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Stock-Based Compensation Plan - Option Activity Under Plan (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Stock-Based Compensation Plan      
Outstanding 274 68  
Granted 213 211  
Forfeited   (4)  
Expired (1) (1)  
Outstanding 486 274 68
Vested and expected to vest 451 238  
Exercisable 178 66  
Weighted-Average Exercise Price, Outstanding $ 20.57 $ 68.56  
Weighted-Average Exercise Price, Granted 7.02 5.01  
Weighted-Average Exercise Price, Forfeited   7.19  
Weighted-Average Exercise Price, Expired 72.67 28.67  
Weighted-Average Exercise Price, Outstanding 14.58 20.57 $ 68.56
Weighted - Average Exercise Price, Vested and expected to vest 15.21 22.66  
Weighted-Average Exercise Price, Exercisable $ 28.09 $ 63.95  
Weighted Average Remaining Contractual Term (In years), Outstanding 8 years 4 months 24 days 8 years 8 months 12 days 7 years 8 months 12 days
Weighted Average Remaining Contractual Term (In years), Granted 9 years 3 months 18 days 9 years 4 months 24 days  
Weighted Average Remaining Contractual Term (In years), Vested and expected to vest 8 years 4 months 24 days 8 years 8 months 12 days  
Weighted Average Remaining Contractual Term (In years), Exercisable 7 years 7 months 6 days 7 years 2 months 12 days  
Aggregate Intrinsic Value, Outstanding $ 3,750    
Aggregate Intrinsic Value, Outstanding 7,800 $ 3,750  
Aggregate Intrinsic Value, Vested and expected to vest 7,114    
Aggregate Intrinsic Value, Exercisable $ 3,412 $ 3,070