adopted as of September 30, 2010 and did not have a material impact on our consolidated financial statements.

In January 2010, the FASB issued ASU 2010-06, “Fair Value Measurements and Disclosures: Improving Disclosures about Fair Value Measurements” which is intended to enhance the usefulness of fair value measurements by requiring both the disaggregation of the information in certain existing disclosures, as well as the inclusion of more robust disclosures about valuation techniques and inputs to recurring and non-recurring fair value measurements. The amended guidance is effective for interim and annual reporting periods beginning after December 15, 2009, except for the disaggregation requirement for the reconciliation disclosure of Level 3

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measurements, which is effective for fiscal years beginning after December 31, 2010 and for interim periods within those years. This ASU was adopted as of September 30, 2010 and did not have a material impact on our consolidated financial statements.

In January 2010, the FASB issued ASU 2010-02, “Accounting and Reporting for Decreases in Ownership of a Subsidiary – Scope Clarification” which is intended to clarify which transactions require a decrease in ownership provisions particularly for non-controlling interests in consolidated financial statements. In addition, it requires increased disclosures about deconsolidation of a subsidiary. It requires retrospective application and is effective for the first interim or annual periods ending on or after December 15, 2009. Adoption of this ASU will not have a material impact on our consolidated financial statements.

In January 2010, the FASB issued ASU 2020-01 “Accounting for Distributions to Shareholders with Components of Stock and Cash” which is intended to clarify the accounting treatment for a stock portion of a shareholder distribution that (1) contains both cash and stock components, (2) allows shareholders to select their preferred form of distribution, and (3) limits the total amount of cash to be distributed. It defines a stock dividend as a dividend that takes nothing from the property of an entity and adds nothing to the interests of an entity’s shareholders because the proportional interest of each shareholder remains the same. The stock portion of the distribution must be treated as a stock issuance and be reflected in the EPS calculation prospectively. It requires retrospective application and is effective for annual periods ending on or after December 15, 2009. Adoption of this ASU will not have a material impact on our consolidated financial statements.

In August 2009, the FASB issued ASU 2009-15, which changes the fair value accounting for liabilities. These changes clarify existing guidance that in circumstances in which a quoted price in an active market for the identical liability is not available, an entity is required to measure fair value using either a valuation technique that uses a quoted price of either a similar liability or a quoted price of an identical or similar liability when traded as an asset, or another valuation technique that is consistent with the principles of fair value measurements, such as an income approach (e.g., present value technique). This guidance also states that both a quoted price in an active market for the identical liability and a quoted price for the identical liability when traded as an asset in an active market when no adjustments to the quoted price of the asset are required are Level 1 fair value measurements. This ASU was adopted effective on January 1, 2010 and did not have a material impact on our consolidated financial statements.

In June 2009, the FASB issued ASU 2009-17, “Improvements to Financial Reporting by Enterprises Involved with Variable Interest Entities,” the FASB issued changes to the accounting for variable interest entities. These changes require an enterprise to perform an analysis to determine whether the enterprise’s variable interest or interests give it a controlling financial interest in a variable interest entity; to require ongoing reassessments of whether an enterprise is the primary beneficiary of a variable interest entity; to eliminate the quantitative approach previously required for determining the primary beneficiary of a variable interest entity; to add an additional reconsideration event for determining whether an entity is a variable interest entity when any changes in facts and circumstances occur such that holders of the equity investment at risk, as a group, lose the power from voting rights or similar rights of those investments to direct the activities of the entity that most significantly impact the entity’s economic performance; and to require enhanced disclosures that will provide users of financial statements with more transparent information about an enterprise’s involvement in a variable interest entity. These changes became effective for us beginning on January 1, 2010. The adoption of this change did not have a material impact on our consolidated financial statements.

In June 2009, the FASB issued ASU 2009-16, “Accounting for Transfers of Financial Assets,” which changes the accounting for transfers of financial assets. These changes remove the concept of a qualifying special-purpose entity and remove the exception from the application of variable interest accounting to variable interest entities that are qualifying special-purpose entities; limits the circumstances in which a transferor derecognizes a portion or component of a financial asset; defines a participating interest; requires a transferor to recognize and initially measure at fair value all assets obtained and liabilities incurred as a result of a transfer accounted for as a sale; and requires enhanced disclosure; among others. These changes became effective January 1, 2010 and did not have a material impact on our financial statements.

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Recently Issued

The following Accounting Standards Updates were issued between December 2009 and September 30, 2010 and contain amendments and technical corrections to certain SEC references in FASB's codification:

In April 2010, the FASB issued ASU 2010-13, “Share-based payment awards denominated in certain currencies” provides clarification on an employee share-based payment award that has an exercise price denominated in the currency of the market in which a substantial portion of the entity’s equity shares trades should not be considered to contain a condition that is not a market, performance, or service condition. Therefore, an entity should not classify such an award as a liability if it otherwise qualifies as equity. The amended guidance is effective for fiscal years, and interim periods within those fiscal years, beginning on or after December 15, 2010. The Company expects to adopt the amended guidance on January 1, 2011. The Company does not believe that the adoption of the amended guidance will have a significant effect on its consolidated financial statements.

In April 2010, the FASB issued ASU 2010-17, “Milestone Method of Revenue Recognition” guidance to address accounting for research or development arrangements in which a vendor satisfies its performance obligations over time, with all or a portion of the consideration contingent on future events, referred to as milestones. The new guidance allows a vendor to adopt an accounting policy to recognize all of the arrangement consideration that is contingent on the achievement of a milestone in the period the milestone is achieved, if the milestone meets the criteria to be considered a substantive milestone. The milestone method described in the new guidance is not the only acceptable revenue attribution model for milestone consideration. However, other methods that result in the recognition of all of the milestone consideration in the period the milestone is achieved are precluded. A vendor is not precluded from electing to apply a policy that results in the deferral of some portion of the milestone consideration. The new guidance is effective on a prospective basis for milestones achieved in fiscal years, and interim periods within those fiscal years, beginning on or after June 15, 2010, with early adoption permitted. If an entity early adopts in a period that is not the beginning of its fiscal year, it must apply the guidance retrospectively from the beginning of the year of adoption. A vendor may elect to adopt the new guidance retrospectively for all prior periods, but is not required to do so. The Company is still evaluating the effect, if any; the amended guidance may have on its consolidated financial statements.

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Note 3.   Segment Information

We manage and report our operations through two business segments: Behavioral Health and Healthcare Services. During the three months ended March 31, 2009, we revised our segments to reflect the disposal of CompCare (see Note 5 Discontinued Operations), and to properly reflect how our segments are currently managed. Our behavioral health managed care services segment, which had been comprised entirely of the operations of CompCare, is now presented in discontinued operations and is not a reportable segment. The Healthcare Services segment has been segregated into Behavioral Health and Healthcare Services.

