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Stock-Based Compensation Plan - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Stock Based Compensation Plans [Line Items]      
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant 60,000    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value $ 26.55 $ 120.00  
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options $ 0.8    
Stock-based compensation expense $ 0.6 $ 0.8  
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term 7 years 6 months 4 years 5 years 2 months 12 days
Research and Development Expense      
Stock Based Compensation Plans [Line Items]      
Stock-based compensation expense $ 0.1 $ 0.3  
General and Administrative Expense      
Stock Based Compensation Plans [Line Items]      
Stock-based compensation expense $ 0.5 $ 0.5