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LICENSE AGREEMENTS (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Apr. 28, 2021
USD ($)
Mar. 31, 2022
USD ($)
Sep. 30, 2023
USD ($)
Mar. 31, 2023
USD ($)
Sep. 30, 2022
USD ($)
Mar. 31, 2022
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2023
EUR (€)
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
Jan. 24, 2022
USD ($)
LICENSE AGREEMENTS                      
Milestone payment received             $ (1,089,977)   $ 28,408,434    
Revenue     $ 6,185,814   $ 1,591,566   13,089,977   $ 1,591,566    
Deferred revenue, current     25,405,084       25,405,084     $ 17,980,599  
Deferred revenue, net of current     953,470       953,470     $ 9,467,932  
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                      
LICENSE AGREEMENTS                      
Potential milestone payments     100,000,000.0       100,000,000.0        
Upfront Payment           $ 30,000,000.0          
Deferred revenue liability   $ 30,000,000.0 14,400,000     30,000,000.0 14,400,000        
Revenue     6,200,000       13,100,000        
Deferred revenue, current     13,400,000       13,400,000        
Deferred revenue, net of current     $ 1,000,000.0       $ 1,000,000.0        
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2023-07-01                      
LICENSE AGREEMENTS                      
Revenue, Remaining Performance Obligation, Percentage     93.00%       93.00%        
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period     3 months       3 months        
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2024-07-01                      
LICENSE AGREEMENTS                      
Revenue, Remaining Performance Obligation, Percentage     93.00%       93.00%        
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period     12 months       12 months        
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan                      
LICENSE AGREEMENTS                      
Potential milestone payments       $ 89,000,000              
Upfront Payment       12,000,000.0              
Milestone payment received       $ 12,000,000.0              
Deferred revenue liability     $ 12,000,000.0       $ 12,000,000.0        
Deferred revenue, current     12,000,000.0       $ 12,000,000.0        
Rome License Agreement                      
LICENSE AGREEMENTS                      
Notice period             90 days 90 days      
JHU License Agreement                      
LICENSE AGREEMENTS                      
Notice period             60 days 60 days      
Milestone payments to be made upon completion of certain phases   500,000       $ 500,000          
Threshold period to cure breach             30 days 30 days      
CSMC License Agreement                      
LICENSE AGREEMENTS                      
Notice period             90 days 90 days      
Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Notice period 90 days           90 days 90 days      
Upfront Payment $ 10,000                    
Minimum | Rome License Agreement                      
LICENSE AGREEMENTS                      
Minimum annual royalty payments | €               € 20,000      
Maximum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                      
LICENSE AGREEMENTS                      
Potential milestone payments                     $ 705,000,000.0
Maximum | JHU License Agreement                      
LICENSE AGREEMENTS                      
Potential milestone payments     $ 1,850,000       $ 1,850,000        
Completion Of Phase Two Due | JHU License Agreement                      
LICENSE AGREEMENTS                      
Milestones paid   $ 250,000                  
Patent rights | JHU License Agreement                      
LICENSE AGREEMENTS                      
Agreement effective period             20 years 20 years      
Patent rights | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Agreement effective period 20 years                    
Particular Patent or Application or Any Particular Licensed Product | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Notice period 60 days                    
Non Payment of Royalties | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period             30 days 30 days      
Non Payment of Royalties | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach             30 days 30 days      
CSMC Agreement Compliance | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period             90 days 90 days      
CSMC Agreement Compliance | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach             90 days 90 days      
Material Breach Has Not Been Cured | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period             90 days 90 days      
Material Breach Has Not Been Cured | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach             90 days 90 days      
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period             90 days 90 days      
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach 60 days           90 days 90 days