We evaluate segment performance based on total assets, revenue and income or loss before provision for income taxes. Our assets are included within each discrete reporting segment. In the event that any services are provided to one reporting segment by the other, the transactions are valued at the market price. No such services were provided during the three and nine months ended September 30,2010 and 2009. Summary financial information for our two reportable segments is as follows:

	Three Months Ended						Nine Months Ended
(in thousands)	September 30,						September 30,
	2010			2009			2010			2009
Healthcare services
Revenues	$	95		$	268		$	319		$	1,346
Loss before provision for income taxes		(1,333	)		(7,978	)		(5,764	)		(17,963	)
Assets *		3,482			20,834			3,482			20,834
Behavioral health
Revenues	$	9		$	-		$	19		$	-
Loss before provision for income taxes		(575	)		(861	)		(1,750	)		(3,187	)
Assets *		-			-			-			-
Consolidated continuing operations
Revenues	$	104		$	268		$	338		$	1,346
Loss before provision for income taxes		(1,908	)		(8,839	)		(7,514	)		(21,150	)
Assets *		3,482			20,834			3,482			20,834
* Assets are reported as of September 30.

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Behavioral Health

Catasys’s integrated substance dependence solution combines innovative medical and psychosocial treatments with elements of traditional disease management and ongoing member support to help organizations treat and manage substance dependent populations to impact both the medical and behavioral health costs associated with substance dependence and the related co-morbidities.

We are currently marketing our Catasys integrated substance dependence solutions to managed care health plans for reimbursement on a case rate or monthly fee, which involves educating third party payors on the disproportionately high cost of their substance dependent population and demonstrating the potential for improved clinical outcomes and reduced cost associated with using our Catasys programs.

The following table summarizes the operating results for Behavioral Health for the three and nine months ended September 30, 2010 and 2009:

	Three Months Ended						Nine Months Ended
(in thousands)	September 30,						September 30,
	2010			2009			2010			2009
Revenues	$	9		$	-		$	19		$	-
Operating Expenses
General and administrative expenses
Salaries and benefits	$	529		$	773		$	1,650		$	1,983
Other expenses		55			88			119			363
Impairment charges		-			-			-			758
Depreciation and amortization		-			-			-			83
Total operating expenses	$	584		$	861		$	1,769		$	3,187
Loss before provision for income taxes	$	(575	)	$	(861	)	$	(1,750	)	$	(3,187	)

Healthcare Services

Our Healthcare Services segment is focused on delivering solutions for those suffering from alcohol, cocaine, methamphetamine and other substance dependencies by researching, developing, licensing and commercializing innovative physiological, nutritional, and behavioral treatment programs. Treatment with our PROMETA Treatment Programs, which integrate behavioral, nutritional, and medical components, are available through physicians and other licensed treatment providers who have entered into licensing agreements with us for the use of our treatment programs. Also included in this segment are licensed and managed treatment centers, which offer a range of addiction treatment and mental health services, including the PROMETA Treatment Programs for dependencies on alcohol, cocaine and methamphetamines.

Our healthcare services segment also comprises international operations; however, these operating segments are not separately reported as they do not meet any of the quantitative thresholds under SFAS No. 131, Disclosures about Segments of an Enterprise and Related Information.

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The following table summarizes the operating results for Healthcare Services for the three and nine months ended September, 2010 and 2009:

(In thousands, except patient treatment data)		Three months ended						Nine months ended
		September 30,						September 30,
		2010			2009			2010			2009
Revenues
	U.S. licensees	$	30		$	123		$	106		$	459
	Managed treatment centers		65			145			213			753
	Other revenues		-			-			-			134
	Total healthcare services revenues	$	95		$	268		$	319		$	1,346
Operating expenses
	Cost of healthcare services	$	99		$	68		$	174		$	502
	General and administrative expenses
	Salaries and benefits		1,595			899			5,243			5,285
	Other expenses		402			2,118			2,242			6,376
	Research and development		-			-			-			-
	Impairment losses		1			-			39			355
	Depreciation and amortization		204			273			705			896
	Total operating expenses	$	2,301		$	3,358		$	8,403		$	13,414
Loss from operations		$	(2,206	)	$	(3,090	)	$	(8,084	)	$	(12,068	)
	Interest and other income		1			19			129			142
	Interest expense		(41	)		(221	)		(312	)		(999	)
	Loss on extinguishment of debt		-			(54	)		-			(330	)
	Gain on the sale of marketable securities		-			160			696			160
	Other than temporary impairment on
	marketable securities		-			(25	)		-			(185	)
	Change in fair value of warrant liabilities		913			(4,767	)		1,807			(4,683	)
Loss before provision for income taxes		$	(1,333	)	$	(7,978	)	$	(5,764	)	$	(17,963	)
PROMETA patients treated
	U.S. licensees		6			24			24			96
	Managed treatment centers		7			22			21			78
	Other		-			-			-			11
			13			46			45			185
Average revenue per patient treated (a)
	U.S. licensees	$	5,017		$	4,435		$	4,398		$	4,298
	Managed treatment centers		2,972			4,206			3,213			5,957
	Other		-			-			-			12,185
	Overall average		3,916			4,326			3,845			5,466
(a)	The average revenue per patient treated excludes administrative fees and other non-PROMETA patient revenues.

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Note 4.   Debt Outstanding

The following table shows the total principal amount, related interest rates and maturities of debt outstanding, as of  September 30, 2010 and December 31, 2009:

	September 30		December 31,
(dollars in thousands, except where otherwise noted)	2010		2009
Short-term debt
Senior secured note due July 15, 2010; interest payable quarterly at prime
plus 2.5% (5.75% at December 31, 2009). $3,332,000 principal net of $147,000
unamortized discount at December 31, 2009.
Debt fully eliminated in July 2010	$	-	$	3,185
UBS line of credit, payable on demand, interest payable monthly at 90-day
T-bill rate plus 120 basis points 1.237% at December 31, 2009
Debt fully eliminated in July 2010		-		6,458
Total Short-term debt	$	-	$	9,643

During the second quarter we sold $10.2 million of par value ARS and settled $8 million with the balance of $2.2 million settling on July 2, 2010. We drew down $450,000 on the UBS line of credit and paid our debt of $6.9 million in full according to the terms and conditions of our line of credit. On July 15, 2010, our senior secured note in the amount of $3.3 million matured and we paid from available funds.

Note 5.   Discontinued Operations

On January 20, 2009, we sold our interest in CompCare, in which we had acquired a controlling interest in January 2007 for $1.5 million in cash. The CompCare operations are now presented as discontinued operations in accordance with accounting rules related to the disposal of long-lived assets. Prior to the sale, the assets, and results of operations related to CompCare had constituted our behavioral health managed care services segment. See Note 3 Segment Information for an updated discussion of our business segments after the sale of CompCare.

