Warrant Liability

12 Months Ended

Dec. 31, 2018

In connection with the 2016 Registered Direct Offering, the Company issued warrants to purchase up to 14,706 shares of the Company’s common stock at $460.00 per share to certain healthcare focused institutional investors, as well as warrants to purchase up to 1,250 shares of the Company’s common stock at $492.00 per share to H.C. Wainwright & Co., LLC and its designees as compensation for its services as the placement agent. When issued, the 2016 Warrants contained a provision for net cash settlement in the event of certain fundamental transactions involving the Company (defined in the 2016 Warrants to include, among other things, the Company’s approval and consummation of a merger with another entity, the Company’s approval and consummation of the sale of all or substantially all of the Company’s assets or the occurrence of certain other change of control transactions). Due to this provision and in accordance with ASC 480-10 (Distinguishing Liabilities from Equity), the 2016 Warrants were classified as a liability and recorded at fair value as calculated using the Binomial Lattice Model.

As discussed in Note 1, certain of the 2016 Warrants were extinguished in 2017 as a result of the Exercise Agreements and resulted in recognition of a loss on extinguishment of warrants of $0.4 million. Additionally, warrants with a fair value of $0.2 million were reclassified to equity as a result of the Warrant Amendments. For the years ended December 31, 2018 and 2017, the net change in fair value of the 2016 Warrants of none and $2.4 million respectively, are shown as other income on the Company’s Consolidated Statements of Operations.