We recognized a gain of approximately $11.2 million from this sale, which is included in income from discontinued operations in our Consolidated Statement of Operations for the three months ended March 31, 2009. The revenues and expenses of discontinued operations for the period January 1 through January 20, 2009 are as follows:

	Period from
	January 1 to
	January 20,
(in thousands)	2009
Revenues:
Behavioral managed health care revenues	$	710
Expenses:
Behavioral managed health care operating expenses	$	703
General and administrative expenses		711
Other		50
Income (loss) from discontinued operations before
provision for income tax	$	(754	)
Provision for income taxes	$	1
Income (loss) from discontinued operations, net of tax	$	(755	)
Gain on sale	$	11,204
Results from discontinued operations, net of tax	$	10,449

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Note 6.   Commitments and Contingencies

		Less than	1 - 3	3 - 5	More than
Contractual Commitments	Total	1 year	years	years	5 years
Outstanding Debt Obligations	$             -	$             -
Capital Lease  Obligations	73	65	8	-	-
Operating Lease Obligations	355	340	15	-	-
Clinical Studies	356	356	-	-	-
Total	$          784	$          761	$          23	$           -	$             -

In May 2010, we entered into an amendment to one of our operating leases which resulted in the deferral of rents of approximately $124,000 with $57,000 remaining at the end of the third quarter of 2010.

In August 2006, the Company entered into a 5 year lease agreement for approximately 4,000 square feet of medical space for a company managed treatment center in San Francisco, CA. The Company ceased operations at the center in January 2008. In the first quarter of 2009, the Company ceased making rent payments under the lease. In November of 2009, the landlord filed a lawsuit against the Company seeking damages of at least $350,000, plus attorney fees and costs. On March 23, 2010 the Company settled this lawsuit for $200,000 to be paid in monthly installments from March 23, 2010 to February 2011, with $35,000 remaining at the end of the third quarter.

Note 7.   Subsequent Events

In October 2010, the Company entered into Securities Purchase Agreements with certain accredited investors, including Socius Capital Group, LLC, an affiliate of our Chairman and CEO, for $500,000 of senior 12% secured convertible notes (the “Bridge Notes”) and warrants to purchase 12,500,000 shares of our common stock (the “Bridge Warrants”).

The Bridge Notes were scheduled to mature January 2011 and interest was payable in cash at maturity or upon prepayment or conversion.  The Bridge Notes and any accrued interest were convertible at the holders’ option into common stock or exchangeable for the securities issued in the next financing the Company entered into that results in gross proceeds to the Company of at least $3,000,000.  The Bridge Warrants were exercisable for 5 years at $.04 per share subject to adjustment for financings and share issuances below the initial exercise price. The Bridge Warrants for the non-affiliated investors limit the amount of common stock that the holders may acquire through an exercise to no more than 4.99% of all Company Securities, defined as common stock, voting stock, or other Company securities. All the holders exchanged the Bridge Notes plus interest for securities issued in the Company’s November 2010 financing (see below).

In November 2010, the Company completed a private placement with certain accredited investors, including Socius Capital Group, LLC, an affiliate of our Chairman and CEO, and one other Hythiam director, for gross proceeds of $6.9 million (the “Offering”). Of the gross proceeds, $503,000 represented the exchange of the Bridge Notes and accrued interest and $215,000 represented the cancellation of an accrued compensation liability to our Chairman and CEO. The Company incurred approximately $364,000 in financial advisory, legal and other fees in relation to the offering. In addition, the Company issued warrants to purchase 5,670,000 shares of common stock at $.01 per share to the financial advisors. The Company issued 100,000,000 shares of common stock (“Shares”) at a price of $.01 per share and $5.9 million in aggregate principal of 12% senior secured convertible notes (the “Notes”) to the investors on a pro rata basis. The Notes mature on the second anniversary of the closing.  Interest is payable in cash at maturity or upon prepayment. The Notes are secured by a first priority security interest in all of the Company’s assets. The Notes and any accrued interest convert automatically into common stock if and when sufficient shares become authorized at a conversion price of $.01 per share, subject to certain adjustments, including certain share issuances below $.01 per share. The Company agreed to use its best efforts to file a proxy statement seeking shareholder approval to increase the number of authorized shares within 30 days of closing. In addition, each investor investing $2,000,000 or more also received 5-year warrants to purchase an aggregate of 21,960,000 shares of Company common stock at an exercise price of $.01 per share. One non-affiliated investor received such warrants. The net cash proceeds to the Company from the Offering are estimated to be $6.4 million inclusive of the October transaction and after offering expenses. 

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The Notes contain customary covenants and defaults, including providing financial information, maintenance of business and insurance, collateral matters, and restrictions on the disposition of assets. 

As a result of the Offering, the Bridge Warrants adjusted to be exercisable for an aggregate of 50 million shares at $0.01 per share.

In April 2010, as a result of a previously disclosed court settlement, we issued 5,000,000 shares of common stock in exchange for settlement of $1,005,000 due for previously rendered services.  In accordance with the approved settlement, the number of shares were subject to adjustment based on the Value Weighted Average Price (VWAP) of our common stock 180 days subsequent to the original issuance of the shares, and during October 2010 the shares were adjusted, resulting in an additional 605,000 shares due to the holders of the claims.

Item 2.                 Management's Discussion and Analysis of Financial Condition and Results of Operations

The following discussion of our financial condition and results of operations should be read in conjunction with our financial statements including the related notes, and the other financial information included in this report. For ease of reference, “we,” “us” or “our” refer to Hythiam, Inc., our wholly-owned subsidiaries and The PROMETA Center, Inc. unless otherwise stated.

CAUTIONARY STATEMENT CONCERNING FORWARD-LOOKING INFORMATION

In addition to historical information this report contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995 with respect to the financial condition, results of operations, business strategies, operating efficiencies or synergies, competitive positions, market and industry segment growth opportunities for existing products, plans and objectives of management, markets for stock of Hythiam and other matters. Statements in this report that are not historical facts are hereby identified as “forward-looking statements” for the purpose of the safe harbor provided by Section 21E of the Exchange Act of 1934 and Section 27A of the Securities Act of 1933. Such forward-looking statements, including, without limitation, those relating to the future business prospects, revenue and income of Hythiam, wherever they occur, are necessarily estimates reflecting the best judgment of the senior management of Hythiam on the date on which they were made, or if no date is stated, as of the date of this report. These forward-looking statements are subject to risks, uncertainties and assumptions, including those described in the “Risk Factors” in Item 1A of Part I of our most recent Annual Report on Form 10-K, filed with the SEC, that may affect the operations, performance, development and results of our business. Because the factors discussed in this report could cause actual results or outcomes to differ materially from those expressed in any forward-looking statements made by us or on our behalf, you should not place undue reliance on any such forward-looking statements. New factors emerge from time to time, and it is not possible for us to predict which factors will arise. In addition, we cannot assess the impact of each factor on our business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements. The Company assumes no obligation and does not intend to update these forward-looking statements, except as required by law.

OVERVIEW

General

We are a healthcare services management company, providing through our Catasys® subsidiary behavioral health management services for substance abuse to health plans.  Catasys is focused on offering integrated substance dependence solutions, including our patented PROMETA® Treatment Program, for alcoholism and stimulant dependence. The PROMETA Treatment Program, which integrates behavioral, nutritional, and medical components, is also available on a private-pay basis through licensed treatment providers and a company managed treatment center that offers the PROMETA Treatment Program, as well as other substance dependence and mental health services. We also research, develop, license and commercialize innovative and proprietary physiological, nutritional, and behavioral treatment programs. 

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Discontinued Operations

On January 20, 2009 we sold our entire interest in our controlled subsidiary CompCare for aggregate gross proceeds of $1.5 million. We recognized a gain of approximately $11.2 million from the sale of our CompCare interest, which is included in Results of Discontinued Operations in our Consolidated Statement of Operations for the three months ended March 31, 2009.

Prior to the sale, we reported the operations of CompCare in our behavioral health managed care segment. For detailed information regarding the impact of the sale of our interest in CompCare, see our consolidated financial statements and Note 5 Discontinued Operations included with this report.

Operations

Under our licensing agreements, we provide physicians and other licensed treatment providers access to our PROMETA Treatment Program, education and training in the implementation and use of the licensed technology. The patient’s physician determines the appropriateness of the use of the PROMETA Treatment Program. We receive a fee for the licensed technology and related services generally on a per patient basis. While we continue to maintain licensing agreements with physicians, hospitals and treatment providers for 50 sites throughout the United States, the number of active sites has decreased as a result of our streamline operations, removing field support personnel and significant reductions or eliminations of advertising related to the private pay business. Eleven sites contributed to revenue in the first six months of 2010. We will continue to enter into agreements on a selective basis with additional healthcare providers to increase the availability of the PROMETA Treatment Program, but generally only in markets we are presently operating or where such sites will provide support for our Catasys products.  As such revenues are generally related to the number of patients treated, key indicators of our financial performance for the PROMETA Treatment Program will be the number of facilities and healthcare providers that license our technology, and the number of patients that are treated by those providers using our PROMETA Treatment Program. As discussed below in Recent Developments, we are currently evaluating and considering additional actions to streamline our operations that may impact the licensing operations.

We currently manage, under a licensing agreement, one treatment center located in Santa Monica, California (dba The Center to Overcome Addiction).  We manage the business components of the treatment center and license the PROMETA Treatment Program and use of the name in exchange for management and licensing fees under the terms of full business service management agreements. The center offers treatment with the PROMETA Treatment Program for dependencies on alcohol, cocaine and methamphetamines and also offers medical and psychosocial interventions for other substance dependencies and mental health disorders. The revenues and expenses of these centers are included in our consolidated financial statements under accounting standards applicable to variable interest entities.  As discussed below in Recent Developments, we are currently evaluating and considering additional actions to streamline our operations that may impact the managed treatment center.

Beginning in 2007, we developed our Catasys integrated substance dependence solutions for third-party payors. We believe that our Catasys offerings will address a high cost segment of the healthcare market for substance dependence, and we are currently marketing our Catasys integrated substance dependence solutions to managed care health plans on a case rate or monthly fee, which involves educating third party payors on the disproportionately high cost of their substance dependent population and demonstrating the potential for improved clinical outcomes and reduced cost associated with using our Catasys programs.

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RESULTS OF OPERATIONS

Table of Summary Consolidated Financial Information

The table below and the discussion that follows summarize our results of consolidated continuing operations for the three and nine months ended September 30, 2010 and 2009:

	Three Months Ended						Nine Months Ended
(In thousands, except per share amounts)	September 30,						September 30,
	2010			2009			2010			2009
Revenues
Total revenues	$	104		$	268		$	338		$	1,346
Operating expenses
Cost of healthcare services		99			68			174			502
General and administrative		2,581			3,878			9,254			14,007
Impairment losses		1			-			39			1,113
Depreciation and amortization		204			273			705			979
Total operating expenses		2,885			4,219			10,172			16,601
Loss from operations		(2,781	)		(3,951	)		(9,834	)		(15,255	)
Interest and other income		1			19			129			142
Interest expense		(41	)		(221	)		(312	)		(999	)
Loss on extinguishment of debt		-			(54	)		-			(330	)
Gain on the sale of marketable securities		-			160			696			160
Other than temporary impairment of marketable
securities		(32	)		(25	)		-			(185	)
Change in fair value of warrant liability		913			(4,767	)		1,807			(4,683	)
Loss from continuing operations before provision
for income taxes		(1,940	)		(8,839	)		(7,514	)		(21,150	)

Summary of Consolidated Operating Results

The net loss from continuing operations before provision for income taxes decreased by $6.9 million and $13.6 million during the three and nine months ended September 30, 2010 respectively, compared to the same periods in 2009. The decrease was primarily due to the impact of actions to streamline our Healthcare Services operations and by an increase in the change in fair value of warrant liability of $5.7 million and $6.5 million for the same periods during 2009.

Revenues

Revenue decreased by $164,000 and $1.0 million for the three and nine months ended September 30, 2010, respectively, compared to the same periods in 2009, due mainly to a decline in licensed sites contributing to revenue and in the number of patients treated at our U.S licensed sites and the managed treatment centers, and a decrease in administrative fees earned from licensees. The number of patients treated decreased by 72% and 76% in the three and nine months ended September 30, 2010, respectively, compared to the same periods in 2009. The average revenue per patient treated at U.S. licensed sites and at Company managed centers decreased by approximately $400 and $1,600 during the three and nine months ended September 30, 2010, respectively, compared to the same periods in 2009.

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Cost of Healthcare Services

Cost of healthcare services consists of royalties we pay for the use of the PROMETA Treatment Program, and costs incurred by our consolidated managed treatment center (The Center to Overcome Addiction) for direct labor costs for physicians and nursing staff, continuing care expense, medical supplies and treatment program medicine costs. The decrease in these costs reflects a decrease in revenues from the reduction of treatment centers; management services agreements, licensed sites and corresponding patient volume in the first nine months of 2010.

General and Administrative Expenses

Total general and administrative expenses decreased by $1.3 million and $4.7 million in the three and nine months ended September 30, 2010, respectively, compared to the same periods in 2009. This decrease is attributable to decreases of $456,000 and $2.4 million in salaries and benefits for the three and nine months ended September 30, 2010, respectively, compared to the same periods in 2009.  General and administrative expenses for the first nine months of 2010 include $3.0 million in non-cash expense for share-based compensation, compared to $3.5 million of such expense for the same period in 2009.

Depreciation and amortization decreased by $69,000 and $274,000 during the three and nine months ended September 30, 2010, respectively, compared to the same periods in 2009.

Impairment Losses

There was an impairment loss related to property plant and equipment of $1,000 and $39,000 for the three and nine months ended September 30, 2010, respectively, compared to $0 and $1.1 million for the three and nine months ended September 30, 2009, respectively.  During the three and nine month periods ended September 30, 2009, impairment charges included $122,000 for intangible assets related to our managed treatment center in Dallas and $233,000 related to intellectual property for additional indications for the use of the PROMETA Treatment Program that are currently non-revenue-generating. There was no impairment charge related to intellectual property in the three and nine months ended September 30, 2010.

Interest and other income

      During the three and nine months ended September 30, 2010, we recorded $759,000 and $129,000, respectively, in interest and other income or loss compared to $19,000 and $142,000, respectively, for the three and nine months ended September 30, 2009.

Interest Expense

Interest expense declined by $180,000 and $687,000, respectively, from the three and nine months ended September 30, 2010 compared to the same periods in 2009, primarily due to a reduction of $9.6 million in interest bearing liabilities.

Loss from Extinguishment of Debt

There was no charge for loss from extinguishment of debt during the three and nine months ended September 30, 2010. In the first quarter of 2009 we recognized a $276,000 loss on extinguishment of debt resulting from the $1.4 million pay down on the Highbridge senior secured note, primarily representing unamortized discount.

Gain/(Loss)on Sale of Marketable Securities

As a result of the sale of approximately $10.2 million in ARS, we recorded ($758,000) and $696,000 of gain on sale of marketable securities for the three and nine months ended September 20, 2010, respectively.

Other than Temporary Impairment on Marketable Securities

There was no impairment charge related to certain ARS during the three and nine months ended September 30, 2010 compared to $25,000 and $185,000, respectively, for the same periods in 2009. The charge was based on an updated valuation of the securities

29

performed by management as of March 31, 2009 and deemed necessary after an analysis of other-than-temporary impairment factors, most notably, our inability to hold the ARS until they might recover in value.

Change in fair value of warrant liability

We issued warrants in connection with our registered direct stock placements completed in November 2007, September 2009 and July 2010, and the amended and restated Highbridge senior secured note in July 2008. The warrants are being accounted for as liabilities in accordance with FASB accounting rules, due to provisions in some warrants that protect the holders from declines in the Company’s stock price and a requirement to deliver registered shares upon exercise of the warrants, which is considered outside the control of the Company.  The warrants are marked-to-market each reporting period, using the Black-Scholes pricing model, until they are completely settled or expire.

The change in fair value of the warrants for the three and nine months ended September 30, 2010 and 2009 was gains/(losses) $913,000, $1.8 million, $(4.8) million and $(4.7) million, respectively. We will continue to mark the warrants to market value each quarter-end until they are completely settled.

LIQUIDITY AND CAPITAL RESOURCES

Liquidity and Going Concern

As of September 30, 2010, we had a balance of approximately $363,000 in cash, cash equivalents. We had a working capital deficit of approximately $3.5 million at September 30, 2010.  We have incurred significant net losses and negative operating cash flows since our inception. We expect to continue to incur negative cash flows and net losses for the next twelve months. In July 2010 we closed on $2 million of a registered direct financing with certain institutional investors which represented $1.7 million in net proceeds to the Company.

In October 2010, Hythiam, Inc. (the “Company”) entered into Securities Purchase Agreements (the “Agreements”) with accredited investors, for $500,000 of 12% senior secured convertible notes (the “Bridge Notes”) and warrants to purchase shares of our common stock (the “Bridge Warrants”) (see Note 7 Subsequent Events).

In November 2010, the Company completed a private placement with certain accredited investors. Investors included Socius Capital Group, LLC, an affiliate of our Chairman and CEO, and a Hythiam director (see Note 7 Subsequent Events). This transaction should provide enough working capital into late 2011. In addition, all of the holders of Bridge Notes exchanged the Bridge Notes plus interest into securities issued in this financing. The Company had approximately $6.1 million after this transaction and as of this report date.

Our ability to fund our ongoing operations and continue as a going concern is dependent on signing and generating revenue from new contracts for our Catasys managed care programs and the success of management’s plans to increase revenue and continue to decrease expenses. We are currently in the process of implementing our recent Catasys contract in Nevada and we expect that contract to become operational in the fourth quarter of 2010. Beginning in the fourth quarter of 2008, and continuing in each of the quarters during 2010, management took actions that have resulted in reducing annual operating expenses.  We have renegotiated certain leasing and vendor agreements to obtain more favorable pricing and to restructure payment terms with vendors, and have paid some expenses through the issuance of common stock. We amended the lease on premises which resulted in deferring payments and agreed to settle a lawsuit filed by a landlord in March 2010 related to a facility that is no longer in use. This amendment and the legal settlement require payments aggregating $234,000 between July 1, 2010 and February 2011. To date we have made all payments under these arrangements as they have come due with only $72,000 remaining as of this report date. In addition, during the nine months ended September 30, 2010, we settled, through the issuance of common stock, approximately $1.2 million of liabilities. In previous periods, we have exited markets for our licensee operations that we have determined would not provide short-term profitability. We may exit additional markets for our licensee operations and further curtail or restructure our managed treatment center to reduce costs if management determines that those markets are not expected to provide short-term

30

profitability and/or positive cash flow. We do not expect any direct costs associated with streamlining our organization to have a material positive impact on our cash position or our ability to continue as a going concern.

Cash Flows

We used $5.4 million of cash for continuing operating activities during the nine months ended September 30, 2010 compared to $11.0 million of cash for continuing operating activities during the same period last year. Use of funds in operating activities include general and administrative expense (excluding share-based expense), and the cost of healthcare services revenue, which totaled approximately $3.1 million for the nine months ended September 30, 2010, compared to $4.0 million for the same period in 2009. This decrease in net cash used reflects the decline in such expenses from our efforts to streamline operations.

Capital expenditures for the nine months ended September 30, 2010 were not material. Our future capital expenditure requirements will depend upon many factors, including progress with our marketing efforts, the time and costs involved in preparing, filing, prosecuting, maintaining and enforcing patent claims and other proprietary rights, the necessity of, and time and costs involved in obtaining, regulatory approvals, competing technological and market developments, and our ability to establish collaborative arrangements, effective commercialization, marketing activities and other arrangements.

Highbridge Senior Secured Note

On August 11, 2009, we amended our amended and restated senior secured note with Highbridge International LLC (Highbridge), to extend the maturity date from January 15, 2010 to July 15, 2010, and Highbridge agreed to give up its optional redemption rights. We also committed to exercising our right to sell our ARS in accordance with the terms of the rights offering by UBS, who sold them to us, and use the proceeds from the sale to redeem the note. The amended note also called for redemption of the note at 110% by applying a portion of any borrowed or raised capital. We also amended all 1.8 million warrants that had been previously issued to Highbridge to purchase shares of our common stock (including 1.3 million issued in conjunction with the amended and restated note in 2008 and 540,000 issued in conjunction with the November 2007 registered direct financing), to change the exercise price to $0.28 per share, and extend the expiration date to five years from the amendment date. During the three months ended March 31, 2009, we drew down an additional $1.5 million under the UBS demand margin loan facility, and used $1.4 million of the proceeds to pay down the principal balance on our senior secured note with Highbridge International

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LLC. During April and July 2010, we issued common stock which triggered an anti-dilution adjustment to the 1.3 million warrants associated with the 2008 amended and restated senior and secured note held by Highbridge LLC. The adjustment resulted in an increase to the number of warrants outstanding in the amount of 72.000 and a decrease in the exercise price from $0.28 to $0.27 per share. We paid this note in full upon maturity in July 2010.

UBS Line of Credit

In May 2008, our investment portfolio manager, UBS, provided us with a demand margin loan facility collateralized by our ARS, which allowed us to borrow up to 50% of the UBS-determined market value of our ARS.

In October 2008, UBS made a “Rights” offering to its clients pursuant to which we were entitled to sell to UBS all ARS held in our UBS account. As part of the offering, UBS provided us a line of credit (replacing the demand margin loan), subject to certain restrictions as described in the prospectus, equal to 75% of the market value of the ARS, until they are purchased by UBS. We accepted the UBS offer on November 6, 2008. Loans under the line of credit were subject to a rate of interest based upon the current 90-day U.S Treasury bill rate plus 120 basis points, payable monthly and were carried in short-term liabilities on our Condensed Consolidated Balance at December 31, 2009. As of June 30 2010 all ARS were redeemed at par and the line of credit was paid in full.

CONTRACTUAL OBLIGATIONS AND COMMERCIAL COMMITMENTS

The following table sets forth a summary of our material contractual obligations and commercial commitments as of September 30, 2010 (in thousands):

		Less than	1 - 3	3 - 5	More than
Contractual Commitments	Total	1 year	years	years	5 years
Outstanding Debt Obligations	$             -	$             -
Capital Lease  Obligations	73	65	8	-	-
Operating Lease Obligations	355	340	15	-	-
Clinical Studies	356	356	-	-	-
Total	$          784	$          761	$          23	$           -	$             -

OFF BALANCE SHEET ARRANGEMENTS

As of September 30, 2010 we had no off-balance sheet arrangements.

CRITICAL ACCOUNTING ESTIMATES

Critical Accounting Estimates

The discussion and analysis of our financial condition and results of operations is based upon our financial statements, which have been prepared in accordance with U.S. generally accepted accounting principles (“GAAP”). GAAP requires management to make estimates, judgments and assumptions that affect the reported amounts of assets, liabilities, revenues and expenses, and the disclosure of contingent assets and liabilities. We base our estimates on experience and on various other assumptions that we believe to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that may not be readily apparent from other sources. On an on-going basis, we evaluate the appropriateness of our estimates and we maintain a thorough process to review the application of our accounting policies. Our actual results may differ from these estimates.

We consider our critical accounting estimates to be those that (1) involve significant judgments and uncertainties, (2) require estimates that are more difficult for management to determine, and (3) may produce materially different results when using different assumptions. We have discussed these critical accounting estimates, the basis for their underlying assumptions and estimates and the nature of our related disclosures herein with the audit committee of our Board of Directors. We believe our accounting policies specific to share-based compensation expense; the impairment assessments for intangible assets, valuation of derivative liabilities, and valuation of

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marketable securities involve our most significant judgments and estimates that are material to our consolidated financial statements. They are discussed further below.

Warrant Liabilities

We have issued warrants in connection with the registered direct placements of our common stock in November 2007, September 2009, July 2010, Bridge Financing, November financings noted below, and the amended and restated Highbridge senior secured note in July 2008. The warrant agreements include provisions that require us to record them as a liability, at fair value, pursuant to FASB accounting rules and include provisions in some warrants that protect the holders from declines in the Company’s stock price and a requirement to deliver registered shares upon exercise, which is considered outside the control of the Company. The warrant liabilities are marked-to-market each reporting period and changes in fair value are recorded as a non-operating gain or loss in our statement of operations, until they are completely settled or expire. The fair value of the warrants is determined each reporting period using the Black-Scholes option pricing model, and is affected by changes in inputs to that model including our stock price, expected stock price volatility, interest rates and expected term.

The change in fair value of the warrant liabilities amounted to net gains of $913,000 and $1.8 million for the three and nine months ended September 30, 2010, compared to net losses of $4.8 million and $4.7 million for the same periods in 2009. The gains resulted mainly from a decline in the Company’s stock price. We will continue to re-measure the warrant liabilities at fair value each quarter-end until they are completely settled or expire.

In October 2010, the Company entered into Securities Purchase Agreements, for $500,000 of senior secured convertible notes (the “Bridge Notes”) and warrants to purchase shares of our common stock (the “Bridge Warrants”). The investors received warrants to purchase an aggregate 12,500,000 shares of Company common stock at $.04 per share (see Note 7 Subsequent Events).

In November 2010, the Company completed a private placement with accredited investors, in the amount of $6.9 million (the “Offering”). In addition, investors investing $2,000,000 or more also received warrants to purchase 21,960,000 shares of Company common stock at $.01 per share (see Note 7 Subsequent Events).

Share-based expense

Commencing January 1, 2006, we implemented the accounting provisions of Statement of Financial Accounting Standards (SFAS) 123R on a modified-prospective basis to recognize share-based compensation for employee stock option awards in our statements of operations for future periods. We accounted for the issuance of stock, stock options and warrants for services from non-employees in accordance with SFAS 123, Accounting for Stock-Based Compensation and FASB Emerging Issues Task Force Issue No. 96-18, Accounting For Equity Instruments That Are Issued To Other Than Employees For Acquiring Or In Conjunction With Selling Goods Or Services . We estimate the fair value of options and warrants issued using the Black-Scholes pricing model. This model’s calculations include the exercise price, the market price of shares on grant date, weighted average assumptions for risk-free interest rates, expected life of the option or warrant, expected volatility of our stock and expected dividend yield.

The amounts recorded in the financial statements for share-based expense could vary significantly if we were to use different assumptions. For example, the assumptions we have made for the expected volatility of our stock price have been based on the historical volatility of our stock measured over a period generally commensurate with the expected term, since we have a limited history as a public company and complete reliance on our actual stock price volatility would not be meaningful. If we were to use the actual volatility of our stock price, there may be a significant variance in the amounts of share-based expense from the amounts reported. Based on the 2008 assumptions used for the Black-Scholes pricing model, a 50% increase in stock price volatility would have increased the fair values of options by approximately 25%. The weighted average expected option term for 2008, 2007 and 2006 reflects the application of the simplified method set out in SEC Staff Accounting Bulletin No. 107, which defines the life as the average of the contractual term of the options and the weighted average vesting period for all option tranches.

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From time to time, we have retained terminated employees as part-time consultants upon their resignation from the company. Because the employees continued to provide services to us, their options continued to vest in accordance with the original terms. Due to the change in classification of the option awards, the options were considered modified at the date of termination in accordance with SFAS 123R. The modifications were treated as exchanges of the original awards in return for the issuance of new awards. At the date of termination, the unvested options were no longer accounted for as employee awards under SFAS 123R and were accounted for as new non-employee awards under EITF 96-18. The accounting for the portion of the total grants that have already vested and have been previously expensed as equity awards is not changed.

Impairment of Intangible Assets

We have capitalized significant costs for acquiring patents and other intellectual property directly related to our products and services. We review our intangible assets for impairment whenever events or circumstances indicate that the carrying amount of these assets may not be recoverable. In reviewing for impairment, we compare the carrying value of such assets to the estimated undiscounted future cash flows expected from the use of the assets and/or their eventual disposition. If the estimated undiscounted future cash flows are less than their carrying amount, we record an impairment loss to recognize a loss for the difference between the assets’ fair value and their carrying value. Since we have not recognized significant revenue to date, our estimates of future revenue may not be realized and the net realizable value of our capitalized costs of intellectual property or other intangible assets may become impaired.

During the nine months ended September 30, 2010 we did not acquire any new intangible assets and at September 30, 2009, all of our intangible assets consisted of intellectual property, which is not subject to renewal or extension. We performed impairment tests on intellectual property as of September 30, 2010 and after considering numerous factors, we determined that the carrying value of certain intangible assets was recoverable as of September 30, 2010.  During the nine months ended September 30, 2010 we did not record impairment charges associated with our intellectual property. At March 31, 2010, we had an independent third-party perform a valuation of our intellectual property. They relied on the “relief from royalty” method, as this method was deemed to be most relevant to the intellectual property assets of the Company.  We determined that the estimated useful lives of the remaining intellectual property properly reflected the current remaining economic useful lives of the assets.

Valuation of Marketable Securities

Investments include ARS and certificates of deposit with maturity dates greater than three months when purchased, which are classified as available-for-sale investments and reflected in current or long-term assets, as appropriate, as marketable securities at fair market value. Unrealized gains and losses are reported in our Condensed Consolidated Balance Sheet within accumulated other comprehensive loss and within other comprehensive loss. Realized gains and losses and declines in value judged to be “other-than-temporary” are recognized as a non-reversible impairment charge in the Statement of Operations on the specific identification method in the period in which they occur.

We regularly review the fair value of our investments. If the fair value of any of our investments falls below our cost basis in the investment, we analyze the decrease to determine whether it represents an other-than-temporary decline in value. In making our determination for each investment, we consider the following factors:

●   How long and by how much the fair value of the investments have been below cost;

●   The financial condition of the issuers;

●   Any downgrades of the investment by rating agencies;

●   Default on interest or other terms; and

●   Our intent and ability to hold the investments long enough for them to recover their value.

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RECENT ACCOUNTING PRONOUNCEMENTS

Recently Adopted

In February 2010, the FASB issued ASU 2010-09, “Subsequent Events, Amendments to Certain Recognition and Disclosure Requirements” which made a number of changes to the existing requirements to the FASB Accounting Standards Codification 855 Subsequent Events. The amended guidance was effective upon issuance and as a result of the amendments, SEC filers that file financial statements after February 24, 2010 are not required to disclose the date through which subsequent events have been evaluated. This ASU was adopted as of September 30, 2010 and did not have a material impact on our consolidated financial statements.

In January 2010, the FASB issued ASU 2010-06, “Fair Value Measurements and Disclosures: Improving Disclosures about Fair Value Measurements” which is intended to enhance the usefulness of fair value measurements by requiring both the disaggregation of the information in certain existing disclosures, as well as the inclusion of more robust disclosures about valuation techniques and inputs to recurring and non-recurring fair value measurements. The amended guidance is effective for interim and annual reporting periods beginning after December 15, 2009, except for the disaggregation requirement for the reconciliation disclosure of Level 3 measurements, which is effective for fiscal years beginning after December 31, 2010 and for interim periods within those years. This ASU was adopted as of September 30, 2010 and did not have a material impact on our consolidated financial statements.

In January 2010, the FASB issued ASU 2010-02, “Accounting and Reporting for Decreases in Ownership of a Subsidiary – Scope Clarification” which is intended to clarify which transactions require a decrease in ownership provisions particularly for non-controlling interests in consolidated financial statements. In addition, it requires increased disclosures about deconsolidation of a subsidiary. It requires retrospective application and is effective for the first interim or annual periods ending on or after December 15, 2009. Adoption of this ASU will not have a material impact on our consolidated financial statements.

In January 2010, the FASB issued ASU 2020-01 “Accounting for Distributions to Shareholders with Components of Stock and Cash” which is intended to clarify the accounting treatment for a stock portion of a shareholder distribution that (1) contains both cash and stock components, (2) allows shareholders to select their preferred form of distribution, and (3) limits the total amount of cash to be distributed. It defines a stock dividend as a dividend that takes nothing from the property of an entity and adds nothing to the interests of an entity’s shareholders because the proportional interest of each shareholder remains the same. The stock portion of the distribution must be treated as a stock issuance and be reflected in the EPS calculation prospectively. It requires retrospective application and is effective for annual periods ending on or after December 15, 2009. Adoption of this ASU will not have a material impact on our consolidated financial statements.

In August 2009, the FASB issued ASU 2009-15, which changes the fair value accounting for liabilities. These changes clarify existing guidance that in circumstances in which a quoted price in an active market for the identical liability is not available, an entity is required to measure fair value using either a valuation technique that uses a quoted price of either a similar liability or a quoted price of an identical or similar liability when traded as an asset, or another valuation technique that is consistent with the principles of fair value measurements, such as an income approach (e.g., present value technique). This guidance also states that both a quoted price in an active market for the identical liability and a quoted price for the identical liability when traded as an asset in an active market when no adjustments to the quoted price of the asset are required are Level 1 fair value measurements. This ASU was adopted effective on January 1, 2010 and did not have a material impact on our consolidated financial statements.

In June 2009, the FASB issued ASU 2009-17, “Improvements to Financial Reporting by Enterprises Involved with Variable Interest Entities,” the FASB issued changes to the accounting for variable interest entities. These changes require an enterprise to perform an analysis to determine whether the enterprise’s variable interest or interests give it a controlling financial interest in a variable interest entity; to require ongoing reassessments of whether an enterprise is the primary beneficiary of a variable interest entity; to eliminate the quantitative approach previously required for determining the primary beneficiary of a variable interest entity; to add an additional reconsideration event for determining whether an entity is a variable interest entity when any changes in facts and circumstances occur such that holders of the equity investment at risk, as a group, lose the power from voting rights or similar rights of those investments to direct the activities of the entity that most significantly impact the entity’s

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economic performance; and to require enhanced disclosures that will provide users of financial statements with more transparent information about an enterprise’s involvement in a variable interest entity. These changes became effective for us beginning on January 1, 2010. The adoption of this change did not have a material impact on our consolidated financial statements.

In June 2009, the FASB issued ASU 2009-16, “Accounting for Transfers of Financial Assets,” which changes the accounting for transfers of financial assets. These changes remove the concept of a qualifying special-purpose entity and remove the exception from the application of variable interest accounting to variable interest entities that are qualifying special-purpose entities; limits the circumstances in which a transferor derecognizes a portion or component of a financial asset; defines a participating interest; requires a transferor to recognize and initially measure at fair value all assets obtained and liabilities incurred as a result of a transfer accounted for as a sale; and requires enhanced disclosure; among others. These changes became effective January 1, 2010 and did not have a material impact on our financial statements.

Recently Issued

The following Accounting Standards Updates were issued between December 2009 and September 30, 2010 and contain amendments and technical corrections to certain SEC references in FASB’s codification:

In April 2010, the FASB issued ASU 2010-13, “Share-based payment awards denominated in certain currencies” provides clarification on an employee share-based payment award that has an exercise price denominated in the currency of the market in which a substantial portion of the entity’s equity shares trades should not be considered to contain a condition that is not a market, performance, or service condition. Therefore, an entity should not classify such an award as a liability if it otherwise qualifies as equity. The amended guidance is effective for fiscal years, and interim periods within those fiscal years, beginning on or after December 15, 2010. The Company expects to adopt the amended guidance on January 1, 2011. The Company does not believe that the adoption of the amended guidance will have a significant effect on its consolidated financial statements.

In April 2010, the FASB issued ASU 2010-17, “Milestone Method of Revenue Recognition” guidance to address accounting for research or development arrangements in which a vendor satisfies its performance obligations over time, with all or a portion of the consideration contingent on future events, referred to as milestones. The new guidance allows a vendor to adopt an accounting policy to recognize all of the arrangement consideration that is contingent on the achievement of a milestone in the period the milestone is achieved, if the milestone meets the criteria to be considered a substantive milestone. The milestone method described in the new guidance is not the only acceptable revenue attribution model for milestone consideration. However, other methods that result in the recognition of all of the milestone consideration in the period the milestone is achieved are precluded. A vendor is not precluded from electing to apply a policy that results in the deferral of some portion of the milestone consideration. The new guidance is effective on a prospective basis for milestones achieved in fiscal years, and interim periods within those fiscal years, beginning on or after June 15, 2010, with early adoption permitted. If an entity early adopts in a period that is not the beginning of its fiscal year, it must apply the guidance retrospectively from the beginning of the year of adoption. A vendor may elect to adopt the new guidance retrospectively for all prior periods, but is not required to do so. The Company is still evaluating the effect, if any, and the impact the amended guidance may have on its consolidated financial statements.

Item 3.                 Quantitative and Qualitative Disclosures About Market Risk

Not applicable.

Item 4.                 Controls and Procedures

We have evaluated, with the participation of our chief executive officer and our chief financial officer, the effectiveness of our system of disclosure controls and procedures as of the end of the period covered by this report. Based on this evaluation our chief executive officer and our chief financial officer have determined that they are effective in connection with the preparation of this report.  There were no changes in the internal controls over financial reporting that occurred during the quarter ended September 30, 2010 that have materially affected, or are reasonably likely to materially affect, our internal control over financial reporting.

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PART II – OTHER INFORMATION

Item 1.                 Legal Proceedings

From time to time, we may be involved in litigation relating to claims arising out of our operations in the normal course of business.   

As of the date of this report, we are not currently involved in any material legal proceeding that we believe would have a material adverse effect on our business, financial condition or operating results.

Item 2.                 Unregistered Sales of Equity Securities and Use of Proceeds

The information set forth in Item 5. “Recent Sales of Unregistered Securities” in our Annual Report on form 10-K for the year ended December 31, 2009 is incorporated by reference.

In October 2010, Hythiam, Inc. (the “Company”) entered into Securities Purchase Agreements (the “Agreements”) with accredited investors, including Socius Capital Group, LLC, an affiliate of our Chairman and CEO, for $500,000 of senior secured convertible notes (the “Notes”) and warrants to purchase shares of our common stock (the “Warrants”) (see Note 7 Subsequent Events).

In November 2010, the Company completed a private placement with certain accredited investors for gross proceeds of $6.9 million. Investors included Socius Capital Group, LLC, an affiliate of our Chairman and CEO, and one other Hythiam director (see Note 7 Subsequent Events).

Item 3.                 Defaults Upon Senior Securities

None.

Item 4.                 [Removed and Reserved]

Item 5.                 Other Information

Related Party Transactions

In October 2010, the Company entered into Securities Purchase Agreements with accredited investors, including Socius Capital Group, LLC, an affiliate of our Chairman and CEO, for $500,000 of senior secured convertible notes (the “Bridge Notes”) and warrants to purchase shares of our common stock (the “Bridge Warrants”) (see Note 7 Subsequent Events).

In November 2010, Hythiam, Inc. (the “Company”) completed a private placement with accredited investors for gross proceeds of $6.9 million, including Socius Capital Group, LLC, an affiliate of our Chairman and CEO, and one other Hythiam director (see Note 7 Subsequent Events).

Item 6.                 Exhibits

Exhibit 10.33	Securities Purchase Agreement dated November __, 2010
Exhibit 10.34	Secured Convertible Promissory Note dated November __, 2010
Exhibit 10.35	Security Interest Agreement dated November __, 2010
Exhibit 31.1	Certification of Chief Executive Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
Exhibit 31.2	Certification of Chief Financial Officer pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
Exhibit 32.1	Certification of Chief Executive Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
Exhibit 32.2	Certification of Chief Financial Officer pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

	HYTHIAM, INC.
Date:   November 18, 2010	By:	/s/ TERREN S. PEIZER
		Terren S. Peizer
		Chief Executive Officer (Principal Executive Officer)
Date:   November 18, 2010	By:	/s/ PETER L. DONATO
		Peter L. Donato
		Chief Financial Officer (Principal Financial and Accounting Officer)

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